Defining disease severity in atopic dermatitis and psoriasis for the application to biomarker research- an inter-disciplinary perspective.
Autorzy:
Ramessur R; St John's Institute of Dermatology, School of Basic & Medical Biosciences and Department of Medical & Molecular Genetics, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK. Dand N; Department of Medical and Molecular Genetics, School of Basic & Medical Biosciences, King's College London. Langan SM; London School of Hygiene & Tropical Medicine, London, UK. Saklatvala J; Department of Medical and Molecular Genetics, School of Basic & Medical Biosciences, King's College London. Fritzsche MC; Institute of History and Ethics in Medicine, TUM School of Medicine, Technical University of Munich, Munich, Germany.; Department of Science, Technology and Society, School of Social Sciences and Technology, Technical University of Munich, Munich, Germany. Holland S; Eczema Outreach Support. Arents BWM; Dutch Association for People with Atopic Dermatitis, Nijkerk, The Netherlands. McAteer H; The Psoriasis Association, UK. Proctor A; National Eczema Society, UK. McMahon D; Irish Skin Foundation. Greenwood M; Irish Skin Foundation. Buyx AM; Institute of History and Ethics in Medicine, TUM School of Medicine, Technical University of Munich, Munich, Germany.; Department of Science, Technology and Society, School of Social Sciences and Technology, Technical University of Munich, Munich, Germany. Messer T; EURICE - European Research and Project Office GmbH, St. Ingbert, Germany. Weiler N; EURICE - European Research and Project Office GmbH, St. Ingbert, Germany. Hicks A; Immunology & Inflammation Research Therapeutic Area, Sanofi, Cambridge, Massachusetts, USA. Hecht P; Public Private Partnerships, Sanofi Partnering, Frankfurt am Main, Germany. Weidinger S; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany. Ndlovu MN; UCB Pharma, Brussels, Belgium. Chengliang D; Translational Medicine Department, UCB S.A., London, UK. Hübenthal M; Department of Dermatology, Quincke Research Center, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. Egeberg A; Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. Paternoster L; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School. Skov L; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Dermatology and Allergy, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark. De Jong EMGJ; Department of Dermatology, Radboud University Medical Centre, Nijmegen, The Netherlands. Middelkamp-Hup MA; Department of Dermatology, Amsterdam Public Health, Infection and Immunity, Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Mahil SK; St John's Institute of Dermatology, School of Basic & Medical Biosciences and Department of Medical & Molecular Genetics, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK. BarkerJN; St John's Institute of Dermatology, School of Basic & Medical Biosciences and Department of Medical & Molecular Genetics, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK. Flohr C; Unit for Paediatric & Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust and King's College London, London, UK. Brown SJ; Centre for Genomic and Experimental Medicine, University of Edinburgh, Scotland, UK.; Department of Dermatology, NHS Lothian, Edinburgh, Scotland, UK. Smith CH; St John's Institute of Dermatology, School of Basic & Medical Biosciences and Department of Medical & Molecular Genetics, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockade.
Autorzy:
Francis L; St John's Institute of Dermatology, King's College London and Guy's and St Thomas' NHS Foundation Trust, London, UK. McCluskey D; Department of Medical and Molecular Genetics, King's College London, London, UK. Ganier C; Center of Gene Therapy and Regenerative Medicine, King's College London, London, UK. Jiang T; St John's Institute of Dermatology, King's College London and Guy's and St Thomas' NHS Foundation Trust, London, UK. Du-Harpur X; Center of Gene Therapy and Regenerative Medicine, King's College London, London, UK. Gabriel J; Center of Gene Therapy and Regenerative Medicine, King's College London, London, UK. Dhami P; Genomics Research Platform, King's College London NIHR Biomedical Research Centre, London, UK. Kamra Y; Genomics Research Platform, King's College London NIHR Biomedical Research Centre, London, UK. Visvanathan S; Boehringer Ingelheim Pharmaceuticals, Ridgefield, USA. BarkerJN; St John's Institute of Dermatology, King's College London and Guy's and St Thomas' NHS Foundation Trust, London, UK. Smith CH; St John's Institute of Dermatology, King's College London and Guy's and St Thomas' NHS Foundation Trust, London, UK. Capon F; Department of Medical and Molecular Genetics, King's College London, London, UK. . Mahil SK; St John's Institute of Dermatology, King's College London and Guy's and St Thomas' NHS Foundation Trust, London, UK. .
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Źródło:
Nature communications [Nat Commun] 2024 Jan 30; Vol. 15 (1), pp. 913. Date of Electronic Publication: 2024 Jan 30.
The association of age at psoriasis onset and HLA-C*06:02 with biologic survival in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).
Autorzy:
Alabas OA; Dermatology Centre, Northern Care Alliance NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, UK. On behalf of the BADBIR study group. Mason KJ; Primary Care Centre Versus Arthritis, School of Medicine, Keele University, Keele, UK. Yiu ZZN; Dermatology Centre, Northern Care Alliance NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, UK. On behalf of the BADBIR study group. Warren RB; Dermatology Centre, Northern Care Alliance NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, UK. On behalf of the BADBIR study group. Dand N; Department of Medical and Molecular Genetics, School of Basic & Medical Biosciences, King's College London, UK. BarkerJN; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. On behalf of BSTOP study group. Smith CH; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. On behalf of BSTOP study group. Griffiths CEM; Dermatology Centre, Northern Care Alliance NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, UK. On behalf of the BADBIR study group.
Prospective analysis to determine barriers to allogeneic hematopoietic cell transplantation in patients with acute leukemia.
Autorzy:
Nath K; Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Lee J; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Elko TA; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Levy L; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Preston E; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Devlin SM; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Ponce DM; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Lin RJ; Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Shaffer BC; Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Cho C; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Politikos I; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Jakubowski AA; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Park JH; Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Rampal R; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Perales MA; Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Tallman MS; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. BarkerJN; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Berman E; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Tamari R; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Stein E; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Giralt SA; Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Gyurkocza B; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.
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Źródło:
American journal of hematology [Am J Hematol] 2023 Dec; Vol. 98 (12), pp. 1869-1876. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Observational Study; Journal Article; Research Support, N.I.H., Extramural
The Simplified Comorbidity Index predicts non-relapse mortality in reduced-intensity conditioning allogeneic haematopoietic cell transplantation.
Autorzy:
Elias S; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Bone Marrow Transplantation and Cancer Immunotherapy, Faculty of Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel. Brown S; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Devlin SM; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA. BarkerJN; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Cho C; John Theurer Cancer Center, Hackensack University Medical Center, New Jersey, Hackensack, USA. Chung DJ; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Dahi PB; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Giralt S; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Gyurkocza B; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Jakubowski AA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Lahoud OB; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Landau H; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Lin RJ; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Papadopoulos EB; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Politikos I; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Ponce DM; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Scordo M; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Shaffer BC; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Shah GL; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Tamari R; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Young JW; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.; The Rockefeller University, New York, New York, USA. Perales MA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA. Shouval R; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.
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Źródło:
British journal of haematology [Br J Haematol] 2023 Dec; Vol. 203 (5), pp. 840-851. Date of Electronic Publication: 2023 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Real-World Implementation and Outcomes of Adalimumab Therapeutic Drug Monitoring in Psoriasis: A National Specialized Center Experience.
Autorzy:
Raharja A; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Arkir Z; Reference Chemistry, Synnovis, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom. Rinaldi G; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Tsakok T; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Dasandi T; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Guard S; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. McGuire A; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Pink AE; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Woolf R; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. BarkerJN; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Smith CH; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Mahil SK; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Electronic address: .
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