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Tytuł:
The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo
Autorzy:
Sychev DA
Ashraf GM
Svistunov AA
Maksimov ML
Tarasov VV
Chubarev VN
Otdelenov VA
Denisenko NP
Barreto GE
Aliev G
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Temat:
Cytochrome CYP-450
Drug interaction
Drug metabolism
Phenotyping
Therapeutics. Pharmacology
RM1-950
Źródło:
Drug Design, Development and Therapy, Vol Volume 12, Pp 1147-1156 (2018)
Opis pliku:
electronic resource
Relacje:
https://www.dovepress.com/the-cytochrome-p450-isoenzyme-and-some-new-opportunities-for-the-predi-peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881
Dostęp URL:
https://doaj.org/article/084a5e689b81484c82b063dd7653eb8c  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Repurposing of Tibolone in Alzheimer's Disease.
Autorzy:
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
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Źródło:
Biomolecules [Biomolecules] 2023 Jul 13; Vol. 13 (7). Date of Electronic Publication: 2023 Jul 13.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease*/metabolism
Neurodegenerative Diseases*/metabolism
Female ; Humans ; Drug Repositioning ; Amyloid beta-Peptides/metabolism ; Estrogens
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of Antioxidant Capacity and Network Pharmacology of Phloretin and Phlorizin against Neuroinflammation in Traumatic Brain Injury.
Autorzy:
Ongay KK; Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland.
Granato D; Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland.
Barreto GE; Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jan 17; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:
Meta-Analysis; Journal Article
MeSH Terms:
Antioxidants*/metabolism
Brain Injuries, Traumatic*/drug therapy
Humans ; Phloretin/pharmacology ; Phlorhizin/pharmacology ; Neuroinflammatory Diseases ; Network Pharmacology ; Iron
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lower calcium levels in hair of Parkinson's disease patients are associated with presence of sleeping disturbances.
Autorzy:
Dos Santos AB; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Departamento de Ciências e Tecnologias, Universidade Estadual do Sudoeste da Bahia, Bahia, Brazil.
Bezerra MA; Departamento de Ciências e Tecnologias, Universidade Estadual do Sudoeste da Bahia, Bahia, Brazil.
Rocha ME; Departamento de Ciências e Tecnologias, Universidade Estadual do Sudoeste da Bahia, Bahia, Brazil.
Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland.
Kohlmeier KA; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Nutritional neuroscience [Nutr Neurosci] 2022 Dec; Vol. 25 (12), pp. 2577-2587. Date of Electronic Publication: 2021 Oct 25.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/complications
Sleep Wake Disorders*
Disorders of Excessive Somnolence*/complications
Disorders of Excessive Somnolence*/epidemiology
Humans ; Calcium/analysis ; Hair/chemistry ; Zinc
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Respirasome Proteins Are Regulated by Sex-Hormone Interactions in the Brain.
Autorzy:
McGovern AJ; Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland.
Arevalo MA; Instituto Cajal, CSIC, 28002 Madrid, Spain.; CIBERFES, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Ciordia S; Unidad de Proteómica, Centro Nacional de Biotecnología (CNB-CSIC), Cantoblanco, 28049 Madrid, Spain.
Garcia-Segura LM; Instituto Cajal, CSIC, 28002 Madrid, Spain.; CIBERFES, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Barreto GE; Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 25; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 25.
Typ publikacji:
Journal Article
MeSH Terms:
Proteomics*
Mitochondrial Membranes*/metabolism
Animals ; Mice ; Female ; Male ; Gonadal Steroid Hormones/metabolism ; Brain/metabolism ; Proteins/metabolism ; Hormones/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
New Drug Design Avenues Targeting Alzheimer's Disease by Pharmacoinformatics-Aided Tools.
Autorzy:
Arrué L; Centro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca 3480094, Chile.
Cigna-Méndez A; Facultad de Ingeniería, Instituto de Ciencias Químicas Aplicadas, Universidad Autónoma de Chile, Santiago 8910060, Chile.
Barbosa T; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Borrego-Muñoz P; Escuela de Medicina, Fundación Universitaria Juan N. Corpas, Bogotá 110311, Colombia.
Struve-Villalobos S; Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Temuco 4780000, Chile.
Oviedo V; Facultad de Ingeniería, Instituto de Ciencias Químicas Aplicadas, Universidad Autónoma de Chile, Santiago 8910060, Chile.
Martínez-García C; Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, Bogotá 111321, Colombia.
Sepúlveda-Lara A; Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Temuco 4780000, Chile.
Millán N; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Márquez Montesinos JCE; Center for Bioinformatics, Simulation and Modeling (CBSM), Universidad de Talca, Talca 3460000, Chile.
Muñoz J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Santana PA; Facultad de Ingeniería, Instituto de Ciencias Químicas Aplicadas, Universidad Autónoma de Chile, Santiago 8910060, Chile.
Peña-Varas C; Departamento de Farmacología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción 4030000, Chile.
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
González J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Ramírez D; Departamento de Farmacología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción 4030000, Chile.
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Źródło:
Pharmaceutics [Pharmaceutics] 2022 Sep 09; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 09.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metabolomic Analysis of Human Astrocytes in Lipotoxic Condition: Potential Biomarker Identification by Machine Learning Modeling.
Autorzy:
Castellanos DB; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110311, Colombia.
Martín-Jiménez CA; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, GA 30329-4208, USA.
Pinzón A; Laboratorio de Bioinformática y Biología de Sistemas, Universidad Nacional de Colombia, Bogotá 111321, Colombia.
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Padilla-González GF; Royal Botanic Gardens, Kew, London TW9 3AE, UK.
Aristizábal A; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110311, Colombia.
Zuluaga M; Escuela de Ciencias Básicas Tecnologías e Ingenierías, Universidad Nacional Abierta y a Distancia, Dosquebradas 661001, Colombia.
González Santos J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110311, Colombia.
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Źródło:
Biomolecules [Biomolecules] 2022 Jul 15; Vol. 12 (7). Date of Electronic Publication: 2022 Jul 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes*/metabolism
Glutamic Acid*/metabolism
Biomarkers/metabolism ; Humans ; Machine Learning ; Obesity/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tibolone Pre-Treatment Ameliorates the Dysregulation of Protein Translation and Transport Generated by Palmitic Acid-Induced Lipotoxicity in Human Astrocytes: A Label-Free MS-Based Proteomics and Network Analysis.
Autorzy:
Vesga-Jiménez DJ; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Martín-Jiménez CA; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Grismaldo Rodríguez A; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota 110231, Colombia.
Aristizábal-Pachón AF; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota 110231, Colombia.
Pinzón A; Laboratorio de Bioinformática y Biología de Sistemas, Universidad Nacional de Colombia, Bogota 111321, Colombia.
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Ramírez D; Departamento de Farmacología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepcion 4030000, Chile.
González J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota 110231, Colombia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 09; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/metabolism
Palmitic Acid*/pharmacology
Fatty Acids/metabolism ; Humans ; Norpregnenes ; Protein Biosynthesis ; Proteomics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fatty Acids: An Insight into the Pathogenesis of Neurodegenerative Diseases and Therapeutic Potential.
Autorzy:
Vesga-Jiménez DJ; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota 110231, Colombia.; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Martin C; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.; Health Research Institute, University of Limerick, V94 T9PX Limerick, Ireland.
Aristizábal-Pachón AF; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota 110231, Colombia.
Pinzón A; Laboratorio de Bioinformática y Biología de Sistemas, Universidad Nacional de Colombia, Bogota 111321, Colombia.
González J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota 110231, Colombia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 25; Vol. 23 (5). Date of Electronic Publication: 2022 Feb 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Fatty Acids*/metabolism
Neurodegenerative Diseases*/etiology
Neurodegenerative Diseases*/therapy
Endoplasmic Reticulum Stress ; Humans ; Oleic Acid/pharmacology ; Palmitic Acid/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrated Metabolomics and Lipidomics Reveal High Accumulation of Glycerophospholipids in Human Astrocytes under the Lipotoxic Effect of Palmitic Acid and Tibolone Protection.
Autorzy:
Cabezas R; Grupo de Investigación en Ciencias Biomédicas GRINCIBIO, Facultad de Medicina, Universidad Antonio Nariño, Bogota 110231, Colombia.
Martin-Jiménez C; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, GA 30301, USA.
Zuluaga M; Escuela de Ciencias Básicas Tecnologías e Ingenierías, Universidad Nacional Abierta y a Distancia, Bogota 111511, Colombia.; Grupo de Investigación en Cromatografía y Técnicas Afines, Universidad de Caldas, Manizales 170002, Colombia.
Pinzón A; Laboratorio de Bioinformática y Biología de Sistemas, Universidad Nacional de Colombia-Bogotá, Bogota 111321, Colombia.
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.; Health Research Institute, University of Limerick, V94 T9PX Limerick, Ireland.
González J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana Bogotá, Bogota 110231, Colombia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 23; Vol. 23 (5). Date of Electronic Publication: 2022 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Lipidomics*
Palmitic Acid*/metabolism
Palmitic Acid*/toxicity
Astrocytes/metabolism ; Glycerophospholipids/metabolism ; Humans ; Metabolomics ; Norpregnenes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Emerging Role of Long Non-Coding RNAs and MicroRNAs in Neurodegenerative Diseases: A Perspective of Machine Learning.
Autorzy:
García-Fonseca Á; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Martin-Jimenez C; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Pachón AFA; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
González J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
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Źródło:
Biomolecules [Biomolecules] 2021 Jul 31; Vol. 11 (8). Date of Electronic Publication: 2021 Jul 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Machine Learning*
Alzheimer Disease/*genetics
Amyotrophic Lateral Sclerosis/*genetics
MicroRNAs/*genetics
Parkinson Disease/*genetics
RNA, Long Noncoding/*genetics
Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Computational Biology/methods ; Databases, Genetic ; Gene Expression Regulation ; Humans ; Information Dissemination ; Internet ; MicroRNAs/classification ; MicroRNAs/metabolism ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism ; Neurons/pathology ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; RNA, Long Noncoding/classification ; RNA, Long Noncoding/metabolism ; Signal Transduction ; Software
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Neuroglobin in the Neuroprotective Actions of Estradiol and Estrogenic Compounds.
Autorzy:
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
McGovern AJ; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Garcia-Segura LM; Instituto Cajal, Consejo Superior de Investigaciones Científicas (C.S.I.C.), 28002 Madrid, Spain.
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Źródło:
Cells [Cells] 2021 Jul 27; Vol. 10 (8). Date of Electronic Publication: 2021 Jul 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain/*drug effects
Brain Diseases/*drug therapy
Estradiol/*therapeutic use
Estrogens/*therapeutic use
Neuroglobin/*metabolism
Neurons/*drug effects
Neuroprotective Agents/*therapeutic use
Animals ; Brain/metabolism ; Brain/pathology ; Brain Diseases/metabolism ; Brain Diseases/pathology ; Estradiol/metabolism ; Female ; Humans ; Male ; Neurons/metabolism ; Neurons/pathology ; Sex Factors ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Curcumin: A small molecule with big functionality against amyloid aggregation in neurodegenerative diseases and type 2 diabetes.
Autorzy:
Radbakhsh S; Department of Medical Biotechnology and Nanotechnology, Mashhad University of Medical Sciences, Mashhad, Iran.
Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland.; Health Research Institute, University of Limerick, Limerick, Ireland.
Bland AR; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.; Department of Chemistry, University of Otago, Dunedin, New Zealand.
Sahebkar A; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło:
BioFactors (Oxford, England) [Biofactors] 2021 Jul; Vol. 47 (4), pp. 570-586. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alzheimer Disease/*drug therapy
Amyloidosis/*prevention & control
Creutzfeldt-Jakob Syndrome/*drug therapy
Curcumin/*therapeutic use
Diabetes Mellitus, Type 2/*drug therapy
Huntington Disease/*drug therapy
Neuroprotective Agents/*therapeutic use
Parkinson Disease/*drug therapy
Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/antagonists & inhibitors ; Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/metabolism ; Amyloidosis/genetics ; Amyloidosis/metabolism ; Amyloidosis/pathology ; Clinical Trials as Topic ; Creutzfeldt-Jakob Syndrome/genetics ; Creutzfeldt-Jakob Syndrome/metabolism ; Creutzfeldt-Jakob Syndrome/pathology ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Humans ; Huntington Disease/genetics ; Huntington Disease/metabolism ; Huntington Disease/pathology ; Hypoglycemic Agents/therapeutic use ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondria/pathology ; Oxidative Stress ; Parkinson Disease/genetics ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; Protein Aggregates/drug effects ; alpha-Synuclein/antagonists & inhibitors ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism ; tau Proteins/antagonists & inhibitors ; tau Proteins/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Neural Stem Cell-Based Therapies and Glioblastoma Management: Current Evidence and Clinical Challenges.
Autorzy:
Benmelouka AY; Faculty of Medicine, University of Algiers, Algiers 16000, Algeria.
Munir M; Faculty of Medicine, Ain Shams University, Cairo 11591, Egypt.
Sayed A; Faculty of Medicine, Ain Shams University, Cairo 11591, Egypt.
Attia MS; Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Ali MM; Faculty of Medicine, Al-Azhar University, Damietta 34511, Egypt.
Negida A; School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2UP, UK.; Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.
Alghamdi BS; Department of Physiology, Neuroscience Unit, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Pre-Clinical Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Kamal MA; West China School of Nursing/Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.; King Fahd Medical Research Center, King Abdulaziz University, P. O. Box 80216, Jeddah 21589, Saudi Arabia.; Novel Global Community Educational Foundation, 7 Peterlee Place, Hebersham, NSW 2770, Australia.
Barreto GE; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.; Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Santiago 32310, Chile.
Ashraf GM; Pre-Clinical Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Meshref M; MSc Neurology, Al-Azhar University, Cairo 11651, Egypt.
Bahbah EI; Faculty of Medicine, Al-Azhar University, Damietta 34511, Egypt.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 24; Vol. 22 (5). Date of Electronic Publication: 2021 Feb 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain Neoplasms/*therapy
Glioblastoma/*therapy
Neural Stem Cells/*cytology
Stem Cell Transplantation/*methods
Animals ; Disease Management ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Epigenetic aspects of multiple sclerosis and future therapeutic options.
Autorzy:
Jamebozorgi K; Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran.
Rostami D; School of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, Iran.
Pormasoumi H; Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran.
Taghizadeh E; Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.; Department of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland.; Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Santiago, Chile.
Sahebkar A; Halal Research Center of IRI, FDA, Tehran, Iran.; Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło:
The International journal of neuroscience [Int J Neurosci] 2021 Jan; Vol. 131 (1), pp. 56-64. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Epigenesis, Genetic/*genetics
Multiple Sclerosis, Chronic Progressive/*genetics
Multiple Sclerosis, Chronic Progressive/*therapy
Multiple Sclerosis, Relapsing-Remitting/*genetics
Multiple Sclerosis, Relapsing-Remitting/*therapy
DNA Methylation/genetics ; Forecasting ; Genetic Therapy/trends ; Humans ; MicroRNAs/genetics ; Multiple Sclerosis/diagnosis ; Multiple Sclerosis/genetics ; Multiple Sclerosis/therapy ; Multiple Sclerosis, Chronic Progressive/diagnosis ; Multiple Sclerosis, Relapsing-Remitting/diagnosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tibolone Ameliorates the Lipotoxic Effect of Palmitic Acid in Normal Human Astrocytes.
Autorzy:
Martin-Jiménez C; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia. .
González J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia. .
Vesga D; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
Aristizabal A; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland.; Health Research Institute, University of Limerick, Limerick, Ireland.
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Źródło:
Neurotoxicity research [Neurotox Res] 2020 Oct; Vol. 38 (3), pp. 585-595. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes/*drug effects
Neurons/*drug effects
Norpregnenes/*pharmacology
Palmitic Acid/*pharmacology
Cell Line ; Cell Survival/drug effects ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Palmitic Acid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review.
Autorzy:
Bagheri H; Department of Biotechnology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
Ghasemi F; Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland.; Health Research Institute, University of Limerick, Limerick, Ireland.
Sathyapalan T; Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, UK.
Jamialahmadi T; Halal Research Center of IRI, FDA, Tehran, Iran.; Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Sahebkar A; Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło:
BioFactors (Oxford, England) [Biofactors] 2020 May; Vol. 46 (3), pp. 309-325. Date of Electronic Publication: 2019 Dec 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology
Microglia/*drug effects
Neurodegenerative Diseases/*prevention & control
Neuroprotective Agents/*pharmacology
Animals ; Disease Models, Animal ; Humans ; Mice ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Scientific productivity in neurosciences in Latin America: a scientometrics perspective.
Autorzy:
Forero DA; Laboratory of NeuroPsychiatric Genetics, Biomedical Sciences Research Group, School of Medicine, Universidad Antonio Nariño, Bogotá, Colombia.; PhD Program in Health Sciences, School of Medicine, Universidad Antonio Nariño, Bogotá, Colombia.
Trujillo ML; School of Sciences, Universidad Antonio Nariño, Bogotá, Colombia.
González-Giraldo Y; Center for Psychosocial Studies for Latin America and the Caribbean, School of Psychosocial Therapies, Universidad Antonio Nariño, Bogotá, Colombia.
Barreto GE; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia.
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Źródło:
The International journal of neuroscience [Int J Neurosci] 2020 Apr; Vol. 130 (4), pp. 398-406. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Bibliometrics*
Neurosciences/*statistics & numerical data
Periodicals as Topic/*statistics & numerical data
Biomedical Research/statistics & numerical data ; Humans ; Latin America ; Peer Review, Research
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins.
Autorzy:
Chamani S; Birjand University of Medical Sciences, Birjand, Iran.
Bianconi V; Unit of Internal Medicine, Department of Medicine, University of Perugia, Perugia, Italy.
Tasbandi A; School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Pirro M; Unit of Internal Medicine, Department of Medicine, University of Perugia, Perugia, Italy.
Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland.; Health Research Institute, University of Limerick, Limerick, Ireland.
Jamialahmadi T; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Department of Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Sahebkar A; Halal Research Center of IRI, FDA, Tehran, Iran.; Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło:
Mediators of inflammation [Mediators Inflamm] 2020 Mar 25; Vol. 2020, pp. 3267172. Date of Electronic Publication: 2020 Mar 25 (Print Publication: 2020).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Inflammation/*metabolism
Neurodegenerative Diseases/*immunology
Neurodegenerative Diseases/*metabolism
Animals ; Docosahexaenoic Acids/metabolism ; Eicosapentaenoic Acid/metabolism ; Humans ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 49

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