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    Wyświetlanie 1-13 z 13
    Podgląd okładki
    Tytuł :
    Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition.
    Autorzy :
    Maezawa S; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. .; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. .; Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, Japan. .; Faculty of Science and Technology, Department of Applied Biological Science, Tokyo University of Science, Noda, Chiba, Japan. .
    Sakashita A; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Molecular Biology, Keio University School of Medicine, Tokyo, Japan.
    Yukawa M; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
    Chen X; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
    Takahashi K; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Alavattam KG; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Nakata I; Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, Japan.
    Weirauch MT; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
    Barski A; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
    Namekawa SH; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. .; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. .; Department of Microbiology and Molecular Genetics, University of California, Davis, Davis, CA, USA. .
    Pokaż więcej
    Źródło :
    Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Oct; Vol. 27 (10), pp. 978-988. Date of Electronic Publication: 2020 Sep 07.
    Typ publikacji :
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms :
    Enhancer Elements, Genetic*
    Meiosis/*genetics
    Mitosis/*genetics
    Polycomb-Group Proteins/*genetics
    Proto-Oncogene Proteins c-myb/*genetics
    Spermatogenesis/*genetics
    Trans-Activators/*genetics
    Animals ; Cell Differentiation ; Gene Expression Regulation ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Mutation ; Polycomb-Group Proteins/metabolism ; Proto-Oncogene Proteins c-myb/metabolism ; Spermatogonia/cytology ; Spermatogonia/physiology ; Trans-Activators/metabolism ; X Chromosome/genetics
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development.
    Autorzy :
    Alavattam KG; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Maezawa S; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, Japan.
    Sakashita A; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Khoury H; Department of Physiology, Biophysics & Systems Biology, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
    Barski A; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
    Kaplan N; Department of Physiology, Biophysics & Systems Biology, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel. .
    Namekawa SH; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. .; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. .
    Pokaż więcej
    Źródło :
    Nature structural & molecular biology [Nat Struct Mol Biol] 2019 Mar; Vol. 26 (3), pp. 175-184. Date of Electronic Publication: 2019 Feb 18.
    Typ publikacji :
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms :
    Chromatin Assembly and Disassembly/*physiology
    Meiosis/*physiology
    Spermatids/*growth & development
    Spermatocytes/*growth & development
    Spermatogenesis/*physiology
    Animals ; Chromatin/metabolism ; Chromosomes/metabolism ; Interphase/physiology ; Male ; Meiotic Prophase I/physiology ; Mice ; Mice, Inbred C57BL ; Protein Domains/physiology
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline.
    Autorzy :
    Sin HS; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 49229, USA.; Present address: Department of Developmental Biology, Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305, USA.
    Kartashov AV; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 49229, USA.
    Hasegawa K; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 49229, USA.; Present address: Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
    Barski A; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA. artem.barski@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 49229, USA. artem.barski@cchmc.org.
    Namekawa SH; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA. .; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 49229, USA. .
    Pokaż więcej
    Źródło :
    BMC biology [BMC Biol] 2015 Jul 22; Vol. 13, pp. 53. Date of Electronic Publication: 2015 Jul 22.
    Typ publikacji :
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms :
    Epigenesis, Genetic*
    Meiosis*
    Mitosis*
    Spermatogenesis*
    Chromatin/*genetics
    Germ Cells/*cytology
    Sex Chromosomes/*genetics
    Animals ; Cells, Cultured ; Chromatin/chemistry ; Gene Expression Regulation, Developmental ; Genes, X-Linked ; Germ Cells/metabolism ; Histones/chemistry ; Histones/genetics ; Male ; Mice, Inbred C57BL ; Sex Chromosomes/chemistry ; Transcriptional Activation ; Transcriptome ; X Chromosome Inactivation
    Czasopismo naukowe
    Szczegóły Pełny tekst
    Podgląd okładki
    Tytuł :
    RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids.
    Autorzy :
    Sin HS; Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 45229, USA.
    Barski A
    Zhang F
    Kartashov AV
    Nussenzweig A
    Chen J
    Andreassen PR
    Namekawa SH
    Pokaż więcej
    Źródło :
    Genes & development [Genes Dev] 2012 Dec 15; Vol. 26 (24), pp. 2737-48.
    Typ publikacji :
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms :
    Epigenomics*
    Meiosis*
    Transcriptional Activation*
    Sex Chromosomes/*metabolism
    Ubiquitin-Protein Ligases/*metabolism
    Animals ; Cell Line, Tumor ; Histones/metabolism ; Humans ; Male ; Nucleic Acid Conformation ; Protamines/metabolism ; Spermatids/metabolism ; Spermatocytes/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination ; X Chromosome Inactivation/genetics
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline
    Autorzy :
    Maezawa So
    Hasegawa Kazuteru
    Yukawa Masashi
    Kubo Naoki
    Sakashita Akihiko
    Alavattam Kris G.
    Sin Ho-Su
    Kartashov Andrey V.
    Sasaki Hiroyuki
    Barski Artem
    Namekawa Satoshi H.
    Pokaż więcej
    Źródło :
    Proceedings of the National Academy of Sciences of the United States of America. 115(19):4957-4962
    Dostęp URL :
    https://www.jstor.org/stable/26509583
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline.
    Autorzy :
    So Maezawa
    Kazuteru Hasegawa
    Masashi Yukawa
    Naoki Kubo
    Akihiko Sakashita
    Alavattam, Kris G.
    Ho-Su Sin
    Kartashov, Andrey V.
    Hiroyuki Sasaki
    Barski, Artem
    Satoshi H. Namekawa
    Pokaż więcej
    Temat :
    CHROMATIN
    GERM cells
    POLYCOMB group proteins
    SPERMATOGENESIS
    LABORATORY mice
    Źródło :
    Proceedings of the National Academy of Sciences of the United States of America; 5/8/2018, Vol. 115 Issue 19, p4957-4962, 6p
    Czasopismo naukowe
    Szczegóły
    Podgląd okładki
    Tytuł :
    RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes.
    Autorzy :
    Adams, Shannel R.
    Maezawa, So
    Alavattam, Kris G.
    Abe, Hironori
    Sakashita, Akihiko
    Shroder, Megan
    Broering, Tyler J.
    Sroga Rios, Julie
    Thomas, Michael A.
    Lin, Xinhua
    Price, Carolyn M.
    Barski, Artem
    Andreassen, Paul R.
    Namekawa, Satoshi H.
    Pokaż więcej
    Temat :
    SEX chromosomes
    GENETIC regulation
    UBIQUITINATION
    ACETYLATION
    GERM cells
    SPERMATOGENESIS
    Źródło :
    PLoS Genetics; 2/20/2018, Vol. 14 Issue 2, p1-26, 26p
    Czasopismo naukowe
    Szczegóły Pełny tekst Pełny tekst
    Podgląd okładki
    Tytuł :
    Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline.
    Autorzy :
    Ho-Su Sin
    Kartashov, Andrey V.
    Hasegawa, Kazuteru
    Barski, Artem
    Namekawa, Satoshi H.
    Pokaż więcej
    Temat :
    FUNGAL chromatin
    GERM cells
    MEIOSIS
    SPERMATOGENESIS
    GENETIC sex determination
    EMBRYONIC stem cells
    SEX differentiation (Embryology)
    FUNGI
    Źródło :
    BMC Biology; Jul2015, Vol. 13 Issue 1, p1-15, 15p
    Czasopismo naukowe
    Szczegóły Pełny tekst
      Wyświetlanie 1-13 z 13

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