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Wyświetlanie 1-11 z 11
Tytuł :
Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer.
Autorzy :
Kocakavuk E; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; DKFZ Division of Translational Neurooncology at the West German Cancer Center, German Cancer Consortium Partner Site, University Hospital Essen, Essen, Germany.; Department of Neurosurgery, University Hospital Essen, Essen, Germany.
Anderson KJ; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Varn FS; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Johnson KC; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Amin SB; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Sulman EP; NYU Langone Health, New York, NY, USA.
Lolkema MP; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. .; Department of Pathology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. .; Cancer and Cell Biology Division, The Translational Genomics Research Institute, Phoenix, AZ, USA. .
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. .
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Źródło :
Nature genetics [Nat Genet] 2021 Jul; Vol. 53 (7), pp. 1088-1096. Date of Electronic Publication: 2021 May 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neoplasms/*genetics
Neoplasms/*mortality
Radiotherapy/*adverse effects
Sequence Deletion/*radiation effects
DNA Damage/radiation effects ; Humans ; Mutagenesis/radiation effects ; Neoplasm Recurrence, Local ; Neoplasms/epidemiology ; Neoplasms/radiotherapy ; Prognosis ; Radiation, Ionizing
Czasopismo naukowe
Tytuł :
Spatial concordance of DNA methylation classification in diffuse glioma.
Autorzy :
Verburg N; Department of Neurosurgery, Amsterdam UMC, Vrije Universiteit, and Brain Tumor Centre, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Cambridge Brain Tumor Imaging Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Hill Rd, Cambridge CB2 0QQ, UK.
Barthel FP; The Jackson Laboratory For Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.
Anderson KJ; The Jackson Laboratory For Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.
Johnson KC; The Jackson Laboratory For Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.
Koopman T; Department of Radiology & Nuclear Medicine, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Yaqub MM; Department of Radiology & Nuclear Medicine, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Hoekstra OS; Department of Radiology & Nuclear Medicine, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Lammertsma AA; Department of Radiology & Nuclear Medicine, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Barkhof F; Department of Radiology & Nuclear Medicine, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; UCL institutes of Neurology & Healthcare Engineering, Gower St, Bloomsbury, London WC1E 6BT, United Kingdom.
Pouwels PJW; Department of Radiology & Nuclear Medicine, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Reijneveld JC; Department of Neurology, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Department of Neurology, Stichting Epilepsie Instellingen Nederland, Heemstede, The Netherlands.
Rozemuller AJM; Department of Pathology, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Beliën JAM; Department of Pathology, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Boellaard R; Department of Radiology & Nuclear Medicine, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Taylor MD; Department of Neurosurgery, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada.; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Kids, Toronto, Ontario Canada.
Das S; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Kids, Toronto, Ontario Canada.; Division of Neurosurgery, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ontario Canada.
Costello JF; Department of Neurological Surgery, UCSF, 505 Parnassus Ave, San Francisco, CA 94143, USA.
Vandertop WP; Department of Neurosurgery, Amsterdam UMC, Vrije Universiteit, and Brain Tumor Centre, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Wesseling P; Department of Pathology, Amsterdam UMC, location VUmc, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; Princess Máxima Centre for Paediatric Oncology, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
de Witt Hamer PC; Department of Neurosurgery, Amsterdam UMC, Vrije Universiteit, and Brain Tumor Centre, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Verhaak RGW; Department of Neurosurgery, Amsterdam UMC, Vrije Universiteit, and Brain Tumor Centre, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.; The Jackson Laboratory For Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.
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Źródło :
Neuro-oncology [Neuro Oncol] 2021 May 28. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.
Autorzy :
Wen PY; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Weller M; Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.
Lee EQ; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Alexander BM; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Barnholtz-Sloan JS; Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, USA.
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Batchelor TT; Department of Neurology, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School.
Bindra RS; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, USA.
Chang SM; University of California San Francisco, San Francisco, California, USA.
Chiocca EA; Department of Neurosurgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.
Cloughesy TF; David Geffen School of Medicine, Department of Neurology, University of California Los Angeles, Los Angeles, California, USA.
DeGroot JF; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Galanis E; Mayo Clinic, Rochester, Minnesota, USA.
Gilbert MR; Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Hegi ME; Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Horbinski C; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Huang RY; Division of Neuroradiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Lassman AB; Department of Neurology and Herbert Irving Comprehensive Cancer Center, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York, USA.
Le Rhun E; University of Lille, Inserm, Neuro-oncology, General and Stereotaxic Neurosurgery service, University Hospital of Lille, Lille, France; Breast Cancer Department, Oscar Lambret Center, Lille, France and Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.
Lim M; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Mehta MP; Miami Cancer Institute, Miami, Florida, USA.
Mellinghoff IK; Department of Neurology and Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Minniti G; Radiation Oncology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
Nathanson D; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, USA.
Platten M; Department of Neurology, Medical Faculty Mannheim, MCTN, Heidelberg University, Heidelberg, Germany.
Preusser M; Division of Oncology, Department of Medicine, Medical University of Vienna, Vienna, Austria.
Roth P; Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.
Sanson M; Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, Paris, France.
Schiff D; University of Virginia School of Medicine, Division of Neuro-Oncology, Department of Neurology, University of Virginia, Charlottesville, Virginia, USA.
Short SC; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Taphoorn MJB; Department of Neurology, Medical Center Haaglanden, The Hague and Department of Neurology, Leiden University Medical Center, the Netherlands.
Tonn JC; Department of Neurosurgery, University Hospital, LMU Munich, Munich, Germany.
Tsang J; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, USA.
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
von Deimling A; Neuropathology and Clinical Cooperation Unit Neuropathology, University Heidelberg and German Cancer Center, Heidelberg, Germany.
Wick W; Department of Neurology and Neuro-oncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
Zadeh G; MacFeeters Hamilton Centre for Neuro-Oncology Research, Princess Margaret Cancer Centre, Toronto, Canada.
Reardon DA; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Aldape KD; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
van den Bent MJ; Department of Neurology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
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Źródło :
Neuro-oncology [Neuro Oncol] 2020 Aug 17; Vol. 22 (8), pp. 1073-1113.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain Neoplasms*/enzymology
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Glioblastoma*/enzymology
Glioblastoma*/genetics
Glioblastoma*/therapy
Chemoradiotherapy ; Clinical Trials, Phase III as Topic ; Consensus ; Humans ; Isocitrate Dehydrogenase/genetics ; Isocitrate Dehydrogenase/metabolism ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Comparative Molecular Life History of Spontaneous Canine and Human Gliomas.
Autorzy :
Amin SB; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Anderson KJ; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Boudreau CE; Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Martinez-Ledesma E; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Avenue Morones Prieto 3000, Monterrey, Nuevo Leon 64710, Mexico; Department of Neuro-Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kocakavuk E; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA; DKFZ Division of Translational Neurooncology at the West German Cancer Center (WTZ), German Cancer Consortium (DKTK) Partner Site & Department of Neurosurgery, University Hospital Essen, Essen, Germany.
Johnson KC; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Varn FS; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Kassab C; Department of Neurosurgery, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Ling X; Department of Neurosurgery, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kim H; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Barter M; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Lau CC; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA; Connecticut Children's Medical Center, Hartford, CT 06106, USA; University of Connecticut School of Medicine, Farmington, CT 06032, USA.
Ngan CY; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Chapman M; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Koehler JW; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
Long JP; Department of Neurosurgery, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Biostatistics, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Miller AD; Department of Biomedical Sciences, Section of Anatomic Pathology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Miller CR; Departments of Pathology and Laboratory Medicine, Neurology, and Pharmacology, Lineberger Comprehensive Cancer Center and Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Porter BF; Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Rissi DR; Department of Pathology and Athens Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Mazcko C; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
LeBlanc AK; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Dickinson PJ; Department of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, Davis, CA, USA.
Packer RA; Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Taylor AR; Auburn University College of Veterinary Medicine, Auburn, AL, USA.
Rossmeisl JH Jr; VA-MD College of Veterinary Medicine, Blacksburg, VA, USA.
Woolard KD; Department of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, Davis, CA, USA.
Heimberger AB; Department of Neurosurgery, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Levine JM; Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Feb 10; Vol. 37 (2), pp. 243-257.e7.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms/*genetics
DNA Methylation/*genetics
Glioma/*genetics
Mutation/*genetics
Animals ; Dogs ; Exome/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł :
Molecular and clonal evolution in recurrent metastatic gliosarcoma.
Autorzy :
Anderson KJ; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06085, USA.
Tan AC; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.; National Cancer Centre Singapore, Singapore, 169610 Singapore.
Parkinson J; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.; The Brain Cancer Group, North Shore Private Hospital, St Leonards, New South Wales 2065, Australia.; The NHMRC Clinical Trials Centre, the University of Sydney, Camperdown, New South Wales 2066, Australia.
Back M; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.; The Brain Cancer Group, North Shore Private Hospital, St Leonards, New South Wales 2065, Australia.; The NHMRC Clinical Trials Centre, the University of Sydney, Camperdown, New South Wales 2066, Australia.
Kastelan M; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.; The Brain Cancer Group, North Shore Private Hospital, St Leonards, New South Wales 2065, Australia.
Newey A; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.
Brewer J; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.
Wheeler H; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.; The Brain Cancer Group, North Shore Private Hospital, St Leonards, New South Wales 2065, Australia.; The NHMRC Clinical Trials Centre, the University of Sydney, Camperdown, New South Wales 2066, Australia.; Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research, St Leonards, New South Wales 2065, Australia.
Hudson AL; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.; The Brain Cancer Group, North Shore Private Hospital, St Leonards, New South Wales 2065, Australia.; The NHMRC Clinical Trials Centre, the University of Sydney, Camperdown, New South Wales 2066, Australia.; Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research, St Leonards, New South Wales 2065, Australia.
Amin SB; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06085, USA.
Johnson KC; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06085, USA.
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06085, USA.; Department of Pathology, VU University Medical Center/Brain Tumor Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06085, USA.
Khasraw M; Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales 2065, Australia.; The Brain Cancer Group, North Shore Private Hospital, St Leonards, New South Wales 2065, Australia.; The NHMRC Clinical Trials Centre, the University of Sydney, Camperdown, New South Wales 2066, Australia.
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Źródło :
Cold Spring Harbor molecular case studies [Cold Spring Harb Mol Case Stud] 2020 Feb 03; Vol. 6 (1). Date of Electronic Publication: 2020 Feb 03 (Print Publication: 2020).
Typ publikacji :
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Transformation, Neoplastic/*genetics
Clonal Evolution/*genetics
Gliosarcoma/*etiology
Gliosarcoma/*pathology
Adult ; Alleles ; Biomarkers, Tumor ; Biopsy ; Combined Modality Therapy ; DNA Copy Number Variations ; Female ; Gliosarcoma/therapy ; Humans ; Immunohistochemistry ; Multimodal Imaging/methods ; Mutation ; Neoplasm Metastasis ; Neoplasm Staging ; Recurrence
Czasopismo naukowe
Tytuł :
Longitudinal molecular trajectories of diffuse glioma in adults.
Autorzy :
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Pathology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Johnson KC; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Varn FS; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Moskalik AD; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Tanner G; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Kocakavuk E; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; DKFZ Division of Translational Neurooncology at the West German Cancer Center, German Cancer Consortium Partner Site, University Hospital Essen, Essen, Germany.; Department of Neurosurgery, University Hospital Essen, Essen, Germany.
Anderson KJ; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Abiola O; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Aldape K; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Alfaro KD; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Alpar D; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Amin SB; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Ashley DM; Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, NC, USA.
Bandopadhayay P; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.
Barnholtz-Sloan JS; Department of Population and Quantitative Health Sciences, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Beroukhim R; Broad Institute, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Brastianos PK; Division of Neuro-Oncology, Massachusetts General Hospital, Boston, MA, USA.
Brat DJ; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Brodbelt AR; Department of Neurosurgery, University of Liverpool & Walton Centre NHS Trust, Liverpool, UK.
Bruns AF; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Bulsara KR; Division of Neurosurgery, The University of Connecticut Health Center, Farmington, CT, USA.
Chakrabarty A; Department of Cellular and Molecular Pathology, Leeds Teaching Hospital NHS Trust, St James's University Hospital, Leeds, UK.
Chakravarti A; Department of Radiation Oncology, The Ohio State Comprehensive Cancer Center-Arthur G. James Cancer Hospital, Columbus, OH, USA.
Chuang JH; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA.
Claus EB; Yale University School of Public Health, New Haven, CT, USA.; Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, USA.
Cochran EJ; Department of Pathology & Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Connelly J; Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Costello JF; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
Finocchiaro G; Fondazione IRCCS Istituto Neurologico Besta, Milano, Italy.
Fletcher MN; Division of Molecular Genetics, Heidelberg Center for Personalized Oncology, German Cancer Research Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany.
French PJ; Department of Neurology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.
Gan HK; Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Victoria, Australia.; La Trobe University School of Cancer Medicine, Heidelberg, Victoria, Australia.
Gilbert MR; Neuro-Oncology Branch, National Institutes of Health, Bethesda, MD, USA.
Gould PV; Anatomic Pathology Service, Hôpital de l'Enfant-Jésus, CHU de Québec-Université Laval, Quebec, Quebec, Canada.
Grimmer MR; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
Iavarone A; Department of Neurology, Columbia University Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.; Institute for Cancer Genetics, Columbia University Medical Center, New York, NY, USA.
Ismail A; Department of Cellular and Molecular Pathology, Leeds Teaching Hospital NHS Trust, St James's University Hospital, Leeds, UK.
Jenkinson MD; Department of Neurosurgery, University of Liverpool & Walton Centre NHS Trust, Liverpool, UK.
Khasraw M; Cooperative Trials Group for Neuro-Oncology (COGNO) NHMRC Clinical Trials Centre, The University of Sydney, Sydney, New South Wales, Australia.
Kim H; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Kouwenhoven MCM; Department of Neurology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
LaViolette PS; Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Li M; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Lichter P; Division of Molecular Genetics, Heidelberg Center for Personalized Oncology, German Cancer Research Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ligon KL; Broad Institute, Cambridge, MA, USA.; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.
Lowman AK; Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Malta TM; Department of Neurosurgery, Henry Ford Health System, Henry Ford Cancer Institute, Detroit, MI, USA.
Mazor T; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
McDonald KL; Cure Brain Cancer Biomarkers and Translational Research Group, Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
Molinaro AM; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
Nam DH; Department of Neurosurgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea.; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea.
Nayyar N; Division of Neuro-Oncology, Massachusetts General Hospital, Boston, MA, USA.
Ng HK; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.
Ngan CY; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Niclou SP; Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.
Niers JM; Department of Neurology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Noushmehr H; Department of Neurosurgery, Henry Ford Health System, Henry Ford Cancer Institute, Detroit, MI, USA.
Noorbakhsh J; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Ormond DR; Department of Neurosurgery, University of Colorado School of Medicine, Aurora, CO, USA.
Park CK; Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
Poisson LM; Department of Public Health Sciences, Henry Ford Health System, Henry Ford Cancer Institute, Detroit, MI, USA.
Rabadan R; Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, USA.; Department of Systems Biology, Columbia University, New York, NY, USA.
Radlwimmer B; Division of Molecular Genetics, Heidelberg Center for Personalized Oncology, German Cancer Research Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Rao G; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Reifenberger G; Institute of Neuropathology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Sa JK; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea.
Schuster M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Shaw BL; Division of Neuro-Oncology, Massachusetts General Hospital, Boston, MA, USA.
Short SC; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Smitt PAS; Department of Neurology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.
Sloan AE; Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA.; Department of Neurosurgery, Case Western Reserve University, Cleveland, OH, USA.; Seidman Cancer Center and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
Smits M; Department of Radiology & Nuclear Medicine, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.
Suzuki H; The Hospital for Sick Children, Toronto, ON, Canada.
Tabatabai G; Interdiscplinary Division of Neuro-Oncology, Hertie Institute for Clinical Brain Research, DKTK Partner Site Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.
Van Meir EG; Department of Neurosurgery, School of Medicine and Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Watts C; Institute of Cancer Genome Sciences, Department of Neurosurgery, University of Birmingham, Birmingham, UK.
Weller M; Department of Neurology, University Hospital Zurich, Zurich, Switzerland.
Wesseling P; Department of Pathology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Westerman BA; Department of Neurosurgery, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Widhalm G; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Woehrer A; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
Yung WKA; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zadeh G; Division of Neurosurgery, Department of Surgery, University Health Network, Toronto, Ontario, Canada.
Huse JT; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
De Groot JF; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Stead LF; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. .
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Corporate Authors :
GLASS Consortium
Źródło :
Nature [Nature] 2019 Dec; Vol. 576 (7785), pp. 112-120. Date of Electronic Publication: 2019 Nov 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioma/*genetics
Adult ; Chromosomes, Human, Pair 1 ; Chromosomes, Human, Pair 19 ; Disease Progression ; Glioma/pathology ; Humans ; Isocitrate Dehydrogenase/genetics ; Mutation ; Polymorphism, Single Nucleotide ; Recurrence
Czasopismo naukowe
Tytuł :
The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations.
Autorzy :
Menghi F; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
Yadav V; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
Tang M; MD Anderson Cancer Center, Houston, TX 77030, USA.
Ji B; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Tang Z; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
Carter GW; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Ruan Y; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
Scully R; Division of Hematology Oncology, Department of Medicine, and Cancer Research Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
Jonkers J; Oncode Institute and Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam 1066CX, the Netherlands.
Liu ET; The Jackson Laboratory, Bar Harbor, ME 04609, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2018 Aug 13; Vol. 34 (2), pp. 197-210.e5. Date of Electronic Publication: 2018 Jul 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Duplication*
Genomic Instability*
Mutation*
Tandem Repeat Sequences*
Neoplasms/*genetics
Animals ; Cyclin E/genetics ; Female ; Genes, BRCA1 ; Genes, p53 ; Humans ; Mice ; Oncogene Proteins/genetics ; Phenotype ; Triple Negative Breast Neoplasms/genetics ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Evolving Insights into the Molecular Neuropathology of Diffuse Gliomas in Adults.
Autorzy :
Barthel FP; Department of Pathology, VU University Medical Center, Brain Tumor Center Amsterdam, De Boelelaan 1117, Amsterdam 1081 HV, The Netherlands; The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.
Johnson KC; The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.
Wesseling P; Department of Pathology, VU University Medical Center, Brain Tumor Center Amsterdam, De Boelelaan 1117, Amsterdam 1081 HV, The Netherlands; Department of Pathology, Princess Máxima Center for Pediatric Oncology and University Medical Center Utrecht, Lundlaan 6, 3584 EA Utrecht, The Netherlands. Electronic address: .
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA. Electronic address: .
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Źródło :
Neurologic clinics [Neurol Clin] 2018 Aug; Vol. 36 (3), pp. 421-437.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Brain Neoplasms/*classification
Brain Neoplasms/*genetics
Brain Neoplasms/*pathology
Humans ; Neuropathology
Czasopismo naukowe
Tytuł :
Reconstructing the molecular life history of gliomas.
Autorzy :
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06030, USA. floris.barthel@gmail.com.; Department of Pathology, VU University Medical Center/Brain Tumor Center Amsterdam, Amsterdam, The Netherlands. floris.barthel@gmail.com.
Wesseling P; Department of Pathology, VU University Medical Center/Brain Tumor Center Amsterdam, Amsterdam, The Netherlands.; Department of Pathology, Princess Máxima Center for Pediatric Oncology and University Medical Center Utrecht, Utrecht, The Netherlands.
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06030, USA.
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Źródło :
Acta neuropathologica [Acta Neuropathol] 2018 May; Vol. 135 (5), pp. 649-670. Date of Electronic Publication: 2018 Apr 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Central Nervous System Neoplasms/*metabolism
Glioma/*metabolism
Animals ; Disease Progression ; Humans
Czasopismo naukowe
Tytuł :
Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Autorzy :
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Oncology Graduate School Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Wei W; Department of Biostatistics, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Tang M; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Martinez-Ledesma E; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Neuro-Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Hu X; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Program in Biostatistics, Bioinformatics, and Systems Biology, the University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas, USA.
Amin SB; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, USA.
Akdemir KC; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Seth S; Institute for Applied Cancer Science, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Song X; Institute for Applied Cancer Science, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Wang Q; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Lichtenberg T; Biopathology Center, Nationwide Children's Hospital, Columbus, Ohio, USA.
Hu J; Department of Cancer Biology, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Zhang J; Institute for Applied Cancer Science, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Zheng S; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Neuro-Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Verhaak RG; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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Źródło :
Nature genetics [Nat Genet] 2017 Mar; Vol. 49 (3), pp. 349-357. Date of Electronic Publication: 2017 Jan 30.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasms/*genetics
Point Mutation/*genetics
Telomere/*genetics
DNA Methylation/genetics ; Glioma/genetics ; Humans ; Promoter Regions, Genetic/genetics ; Retinoblastoma Binding Proteins/genetics ; Sarcoma/genetics ; Telomerase/genetics ; Tumor Suppressor Protein p53/genetics ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
Autorzy :
Ceccarelli M; Qatar Computing Research Institute, Hamad Bin Khalifa University, Doha P.O. box 5825, Qatar; Department of Science and Technology, University of Sannio, Benevento 82100, Italy.
Barthel FP; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Oncology Graduate School Amsterdam, Department of Pathology, VU University Medical Center, 1081 HV Amsterdam, the Netherlands.
Malta TM; Department of Genetics (CISBi/NAP), Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Monte Alegre, Ribeirão Preto-SP CEP: 14049-900, Brazil; Center for Integrative Systems Biology (CISBi, NAP/USP), Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14049-900, Brazil.
Sabedot TS; Department of Genetics (CISBi/NAP), Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Monte Alegre, Ribeirão Preto-SP CEP: 14049-900, Brazil; Center for Integrative Systems Biology (CISBi, NAP/USP), Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14049-900, Brazil.
Salama SR; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Murray BA; The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA.
Morozova O; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Newton Y; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Radenbaugh A; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Pagnotta SM; Department of Science and Technology, University of Sannio, Benevento 82100, Italy; BIOGEM Istituto di Ricerche Genetiche 'G. Salvatore,' Campo Reale, 83031 Ariano Irpino, Italy.
Anjum S; Qatar Computing Research Institute, Hamad Bin Khalifa University, Doha P.O. box 5825, Qatar.
Wang J; Department of Neurology, Department of Pathology, Institute for Cancer Genetics, Department of Systems Biology and Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA.
Manyam G; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Zoppoli P; Department of Neurology, Department of Pathology, Institute for Cancer Genetics, Department of Systems Biology and Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA.
Ling S; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rao AA; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Grifford M; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Cherniack AD; The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA.
Zhang H; The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA.
Poisson L; Henry Ford Hospital, Detroit, MI 48202, USA.
Carlotti CG Jr; Department of Genetics (CISBi/NAP), Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Monte Alegre, Ribeirão Preto-SP CEP: 14049-900, Brazil; Center for Integrative Systems Biology (CISBi, NAP/USP), Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14049-900, Brazil.
Tirapelli DP; Department of Genetics (CISBi/NAP), Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Monte Alegre, Ribeirão Preto-SP CEP: 14049-900, Brazil; Center for Integrative Systems Biology (CISBi, NAP/USP), Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14049-900, Brazil.
Rao A; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Mikkelsen T; Henry Ford Hospital, Detroit, MI 48202, USA.
Lau CC; Texas Children's Hospital, Houston, TX 77030, USA; Baylor College of Medicine, Houston, TX 77030, USA.
Yung WK; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rabadan R; Department of Neurology, Department of Pathology, Institute for Cancer Genetics, Department of Systems Biology and Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA.
Huse J; Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Brat DJ; Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
Lehman NL; Department of Pathology, The Ohio State University, Columbus, OH 43210, USA.
Barnholtz-Sloan JS; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA.
Zheng S; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Hess K; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rao G; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Meyerson M; The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Beroukhim R; The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.
Cooper L; Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
Akbani R; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Wrensch M; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA.
Haussler D; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Aldape KD; Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
Laird PW; Van Andel Research Institute, Grand Rapids, MI 49503, USA.
Gutmann DH; School of Medicine, Washington University, St. Louis, MO 63110, USA.
Noushmehr H; Department of Genetics (CISBi/NAP), Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Monte Alegre, Ribeirão Preto-SP CEP: 14049-900, Brazil; Center for Integrative Systems Biology (CISBi, NAP/USP), Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14049-900, Brazil. Electronic address: .
Iavarone A; Department of Neurology, Department of Pathology, Institute for Cancer Genetics, Department of Systems Biology and Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: .
Verhaak RG; Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Biostatistics, Department of Neuro-Oncology, Department of Neurosurgery, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: .
Pokaż więcej
Corporate Authors :
TCGA Research Network
Źródło :
Cell [Cell] 2016 Jan 28; Vol. 164 (3), pp. 550-63.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Transcriptome*
Brain Neoplasms/*genetics
Brain Neoplasms/*pathology
Glioma/*genetics
Glioma/*pathology
Adult ; Brain Neoplasms/metabolism ; Cell Proliferation ; Cluster Analysis ; DNA Helicases/genetics ; DNA Methylation ; Epigenesis, Genetic ; Glioma/metabolism ; Humans ; Isocitrate Dehydrogenase/genetics ; Middle Aged ; Mutation ; Nuclear Proteins/genetics ; Promoter Regions, Genetic ; Signal Transduction ; Telomerase/genetics ; Telomere ; X-linked Nuclear Protein
Czasopismo naukowe
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