Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Becker, J."" wg kryterium: Autor


Tytuł :
Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.
Autorzy :
Ugurel S; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: .
Schadendorf D; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Horny K; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Translational Skin Cancer Research, German Consortium of Translational Cancer Research (DKTK), Essen, Germany.
Sucker A; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Schramm S; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Utikal J; Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg and Department of Dermatology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany.
Pföhler C; Department of Dermatology, Saarland University Medical Center, Homburg/Saar, Germany.
Herbst R; Department of Dermatology, Helios Klinikum Erfurt, Erfurt, Germany.
Schilling B; Department of Dermatology, University Hospital Würzburg, Würzburg, Germany.
Blank C; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Becker JC; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Translational Skin Cancer Research, German Consortium of Translational Cancer Research (DKTK), Essen, Germany.
Paschen A; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Zimmer L; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Livingstone E; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Horn PA; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Rebmann V; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Pokaż więcej
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2020 Jan; Vol. 31 (1), pp. 144-152.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
B7-H1 Antigen*/blood
Melanoma*/drug therapy
Neoplasms, Second Primary*
Biomarkers, Tumor ; Humans ; Prognosis ; Programmed Cell Death 1 Receptor ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Adjuvant treatment with pegylated interferon α-2a versus low-dose interferon α-2a in patients with high-risk melanoma: a randomized phase III DeCOG trial.
Autorzy :
Eigentler TK; Department of Dermatology, Center for Dermatooncology, University Medical Center Tübingen, Tübingen .
Gutzmer R; Department of Dermatology and Allergy, Hannover Medical School, Hannover.
Hauschild A; Department of Dermatology, University Hospital Kiel, Kiel.
Heinzerling L; Department of Dermatology, University Hospital Erlangen, Erlangen.
Schadendorf D; Department of Dermatology, University Essen-Duisburg, Essen.
Nashan D; Department of Dermatology, Hospital Dortmund, Dortmund.
Hölzle E; Department of Dermatology, Hospital Oldenburg, Oldenburg.
Kiecker F; Department of Dermatology, Charité Berlin, Berlin.
Becker J; Department of Dermatology, University Essen-Duisburg, Essen.
Sunderkötter C; Department of Dermatology, University Hospital Münster, Münster.
Moll I; Department of Dermatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Richtig E; Department of Dermatology, University Hospital Graz, Graz, Austria.
Pönitzsch I; Department of Dermatology, University Hospital Leipzig, Leipzig, Germany.
Pehamberger H; Department of Dermatology, AKH Wien, University Hospital Vienna, Vienna, Austria.
Kaufmann R; Department of Dermatology, University Hospital Frankfurt am Main, Frankfurt/Main.
Pföhler C; Department of Dermatology, Saarland University Medical School, Homburg/Saar.
Vogt T; Department of Dermatology, Saarland University Medical School, Homburg/Saar.
Berking C; Department of Dermatology and Allergy, University Hospital of Munich, Munich, Germany.
Praxmarer M; Assign Group, Innsbruck, Austria.
Garbe C; Department of Dermatology, Center for Dermatooncology, University Medical Center Tübingen, Tübingen.
Pokaż więcej
Corporate Authors :
Dermatologic Cooperative Oncology Group (DeCOG)
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2016 Aug; Vol. 27 (8), pp. 1625-32. Date of Electronic Publication: 2016 Jun 10.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial
MeSH Terms :
Chemotherapy, Adjuvant/*methods
Drug-Related Side Effects and Adverse Reactions/*pathology
Interferon-alpha/*administration & dosage
Melanoma/*drug therapy
Polyethylene Glycols/*administration & dosage
Adolescent ; Adult ; Aged ; Chemotherapy, Adjuvant/adverse effects ; Disease-Free Survival ; Dose-Response Relationship, Drug ; Female ; Humans ; Interferon-alpha/adverse effects ; Male ; Melanoma/pathology ; Middle Aged ; Polyethylene Glycols/adverse effects ; Quality of Life ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A multicenter DeCOG study on predictors of vemurafenib therapy outcome in melanoma: pretreatment impacts survival.
Autorzy :
Ugurel S; Department of Dermatology, University of Essen, Essen Department of Dermatology, University of Würzburg, Würzburg .
Loquai C; Department of Dermatology, University of Mainz, Mainz.
Kähler K; Department of Dermatology, University of Kiel, Kiel.
Hassel J; Department of Dermatology, University of Heidelberg, Heidelberg.
Berking C; Department of Dermatology, Ludwig-Maximilians-University of München, München.
Zimmer L; Department of Dermatology, University of Essen, Essen.
Haubitz I; Institute of Biometry and Statistics, University of Würzburg, Würzburg.
Satzger I; Department of Dermatology, Hannover Medical School, Hannover, Germany.
Müller-Brenne T; Department of Dermatology, University of Mainz, Mainz.
Mikhaimer NC; Department of Dermatology, University of Kiel, Kiel.
Becker JC; Department of Dermatology, Medical University of Graz, Graz, Austria.
Kilian KJ; Department of Dermatology, Ludwig-Maximilians-University of München, München.
Schadendorf D; Department of Dermatology, University of Essen, Essen.
Heinzerling L; Department of Dermatology, University of Erlangen, Erlangen.
Kaatz M; Department of Dermatology, SRH Waldklinikum Gera, Gera Department of Dermatology, University of Jena, Jena.
Utikal J; Department of Dermatology, University Medical Center Mannheim, University of Heidelberg, Heidelberg.
Göppner D; Department of Dermatology, University of Magdeburg, Magdeburg.
Pföhler C; Department of Dermatology, Saarland University Hospital, Saarland.
Pflugfelder A; Department of Dermatology, University of Tübingen, Tübingen.
Mössner R; Department of Dermatology, University of Göttingen, Göttingen, Germany.
Gutzmer R; Department of Dermatology, Hannover Medical School, Hannover, Germany.
Pokaż więcej
Corporate Authors :
Dermatologic Cooperative Oncology Group (DeCOG)
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2015 Mar; Vol. 26 (3), pp. 573-82. Date of Electronic Publication: 2014 Dec 18.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Indoles/*administration & dosage
Melanoma/*diagnosis
Melanoma/*drug therapy
Skin Neoplasms/*diagnosis
Skin Neoplasms/*drug therapy
Sulfonamides/*administration & dosage
Adult ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome ; Vemurafenib
Czasopismo naukowe
Tytuł :
Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma.
Autorzy :
Heidenreich B; 1] Division of Molecular Genetic Epidemiology, German Cancer Research Center, 69120 Heidelberg, Germany [2].
Nagore E; 1] Department of Dermatology, Instituto Valenciano de Oncologia, Valencia 46009, Spain [2] Universidad Catolica de Valencia, Valencia 46001, Spain [3].
Rachakonda PS; Division of Molecular Genetic Epidemiology, German Cancer Research Center, 69120 Heidelberg, Germany.
Garcia-Casado Z; Laboratory of Molecular Biology, Instituto Valenciano de Oncologia, Valencia 46009, Spain.
Requena C; Department of Dermatology, Instituto Valenciano de Oncologia, Valencia 46009, Spain.
Traves V; Department of Pathology, Instituto Valenciano de Oncologia, Valencia 46009, Spain.
Becker J; Department of General Dermatology, Medical University of Graz, Graz 8036, Austria.
Soufir N; Departement de Genetique, Hôpital Bichat-Claude Bernard, APHP, Paris 75877, France.
Hemminki K; 1] Division of Molecular Genetic Epidemiology, German Cancer Research Center, 69120 Heidelberg, Germany [2] Center for Primary Health Care Research, Lund University, Malmö, Lund 221 00, Sweden.
Kumar R; Division of Molecular Genetic Epidemiology, German Cancer Research Center, 69120 Heidelberg, Germany.
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2014 Feb 26; Vol. 5, pp. 3401. Date of Electronic Publication: 2014 Feb 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Melanoma/*genetics
Promoter Regions, Genetic/*genetics
Skin Neoplasms/*genetics
Telomerase/*genetics
Adult ; Age Factors ; Aged ; Aged, 80 and over ; Base Sequence ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; DNA Mutational Analysis ; Female ; Gene Expression Regulation, Neoplastic ; Gene Frequency ; Genotype ; Humans ; Male ; Melanoma/pathology ; Middle Aged ; Multivariate Analysis ; Mutation ; Proto-Oncogene Proteins B-raf/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Factors ; Skin Neoplasms/pathology ; Sunlight
Czasopismo naukowe
Tytuł :
Upstream mitogen-activated protein kinase (MAPK) pathway inhibition: MEK inhibitor followed by a BRAF inhibitor in advanced melanoma patients.
Autorzy :
Goldinger SM; Department of Dermatology, University Hospital Zürich, Gloriastrasse 31, 8091 Zürich, Switzerland. Electronic address: .
Zimmer L; Department of Dermatology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Schulz C; Department of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany.
Ugurel S; Department of Dermatology, University Hospital Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.
Hoeller C; Department of Dermatology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
Kaehler KC; Department of Dermatology, University Hospital Schleswig-Holstein, Campus Kiel, Schittenhelmstrasse 7, 24105 Kiel, Germany.
Schadendorf D; Department of Dermatology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Hassel JC; Department of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany.
Becker J; Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria.
Hauschild A; Department of Dermatology, University Hospital Schleswig-Holstein, Campus Kiel, Schittenhelmstrasse 7, 24105 Kiel, Germany.
Dummer R; Department of Dermatology, University Hospital Zürich, Gloriastrasse 31, 8091 Zürich, Switzerland.
Pokaż więcej
Corporate Authors :
Dermatology Cooperative Oncology Group (DeCOG)
Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2014 Jan; Vol. 50 (2), pp. 406-10. Date of Electronic Publication: 2013 Oct 29.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
MAP Kinase Signaling System/*drug effects
Melanoma/*drug therapy
Mitogen-Activated Protein Kinases/*antagonists & inhibitors
Proto-Oncogene Proteins B-raf/*antagonists & inhibitors
Aged ; Aged, 80 and over ; Benzimidazoles/administration & dosage ; Disease Progression ; Disease-Free Survival ; Feasibility Studies ; Female ; Humans ; Imidazoles/administration & dosage ; Indoles/administration & dosage ; Male ; Melanoma/genetics ; Middle Aged ; Mitogen-Activated Protein Kinases/metabolism ; Mutation ; Outcome Assessment, Health Care/methods ; Oximes/administration & dosage ; Protein Kinase Inhibitors/administration & dosage ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins B-raf/metabolism ; Pyridones/administration & dosage ; Pyrimidinones/administration & dosage ; Retrospective Studies ; Sulfonamides/administration & dosage ; Time Factors ; Vemurafenib
Czasopismo naukowe
Tytuł :
BRAF mutation analysis of only one metastatic lesion can restrict the treatment of melanoma: a case report.
Autorzy :
Richtig E
Schrama D
Ugurel S
Fried I
Niederkorn A
Massone C
Becker JC
Pokaż więcej
Źródło :
The British journal of dermatology [Br J Dermatol] 2013 Feb; Vol. 168 (2), pp. 428-30. Date of Electronic Publication: 2012 Sep 27.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Melanoma/*genetics
Mutation/*genetics
Proto-Oncogene Proteins B-raf/*genetics
Skin Neoplasms/*genetics
Aged ; Breast Neoplasms/genetics ; Breast Neoplasms/secondary ; DNA Mutational Analysis/adverse effects ; Fatal Outcome ; Female ; Humans ; Lymphatic Metastasis ; Melanoma/drug therapy ; Melanoma/secondary ; Neoplasms, Second Primary/genetics ; Neoplasms, Second Primary/pathology ; Skin Neoplasms/drug therapy ; Skin Neoplasms/secondary ; Time-to-Treatment
Raport
Tytuł :
Sorafenib and pegylated interferon-α2b in advanced metastatic melanoma: a multicenter phase II DeCOG trial.
Autorzy :
Egberts F; Department of Dermatology, University of Kiel, Kiel.
Gutzmer R; Department of Dermatology, Hannover Medical School, Hannover.
Ugurel S; Department of Dermatology, University of Würzburg, Würzburg, Germany; Department of Dermatology, University of Graz, Graz, Austria.
Becker JC; Department of Dermatology, University of Würzburg, Würzburg, Germany; Department of Dermatology, University of Graz, Graz, Austria.
Trefzer U; Department of Dermatology, University of Berlin, Berlin.
Degen A; Department of Dermatology, Hannover Medical School, Hannover.
Schenck F; Department of Dermatology, Hannover Medical School, Hannover.
Frey L; Department of Dermatology, University of Würzburg, Würzburg, Germany.
Wilhelm T; Department of Dermatology, University of Berlin, Berlin.
Hassel JC; Department of Dermatology, University of Heidelberg-Mannheim, Heidelberg.
Schadendorf D; Department of Dermatology, University of Essen, Essen.
Livingstone E; Department of Dermatology, University of Kiel, Kiel; Department of Dermatology, University of Essen, Essen.
Mauch C; Department of Dermatology, University of Köln, Köln.
Garbe C; Department of Dermatology, University of Tübingen, Tübingen.
Berking C; Department of Dermatology, University of Munich, Munich.
Rass K; Department of Dermatology, University of Homburg/Saar, Homburg/Saar.
Mohr P; Dermatological Center, Buxtehude, Buxtehude, Germany.
Kaehler KC; Department of Dermatology, University of Kiel, Kiel.
Weichenthal M; Department of Dermatology, University of Kiel, Kiel.
Hauschild A; Department of Dermatology, University of Kiel, Kiel. Electronic address: .
Pokaż więcej
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2011 Jul; Vol. 22 (7), pp. 1667-1674. Date of Electronic Publication: 2011 Jan 10.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Antiviral Agents/*therapeutic use
Benzenesulfonates/*therapeutic use
Head and Neck Neoplasms/*drug therapy
Interferon-alpha/*therapeutic use
Melanoma/*drug therapy
Polyethylene Glycols/*therapeutic use
Pyridines/*therapeutic use
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols ; Female ; Follow-Up Studies ; Head and Neck Neoplasms/pathology ; Humans ; Interferon alpha-2 ; Male ; Maximum Tolerated Dose ; Melanoma/secondary ; Middle Aged ; Neoplasm Staging ; Niacinamide/analogs & derivatives ; Phenylurea Compounds ; Prospective Studies ; Recombinant Proteins ; Sorafenib ; Survival Rate ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032).
Autorzy :
Patel PM; Academic Unit of Clinical Oncology, University of Nottingham, Nottingham, United Kingdom. />Suciu S
Mortier L
Kruit WH
Robert C
Schadendorf D
Trefzer U
Punt CJ
Dummer R
Davidson N
Becker J
Conry R
Thompson JA
Hwu WJ
Engelen K
Agarwala SS
Keilholz U
Eggermont AM
Spatz A
Pokaż więcej
Corporate Authors :
EORTC Melanoma Group
Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2011 Jul; Vol. 47 (10), pp. 1476-83. Date of Electronic Publication: 2011 May 18.
Typ publikacji :
Clinical Trial, Phase III; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Dacarbazine/*analogs & derivatives
Dacarbazine/*therapeutic use
Melanoma/*drug therapy
Skin Neoplasms/*drug therapy
Aged ; Area Under Curve ; Dacarbazine/administration & dosage ; Drug Administration Schedule ; Female ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Neoplasm Staging ; Remission Induction ; Safety ; Temozolomide ; Time Factors
Czasopismo naukowe
Tytuł :
[Treatment of advanced metastatic melanoma].
Autorzy :
Ugurel S; Allgemeine Dermatologie, Medizinische Universität Graz, Österreich.
Becker JC
Pokaż więcej
Transliterated Title :
Therapie des inoperabel metastasierten Melanoms.
Źródło :
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete [Hautarzt] 2011 Jun; Vol. 62 (6), pp. 423-9.
Typ publikacji :
English Abstract; Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Immunotherapy/*trends
Melanoma/*drug therapy
Melanoma/*secondary
Molecular Targeted Therapy/*trends
Radiotherapy, Conformal/*trends
Skin Neoplasms/*therapy
Humans ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Multicentre study on standardisation of melanoma cell culture--an initiative of the German Melanoma Research Network.
Autorzy :
Eberle J
Spangler B
Becker JC
Heinemann SH
Klein CA
Kunz M
Kuphal S
Langer P
Mauch C
Meierjohann S
Paschen A
Schadendorf D
Schartl M
Schittek B
Schönherr R
Tüting T
Zigrino P
Bosserhoff AK
Pokaż więcej
Corporate Authors :
German Melanoma Research Network of the German Cancer Aid
Źródło :
Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2010 Apr; Vol. 23 (2), pp. 296-8. Date of Electronic Publication: 2010 Feb 05.
Typ publikacji :
Letter
MeSH Terms :
Multicenter Studies as Topic*
Cell Culture Techniques/*standards
Melanoma/*pathology
Skin Neoplasms/*pathology
Artifacts ; Germany ; Humans ; Tumor Cells, Cultured
Opinia redakcyjna
Tytuł :
Stem cells, melanoma and cancer stem cells: the good, the bad and the evil?
Autorzy :
Menaa F; Department of Dermatology and Dermato-Oncology, University of Wuerzburg, School of Medicine, Wuerzburg, Germany.
Houben R
Eyrich M
Broecker EB
Becker JC
Wischhusen J
Pokaż więcej
Źródło :
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia [G Ital Dermatol Venereol] 2009 Jun; Vol. 144 (3), pp. 287-96. Date of Electronic Publication: 2008 Dec 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Melanoma/*pathology
Neoplastic Stem Cells/*pathology
Stem Cells/*cytology
Animals ; Antineoplastic Agents/pharmacology ; Biomarkers, Tumor ; Cell Cycle ; Cell Dedifferentiation ; Clone Cells/pathology ; Drug Delivery Systems ; Drug Resistance, Neoplasm ; Humans ; Neoplasm Proteins/physiology ; Neoplasms/etiology ; Neoplasms/pathology ; Neoplasms/therapy ; Neoplastic Stem Cells/drug effects ; Signal Transduction
Czasopismo naukowe
Tytuł :
[Spectroscopic imaging of the human liver using 3D CSI: optimization and application in patients with metastatic uvea melanoma].
Autorzy :
Beer M; Institut für Röntgendiagnostik, Universitätsklinikum Würzburg. />Winkelmann V
Becker JC
Terheyden P
Stenzel M
Bröcker EB
Hahn D
Köstler H
Pokaż więcej
Transliterated Title :
Spektroskopische bildgebung der menschlichen leber mittels 3D-CSI: etablierung und anwendung bei patienten mit metastasiertem aderhautmelanom.
Źródło :
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin [Rofo] 2009 Jan; Vol. 181 (1), pp. 60-6. Date of Electronic Publication: 2008 Dec 11.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Choroid Neoplasms/*physiopathology
Energy Metabolism/*physiology
Image Processing, Computer-Assisted/*methods
Imaging, Three-Dimensional/*methods
Liver Neoplasms/*secondary
Magnetic Resonance Imaging/*methods
Magnetic Resonance Spectroscopy/*methods
Melanoma/*secondary
Adenosine Triphosphate/metabolism ; Adult ; Aged ; Choroid Neoplasms/diagnosis ; Female ; Humans ; Liver/physiopathology ; Liver Neoplasms/diagnosis ; Liver Neoplasms/physiopathology ; Male ; Melanoma/diagnosis ; Melanoma/physiopathology ; Middle Aged ; Observer Variation ; Phosphocreatine/metabolism ; Phospholipids/metabolism ; Reference Values ; Sensitivity and Specificity ; Young Adult
Czasopismo naukowe
Tytuł :
[Immunmodulatory antibodies in the treatment of skin cancer].
Autorzy :
Schrama D; Klinik für Dermatologie, Allergologie und Venerologie, Universitätshautklinik Würzburg, Josef-Schneider-Strasse 2, 97080, Würzburg, Deutschland.
Hauschild A
Becker JC
Pokaż więcej
Transliterated Title :
Immunmodulierende Antikörper in der Dermatoonkologie.
Źródło :
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete [Hautarzt] 2008 Oct; Vol. 59 (10), pp. 806-13.
Typ publikacji :
English Abstract; Journal Article; Review
MeSH Terms :
Antibodies/*therapeutic use
Immunotherapy/*methods
Melanoma/*drug therapy
Melanoma/*immunology
Skin Neoplasms/*drug therapy
Skin Neoplasms/*immunology
Humans
Czasopismo naukowe
Tytuł :
Temozolomide plus pegylated interferon alfa-2b as first-line treatment for stage IV melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group (DeCOG).
Autorzy :
Spieth K; Department of Dermatology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany. />Kaufmann R
Dummer R
Garbe C
Becker JC
Hauschild A
Tilgen W
Ugurel S
Beyeler M
Bröcker EB
Kaehler KC
Pföhler C
Gille J
Leiter U
Schadendorf D
Pokaż więcej
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2008 Apr; Vol. 19 (4), pp. 801-6. Date of Electronic Publication: 2008 Jan 04.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Melanoma/*drug therapy
Melanoma/*secondary
Skin Neoplasms/*drug therapy
Skin Neoplasms/*pathology
Adult ; Aged ; Antineoplastic Agents, Alkylating/administration & dosage ; Antineoplastic Agents, Alkylating/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Dacarbazine/administration & dosage ; Dacarbazine/adverse effects ; Dacarbazine/analogs & derivatives ; Disease-Free Survival ; Drug Administration Schedule ; Female ; Humans ; Interferon alpha-2 ; Interferon-alpha/administration & dosage ; Interferon-alpha/adverse effects ; Male ; Middle Aged ; Neoplasm Staging ; Polyethylene Glycols ; Prospective Studies ; Recombinant Proteins ; Temozolomide ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Prognostic factors and therapy for primary anorectal melanoma.
Autorzy :
Weyandt GH
Becker JC
Pokaż więcej
Źródło :
International journal of colorectal disease [Int J Colorectal Dis] 2006 Jul; Vol. 21 (5), pp. 488-9. Date of Electronic Publication: 2005 Mar 16.
Typ publikacji :
Comment; Letter
MeSH Terms :
Anus Neoplasms/*surgery
Melanoma/*surgery
Rectal Neoplasms/*surgery
Anus Neoplasms/diagnosis ; Anus Neoplasms/pathology ; Humans ; Melanoma/diagnosis ; Melanoma/pathology ; Prognosis ; Rectal Neoplasms/diagnosis ; Rectal Neoplasms/pathology
Opinia redakcyjna
Tytuł :
Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG.
Autorzy :
Schadendorf D; Skin Cancer Unit, German Cancer Research Center & University Hospital Mannheim, Mannheim. />Ugurel S
Schuler-Thurner B
Nestle FO
Enk A
Bröcker EB
Grabbe S
Rittgen W
Edler L
Sucker A
Zimpfer-Rechner C
Berger T
Kamarashev J
Burg G
Jonuleit H
Tüttenberg A
Becker JC
Keikavoussi P
Kämpgen E
Schuler G
Pokaż więcej
Corporate Authors :
DC study group of the DeCOG
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2006 Apr; Vol. 17 (4), pp. 563-70. Date of Electronic Publication: 2006 Jan 17.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Cancer Vaccines/*administration & dosage
Dacarbazine/*therapeutic use
Dendritic Cells/*transplantation
Melanoma/*therapy
Peptides/*administration & dosage
Humans ; Melanoma/pathology ; Neoplasm Metastasis
Czasopismo naukowe
Tytuł :
CD28-mediated costimulation impacts on the differentiation of DC vaccination-induced T cell responses.
Autorzy :
Voigt H; Department of Dermatology, Julius-Maximilians-Univerity, Würzburg, Germany.
Schrama D
Eggert AO
Vetter CS
Müller-Blech K
Reichardt HM
Andersen MH
Becker JC
Lühder F
Pokaż więcej
Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2006 Jan; Vol. 143 (1), pp. 93-102.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adoptive Transfer*
CD28 Antigens/*immunology
Dendritic Cells/*immunology
Melanoma/*prevention & control
Skin Neoplasms/*prevention & control
T-Lymphocytes/*immunology
Animals ; CD28 Antigens/analysis ; CD28 Antigens/genetics ; Clone Cells ; Cytotoxicity Tests, Immunologic ; Immunohistochemistry/methods ; Interferon-gamma/analysis ; Lymphocyte Activation ; Melanoma/immunology ; Melanoma/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neoplasm Transplantation ; Receptors, Antigen, T-Cell/analysis ; Skin Neoplasms/immunology ; Skin Neoplasms/pathology ; Vaccination
Czasopismo naukowe
Tytuł :
STAT5 contributes to interferon resistance of melanoma cells.
Autorzy :
Wellbrock C; Department of Physiological Chemistry I, Biocenter, Theodor-Boveri Institute, University of Würzburg, Am Hubland, 97074 Würzburg, Germany. />Weisser C
Hassel JC
Fischer P
Becker J
Vetter CS
Behrmann I
Kortylewski M
Heinrich PC
Schartl M
Pokaż więcej
Źródło :
Current biology : CB [Curr Biol] 2005 Sep 20; Vol. 15 (18), pp. 1629-39.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Drug Resistance, Neoplasm/*physiology
Immunotherapy/*adverse effects
Interferon-alpha/*pharmacology
Melanoma/*metabolism
STAT1 Transcription Factor/*metabolism
STAT5 Transcription Factor/*metabolism
Blotting, Western ; Cell Line, Tumor ; Cytokines/antagonists & inhibitors ; DNA Primers ; Drug Resistance, Neoplasm/drug effects ; Fluorescent Antibody Technique ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Immunohistochemistry ; Immunoprecipitation ; Interferon-alpha/metabolism ; Melanoma/therapy ; RNA Interference ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Lack of clinical efficacy of imatinib in metastatic melanoma.
Autorzy :
Ugurel S; German Cancer Research Center Heidelberg, Department of Dermatology, University Hospital of Mannheim, Theodor-Kutzer-Ufer 1, D-68167 Mannheim, Germany. />Hildenbrand R
Zimpfer A
La Rosée P
Paschka P
Sucker A
Keikavoussi P
Becker JC
Rittgen W
Hochhaus A
Schadendorf D
Pokaż więcej
Źródło :
British journal of cancer [Br J Cancer] 2005 Apr 25; Vol. 92 (8), pp. 1398-405.
Typ publikacji :
Clinical Trial; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Melanoma/*drug therapy
Piperazines/*therapeutic use
Pyrimidines/*therapeutic use
Adult ; Aged ; Base Sequence ; Benzamides ; Cell Line, Tumor ; Cell Proliferation/drug effects ; DNA Mutational Analysis ; Female ; Humans ; Imatinib Mesylate ; Immunohistochemistry ; Male ; Melanoma/mortality ; Middle Aged ; Molecular Sequence Data ; Neoplasm Metastasis/drug therapy ; Proto-Oncogene Proteins c-kit/drug effects ; Proto-Oncogene Proteins c-kit/genetics ; Proto-Oncogene Proteins c-kit/metabolism ; Receptors, Platelet-Derived Growth Factor/drug effects ; Receptors, Platelet-Derived Growth Factor/genetics ; Receptors, Platelet-Derived Growth Factor/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Loss of nonclassical MHC molecules MIC-A/B expression during progression of uveal melanoma.
Autorzy :
Vetter CS; Department of Dermatology, University of Wuerzburg, Josef-Schneider-Str. 2, 97080 Wuerzburg, Germany.
Lieb W
Bröcker EB
Becker JC
Pokaż więcej
Źródło :
British journal of cancer [Br J Cancer] 2004 Oct 18; Vol. 91 (8), pp. 1495-9.
Typ publikacji :
Journal Article
MeSH Terms :
Histocompatibility Antigens Class I/*metabolism
Melanoma/*metabolism
Uveal Neoplasms/*metabolism
CD57 Antigens/metabolism ; Disease Progression ; Humans ; Immunity, Cellular ; Immunoenzyme Techniques ; Ligands ; Melanoma/pathology ; Membrane Proteins/metabolism ; NK Cell Lectin-Like Receptor Subfamily K ; Receptors, Immunologic/metabolism ; Receptors, Natural Killer Cell ; Skin Neoplasms/metabolism ; Skin Neoplasms/pathology ; Uveal Neoplasms/pathology
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies