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    Wyświetlanie 1-12 z 12
    Tytuł:
    PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.
    Autorzy:
    Fanelli G; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
    Romano M; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
    Nova-Lamperti E; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
    Werner Sunderland M; Cancer Immunology Unit, University College London (UCL) Cancer Institute, London, United Kingdom.
    Nerviani A; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London and Barts' Health NHS Trust, London, United Kingdom.
    Scottà C; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
    Bombardieri M; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London and Barts' Health NHS Trust, London, United Kingdom.
    Quezada SA; Cancer Immunology Unit, University College London (UCL) Cancer Institute, London, United Kingdom.
    Sacks SH; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
    Noelle RJ; Department of Microbiology and Immunology, Norris Cotton Cancer Center Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America.
    Pitzalis C; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London and Barts' Health NHS Trust, London, United Kingdom.
    Lechler RI; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.; King's Health Partners, London, United Kingdom.
    Lombardi G; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
    Becker PD; MRC Centre for Transplantation, School of Immunology and Microbial Sciences, King's College London, Guy's Hospital, London, United Kingdom.
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    Źródło:
    PLoS biology [PLoS Biol] 2021 Apr 26; Vol. 19 (4), pp. e3001199. Date of Electronic Publication: 2021 Apr 26 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    B7-H1 Antigen/*metabolism
    CD4-Positive T-Lymphocytes/*physiology
    T-Lymphocytes, Regulatory/*physiology
    B7-H1 Antigen/physiology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/physiology ; Cell Transdifferentiation/genetics ; Cell Transdifferentiation/immunology ; Cohort Studies ; Humans ; Immune Tolerance/genetics ; Immune Tolerance/immunology ; Immunologic Memory/physiology ; Leukocyte Common Antigens/metabolism ; Phenotype ; Programmed Cell Death 1 Receptor/metabolism ; Programmed Cell Death 1 Receptor/physiology ; Signal Transduction/physiology ; T-Lymphocytes, Regulatory/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Author Correction: Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model.
    Autorzy:
    Alhabbab R; Centre of Immunology, Division of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Blair P; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Elgueta R; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Stolarczyk E; Division of Diabetes and Nutritional Sciences, King's College London, Guy's Hospital, London, SE1 9RT, UK.
    Marks E; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Becker PD; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Ratnasothy K; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Smyth L; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Safinia N; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Sharif-Paghaleh E; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    O'Connell S; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Noelle RJ; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Lord GM; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Howard JK; Division of Diabetes and Nutritional Sciences, King's College London, Guy's Hospital, London, SE1 9RT, UK.
    Spencer J; Peter Gorer Department of Immunobiology, King's College London, Guy's Hospital, London, SE1 9RT, UK.
    Lechler RI; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK.
    Lombardi G; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, SE1 9RT, UK. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Apr 06; Vol. 10 (1), pp. 6166. Date of Electronic Publication: 2020 Apr 06.
    Typ publikacji:
    Published Erratum
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses.
    Autorzy:
    Nova-Lamperti E; King's College London, MRC Centre for Transplantation, London, United Kingdom.
    Fanelli G; King's College London, MRC Centre for Transplantation, London, United Kingdom.
    Becker PD; King's College London, MRC Centre for Transplantation, London, United Kingdom.
    Chana P; BRC Flow Cytometry Laboratory, Guy's Hospital, London, United Kingdom.
    Elgueta R; King's College London, MRC Centre for Transplantation, London, United Kingdom.
    Dodd PC; King's College London, MRC Centre for Transplantation, London, United Kingdom.
    Lord GM; King's College London, MRC Centre for Transplantation, London, United Kingdom.; NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London, Guy's Hospital, London, United Kingdom.
    Lombardi G; King's College London, MRC Centre for Transplantation, London, United Kingdom.
    Hernandez-Fuentes MP; King's College London, MRC Centre for Transplantation, London, United Kingdom.; NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London, Guy's Hospital, London, United Kingdom.
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    Źródło:
    Scientific reports [Sci Rep] 2016 Jan 22; Vol. 6, pp. 20044. Date of Electronic Publication: 2016 Jan 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Down-Regulation*
    B7-2 Antigen/*metabolism
    CD4-Positive T-Lymphocytes/*metabolism
    Interleukin-10/*biosynthesis
    Precursor Cells, B-Lymphoid/*metabolism
    Adult ; Aged ; Autocrine Communication ; CD4-Positive T-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/immunology ; Cell Proliferation ; Female ; Healthy Volunteers ; Humans ; Immune Tolerance ; Kidney Transplantation ; Male ; Middle Aged ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model.
    Autorzy:
    Alhabbab R; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Blair P; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Elgueta R; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Stolarczyk E; Division of Diabetes and Nutritional Sciences, King's College London, Guy's Hospital, London SE1 9RT, UK.
    Marks E; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Becker PD; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Ratnasothy K; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Smyth L; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Safinia N; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Sharif-Paghaleh E; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    O'Connell S; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Noelle RJ; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Lord GM; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Howard JK; Division of Diabetes and Nutritional Sciences, King's College London, Guy's Hospital, London SE1 9RT, UK.
    Spencer J; Peter Gorer Department of Immunobiology, King's College London, Guy's Hospital, London SE1 9RT, UK.
    Lechler RI; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
    Lombardi G; Medical Research Council Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.
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    Źródło:
    Scientific reports [Sci Rep] 2015 Jun 25; Vol. 5, pp. 11554. Date of Electronic Publication: 2015 Jun 25.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gastrointestinal Microbiome*/drug effects
    Skin Transplantation*
    B-Lymphocytes/*immunology
    Adaptive Immunity ; Adoptive Transfer ; Animals ; Anti-Bacterial Agents/pharmacology ; B-Lymphocytes/cytology ; B-Lymphocytes/enzymology ; Cytokines/metabolism ; Disease Models, Animal ; Graft Survival/immunology ; Histocompatibility Antigens Class I/genetics ; Histocompatibility Antigens Class I/metabolism ; Immune Tolerance ; Interleukin-10/deficiency ; Interleukin-10/genetics ; Lipopolysaccharides/toxicity ; Lymph Nodes/immunology ; Lymph Nodes/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Spleen/immunology ; Spleen/pathology ; Transplantation, Homologous
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Cyclic di-nucleotides: new era for small molecules as adjuvants.
    Autorzy:
    Libanova R; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany. />Becker PD
    Guzmán CA
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    Źródło:
    Microbial biotechnology [Microb Biotechnol] 2012 Mar; Vol. 5 (2), pp. 168-76. Date of Electronic Publication: 2011 Sep 29.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Adjuvants, Immunologic/*pharmacology
    Nucleotides, Cyclic/*pharmacology
    Vaccination/*methods
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice.
    Autorzy:
    Becker PD; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.
    Legrand N
    van Geelen CM
    Noerder M
    Huntington ND
    Lim A
    Yasuda E
    Diehl SA
    Scheeren FA
    Ott M
    Weijer K
    Wedemeyer H
    Di Santo JP
    Beaumont T
    Guzman CA
    Spits H
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    Źródło:
    PloS one [PLoS One] 2010 Oct 04; Vol. 5 (10). Date of Electronic Publication: 2010 Oct 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Immune System*
    Antibodies, Monoclonal/*biosynthesis
    B-Lymphocytes/*immunology
    Immunoglobulin M/*immunology
    Animals ; Cell Line, Transformed ; Cell Separation ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Mice ; Mice, Inbred BALB C
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Modified vaccinia virus Ankara exerts potent immune modulatory activities in a murine model.
    Autorzy:
    Nörder M; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
    Becker PD
    Drexler I
    Link C
    Erfle V
    Guzmán CA
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    Źródło:
    PloS one [PLoS One] 2010 Jun 30; Vol. 5 (6), pp. e11400. Date of Electronic Publication: 2010 Jun 30.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Models, Animal*
    Vaccinia virus/*immunology
    Viral Vaccines/*immunology
    Adjuvants, Immunologic ; Animals ; Antibody Formation/immunology ; Antigen Presentation/immunology ; Antigens, Viral/administration & dosage ; Antigens, Viral/chemistry ; Antigens, Viral/immunology ; CD8-Positive T-Lymphocytes/immunology ; Dendritic Cells/immunology ; Female ; Immunization ; Immunoglobulin G/immunology ; Mice ; Mice, Inbred C57BL ; Ovalbumin/administration & dosage ; Ovalbumin/chemistry ; Ovalbumin/immunology ; Safety ; Solubility ; Vaccines, Attenuated/administration & dosage ; Vaccines, Attenuated/adverse effects ; Vaccines, Attenuated/immunology ; Viral Vaccines/administration & dosage ; Viral Vaccines/adverse effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Evolution of hepatitis C virus hypervariable region 1 in immunocompetent children born to HCV-infected mothers.
    Autorzy:
    Gismondi MI; Laboratorio de Biología Molecular, División Patología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina.
    Becker PD
    Díaz Carrasco JM
    Guzmán CA
    Campos RH
    Preciado MV
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    Źródło:
    Journal of viral hepatitis [J Viral Hepat] 2009 May; Vol. 16 (5), pp. 332-9. Date of Electronic Publication: 2009 Feb 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Evolution, Molecular*
    Mutation, Missense*
    Point Mutation*
    Hepacivirus/*genetics
    Hepatitis C, Chronic/*virology
    Amino Acid Sequence ; Child, Preschool ; Conserved Sequence ; Follow-Up Studies ; Hepacivirus/immunology ; Hepatitis C, Chronic/immunology ; Humans ; Molecular Sequence Data ; Plasma/virology ; Selection, Genetic ; Sequence Analysis, DNA
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit.
    Autorzy:
    Royo JL; Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-Consejo Superior de Investigaciones Científicas, Carretera, Utrera, Km 1, E-41013 Sevilla, Spain.
    Becker PD
    Camacho EM
    Cebolla A
    Link C
    Santero E
    Guzmán CA
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    Źródło:
    Nature methods [Nat Methods] 2007 Nov; Vol. 4 (11), pp. 937-42. Date of Electronic Publication: 2007 Oct 07.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Aspirin/*pharmacology
    Gene Expression/*drug effects
    Gene Expression Regulation, Bacterial/*drug effects
    Salmonella enterica/*drug effects
    3-Phosphoshikimate 1-Carboxyvinyltransferase/genetics ; 3-Phosphoshikimate 1-Carboxyvinyltransferase/metabolism ; Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cell Line, Tumor ; Flucytosine/metabolism ; Fluorouracil/metabolism ; Fluorouracil/therapeutic use ; Genetic Engineering/methods ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HeLa Cells ; Humans ; Lac Operon/genetics ; Macrophages/drug effects ; Macrophages/metabolism ; Macrophages/microbiology ; Mice ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Neoplasms/microbiology ; Operon/genetics ; Promoter Regions, Genetic/genetics ; Salmonella Infections/drug therapy ; Salmonella Infections/microbiology ; Salmonella enterica/genetics ; Salmonella enterica/metabolism ; Sodium Salicylate/pharmacology ; Spleen/drug effects ; Spleen/metabolism ; Spleen/microbiology ; Transcription Factors/genetics ; Transcription Factors/metabolism ; beta-Galactosidase/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-12 z 12

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