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Wyszukujesz frazę ""Beer, David G."" wg kryterium: Autor


Tytuł:
18F-FDG PET intensity correlates with a hypoxic gene signature and other oncogenic abnormalities in operable non-small cell lung cancer.
Autorzy:
Heiden BT; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Chen G; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Hermann M; Department of Radiology, Division of Nuclear Medicine, University of Michigan, Ann Arbor, MI, United States of America.
Brown RKJ; Department of Radiology, Division of Nuclear Medicine, University of Michigan, Ann Arbor, MI, United States of America.
Orringer MB; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Lin J; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Chang AC; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Carrott PW; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Lynch WR; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Zhao L; Biostatistics Unit, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, United States of America.
Beer DG; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Reddy RM; Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Jul 02; Vol. 13 (7), pp. e0199970. Date of Electronic Publication: 2018 Jul 02 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Positron-Emission Tomography*
Carcinoma, Non-Small-Cell Lung/*diagnostic imaging
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*diagnostic imaging
Lung Neoplasms/*genetics
Oncogenes/*genetics
Tumor Hypoxia/*genetics
Aged ; Biological Transport ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/surgery ; Female ; Fluorodeoxyglucose F18/metabolism ; Genomics ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Prognosis
Czasopismo naukowe
Tytuł:
Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study.
Autorzy:
Sun X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, United States of America.
Chandar AK; Division of Gastroenterology and Hepatology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Canto MI; Division of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, MD, United States of America.
Thota PN; Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, United States of America.
Brock M; Department of Cardiology and Thoracic Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, United States of America.
Shaheen NJ; Center for Esophageal Diseases & Swallowing, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.
Beer DG; Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, United States of America.
Wang JS; Division of Gastroenterology, Washington University School of Medicine, St Louis, MO, United States of America.
Falk GW; University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United states of America.
Iyer PG; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States of America.
Abrams JA; Department of Medicine, Columbia University Medical Center, New York, NY, United States of America.
Venkat-Ramani M; Division of Gastroenterology and Hepatology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Veigl M; Division of General Medical Sciences (Oncology), Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Miron A; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Willis J; Department of Pathology, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Patil DT; Department of Pathology, Cleveland Clinic, Cleveland, OH, United States of America.
Nalbantoglu I; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States of America.
Guda K; Division of General Medical Sciences (Oncology), Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Markowitz SD; Division of Oncology and Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, United States of America.
Elston R; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, United States of America.
Chak A; Division of Gastroenterology and Hepatology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.; Division of General Medical Sciences (Oncology), Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Oct 26; Vol. 12 (10), pp. e0184962. Date of Electronic Publication: 2017 Oct 26 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Black or African American*
Genetic Predisposition to Disease*
Adenocarcinoma/*genetics
Barrett Esophagus/*genetics
Esophageal Neoplasms/*genetics
Adenocarcinoma/ethnology ; Barrett Esophagus/ethnology ; Esophageal Neoplasms/ethnology ; Humans
Czasopismo naukowe
Tytuł:
Overexpression of FAM83H-AS1 indicates poor patient survival and knockdown impairs cell proliferation and invasion via MET/EGFR signaling in lung cancer.
Autorzy:
Zhang J; Xian Jiaotong University, Xi'an, China.; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Feng S; Xinjiang Medical University, Urumqi, China.
Su W; Guangdong Medical University, Zhanjiang, China.
Bai S; Xinjiang Medical University, Urumqi, China.
Xiao L; Xinjiang Medical University, Urumqi, China.
Wang L; Guangxi Medical University, Nanning, China.
Thomas DG; Department of Pathology, University of Michigan, USA.
Lin J; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Reddy RM; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Carrott PW; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Lynch WR; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Chang AC; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Beer DG; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Guo YM; Xian Jiaotong University, Xi'an, China.
Chen G; Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
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Źródło:
Scientific reports [Sci Rep] 2017 Feb 15; Vol. 7, pp. 42819. Date of Electronic Publication: 2017 Feb 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*
Up-Regulation*
Gene Expression Profiling/*methods
Lung Neoplasms/*genetics
RNA, Long Noncoding/*genetics
Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; High-Throughput Nucleotide Sequencing ; Humans ; Lung Neoplasms/metabolism ; Neoplasm Invasiveness ; Prognosis ; Proto-Oncogene Proteins c-met/genetics ; Proto-Oncogene Proteins c-met/metabolism ; Sequence Analysis, RNA ; Survival Analysis
Czasopismo naukowe
Tytuł:
Using second harmonic generation to predict patient outcome in solid tumors.
Autorzy:
Burke K; Department of Biomedical Engineering, University of Rochester, 207 Robert B. Goergen Hall, Box 270168, Rochester, NY, 14627, USA. Kathleen_.
Smid M; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands. .
Dawes RP; Neuroscience Graduate Program, University of Rochester, 601 Elmwood Ave, Rochester, NY, 14642, USA. Ryan_.
Timmermans MA; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands. .
Salzman P; Department of Biostatistics and Computational Biology, University of Rochester, 601 Elmwood Ave, Rochester, NY, 14642, USA. .
van Deurzen CH; Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands. .
Beer DG; Departments of Surgery and Radiation Oncology, University of Michigan, Ann Arbor, MI, 48109, USA. .
Foekens JA; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands. .
Brown E; Department of Biomedical Engineering, University of Rochester, 207 Robert B. Goergen Hall, Box 270168, Rochester, NY, 14627, USA. Edward_.; Department of Neurobiology and Anatomy, University of Rochester, 601 Elmwood Ave, Rochester, NY, 14642, USA. Edward_.
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Źródło:
BMC cancer [BMC Cancer] 2015 Nov 24; Vol. 15, pp. 929. Date of Electronic Publication: 2015 Nov 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Breast Neoplasms/*pathology
Molecular Imaging/*methods
Optical Imaging/*methods
Adenocarcinoma/pathology ; Adult ; Aged ; Antineoplastic Agents, Hormonal/therapeutic use ; Breast Neoplasms/chemistry ; Breast Neoplasms/drug therapy ; Collagen/chemistry ; Colorectal Neoplasms/pathology ; Female ; Humans ; Lung Neoplasms/pathology ; Middle Aged ; Predictive Value of Tests ; Receptors, Estrogen ; Retrospective Studies ; Survival Analysis ; Tamoxifen/therapeutic use
Czasopismo naukowe
Tytuł:
Paired exome analysis of Barrett's esophagus and adenocarcinoma.
Autorzy:
Stachler MD; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Taylor-Weiner A; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
Peng S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
McKenna A; University of Washington, Seattle, Washington, USA.
Agoston AT; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Odze RD; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Davison JM; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Nason KS; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Loda M; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Leshchiner I; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
Stewart C; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
Stojanov P; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
Seepo S; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
Lawrence MS; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
Ferrer-Torres D; Section of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Lin J; Section of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Chang AC; Section of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Gabriel SB; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
Lander ES; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Beer DG; Section of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Getz G; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Carter SL; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, Massachusetts, USA.; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.
Bass AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Eli and Edythe L. Broad Institute, Cambridge, Massachusetts, USA.
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Źródło:
Nature genetics [Nat Genet] 2015 Sep; Vol. 47 (9), pp. 1047-55. Date of Electronic Publication: 2015 Jul 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Exome*
Adenocarcinoma/*genetics
Barrett Esophagus/*genetics
Esophageal Neoplasms/*genetics
Class I Phosphatidylinositol 3-Kinases ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; DNA Mutational Analysis ; Gene Amplification ; Gene Frequency ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Phosphatidylinositol 3-Kinases/genetics ; Point Mutation ; Tumor Suppressor Protein p53/genetics
SCR Disease Name:
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł:
A Novel Serum 4-microRNA Signature for Lung Cancer Detection.
Autorzy:
Nadal E; 1] Section of Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan [2] Department of Medical Oncology, Thoracic Oncology Multidisciplinary Unit, Catalan Institute of Oncology, L'Hospitalet, Barcelona, Spain.
Truini A; 1] Section of Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan [2] Lung Cancer Unit, IRCCS AOU San Martino-IST National Institute for Cancer Research, Genova, Italy.
Nakata A; Division of Systems Biomedical Technology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan.
Lin J; Section of Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Reddy RM; Section of Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Chang AC; Section of Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Ramnath N; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Gotoh N; Division of Systems Biomedical Technology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan.
Beer DG; Section of Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Chen G; Section of Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
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Źródło:
Scientific reports [Sci Rep] 2015 Jul 23; Vol. 5, pp. 12464. Date of Electronic Publication: 2015 Jul 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor/*blood
Carcinoma, Non-Small-Cell Lung/*blood
Carcinoma, Non-Small-Cell Lung/*diagnosis
Lung Neoplasms/*blood
Lung Neoplasms/*diagnosis
MicroRNAs/*blood
Aged ; Biomarkers, Tumor/genetics ; Carcinoma, Non-Small-Cell Lung/genetics ; Female ; Humans ; Lung Neoplasms/genetics ; Male ; MicroRNAs/classification ; MicroRNAs/genetics ; Reproducibility of Results ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
MAP3K3 expression in tumor cells and tumor-infiltrating lymphocytes is correlated with favorable patient survival in lung cancer.
Autorzy:
He Y; University of Guangzhou Chinese Medicine, Guangzhou, China.
Wang L; Guangxi Medical University, Nanning, China.
Liu W; The First People's Hospital of Yunnan Province, Kunming, China.
Zhong J; Xinjiang Medical University, Xinjiang, China.
Bai S; Xinjiang Medical University, Xinjiang, China.
Wang Z; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Thomas DG; Department of Pathology, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Lin J; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Reddy RM; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Ramnath N; Division of Medical Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Carrott PW; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Lynch WR; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Orringer MB; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Chang AC; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Beer DG; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
Chen G; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, 48109, United States.
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Źródło:
Scientific reports [Sci Rep] 2015 Jun 19; Vol. 5, pp. 11471. Date of Electronic Publication: 2015 Jun 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression*
Lung Neoplasms/*genetics
Lung Neoplasms/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
Lymphocytes, Tumor-Infiltrating/*metabolism
MAP Kinase Kinase Kinase 3/*genetics
Adenocarcinoma/genetics ; Adenocarcinoma/immunology ; Adenocarcinoma/metabolism ; Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adenocarcinoma of Lung ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cyclin E/genetics ; Epithelial-Mesenchymal Transition/genetics ; Female ; G1 Phase Cell Cycle Checkpoints/genetics ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Gene Silencing ; Glycogen Synthase Kinase 3/metabolism ; Glycogen Synthase Kinase 3 beta ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; MAP Kinase Kinase Kinase 3/metabolism ; Male ; Oncogene Proteins/genetics ; Prognosis ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/genetics ; Signal Transduction ; Transforming Growth Factor beta/genetics ; Transforming Growth Factor beta/metabolism ; cdc25 Phosphatases/genetics
Czasopismo naukowe
Tytuł:
The landscape of long noncoding RNAs in the human transcriptome.
Autorzy:
Iyer MK; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, Ann Arbor, Michigan, USA.
Niknafs YS; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Cellular and Molecular Biology, University of Michigan, Ann Arbor, Michigan, USA.
Malik R; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Singhal U; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, USA.
Sahu A; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Hosono Y; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Barrette TR; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Prensner JR; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Evans JR; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
Zhao S; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
Poliakov A; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Cao X; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, USA.
Dhanasekaran SM; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Wu YM; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Robinson DR; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Beer DG; 1] Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA. [2] Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Feng FY; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA. [3] Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.
Iyer HK; Department of Statistics, Colorado State University, Fort Collins, Colorado, USA.
Chinnaiyan AM; 1] Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, Ann Arbor, Michigan, USA. [3] Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA. [4] Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, USA. [5] Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan, USA. [6] Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.
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Źródło:
Nature genetics [Nat Genet] 2015 Mar; Vol. 47 (3), pp. 199-208. Date of Electronic Publication: 2015 Jan 19.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Transcriptome*
RNA, Long Noncoding/*genetics
Cell Line ; Cell Line, Tumor ; Gene Expression ; Humans ; Neoplasms/genetics ; Sequence Analysis, RNA/methods
Czasopismo naukowe
Tytuł:
Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.
Autorzy:
Zhang Y; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
Calado R; National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Rao M; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
Hong JA; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
Meeker AK; Departments of Pathology and Oncology, Johns Hopkins University of Medicine, Baltimore, Maryland, United States of America.
Dumitriu B; National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Atay S; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
McCormick PJ; Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, Maryland, United States of America.
Garfield SH; Laboratory of Experimental Carcinogenesis, National Cancer Institute, Bethesda, Maryland, United States of America.
Wangsa D; Section of Cancer Genomics, National Cancer Institute, Bethesda, Maryland, United States of America.
Padilla-Nash HM; Section of Cancer Genomics, National Cancer Institute, Bethesda, Maryland, United States of America.
Burkett S; Comparative Molecular Cytogenetics Core Facility, National Cancer Institute, Frederick, Maryland, United States of America.
Zhang M; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
Kunst TF; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
Peterson NR; National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Xi S; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
Inchauste S; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
Altorki NK; Department of Thoracic Surgery, Weill Cornell Medical Center, New York, New York, United States of America.
Casson AG; Department of Surgery, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Beer DG; Section of Thoracic Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
Harris CC; Laboratory of Human Carcinogenesis, National Cancer Institute, Bethesda, Maryland, United States of America.
Ried T; Section of Cancer Genomics, National Cancer Institute, Bethesda, Maryland, United States of America.
Young NS; National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Schrump DS; Thoracic Surgery Section, Thoracic and GI Oncology Branch; National Cancer Institute, Bethesda, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Jul 01; Vol. 9 (7), pp. e101010. Date of Electronic Publication: 2014 Jul 01 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Gene Expression Regulation, Enzymologic*
Gene Expression Regulation, Neoplastic*
Mutation, Missense*
Telomere Homeostasis*
Esophageal Neoplasms/*enzymology
Neoplasm Proteins/*biosynthesis
Telomerase/*biosynthesis
Amino Acid Substitution ; Animals ; Cell Line, Tumor ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/pathology ; Female ; Humans ; Male ; Mice ; Mice, Nude ; Neoplasm Proteins/genetics ; RNA/biosynthesis ; RNA/genetics ; RNA, Neoplasm/biosynthesis ; RNA, Neoplasm/genetics ; Telomerase/genetics ; Telomere/enzymology ; Telomere/genetics
Czasopismo naukowe
Tytuł:
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.
Autorzy:
Dulak AM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Stojanov P
Peng S
Lawrence MS
Fox C
Stewart C
Bandla S
Imamura Y
Schumacher SE
Shefler E
McKenna A
Carter SL
Cibulskis K
Sivachenko A
Saksena G
Voet D
Ramos AH
Auclair D
Thompson K
Sougnez C
Onofrio RC
Guiducci C
Beroukhim R
Zhou Z
Lin L
Lin J
Reddy R
Chang A
Landrenau R
Pennathur A
Ogino S
Luketich JD
Golub TR
Gabriel SB
Lander ES
Beer DG
Godfrey TE
Getz G
Bass AJ
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Źródło:
Nature genetics [Nat Genet] 2013 May; Vol. 45 (5), pp. 478-86. Date of Electronic Publication: 2013 Mar 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma/*genetics
Biomarkers, Tumor/*genetics
Esophageal Neoplasms/*genetics
Exome/*genetics
Genome, Human/*genetics
Mutation/*genetics
Chromosome Mapping ; Gene Rearrangement ; High-Throughput Nucleotide Sequencing ; Humans ; Neoplasm Invasiveness
Czasopismo naukowe
Tytuł:
Epidermal growth factor receptor tyrosine kinase defines critical prognostic genes of stage I lung adenocarcinoma.
Autorzy:
Yamauchi M; Division of Systems Biomedical Technology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan.
Yamaguchi R
Nakata A
Kohno T
Nagasaki M
Shimamura T
Imoto S
Saito A
Ueno K
Hatanaka Y
Yoshida R
Higuchi T
Nomura M
Beer DG
Yokota J
Miyano S
Gotoh N
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (9), pp. e43923. Date of Electronic Publication: 2012 Sep 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma/*genetics
Adenocarcinoma/*metabolism
ErbB Receptors/*metabolism
Lung Neoplasms/*genetics
Lung Neoplasms/*metabolism
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Cell Line, Tumor ; Computational Biology/methods ; Drug Resistance, Neoplasm/genetics ; Epidermal Growth Factor/pharmacology ; ErbB Receptors/antagonists & inhibitors ; Gefitinib ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Neoplasm Staging ; Prognosis ; Quinazolines/pharmacology ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: an international validation study.
Autorzy:
Bryant CM; Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.
Albertus DL
Kim S
Chen G
Brambilla C
Guedj M
Arima C
Travis WD
Yatabe Y
Takahashi T
Brambilla E
Beer DG
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Źródło:
PloS one [PLoS One] 2010 Jul 22; Vol. 5 (7), pp. e11712. Date of Electronic Publication: 2010 Jul 22.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma/*classification
Adenocarcinoma/*metabolism
Lung Neoplasms/*classification
Lung Neoplasms/*metabolism
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Cluster Analysis ; Humans ; Logistic Models ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Signal Transduction/genetics ; Signal Transduction/physiology ; Survival Analysis
Czasopismo naukowe
Tytuł:
An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer.
Autorzy:
Wang XS; Michigan Center for Translational Pathology, Ann Arbor, Michigan, USA.
Prensner JR
Chen G
Cao Q
Han B
Dhanasekaran SM
Ponnala R
Cao X
Varambally S
Thomas DG
Giordano TJ
Beer DG
Palanisamy N
Sartor MA
Omenn GS
Chinnaiyan AM
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Źródło:
Nature biotechnology [Nat Biotechnol] 2009 Nov; Vol. 27 (11), pp. 1005-11. Date of Electronic Publication: 2009 Nov 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Sequence Analysis, DNA*
Computational Biology/*methods
Gene Fusion/*genetics
Neoplasms/*genetics
Algorithms ; Animals ; Genes, Neoplasm/genetics ; Humans ; Molecular Sequence Data ; Point Mutation/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Recombination, Genetic/genetics ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.
Autorzy:
Shedden K
Taylor JM
Enkemann SA
Tsao MS
Yeatman TJ
Gerald WL
Eschrich S
Jurisica I
Giordano TJ
Misek DE
Chang AC
Zhu CQ
Strumpf D
Hanash S
Shepherd FA
Ding K
Seymour L
Naoki K
Pennell N
Weir B
Verhaak R
Ladd-Acosta C
Golub T
Gruidl M
Sharma A
Szoke J
Zakowski M
Rusch V
Kris M
Viale A
Motoi N
Travis W
Conley B
Seshan VE
Meyerson M
Kuick R
Dobbin KK
Lively T
Jacobson JW
Beer DG
Pokaż więcej
Corporate Authors:
Director's Challenge Consortium for the Molecular Classification of Lung Adenocarcinoma; Department of Statistics, 1085 South University, University of Michigan, Ann Arbor, Michigan 48109, USA.
Źródło:
Nature medicine [Nat Med] 2008 Aug; Vol. 14 (8), pp. 822-7. Date of Electronic Publication: 2008 Jul 20.
Typ publikacji:
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Profiling*
Gene Expression Regulation, Neoplastic*
Adenocarcinoma/*metabolism
Lung Neoplasms/*metabolism
Adenocarcinoma/mortality ; Aged ; Algorithms ; Female ; Humans ; Lung Neoplasms/mortality ; Male ; Middle Aged ; Models, Statistical ; Oligonucleotide Array Sequence Analysis ; ROC Curve ; Risk ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Doubly penalized buckley-james method for survival data with high-dimensional covariates.
Autorzy:
Wang S; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
Nan B
Zhu J
Beer DG
Pokaż więcej
Źródło:
Biometrics [Biometrics] 2008 Mar; Vol. 64 (1), pp. 132-40. Date of Electronic Publication: 2007 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Algorithms*
Proportional Hazards Models*
Survival Analysis*
Biomarkers, Tumor/*analysis
Gene Expression Profiling/*methods
Lung Neoplasms/*metabolism
Lung Neoplasms/*mortality
Oligonucleotide Array Sequence Analysis/*methods
Humans ; Risk Assessment/methods ; Risk Factors ; Survival Rate
Czasopismo naukowe
Tytuł:
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk.
Autorzy:
Schulmann K; Division of Gastroenterology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Sterian A
Berki A
Yin J
Sato F
Xu Y
Olaru A
Wang S
Mori Y
Deacu E
Hamilton J
Kan T
Krasna MJ
Beer DG
Pepe MS
Abraham JM
Feng Z
Schmiegel W
Greenwald BD
Meltzer SJ
Pokaż więcej
Źródło:
Oncogene [Oncogene] 2005 Jun 09; Vol. 24 (25), pp. 4138-48.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Adenocarcinoma/*genetics
Barrett Esophagus/*genetics
Cyclin-Dependent Kinase Inhibitor p16/*genetics
DNA-Binding Proteins/*genetics
Esophageal Neoplasms/*genetics
Membrane Proteins/*genetics
Neoplasm Proteins/*genetics
Transcription Factors/*genetics
Cell Line, Tumor ; Core Binding Factor Alpha 3 Subunit ; DNA Methylation ; DNA, Neoplasm/genetics ; DNA, Neoplasm/isolation & purification ; Disease Progression ; Humans ; Polymerase Chain Reaction ; Promoter Regions, Genetic ; RNA, Neoplasm/genetics ; RNA, Neoplasm/isolation & purification ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Factors
Czasopismo naukowe

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