Skocz do pozycji: 1.

Tytuł:

Binimetinib in combination with nivolumab or nivolumab and ipilimumab in patients with previously treated microsatellite-stable metastatic colorectal cancer with RAS mutations in an open-label phase 1b/2 study.

Autorzy:

Elez E; Medical Oncology Department, Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Universitat Autònoma de Barcelona, Barcelona, Spain. .
Cubillo A; Centro Integral, Oncológico Clara Campal, HM CIOCC, Madrid, Spain.; Facultad HM Hospitales de Ciencias de La Salud UCJC, 28050, Madrid, Spain.
Alfonso PG; Medical Oncology Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Universidad Complutense, Madrid, Spain.
Middleton MR; Department of Oncology, NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Chau I; Gastrointestinal Unit, Royal Marsden Hospital, London & Surrey, UK.
Alkuzweny B; Formerly Pfizer, Inc, San Diego, CA, USA.
Alcasid A; Pfizer Inc, Collegeville, PA, USA.
Zhang X; Pfizer, Inc, New York, NY, USA.
Van Cutsem E; University Hospitals Gasthuisberg Leuven and KU Leuven, Leuven, Belgium.

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Źródło:

BMC cancer [BMC Cancer] 2024 Apr 11; Vol. 24 (1), pp. 446. Date of Electronic Publication: 2024 Apr 11.

Typ publikacji:

Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Clinical Trial, Phase I; Journal Article

MeSH Terms:

Nivolumab*/therapeutic use
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Benzimidazoles*
Humans ; Ipilimumab ; Mutation ; Microsatellite Repeats ; Antineoplastic Combined Chemotherapy Protocols/adverse effects

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 2.

Tytuł:

Effect of TRPV4 Antagonist GSK2798745 on Chlorine Gas-Induced Acute Lung Injury in a Swine Model.

Autorzy:

Vermillion MS; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Saari N; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Bray M; GSK, Collegeville, PA 19426, USA.
Nelson AM; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Bullard RL; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Rudolph K; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Gigliotti AP; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Brendler J; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Jantzi J; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Kuehl PJ; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
McDonald JD; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Burgert ME; GSK, Collegeville, PA 19426, USA.
Weber W; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.
Sucoloski S; GSK, Collegeville, PA 19426, USA.
Behm DJ; GSK, Collegeville, PA 19426, USA.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Apr 02; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 02.

Typ publikacji:

Journal Article

MeSH Terms:

Acute Lung Injury*/chemically induced
Acute Lung Injury*/drug therapy
Antineoplastic Agents*
Benzimidazoles*
Spiro Compounds*
Animals ; Swine ; Chlorine/toxicity ; TRPV Cation Channels ; Inflammation ; Oxygen

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 3.

Tytuł:

Coumarin linked to 2-phenylbenzimidazole derivatives as potent α-glucosidase inhibitors.

Autorzy:

Ganjeh MS; Department of Chemistry, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.
Mazlomifar A; Department of Chemistry, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran. .
Shahvelayti AS; Department of Chemistry, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.
Moghaddam SK; Department of Biology, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.

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Źródło:

Scientific reports [Sci Rep] 2024 Mar 28; Vol. 14 (1), pp. 7408. Date of Electronic Publication: 2024 Mar 28.

Typ publikacji:

Journal Article

MeSH Terms:

Glycoside Hydrolase Inhibitors*/pharmacology
Diabetes Mellitus, Type 2*/drug therapy
Benzimidazoles*
Humans ; Molecular Structure ; Structure-Activity Relationship ; alpha-Glucosidases/metabolism ; Molecular Docking Simulation ; Kinetics ; Coumarins/pharmacology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 4.

Tytuł:

Bacteria-mediated green synthesis of silver nanoparticles and their antifungal potentials against Aspergillus flavus.

Autorzy:

Bharose AA; Marathawada Agriculture University, Parbhani, M. S., India.
Hajare ST; College of Natural and Computational Sciences, Dilla University, Dilla, Ethiopia.
H P G; Department of Biotechnology, College of Agriculture, Junagadh Agricultural University, Junagadh, Gujarat, India.
Soni M; Dr D.Y Patil Vidyapeeth, Pune and Department of CSE, University Centre for Research & Development Chandigarh University, Mohali, Punjab, India.
Prajapati KK; Shri Krishna Pathology & ELISA Laboratory, Sumerpur, India.
Singh SC; Bilva Laboratories Pvt Ltd, BHU, Varanasi, India.
Upadhye V; Institute of Applied Sciences, Research & Development Cell, Parul University, Vadodara, Gujarat, India.

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Źródło:

PloS one [PLoS One] 2024 Mar 25; Vol. 19 (3), pp. e0297870. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Metal Nanoparticles*/chemistry
Fungicides, Industrial*
Benzimidazoles*
Carbamates*
Antifungal Agents/pharmacology ; Aspergillus flavus ; Silver/pharmacology ; Silver/chemistry ; Aspergillus ; Bacteria ; Plant Extracts/chemistry ; Spectroscopy, Fourier Transform Infrared ; Anti-Bacterial Agents/chemistry ; Microbial Sensitivity Tests

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 5.

Tytuł:

Regulation of Cell Cycle Progression through RB Phosphorylation by Nilotinib and AT-9283 in Human Melanoma A375P Cells.

Autorzy:

Pham TM; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Ahmed M; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Lai TH; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Bahar ME; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Hwang JS; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Maulidi RF; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Ngo QN; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Kim DR; Department of Biochemistry and Convergence Medical Science, Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Mar 03; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 03.

Typ publikacji:

Journal Article

MeSH Terms:

Melanoma*
Benzimidazoles*
Urea/*analogs & derivatives
Humans ; Imatinib Mesylate ; Phosphorylation ; Fusion Proteins, bcr-abl/genetics ; Tyrosine Kinase Inhibitors ; Pyrimidines/pharmacology ; Protein Kinase Inhibitors/pharmacology ; Cell Division

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 6.

Tytuł:

Long-term in vitro monitoring of AAV-transduction efficiencies in real-time with Hoechst 33342.

Autorzy:

Hu X; Institute of Ophthalmology, University Eye Hospital, Hannover Medical School, Hannover, Germany.
Meister R; Institute of Ophthalmology, University Eye Hospital, Hannover Medical School, Hannover, Germany.
Tode J; Institute of Ophthalmology, University Eye Hospital, Hannover Medical School, Hannover, Germany.
Framme C; Institute of Ophthalmology, University Eye Hospital, Hannover Medical School, Hannover, Germany.
Fuchs H; Institute of Ophthalmology, University Eye Hospital, Hannover Medical School, Hannover, Germany.

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Źródło:

PloS one [PLoS One] 2024 Mar 01; Vol. 19 (3), pp. e0298173. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Cell Nucleus*
Coloring Agents*
Benzimidazoles*
Dependovirus/genetics ; Microscopy, Fluorescence

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 7.

Tytuł:

Comparative efficacy and safety of Sofosbuvir/Velpatasvir and Danoprevir for the treatment of chronic hepatitis C: the real-world data in China.

Autorzy:

Zhou Y; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China.
Liang M; Department of Infectious disease, The First people's hospital of Foshan, Foshan City, Guangdong Province, China.
Li Y; Department of General Practice, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou City, Guangdong Province, China.
Chen X; Department of Infectious Diseases, Yangjiang Public Health Hospital, Yangjiang City, Guangdong Province, China.
Yang J; Clinical Medicine Department of Southwest Medical University, Luzhou City, Sichuan Province, China.
Bai H; Department of Infectious disease, The First people's hospital of Foshan, Foshan City, Guangdong Province, China.
Long Y; Department of Infectious Diseases, The Eighth Hospital of Guangzhou Medical University, Guangzhou City, Guangdong Province, China.
Zhang X; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China.
Lin C; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China. .

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Źródło:

BMC gastroenterology [BMC Gastroenterol] 2024 Feb 14; Vol. 24 (1), pp. 73. Date of Electronic Publication: 2024 Feb 14.

Typ publikacji:

Comparative Study; Journal Article

MeSH Terms:

Benzimidazoles*
Benzopyrans*
Carbamates*
Cyclopropanes*
Drug Combinations*
Hepatitis C*/drug therapy
Hepatitis C, Chronic*/genetics
Isoindoles*
Lactams, Macrocyclic*
Proline*/analogs & derivatives
Sulfonamides*
Humans ; Antiviral Agents/adverse effects ; China ; Genotype ; Hepacivirus/genetics ; Heterocyclic Compounds, 4 or More Rings/adverse effects ; Liver Cirrhosis/drug therapy ; Retrospective Studies ; Ribavirin/adverse effects ; Sofosbuvir/adverse effects ; Treatment Outcome

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 8.

Tytuł:

Relationship between Medication-Related Osteonecrosis of the Jaw and CDK4/6 Inhibitors in Breast Cancer.

Autorzy:

Senín LD; Hospital Pharmacy, Juan Ramón Jiménez University Hospital, 21005 Huelva, Spain.
Pancorbo DM; Department of Medical Oncology, Juan Ramón Jiménez University Hospital, 21005 Huelva, Spain.
Garcés MYR; Department of Medical Oncology, Riotinto Hospital, 21660 Huelva, Spain.
Santos-Rubio MD; Hospital Pharmacy, Juan Ramón Jiménez University Hospital, 21005 Huelva, Spain.
Calero JB; Department of Medical Oncology, Juan Ramón Jiménez University Hospital, 21005 Huelva, Spain.

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Źródło:

Current oncology (Toronto, Ont.) [Curr Oncol] 2024 Jan 01; Vol. 31 (1), pp. 250-259. Date of Electronic Publication: 2024 Jan 01.

Typ publikacji:

Observational Study; Multicenter Study; Journal Article

MeSH Terms:

Breast Neoplasms*/drug therapy
Osteonecrosis*/chemically induced
Aminopyridines*
Benzimidazoles*
Humans ; Female ; Denosumab/adverse effects ; Prospective Studies ; Retrospective Studies ; Cyclin-Dependent Kinase 4

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 9.

Tytuł:

Azilsartan improves doxorubicin-induced cardiotoxicity via inhibiting oxidative stress, proinflammatory pathway, and apoptosis.

Autorzy:

Al-Chlaihawi M; Department of Pharmacy, Kufa Technical Institute, Al-Furat Al-Awsat Technical University, Najaf, Iraq.
Janabi A; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Kufa, Najaf, Iraq.

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Źródło:

Journal of medicine and life [J Med Life] 2023 Dec; Vol. 16 (12), pp. 1783-1788.

Typ publikacji:

Journal Article

MeSH Terms:

Cardiotoxicity*/drug therapy
Cardiotoxicity*/etiology
Cardiotoxicity*/prevention & control
Myocardium*/metabolism
Benzimidazoles*
Oxadiazoles*
Rats ; Male ; Animals ; Tumor Necrosis Factor-alpha/metabolism ; Dimethyl Sulfoxide/metabolism ; Dimethyl Sulfoxide/pharmacology ; Doxorubicin/toxicity ; Doxorubicin/metabolism ; Oxidative Stress ; Apoptosis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 10.

Tytuł:

Efficacy and safety of veliparib plus chemotherapy for the treatment of lung cancer: A systematic review of clinical trials.

Autorzy:

Daei Sorkhabi A; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Fazlollahi A; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Sarkesh A; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Aletaha R; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Feizi H; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mousavi SE; Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Nejadghaderi SA; Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Sullman MJM; Department of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.; Department of Social Sciences, University of Nicosia, Nicosia, Cyprus.
Kolahi AA; Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Safiri S; Clinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.; Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

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Źródło:

PloS one [PLoS One] 2023 Sep 08; Vol. 18 (9), pp. e0291044. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023).

Typ publikacji:

Systematic Review; Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Benzimidazoles*/adverse effects
Lung Neoplasms*/drug therapy
Humans ; Healthy Volunteers ; Poly(ADP-ribose) Polymerases ; Randomized Controlled Trials as Topic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 11.

Tytuł:

A Review of Approaches to the Metallic and Non-Metallic Synthesis of Benzimidazole (BnZ) and Their Derivatives for Biological Efficacy.

Autorzy:

Patel M; School of Sciences, P P Savani University, NH 8, GETCO, Near Biltech, Dhamdod, Kosamba, Surat 394125, Gujarat, India.
Avashthi G; School of Sciences, P P Savani University, NH 8, GETCO, Near Biltech, Dhamdod, Kosamba, Surat 394125, Gujarat, India.
Gacem A; Department of Physics, Faculty of Sciences, University 20 Août 1955 Skikda, Skikda 21000, Algeria.
Alqahtani MS; Radiological Sciences Department, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia.; Bioimaging Unit, Space Research Centre, Michael Atiyah Building, University of Leicester, Leicester LE1 7RH, UK.
Park HK; Department of Pediatrics, Hanyang University College of Medicine, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea.
Jeon BH; Department of Earth Resources and Environmental Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Jul 18; Vol. 28 (14). Date of Electronic Publication: 2023 Jul 18.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Benzimidazoles*/chemical synthesis
Benzimidazoles*/chemistry
Benzimidazoles*/pharmacology
Anti-Inflammatory Agents*/chemical synthesis
Anti-Inflammatory Agents*/chemistry
Anti-Inflammatory Agents*/pharmacology
Anti-Infective Agents*
Structure-Activity Relationship ; Benzene/chemistry ; Imidazoles/chemistry ; Catalysis ; Metals/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 12.

Tytuł:

Comparison of Homo-Polyimide Films Derived from Two Isomeric Bis-Benzimidazole Diamines.

Autorzy:

Lian M; Shandong Engineering Laboratory for Clean Utilization of Chemical Resources, Weifang University of Science and Technology, Weifang 262700, China.
Zheng F; School of Chemical Science and Engineering, Tongji University, Siping Road 1239, Shanghai 200092, China.
Meng L; Shandong Engineering Laboratory for Clean Utilization of Chemical Resources, Weifang University of Science and Technology, Weifang 262700, China.
Zhao F; Shandong Engineering Laboratory for Clean Utilization of Chemical Resources, Weifang University of Science and Technology, Weifang 262700, China.
Liu J; Shandong Engineering Laboratory for Clean Utilization of Chemical Resources, Weifang University of Science and Technology, Weifang 262700, China.
Song J; Shandong Engineering Laboratory for Clean Utilization of Chemical Resources, Weifang University of Science and Technology, Weifang 262700, China.
Lu Q; Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Jun 21; Vol. 28 (13). Date of Electronic Publication: 2023 Jun 21.

Typ publikacji:

Journal Article

MeSH Terms:

Benzimidazoles*
Aniline Compounds*
Humans ; Diamines ; Fever

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 13.

Tytuł:

Investigation of Excited-State Intramolecular Proton Transfer and Structural Dynamics in Bis-Benzimidazole Derivative (BBM).

Autorzy:

Xie J; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Wang Z; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhu R; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Jiang J; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Weng TC; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Ren Y; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Han S; Key Lab of Colloid and Interface Chemistry, Ministry of Education, Shandong University, Jinan 250100, China.
Huang Y; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Liu W; School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.; STU and SIOM Joint Laboratory for Superintense Lasers and the Applications, Shanghai 201210, China.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 May 29; Vol. 24 (11). Date of Electronic Publication: 2023 May 29.

Typ publikacji:

Journal Article

MeSH Terms:

Protons*
Benzimidazoles*/chemistry
Models, Molecular ; Isomerism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 14.

Tytuł:

New benzimidazole derivative compounds with in vitro fasciolicidal properties.

Autorzy:

Valderas-García E; Departamento Sanidad Animal, Instituto de Ganadería de Montaña, CSIC-Universidad de León, Grulleros, 24346, León, Spain.; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana S/N, 24071, León, Spain.
Castilla-Gómez de Agüero V; Departamento Sanidad Animal, Instituto de Ganadería de Montaña, CSIC-Universidad de León, Grulleros, 24346, León, Spain.; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana S/N, 24071, León, Spain.
González Del Palacio L; Departamento Sanidad Animal, Instituto de Ganadería de Montaña, CSIC-Universidad de León, Grulleros, 24346, León, Spain.; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana S/N, 24071, León, Spain.
Galli G; Departamento de Ciencias Biomédicas, Facultad de Veterinaria, Universidad de León, Campus de Vegazana S/N, 24071, León, Spain.
Escala N; Departamento de Ciencias Farmacéuticas: Química Farmacéutica, Facultad de Farmacia, Universidad de Salamanca, CIETUS, IBSAL, 37007, Salamanca, Spain.
Ruiz-Somacarrera M; Departamento Sanidad Animal, Instituto de Ganadería de Montaña, CSIC-Universidad de León, Grulleros, 24346, León, Spain.; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana S/N, 24071, León, Spain.
González-Warleta M; Laboratorio de Parasitología, Centro de Investigacións Agrarias de Mabegondo, AGACAL-Xunta de Galicia, Abegondo, 15318, A Coruña, Spain.
Del Olmo E; Departamento de Ciencias Farmacéuticas: Química Farmacéutica, Facultad de Farmacia, Universidad de Salamanca, CIETUS, IBSAL, 37007, Salamanca, Spain.
Balaña-Fouce R; Departamento de Ciencias Biomédicas, Institute of Biomedicine (IBIOMED), Universidad de León, 24071, León, Spain.
Martínez-Valladares M; Departamento Sanidad Animal, Instituto de Ganadería de Montaña, CSIC-Universidad de León, Grulleros, 24346, León, Spain. .

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Źródło:

Parasites & vectors [Parasit Vectors] 2024 Apr 03; Vol. 17 (1), pp. 173. Date of Electronic Publication: 2024 Apr 03.

Typ publikacji:

Journal Article

MeSH Terms:

Anthelmintics*/pharmacology
Anthelmintics*/therapeutic use
Fascioliasis*/parasitology
Fasciola hepatica*
Animals ; Humans ; Benzimidazoles/pharmacology ; Benzimidazoles/therapeutic use ; Antinematodal Agents/therapeutic use

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 15.

Tytuł:

Research Progress on Benzimidazole Fungicides: A Review.

Autorzy:

Bai S; Guizhou Industry Polytechnic College, Guiyang 550008, China.; School of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, China.; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
Zhang M; School of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, China.
Tang S; Guizhou Industry Polytechnic College, Guiyang 550008, China.
Li M; Guizhou Industry Polytechnic College, Guiyang 550008, China.
Wu R; Guizhou Industry Polytechnic College, Guiyang 550008, China.
Wan S; Guizhou Industry Polytechnic College, Guiyang 550008, China.
Chen L; School of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, China.
Wei X; School of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, China.
Li F; School of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, China.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2024 Mar 08; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 08.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Fungicides, Industrial*/pharmacology
Benzimidazoles/pharmacology ; Benzimidazoles/metabolism ; Carbamates/pharmacology ; Thiophanate ; Anti-Bacterial Agents

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 16.

Tytuł:

Synthesis and Biological Evaluation of Novel Amino and Amido Substituted Pentacyclic Benzimidazole Derivatives as Antiproliferative Agents.

Autorzy:

Perin N; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Gulin M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Kos M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Persoons L; KU Leuven, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute, 3000 Leuven, Belgium.
Daelemans D; KU Leuven, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute, 3000 Leuven, Belgium.
Fabijanić I; Ruđer Bošković Institute, Division of Organic Chemistry and Biochemistry, Bijenička cesta 54, HR-10000 Zagreb, Croatia.
Stojković MR; Ruđer Bošković Institute, Division of Organic Chemistry and Biochemistry, Bijenička cesta 54, HR-10000 Zagreb, Croatia.
Hranjec M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents*/chemistry
Humans ; Structure-Activity Relationship ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Benzimidazoles/chemistry ; Cell Proliferation ; Molecular Structure

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 17.

Tytuł:

Synthesis, Molecular Docking, Molecular Dynamic Simulation Studies, and Antitubercular Activity Evaluation of Substituted Benzimidazole Derivatives.

Autorzy:

Thapa, Shankar (AUTHOR)
Biradar, Mahalakshmi Suresha (AUTHOR)
Nargund, Shachindra L. (AUTHOR)
Ahmad, Iqrar (AUTHOR)
Agrawal, Mohit (AUTHOR)
Patel, Harun (AUTHOR)
Lamsal, Ashish (AUTHOR)

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Źródło:

Advances in Pharmacological & Pharmaceutical Sciences. 3/28/2024, Vol. 2024, p1-14. 14p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 18.

Tytuł:

Self-Assembled Molecular Complexes of 1,10-Phenanthroline and 2-Aminobenzimidazoles: Synthesis, Structure Investigations, and Cytotoxic Properties.

Autorzy:

Anichina, Kameliya (AUTHOR)
Kaloyanov, Nikolay (AUTHOR)
Zasheva, Diana (AUTHOR)
Rusew, Rusi (AUTHOR)
Nikolova, Rositsa (AUTHOR)
Yancheva, Denitsa (AUTHOR)
Bakov, Ventsislav (AUTHOR)
Georgiev, Nikolai (AUTHOR)

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Źródło:

Molecules. Feb2024, Vol. 29 Issue 3, p583. 15p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 19.

Tytuł:

Safety, pharmacokinetics and efficacy of selumetinib in Chinese adult and paediatric patients with neurofibromatosis type 1 and inoperable plexiform neurofibromas: The primary analysis of a phase 1 open-label study.

Autorzy:

Wang Z; Shanghai Ninth People's Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China.
Zhang X; Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China.
Li C; AstraZeneca Global R&D (China) Co. Ltd., Shanghai, China.
Liu Y; AstraZeneca Global R&D (China) Co. Ltd., Shanghai, China.
Ge X; AstraZeneca Global R&D (China) Co. Ltd., Shanghai, China.
Zhao J; AstraZeneca Global R&D (China) Co. Ltd., Shanghai, China.
Yuan X; Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China.
Li Q; Shanghai Ninth People's Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China.

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Źródło:

Clinical and translational medicine [Clin Transl Med] 2024 Mar; Vol. 14 (3), pp. e1589.

Typ publikacji:

Clinical Trial, Phase I; Letter; Research Support, Non-U.S. Gov't

MeSH Terms:

Neurofibroma, Plexiform*/drug therapy
Neurofibromatosis 1*/drug therapy
Adult ; Humans ; Child ; Benzimidazoles ; China

Raport

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 20.

Tytuł:

Gorse (Ulex europeaus) wastes with 5,6-dimethyl benzimidazole supplementation can support growth of vitamin B12 producing commensal gut microbes.

Autorzy:

Iyer A; Rowett Institute, University of Aberdeen, Aberdeen, Scotland.
Soto Martín EC; Institue of Medical Sciences, University of Aberdeen, Aberdeen, Scotland.
Cameron GA; Rowett Institute, University of Aberdeen, Aberdeen, Scotland.
Louis P; Rowett Institute, University of Aberdeen, Aberdeen, Scotland.
Duncan SH; Rowett Institute, University of Aberdeen, Aberdeen, Scotland.
Bestwick CS; Rowett Institute, University of Aberdeen, Aberdeen, Scotland.
Russell WR; Rowett Institute, University of Aberdeen, Aberdeen, Scotland.

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Źródło:

PloS one [PLoS One] 2024 Feb 29; Vol. 19 (2), pp. e0290052. Date of Electronic Publication: 2024 Feb 29 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Ulex*
Gastrointestinal Microbiome*
Humans ; Vitamin B 12 ; Benzimidazoles ; Carbon ; Dietary Supplements

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 21.

Tytuł:

DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target.

Autorzy:

Chen M; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China.; Department of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, People's Republic of China.
Zhang S; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China.
Wang F; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China.
He J; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China.
Jiang W; Department of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, People's Republic of China. .
Zhang L; Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China. .

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Źródło:

Journal of translational medicine [J Transl Med] 2024 Feb 27; Vol. 22 (1), pp. 209. Date of Electronic Publication: 2024 Feb 27.

Typ publikacji:

Journal Article

MeSH Terms:

Adenocarcinoma*
Adenocarcinoma of Lung*/drug therapy
Adenocarcinoma of Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Urea*/analogs & derivatives
Humans ; Benzimidazoles ; Neoplasm Proteins ; Prognosis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 22.

Tytuł:

Comparative overall survival of CDK4/6 inhibitors in combination with endocrine therapy in advanced breast cancer.

Autorzy:

Kappel C; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Elliott MJ; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Kumar V; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Nadler MB; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Desnoyers A; Hôpital Charles-Lemoyne, Greenfield Park, QC, Canada.
Amir E; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada. .; Princess Margaret Cancer Centre, 610 University Ave, 700U, 7-721, Toronto, ON, M5G 2M9, Canada. .

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Źródło:

Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3129. Date of Electronic Publication: 2024 Feb 07.

Typ publikacji:

Journal Article; Meta-Analysis; Systematic Review

MeSH Terms:

Antineoplastic Combined Chemotherapy Protocols*/adverse effects
Breast Neoplasms*/drug therapy
Female ; Humans ; Aminopyridines ; Benzimidazoles ; Cyclin-Dependent Kinase 4 ; Cyclin-Dependent Kinase 6 ; Cyclin-Dependent Kinase Inhibitor Proteins ; Neutropenia/chemically induced ; Purines ; Clinical Trials, Phase III as Topic ; Randomized Controlled Trials as Topic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 23.

Tytuł:

A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma-Application to a Pharmacokinetic Study.

Autorzy:

Hefnawy MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.; Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Alanazi MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Al-Hossaini AM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alnasser AI; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
El-Azab AS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Jardan YAB; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Attwa MW; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
El-Gendy MA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Dec 22; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 22.

Typ publikacji:

Journal Article

MeSH Terms:

Tandem Mass Spectrometry*/methods
Carbamates*/blood
Carbamates*/pharmacokinetics
Sulfonamides*/blood
Sulfonamides*/pharmacokinetics
Benzimidazoles*/blood
Benzimidazoles*/pharmacokinetics
Melanoma*/drug therapy
Antineoplastic Combined Chemotherapy Protocols*/blood
Antineoplastic Combined Chemotherapy Protocols*/pharmacokinetics
Animals ; Rats ; Chromatography, Liquid/methods ; Proto-Oncogene Proteins B-raf/metabolism ; Reproducibility of Results

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 24.

Tytuł:

Rational design and synthesis of 2-(1 H -indazol-6-yl)-1 H -benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants.

Autorzy:

Im D; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.
Jun J; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.
Baek J; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.
Kim H; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.
Kang D; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.
Bae H; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.
Cho H; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.
Hah JM; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.; Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, Korea.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 472-486.

Typ publikacji:

Journal Article

MeSH Terms:

Drug Design*
Benzimidazoles/*pharmacology
Protein Kinase Inhibitors/*pharmacology
fms-Like Tyrosine Kinase 3/*antagonists & inhibitors
Benzimidazoles/chemical synthesis ; Benzimidazoles/chemistry ; Crystallography, X-Ray ; Dose-Response Relationship, Drug ; Humans ; Models, Molecular ; Molecular Structure ; Mutation ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Structure-Activity Relationship ; fms-Like Tyrosine Kinase 3/genetics ; fms-Like Tyrosine Kinase 3/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 25.

Tytuł:

Synthesis and structure-activity relationships for some novel diflapolin derivatives with benzimidazole subunit.

Autorzy:

Vieider L; Department of Pharmaceutical Chemistry, Center for Chemistry and Biomedicine, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria.
Zoeller E; Department of Pharmaceutical Chemistry, Center for Chemistry and Biomedicine, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria.
Romp E; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, University of Jena, Jena, Germany.
Schoenthaler M; Department of Pharmaceutical Chemistry, Center for Chemistry and Biomedicine, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria.
Hernández-Olmos V; Branch for Translation Medicine and Pharmacology TMP, Frauenhofer Institute for Molecular Biology and Applied Ecology IME, Frankfurt am Main, Germany.
Temml V; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University Salzburg, Salzburg, Austria.
Hasenoehrl T; Department of Pharmaceutical Chemistry, Center for Chemistry and Biomedicine, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria.
Schuster D; Department of Pharmaceutical Chemistry, Center for Chemistry and Biomedicine, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria.; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University Salzburg, Salzburg, Austria.
Werz O; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, University of Jena, Jena, Germany.
Garscha U; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, University of Greifswald, Greifswald, Germany.
Matuszczak B; Department of Pharmaceutical Chemistry, Center for Chemistry and Biomedicine, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1752-1764.

Typ publikacji:

Journal Article

MeSH Terms:

Benzimidazoles*/pharmacology
Epoxide Hydrolases*
5-Lipoxygenase-Activating Proteins/metabolism ; Enzyme Inhibitors/pharmacology ; Lipoxygenase Inhibitors/pharmacology ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 26.

Tytuł:

Identification of new benzimidazole-triazole hybrids as anticancer agents: multi-target recognition, in vitro and in silico studies.

Autorzy:

Othman DIA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Hamdi A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Tawfik SS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Elgazar AA; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Mostafa AS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2166037.

Typ publikacji:

Journal Article

MeSH Terms:

Vascular Endothelial Growth Factor Receptor-2*
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Molecular Structure ; Structure-Activity Relationship ; Molecular Docking Simulation ; Triazoles/pharmacology ; Cell Proliferation ; ErbB Receptors/metabolism ; Benzimidazoles/pharmacology ; Benzimidazoles/chemistry ; Drug Screening Assays, Antitumor ; Protein Kinase Inhibitors/pharmacology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 27.

Tytuł:

Polymorphism of Bis(benzimidazole)bis(thiocyanato- N)cobalt(II) and Its Relevance to Studies of the Chief Color Test for Cocaine.

Autorzy:

Burks, Raychelle (AUTHOR)
Noa, Francoise M. Amombo (AUTHOR)
Öhrström, Lars (AUTHOR)

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Źródło:

Inorganics. Jan2024, Vol. 12 Issue 1, p28. 13p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 28.

Tytuł:

Compatibility of benzimidazole and benzothiazole derivatives towards poly-A.poly-T DNA.

Autorzy:

Sur, Souvik
Khan, Uzma

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Źródło:

Indian Journal of Chemistry (0019-5103). Jan2024, Vol. 63 Issue 1, p65-71. 7p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 29.

Tytuł:

Synthesis, molecular docking, molinspiration and anti-oxidant studies of novel Nethylbenzimidazolylisoxazole derivatives.

Autorzy:

Harsha, J.
Reji, T. F. Abbs Fen

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Źródło:

Indian Journal of Chemistry (0019-5103). Dec2023, Vol. 62 Issue 12, p1247-1251. 5p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 30.

Tytuł:

The Efficient CO2 Fixation Catalyzed by Fe-Based Catalyst for Synthesizing Benzimidazoles.

Autorzy:

Zhang, Luping (AUTHOR)
Tu, Xuewei (AUTHOR)
Han, Weihang (AUTHOR)
Chen, Liangchen (AUTHOR)
Chen, Yutong (AUTHOR)
Zheng, Hui (AUTHOR)

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Źródło:

Catalysis Letters. Nov2023, Vol. 153 Issue 11, p3383-3391. 9p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 31.

Tytuł:

Visible Light Promotes Cascade Trifluoromethylation/Cyclization, Leading to Trifluoromethylated Polycyclic Quinazolinones, Benzimidazoles and Indoles.

Autorzy:

Ma R; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Ren Y; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Deng Z; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Wang KH; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Wang J; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Huang D; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Hu Y; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.; State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Lv X; Shanghai Sinofluoro Chemicals Co., Ltd., Shanghai 201321, China.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Dec 01; Vol. 27 (23). Date of Electronic Publication: 2022 Dec 01.

Typ publikacji:

Journal Article

MeSH Terms:

Indoles*
Benzimidazoles*
Quinazolinones ; Catalysis ; Light

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 32.

Tytuł:

In Silico ADME and Toxicity Prediction of Benzimidazole Derivatives and Its Cobalt Coordination Compounds. Synthesis, Characterization and Crystal Structure.

Autorzy:

Raducka A; Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Łódź, Poland.
Świątkowski M; Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Łódź, Poland.
Gobis K; Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Gen. Hallera 107, 80-416 Gdańsk, Poland.
Szymański P; Department of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.; Department of Radiobiology and Radiation Protection, Military Institute of Hygiene and Epidemiology, 4 Kozielska St., 01-163 Warsaw, Poland.
Czylkowska A; Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Łódź, Poland.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Nov 18; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 18.

Typ publikacji:

Journal Article

MeSH Terms:

Cobalt*/toxicity
Cobalt*/chemistry
Benzimidazoles*/chemistry
Ligands ; Tissue Distribution ; Pharmaceutical Preparations

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 33.

Tytuł:

Synthesis, and spectroscopic and structural characterization of three new styrylquinoline-benzimidazole hybrids.

Autorzy:

Ardila DM; Laboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678, Bucaramanga, Colombia.
Rodríguez DF; Laboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678, Bucaramanga, Colombia.
Palma A; Laboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678, Bucaramanga, Colombia.
Díaz Costa I; Departamento de Química Inorgánica y Orgánica, Universidad de Jaén, 23071 Jaén, Spain.
Cobo J; Departamento de Química Inorgánica y Orgánica, Universidad de Jaén, 23071 Jaén, Spain.
Glidewell C; School of Chemistry, University of St Andrews, Fife, KY16 9ST, United Kingdom.

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Źródło:

Acta crystallographica. Section C, Structural chemistry [Acta Crystallogr C Struct Chem] 2022 Nov 01; Vol. 78 (Pt 11), pp. 671-680. Date of Electronic Publication: 2022 Oct 25.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Benzimidazoles*/chemistry
Quinolines*
Hydrogen Bonding ; Crystallography, X-Ray

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 34.

Tytuł:

C-NMR Chemical Shifts in 1,3-Benzazoles as a Tautomeric Ratio Criterion.

Autorzy:

García-Báez EV; Laboratorio de Química Supramolecular y Nanociencias, Instituto Politécnico Nacional-UPIBI, Av. Acueducto s/n, Barrio la Laguna Ticomán, Mexico City 07340, Mexico.
Padilla-Martínez II; Laboratorio de Química Supramolecular y Nanociencias, Instituto Politécnico Nacional-UPIBI, Av. Acueducto s/n, Barrio la Laguna Ticomán, Mexico City 07340, Mexico.
Cruz A; Laboratorio de Química Supramolecular y Nanociencias, Instituto Politécnico Nacional-UPIBI, Av. Acueducto s/n, Barrio la Laguna Ticomán, Mexico City 07340, Mexico.
Rosales-Hernández MC; Laboratorio de Biofísica y Biocatálisis, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Salvador Díaz Mirón s/n, Casco de Santo Tomás, Mexico City 11340, Mexico.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Sep 23; Vol. 27 (19). Date of Electronic Publication: 2022 Sep 23.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Benzimidazoles*/chemistry
Thiones*
Ligands ; Pyridines ; Pyrroles

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 35.

Tytuł:

Docking study, molecular dynamic, synthesis, anti-α-glucosidase assessment, and ADMET prediction of new benzimidazole-Schiff base derivatives.

Autorzy:

Azizian H; Department of Medicinal Chemistry, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran.
Pedrood K; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Moazzam A; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Valizadeh Y; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Khavaninzadeh K; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Zamani A; Faculty of Chemistry, University of Mazandaran, Babolsar, Iran.
Mohammadi-Khanaposhtani M; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. .
Mojtabavi S; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Faramarzi MA; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Hosseini S; Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sarrafi Y; Faculty of Chemistry, University of Mazandaran, Babolsar, Iran.
Adibi H; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Larijani B; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Rastegar H; Cosmetic Products Research Center, Iranian Food and Drug Administration, MOHE, Tehran, Iran.
Mahdavi M; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. .

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Źródło:

Scientific reports [Sci Rep] 2022 Sep 01; Vol. 12 (1), pp. 14870. Date of Electronic Publication: 2022 Sep 01.

Typ publikacji:

Journal Article

MeSH Terms:

Benzimidazoles*/chemistry
Benzimidazoles*/pharmacology
Hyperglycemia*/drug therapy
Hyperglycemia*/metabolism
Schiff Bases*/chemistry
Schiff Bases*/pharmacology
alpha-Glucosidases*/drug effects
alpha-Glucosidases*/metabolism
Catalytic Domain ; Diabetes Mellitus, Type 2/drug therapy ; Glycoside Hydrolase Inhibitors/chemistry ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Spectroscopy, Fourier Transform Infrared ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 36.

Tytuł:

Parbendazole as a promising drug for inducing differentiation of acute myeloid leukemia cells with various subtypes.

Autorzy:

Matsuo H; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan. .
Inagami A; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito Y; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito N; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Iyoda S; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Harata Y; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Higashitani M; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shoji K; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tanaka M; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Noura M; Department of Integrated Health Sciences, Division of Cellular and Genetic Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Mikami T; Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kato I; Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takita J; Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nakahata T; Department of Fundamental Cell Technology, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
Adachi S; Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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Źródło:

Communications biology [Commun Biol] 2024 Jan 24; Vol. 7 (1), pp. 123. Date of Electronic Publication: 2024 Jan 24.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Anthelmintics*
Humans ; Animals ; Mice ; Cell Differentiation ; Benzimidazoles ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 37.

Tytuł:

Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies.

Autorzy:

Youssif BGM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
Morcoss MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Nahda University, Beni-Suef 62513, Egypt.
Bräse S; Institute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.
Abdel-Aziz M; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Abdel-Rahman HM; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Badr University in Assiut (BUA), Assiut 71536, Egypt.
Abou El-Ella DA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy Ain Shams University, Cairo 11566, Egypt.
Abdelhafez ESMN; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2024 Jan 16; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 16.

Typ publikacji:

Journal Article

MeSH Terms:

Proto-Oncogene Proteins B-raf*/genetics
Antineoplastic Agents*/pharmacology
Humans ; Molecular Docking Simulation ; Antinematodal Agents ; Cell Line, Tumor ; Benzimidazoles/pharmacology ; ErbB Receptors

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 38.

Tytuł:

Characterization of the Effect of N -(2-Methoxyphenyl)-1-methyl-1 H -benzimidazol-2-amine, Compound 8, against Leishmania mexicana and Its In Vivo Leishmanicidal Activity.

Autorzy:

Nieto-Meneses R; Departamento de Parasitología, ENCB-Instituto Politécnico Nacional, Mexico City 11340, Mexico.; Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias-UMAE Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.
Castillo R; Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Hernández-Campos A; Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Nogueda-Torres B; Departamento de Parasitología, ENCB-Instituto Politécnico Nacional, Mexico City 11340, Mexico.
López-Villegas EO; Central de Microscopia, ENCB-Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Moreno-Rodríguez A; Facultad de Ciencias Químicas, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca 68120, Mexico.
Matadamas-Martínez F; Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias-UMAE Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.
Yépez-Mulia L; Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias-UMAE Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Jan 04; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 04.

Typ publikacji:

Journal Article

MeSH Terms:

Leishmania mexicana*
Leishmaniasis, Cutaneous*/drug therapy
Humans ; Apoptosis ; Arginase ; Benzimidazoles/pharmacology ; Amines

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 39.

Tytuł:

Maribavir: Mechanism of action, clinical, and translational science.

Autorzy:

Sun K; Quantitative Clinical Pharmacology, Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Fournier M; Clinical Sciences, Rare Genetics & Hematology Therapeutic Area Unit, Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Sundberg AK; Clinical Sciences, Rare Genetics & Hematology Therapeutic Area Unit, Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Song IH; Quantitative Clinical Pharmacology, Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.

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Źródło:

Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13696.

Typ publikacji:

Journal Article; Review; Research Support, Non-U.S. Gov't

MeSH Terms:

Antiviral Agents*
Cytomegalovirus Infections*/chemically induced
Cytomegalovirus Infections*/drug therapy
Dichlororibofuranosylbenzimidazole/*analogs & derivatives
Humans ; Translational Science, Biomedical ; Benzimidazoles

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 40.

Tytuł:

Existence of Quantum Pharmacology in Sartans: Evidence in Isolated Rabbit Iliac Arteries.

Autorzy:

Gadanec LK; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.
Swiderski J; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.
Apostolopoulos V; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.; Immunology Program, Australian Institute for Musculoskeletal Science (AIMSS), Melbourne, VIC 3021, Australia.
Kelaidonis K; NewDrug PC, Patras Science Park, 26 504 Patras, Greece.
Vidali VP; Institute of Nanoscience and Nanotechnology, National Centre for Scientific Research 'Demokritos', Ag. Paraskevi, 153 41 Athens, Greece.
Canko A; Institute of Nanoscience and Nanotechnology, National Centre for Scientific Research 'Demokritos', Ag. Paraskevi, 153 41 Athens, Greece.
Moore GJ; Pepmetics Inc., 772 Murphy Place, Victoria, BC V6Y 3H4, Canada.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Matsoukas JM; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.; NewDrug PC, Patras Science Park, 26 504 Patras, Greece.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.; Department of Chemistry, University of Patras, 265 04 Patras, Greece.
Zulli A; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Dec 16; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 16.

Typ publikacji:

Journal Article

MeSH Terms:

Angiotensin II Type 1 Receptor Blockers*/therapeutic use
Hypertension*/drug therapy
Rabbits ; Male ; Animals ; Telmisartan/pharmacology ; Angiotensin-Converting Enzyme 2/pharmacology ; Angiotensin Receptor Antagonists/pharmacology ; Iliac Artery ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Benzimidazoles/therapeutic use ; Tetrazoles/pharmacology ; Tetrazoles/therapeutic use ; Blood Pressure

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 41.

Tytuł:

New spiro-indeno[1,2- b ]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights.

Autorzy:

Barakat A; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Alshahrani S; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Al-Majid AM; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Alamary AS; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Haukka M; Department of Chemistry, University of Jyväskylä, Jyväskylä, Finland.
Abu-Serie MM; Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Egypt.
Domingo LR; Department of Organic Chemistry, University of Valencia, Burjassot, Valencia, Spain.
Ashraf S; Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
Ul-Haq Z; Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
Nafie MS; Department of Chemistry, College of Sciences, University of Sharjah, Sharjah, UAE.; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt.
Teleb M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2281260. Date of Electronic Publication: 2023 Nov 23.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents*/chemistry
Carcinoma, Non-Small-Cell Lung*/drug therapy
Cyclin-Dependent Kinase 2*/antagonists & inhibitors
Lung Neoplasms*/drug therapy
Humans ; Benzimidazoles/pharmacology ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Protein Kinase Inhibitors/chemistry ; Quinoxalines

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 42.

Tytuł:

A growing threat: Investigating the high incidence of benzimidazole fungicides resistance in Iranian Botrytis cinerea isolates.

Autorzy:

Mobasher Amini M; Department of Plant Protection, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran.
Mirzaei S; Department of Plant Protection, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran.
Heidari A; Department of Pesticide Research, Iranian Research Institute of Plant Protection, Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran.

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Źródło:

PloS one [PLoS One] 2023 Nov 21; Vol. 18 (11), pp. e0294530. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2023).

Typ publikacji:

Journal Article

MeSH Terms:

Fungicides, Industrial*/pharmacology
Iran ; Incidence ; Drug Resistance, Fungal/genetics ; Plant Diseases ; Botrytis ; Benzimidazoles/pharmacology

SCR Organism:

Botrytis cinerea

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 43.

Tytuł:

Recent progress of research on anti-tumor agents using benzimidazole as the structure unit.

Autorzy:

Wu K; Institute of Pharmacy and Pharmacology, Hunan Province, Cooperative Innovation Center for Molecular Target New Drug Study, College of Pharmacy, Hengyang Medical School, University of South China, Hengyang, China.
Peng X; Institute of Pharmacy and Pharmacology, Hunan Province, Cooperative Innovation Center for Molecular Target New Drug Study, College of Pharmacy, Hengyang Medical School, University of South China, Hengyang, China.
Chen M; Department of Pharmacy, the first People's Hospital, Yueyang, China.
Li Y; Institute of Pharmacy and Pharmacology, Hunan Province, Cooperative Innovation Center for Molecular Target New Drug Study, College of Pharmacy, Hengyang Medical School, University of South China, Hengyang, China.
Tang G; Institute of Pharmacy and Pharmacology, Hunan Province, Cooperative Innovation Center for Molecular Target New Drug Study, College of Pharmacy, Hengyang Medical School, University of South China, Hengyang, China.
Peng J; Institute of Pharmacy and Pharmacology, Hunan Province, Cooperative Innovation Center for Molecular Target New Drug Study, College of Pharmacy, Hengyang Medical School, University of South China, Hengyang, China.
Peng Y; School of Electrical and Automation Engineering, East China Jiaotong University, Nanchang, China.
Cao X; Institute of Pharmacy and Pharmacology, Hunan Province, Cooperative Innovation Center for Molecular Target New Drug Study, College of Pharmacy, Hengyang Medical School, University of South China, Hengyang, China.

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Źródło:

Chemical biology & drug design [Chem Biol Drug Des] 2022 May; Vol. 99 (5), pp. 736-757. Date of Electronic Publication: 2022 Feb 09.

Typ publikacji:

Journal Article; Review; Research Support, Non-U.S. Gov't

MeSH Terms:

Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Benzimidazoles*/chemistry
Benzimidazoles*/pharmacology
Drug Design ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 44.

Tytuł:

Further Quinolizidine Derivatives as Antiarrhythmic Agents- 3.

Autorzy:

Tasso, Bruno (AUTHOR)
Mattioli, Laura Beatrice (AUTHOR)
Tonelli, Michele (AUTHOR)
Boido, Vito (AUTHOR)
Chiarini, Alberto (AUTHOR)
Sparatore, Fabio (AUTHOR)
Budriesi, Roberta (AUTHOR)

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Źródło:

Molecules. Oct2023, Vol. 28 Issue 19, p6916. 13p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 45.

Tytuł:

SYNTHETIC APPROACHES OF BENZIMIDAZOLE DERIVATIVES: A REVIEW.

Autorzy:

Padhy, Gopal Krishna
Panda, Jagadeesh
Patro, Chandra Sekhar
Raul, Saroj Kumar
Behera, Ajaya Kumar

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Źródło:

Rasayan Journal of Chemistry. Oct-Dec2023, Vol. 16 Issue 4, p2009-2018. 10p.

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 46.

Tytuł:

Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling.

Autorzy:

Najafi S; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.
Barasa L; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.
Huang SY; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.
Yoganathan S; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA. .
Perron JC; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA. .

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Źródło:

Scientific reports [Sci Rep] 2022 Jul 15; Vol. 12 (1), pp. 12146. Date of Electronic Publication: 2022 Jul 15.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Benzimidazoles*/pharmacology
Smad Proteins*/metabolism
Bone Morphogenetic Protein 2/metabolism ; Bone Morphogenetic Protein 2/pharmacology ; Bone Morphogenetic Protein 4/metabolism ; Bone Morphogenetic Protein 7/metabolism ; Bone Morphogenetic Protein Receptors ; Bone Morphogenetic Proteins/metabolism ; Carrier Proteins ; Phosphatidylinositol 3-Kinases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 47.

Tytuł:

Correlated studies of photoluminescence, vibrational spectroscopy and mass spectrometry concerning the pantoprazole sodium photodegradation.

Autorzy:

Baibarac M; National Institute of Materials Physics, Laboratory of Optical Processes in Nanostructured Materials, Atomistilor Street 405A, POB MG 7, 077125, Bucharest, Romania. .
Paraschiv M; National Institute of Materials Physics, Laboratory of Optical Processes in Nanostructured Materials, Atomistilor Street 405A, POB MG 7, 077125, Bucharest, Romania.
Cercel R; National Institute of Materials Physics, Laboratory of Optical Processes in Nanostructured Materials, Atomistilor Street 405A, POB MG 7, 077125, Bucharest, Romania.
Smaranda I; National Institute of Materials Physics, Laboratory of Optical Processes in Nanostructured Materials, Atomistilor Street 405A, POB MG 7, 077125, Bucharest, Romania.
Bartha C; National Institute of Materials Physics, Laboratory of Magnetism and Superconductivity, Atomistilor Street 405A, POB MG-7, R077125, Bucharest, Romania.
Trandabat A; SC Intelectro Iasi SRL, 700470, Iasi, Romania.

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Źródło:

Scientific reports [Sci Rep] 2022 Jun 09; Vol. 12 (1), pp. 9515. Date of Electronic Publication: 2022 Jun 09.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Benzimidazoles*
Sodium*
Mass Spectrometry ; Oxygen ; Pantoprazole ; Photolysis ; Spectroscopy, Fourier Transform Infrared

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 48.

Tytuł:

Synthesis and Structure-Activity Relationship Studies of Benzimidazole-4,7-dione-Based P2X3 Receptor Antagonists as Novel Anti-Nociceptive Agents.

Autorzy:

Bae J; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea.
Kim YO; Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Han X; Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Yoon MH; Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Kim WM; Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
Kim YC; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea.; School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Feb 16; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 16.

Typ publikacji:

Journal Article

MeSH Terms:

Analgesics/*chemistry
Analgesics/*pharmacology
Benzimidazoles/*chemistry
Benzimidazoles/*pharmacology
Purinergic P2X Receptor Antagonists/*chemistry
Purinergic P2X Receptor Antagonists/*pharmacology
Analgesics/chemical synthesis ; Animals ; Benzimidazoles/chemical synthesis ; Chemistry Techniques, Synthetic ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Drug Monitoring ; Humans ; Mice ; Molecular Structure ; Purinergic P2X Receptor Antagonists/chemical synthesis ; Rats ; Small Molecule Libraries ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 49.

Tytuł:

Preclinical in vitro screening of newly synthesised amidino substituted benzimidazoles and benzothiazoles.

Autorzy:

Racané L; Department of Applied Chemistry, Faculty of Textile Technology, University of Zagreb, Zagreb, Croatia.
Cindrić M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.
Zlatar I; Pharmacology in vitro, Fidelta Ltd, Zagreb, Croatia.
Kezele T; DMPK, Fidelta Ltd, Zagreb, Croatia.
Milić A; DMPK, Fidelta Ltd, Zagreb, Croatia.
Brajša K; Pharmacology in vitro, Fidelta Ltd, Zagreb, Croatia.
Hranjec M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 163-174.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Benzimidazoles/*pharmacology
Benzothiazoles/*pharmacology
Cell Proliferation/*drug effects
A549 Cells ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/metabolism ; Benzimidazoles/chemical synthesis ; Benzimidazoles/metabolism ; Benzothiazoles/chemical synthesis ; Benzothiazoles/metabolism ; Blood Proteins/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; DNA, Neoplasm/metabolism ; Doxorubicin/pharmacology ; Drug Screening Assays, Antitumor ; High-Throughput Screening Assays ; Humans ; Inhibitory Concentration 50 ; Piperidines/pharmacology ; Protein Binding ; Quinazolines/pharmacology ; Solubility ; Staurosporine/pharmacology ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 50.

Tytuł:

Mapping resistance-associated anthelmintic interactions in the model nematode Caenorhabditis elegans.

Autorzy:

Rehborg EG; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Microbiology Doctoral Training Program, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Wheeler NJ; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Zamanian M; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

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Źródło:

PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Oct 26; Vol. 17 (10), pp. e0011705. Date of Electronic Publication: 2023 Oct 26 (Print Publication: 2023).

Typ publikacji:

Journal Article

MeSH Terms:

Anthelmintics*/therapeutic use
Nematoda*
Animals ; Humans ; Caenorhabditis elegans ; Benzimidazoles/pharmacology ; Drug Interactions ; Drug Resistance

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły