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Wyszukujesz frazę ""Betacoronavirus"" wg kryterium: Temat


Tytuł :
The nucleocapsid protein of zoonotic betacoronaviruses is an attractive target for antiviral drug discovery.
Autorzy :
Lang Y; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA.
Chen K; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA.
Li Z; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA.
Li H; Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA; Department of Biomedical Sciences, School of Public Health, University at Albany, 1 University Place, Rensselaer, NY 12144, USA. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 118754. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Discovery*
Antiviral Agents/*chemistry
Antiviral Agents/*pharmacology
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Coronavirus Nucleocapsid Proteins/*metabolism
Animals ; Betacoronavirus/physiology ; COVID-19/drug therapy ; Coronavirus Nucleocapsid Proteins/antagonists & inhibitors ; Coronavirus Nucleocapsid Proteins/chemistry ; Host-Pathogen Interactions/drug effects ; Humans ; Middle East Respiratory Syndrome Coronavirus/drug effects ; Models, Molecular ; Molecular Targeted Therapy ; Phosphoproteins/antagonists & inhibitors ; Phosphoproteins/chemistry ; Phosphoproteins/metabolism ; Protein Interaction Maps/drug effects ; SARS-CoV-2/drug effects
Czasopismo naukowe
Tytuł :
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice.
Autorzy :
Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. .
Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
De la Cruz G; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
West A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Atochina-Vasserman EN; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Lindesmith LC; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Pardi N; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Barr M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Li D; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Yount B; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Weissman D; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Montgomery SA; Department of Laboratory Medicine and Pathology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. .
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Źródło :
Science (New York, N.Y.) [Science] 2021 Aug 27; Vol. 373 (6558), pp. 991-998. Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*immunology
COVID-19 Vaccines/*immunology
Coronavirus Infections/*prevention & control
Spike Glycoprotein, Coronavirus/*immunology
Vaccines, Synthetic/*immunology
Viral Vaccines/*immunology
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Betacoronavirus/physiology ; COVID-19/prevention & control ; Coronavirus Infections/immunology ; Cross Protection ; Cytokines/blood ; Female ; Immunity, Heterologous ; Immunogenicity, Vaccine ; Liposomes ; Lung/pathology ; Lung/virology ; Mice ; Mice, Inbred BALB C ; Nanoparticles ; Protein Domains ; Recombinant Fusion Proteins ; SARS Virus/immunology ; SARS Virus/physiology ; SARS-CoV-2/immunology ; SARS-CoV-2/physiology ; Severe Acute Respiratory Syndrome/prevention & control ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Virus Replication
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Outbreak of equine coronavirus infection among riding horses in Tokyo, Japan.
Autorzy :
Kambayashi Y; Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi, 329-0412, Japan.
Bannai H; Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi, 329-0412, Japan.
Tsujimura K; Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi, 329-0412, Japan.
Hirama A; Racehorse Clinic, Tokyo Racecourse, Japan Racing Association, 1-1 Hiyoshi-cho, Fuchu, Tokyo, 183-0024, Japan.
Ohta M; Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi, 329-0412, Japan.
Nemoto M; Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi, 329-0412, Japan. Electronic address: .
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Źródło :
Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2021 Aug; Vol. 77, pp. 101668. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus 1*
Coronavirus Infections*/epidemiology
Coronavirus Infections*/veterinary
Horse Diseases*/epidemiology
Animals ; Disease Outbreaks/veterinary ; Horses ; Japan/epidemiology ; Tokyo
Czasopismo naukowe
Tytuł :
A comparative review of pathogenesis and host innate immunity evasion strategies among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV).
Autorzy :
Noor R; Department of Life Sciences (DLS), School of Environment and Life Sciences (SELS), Independent University, Bangladesh (IUB), Plot 16, Block B, Aftabuddin Ahmed Road, Bashundhara, Dhaka, 1229, Bangladesh. .
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Źródło :
Archives of microbiology [Arch Microbiol] 2021 Jul; Vol. 203 (5), pp. 1943-1951. Date of Electronic Publication: 2021 Mar 07.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Immune Evasion*
Betacoronavirus/*pathogenicity
Coronavirus Infections/*immunology
Coronavirus Infections/*virology
Betacoronavirus/classification ; Betacoronavirus/physiology ; Coronavirus Infections/epidemiology ; Cytokines/immunology ; Disease Progression ; Humans ; Immunity, Innate ; Species Specificity ; Virus Internalization
Czasopismo naukowe
Tytuł :
An application of slow feature analysis to the genetic sequences of coronaviruses and influenza viruses.
Autorzy :
Tsonis AA; Department of Mathematical Sciences, Atmospheric Sciences Group, University of Wisconsin-Milwaukee, Milwaukee, WI, 53201, USA. .; Hydrologic Research Center, San Diego, CA, 92127, USA. .
Wang G; Key Laboratory of Middle Atmosphere and Global Environment Observation (LAGEO), Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing, 100029, China.
Zhang L; Key Laboratory of Middle Atmosphere and Global Environment Observation (LAGEO), Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing, 100029, China.
Lu W; Key Laboratory of Middle Atmosphere and Global Environment Observation (LAGEO), Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing, 100029, China.
Kayafas A; Department of Biology and Center for Visual Sciences, Miami University, Oxford, OH, 45056, USA.
Del Rio-Tsonis K; Department of Biology and Center for Visual Sciences, Miami University, Oxford, OH, 45056, USA. .
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Źródło :
Human genomics [Hum Genomics] 2021 May 07; Vol. 15 (1), pp. 26. Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Genetic*
Betacoronavirus/*classification
Betacoronavirus/*genetics
Influenza A virus/*classification
Influenza A virus/*genetics
Betacoronavirus/physiology ; Coronavirus Infections/mortality ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Evolution, Molecular ; Humans ; Influenza A virus/physiology ; Influenza, Human/mortality ; Influenza, Human/transmission ; Influenza, Human/virology ; Sequence Analysis, DNA ; Species Specificity ; Time Factors
Czasopismo naukowe
Tytuł :
External validation of a clinical risk score to predict hospital admission and in-hospital mortality in COVID-19 patients.
Autorzy :
Halalau A; Internal Medicine Department, Beaumont Health, Royal Oak, MI, USA.; Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
Imam Z; Internal Medicine Department, Beaumont Health, Royal Oak, MI, USA.
Karabon P; Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
Mankuzhy N; Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
Shaheen A; Internal Medicine Department, Beaumont Health, Royal Oak, MI, USA.
Tu J; Internal Medicine Department, Beaumont Health, Royal Oak, MI, USA.; Oakland University William Beaumont School of Medicine, Rochester, MI, USA.; Clinical Informatics, Beaumont Health, Southfield, MI, USA.
Carpenter C; Internal Medicine Department, Beaumont Health, Royal Oak, MI, USA.; Oakland University William Beaumont School of Medicine, Rochester, MI, USA.; Section of Infectious Disease, Beaumont Health, Royal Oak, MI, USA.
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Źródło :
Annals of medicine [Ann Med] 2021 Dec; Vol. 53 (1), pp. 78-86. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Betacoronavirus*
Hospital Mortality*
Coronavirus Infections/*mortality
Critical Illness/*mortality
Pneumonia, Viral/*mortality
Adult ; Aged ; COVID-19 ; Cohort Studies ; Coronavirus Infections/therapy ; Critical Illness/therapy ; Databases, Factual ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/therapy ; Retrospective Studies ; Risk Assessment ; Risk Factors ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Structural Analysis of the OC43 Coronavirus 2'-O-RNA Methyltransferase.
Autorzy :
Dostalik P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Krafcikova P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Silhan J; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Kozic J; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Chalupska D; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Chalupsky K; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Boura E; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
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Źródło :
Journal of virology [J Virol] 2021 Jul 12; Vol. 95 (15), pp. e0046321. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*enzymology
Methyltransferases/*chemistry
Viral Proteins/*chemistry
Betacoronavirus/genetics ; Binding Sites ; Crystallography, X-Ray ; Methyltransferases/genetics ; Protein Conformation, alpha-Helical ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Coronavirus Receptors as Immune Modulators.
Autorzy :
Devarakonda CKV; Center for Vascular Biology, University of Connecticut School of Medicine, Farmington, CT 06030.
Meredith E; Center for Vascular Biology, University of Connecticut School of Medicine, Farmington, CT 06030.
Ghosh M; Center for Vascular Biology, University of Connecticut School of Medicine, Farmington, CT 06030.
Shapiro LH; Center for Vascular Biology, University of Connecticut School of Medicine, Farmington, CT 06030 .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Mar 01; Vol. 206 (5), pp. 923-929. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Immunomodulation*
Betacoronavirus/*classification
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Metalloproteases/*immunology
Receptors, Cell Surface/*immunology
Receptors, Coronavirus/*immunology
Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Betacoronavirus/metabolism ; Coronavirus Infections/virology ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/virology ; Humans ; Immunity ; Interleukin-6/immunology ; Virus Internalization
Czasopismo naukowe
Tytuł :
Mechanisms of Coronavirus Nsp1-Mediated Control of Host and Viral Gene Expression.
Autorzy :
Nakagawa K; Laboratory of Veterinary Microbiology, Joint Department of Veterinary Medicine, Gifu University, Gifu 501-1193, Japan.
Makino S; Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, TX 77555-1019, USA.; Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, TX 77555-1019, USA.; UTMB Center for Tropical Diseases, The University of Texas Medical Branch, Galveston, TX 77555-1019, USA.; Sealy Center for Vaccine Development, The University of Texas Medical Branch, Galveston, TX 77555-1019, USA.; Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, TX 77555-1019, USA.
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Źródło :
Cells [Cells] 2021 Feb 02; Vol. 10 (2). Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Betacoronavirus*/pathogenicity
Betacoronavirus*/physiology
Coronavirus Infections/*virology
RNA-Dependent RNA Polymerase/*physiology
Viral Nonstructural Proteins/*physiology
Animals ; Gene Expression Regulation ; Host Microbial Interactions ; Humans ; Mice ; RNA, Messenger/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
Porcine hemagglutinating encephalomyelitis virus induces atypical autophagy via opposite regulation of expression and nuclear translocation of transcription factor EB.
Autorzy :
Wang Z; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Song D; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Wang G; Jilin Academy of Animal Husbandry and Veterinary Medicine, Changchun, Jilin, China.
Li C; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Liu X; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Wang X; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Li Z; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Guan J; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Zhao K; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
He W; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Gao F; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Lan Y; Key Laboratory ofZoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2021 Apr; Vol. 255, pp. 109015. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus 1*
Gene Expression Regulation*
Autophagy/*physiology
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*metabolism
Lysosome-Associated Membrane Glycoproteins/*metabolism
Virus Replication/*physiology
Active Transport, Cell Nucleus ; Animals ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ; Cell Line ; Lysosome-Associated Membrane Glycoproteins/genetics ; Mechanistic Target of Rapamycin Complex 1/genetics ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mice ; Swine
Czasopismo naukowe
Tytuł :
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies.
Autorzy :
Wang C; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
van Haperen R; Department of Cell Biology, Erasmus Medical Center, Rotterdam, the Netherlands.; Harbour BioMed, Rotterdam, the Netherlands.
Gutiérrez-Álvarez J; Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.
Li W; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Okba NMA; Department of Viroscience, Erasmus Medical Center, Rotterdam, the Netherlands.
Albulescu I; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Widjaja I; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.; Merus N.V., Utrecht, the Netherlands.
van Dieren B; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Fernandez-Delgado R; Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.
Sola I; Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.
Hurdiss DL; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Daramola O; Cell Culture and Fermentation Sciences, Biopharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Grosveld F; Department of Cell Biology, Erasmus Medical Center, Rotterdam, the Netherlands.; Harbour BioMed, Rotterdam, the Netherlands.
van Kuppeveld FJM; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Haagmans BL; Department of Viroscience, Erasmus Medical Center, Rotterdam, the Netherlands.
Enjuanes L; Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.
Drabek D; Department of Cell Biology, Erasmus Medical Center, Rotterdam, the Netherlands.; Harbour BioMed, Rotterdam, the Netherlands.
Bosch BJ; Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 17; Vol. 12 (1), pp. 1715. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal, Humanized/*immunology
Betacoronavirus/*immunology
Epitopes/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Animals ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Viral/immunology ; Betacoronavirus/classification ; Camelus ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Cross Reactions ; Epitopes/chemistry ; Epitopes/genetics ; Humans ; Mice ; Protein Conformation ; Protein Subunits ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics
Czasopismo naukowe
Tytuł :
Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication.
Autorzy :
Adams LE; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Dinnon KH 3rd; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Hou YJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Heise MT; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA .; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Rapidly Emerging Antiviral Drug Discovery Initiative, University of North Carolina, Chapel Hill, North Carolina, USA.
Baric RS; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA .; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Rapidly Emerging Antiviral Drug Discovery Initiative, University of North Carolina, Chapel Hill, North Carolina, USA.
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Źródło :
MBio [mBio] 2021 Mar 16; Vol. 12 (2). Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Replication*
Angiotensin-Converting Enzyme 2/*chemistry
Angiotensin-Converting Enzyme 2/*metabolism
Betacoronavirus/*physiology
Amino Acid Sequence ; Angiotensin-Converting Enzyme 2/genetics ; Animals ; Betacoronavirus/metabolism ; Binding Sites ; COVID-19/virology ; Cell Line ; Coronavirus Infections/virology ; Host Specificity ; Humans ; Mice ; Models, Molecular ; Mutation ; Protein Binding ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; SARS-CoV-2/metabolism ; SARS-CoV-2/physiology ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism
Czasopismo naukowe
Tytuł :
Surveillance of Coronavirus Disease 2019 (COVID-19) Testing in Clinical Laboratories in Korea.
Autorzy :
Huh HJ; Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hong KH; Department of Laboratory Medicine, Seoul Medical Center, Seoul, Korea.
Kim TS; Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Song SH; Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Roh KH; Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Lee H; Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
Kwon GC; Department of Laboratory Medicine, College of Medicine, Chungnam National University, Daejeon, Korea.
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Źródło :
Annals of laboratory medicine [Ann Lab Med] 2021 Mar 01; Vol. 41 (2), pp. 225-229.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus/*genetics
Clinical Laboratory Services/*statistics & numerical data
Coronavirus Infections/*diagnosis
Pneumonia, Viral/*diagnosis
Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Envelope Proteins ; Coronavirus Infections/virology ; Humans ; Laboratories, Hospital ; Pandemics ; Pneumonia, Viral/virology ; RNA, Viral/genetics ; RNA, Viral/metabolism ; RNA-Dependent RNA Polymerase/genetics ; Real-Time Polymerase Chain Reaction ; Republic of Korea ; SARS-CoV-2 ; Viral Envelope Proteins/genetics ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
An overview of Betacoronaviruses-associated severe respiratory syndromes, focusing on sex-type-specific immune responses.
Autorzy :
Rahimi G; Department of Cellular and Molecular Biology, University of Esfahan, Esfahan, Iran.
Rahimi B; Department of Medical Biotechnology, Faculty of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.
Panahi M; Student Research Committee, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Abkhiz S; Department of Medical Biotechnology, Faculty of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.
Saraygord-Afshari N; Department of Medical Biotechnology, Faculty of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.
Milani M; Department of Medical Biotechnology, Faculty of Advanced Medical Sciences and Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
Alizadeh E; Drug Applied Research Center and Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 Mar; Vol. 92, pp. 107365. Date of Electronic Publication: 2021 Jan 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Betacoronavirus*
Coronavirus Infections/*immunology
Coronavirus Infections/*virology
Respiratory Tract Infections/*immunology
Respiratory Tract Infections/*virology
Antiviral Agents/therapeutic use ; Coronavirus Infections/drug therapy ; Female ; Humans ; Male ; Respiratory Tract Infections/drug therapy ; Sex Factors
Czasopismo naukowe
Tytuł :
Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19.
Autorzy :
Choudhary S; Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India.
Sreenivasulu K; Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India.
Mitra P; Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India.
Misra S; Department of Surgical Oncology, All India Institute of Medical Sciences, Jodhpur, India.
Sharma P; Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India.
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Źródło :
Annals of laboratory medicine [Ann Lab Med] 2021 Mar 01; Vol. 41 (2), pp. 129-138.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Variation*
Betacoronavirus/*genetics
Coronavirus Infections/*pathology
Pneumonia, Viral/*pathology
Angiotensin-Converting Enzyme 2 ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/virology ; Dipeptidyl Peptidase 4/genetics ; Dipeptidyl Peptidase 4/metabolism ; Disease Susceptibility ; Gene Expression ; Humans ; Pandemics ; Peptidyl-Dipeptidase A/chemistry ; Peptidyl-Dipeptidase A/genetics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
The analysis on the human protein domain targets and host-like interacting motifs for the MERS-CoV and SARS-CoV/CoV-2 infers the molecular mimicry of coronavirus.
Autorzy :
Martínez YA; Unidad de Investigación Biomédica de Zacatecas, Instituto Mexicano Del Seguro Social, Zacatecas, México.; Laboratorio de Inmunología y Biología Celular y Molecular, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
Guo X; Laboratorio de Biotecnología Genómica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa, México.
Portales-Pérez DP; Laboratorio de Inmunología y Biología Celular y Molecular, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
Rivera G; Laboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa, México.
Castañeda-Delgado JE; Unidad de Investigación Biomédica de Zacatecas, Instituto Mexicano Del Seguro Social, Zacatecas, México.; Cátedras-CONACYT, Unidad de Investigación Biomédica de Zacatecas, Instituto Mexicano Del Seguro Social, Zacatecas, México.
García-Pérez CA; Information and Communication Technology Department (ICT), Complex Systems, Helmholtz Zentrum München, Neuherberg, Germany.
Enciso-Moreno JA; Unidad de Investigación Biomédica de Zacatecas, Instituto Mexicano Del Seguro Social, Zacatecas, México.
Lara-Ramírez EE; Unidad de Investigación Biomédica de Zacatecas, Instituto Mexicano Del Seguro Social, Zacatecas, México.
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Źródło :
PloS one [PLoS One] 2021 Feb 17; Vol. 16 (2), pp. e0246901. Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*metabolism
Coronavirus Infections/*metabolism
Coronavirus Infections/*virology
Molecular Mimicry/*physiology
Protein Interaction Domains and Motifs/*immunology
Betacoronavirus/genetics ; COVID-19/metabolism ; COVID-19/virology ; Coronavirus Infections/genetics ; Databases, Genetic ; Host-Pathogen Interactions ; Humans ; Middle East Respiratory Syndrome Coronavirus/genetics ; Middle East Respiratory Syndrome Coronavirus/metabolism ; Protein Domains ; Protein Interaction Domains and Motifs/genetics ; Proteome ; SARS Virus/genetics ; SARS Virus/metabolism ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus.
Autorzy :
Al-Beltagi S; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Preda CA; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Goulding LV; The Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
James J; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Pu J; Key Laboratory of Animal Epidemiology, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China.
Skinner P; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Jiang Z; Key Laboratory of Animal Epidemiology, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China.
Wang BL; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Yang J; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Banyard AC; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Mellits KH; School of Biosciences, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Gershkovich P; School of Pharmacy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Hayes CJ; School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Nguyen-Van-Tam J; School of Medicine, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Brown IH; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Liu J; Key Laboratory of Animal Epidemiology, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China.
Chang KC; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
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Źródło :
Viruses [Viruses] 2021 Feb 03; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
Betacoronavirus/*drug effects
Coronavirus OC43, Human/*drug effects
Influenza A Virus, H1N1 Subtype/*drug effects
Respiratory Syncytial Virus, Human/*drug effects
SARS-CoV-2/*drug effects
Thapsigargin/*pharmacology
Animals ; Antiviral Agents/therapeutic use ; Betacoronavirus/physiology ; Cell Line ; Cell Line, Tumor ; Cells, Cultured ; Coronavirus OC43, Human/physiology ; Endoplasmic Reticulum Stress ; Humans ; Influenza A Virus, H1N1 Subtype/physiology ; Mice ; Microbial Sensitivity Tests ; Orthomyxoviridae Infections/drug therapy ; Orthomyxoviridae Infections/virology ; Respiratory Syncytial Virus, Human/physiology ; Ribavirin/pharmacology ; SARS-CoV-2/physiology ; Thapsigargin/therapeutic use ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Analyzing the spatial determinants of local Covid-19 transmission in the United States.
Autorzy :
Andersen LM; Department of Geography and Planning, Appalachian State University, USA. Electronic address: .
Harden SR; Department of Geography and Planning, Appalachian State University, USA.
Sugg MM Ph.D; Department of Geography and Planning, Appalachian State University, USA.
Runkle JD Ph.D; North Carolina Institute for Climate Studies, North Carolina State University, USA.
Lundquist TE; Department of Geography and Planning, Appalachian State University, USA.
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Feb 01; Vol. 754, pp. 142396. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus*
COVID-19*
Pneumonia, Viral*/epidemiology
Humans ; Pandemics ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Safety of Surgical Telehealth in the Outpatient and Inpatient Setting.
Autorzy :
Purnell S; Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street, Smith 16, Houston, TX 77030, USA.
Zheng F; Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street, Smith 16, Houston, TX 77030, USA. Electronic address: .
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Źródło :
The Surgical clinics of North America [Surg Clin North Am] 2021 Feb; Vol. 101 (1), pp. 109-119. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ambulatory Care*
Betacoronavirus*
Critical Care*
Postoperative Care*
Telemedicine*
Coronavirus Infections/*prevention & control
Pandemics/*prevention & control
Pneumonia, Viral/*prevention & control
COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Humans ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; SARS-CoV-2
Czasopismo naukowe

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