Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Beteck RM"" wg kryterium: Autor


Wyświetlanie 1-10 z 10
Tytuł:
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation.
Autorzy:
du Preez C; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Legoabe LJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Jordaan A; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory, South Africa.
Jesumoroti OJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Warner DF; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory, South Africa.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, South Africa.; Faculty of Health Sciences, Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), University of Cape Town, Rondebosch, South Africa.
Beteck RM; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2023 Mar; Vol. 101 (3), pp. 717-726. Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Curcumin*
Mycobacterium tuberculosis*
Antitubercular Agents/pharmacology ; Structure-Activity Relationship ; Microbial Sensitivity Tests
Czasopismo naukowe
Tytuł:
Assessment of the Activity of Decoquinate and Its Quinoline- O -Carbamate Derivatives against Toxoplasma gondii In Vitro and in Pregnant Mice Infected with T. gondii Oocysts.
Autorzy:
Ramseier J; Institute of Parasitology, Vetsuisse Faculty, Department of Infectious Diseases and Pathobiology, University of Bern, Länggass-Strasse 122, 3012 Bern, Switzerland.
Imhof D; Institute of Parasitology, Vetsuisse Faculty, Department of Infectious Diseases and Pathobiology, University of Bern, Länggass-Strasse 122, 3012 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Mittelstrasse 43, 3012 Bern, Switzerland.
Anghel N; Institute of Parasitology, Vetsuisse Faculty, Department of Infectious Diseases and Pathobiology, University of Bern, Länggass-Strasse 122, 3012 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Mittelstrasse 43, 3012 Bern, Switzerland.
Hänggeli K; Institute of Parasitology, Vetsuisse Faculty, Department of Infectious Diseases and Pathobiology, University of Bern, Länggass-Strasse 122, 3012 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Mittelstrasse 43, 3012 Bern, Switzerland.
Beteck RM; Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom 2520, South Africa.
Balmer V; Institute of Parasitology, Vetsuisse Faculty, Department of Infectious Diseases and Pathobiology, University of Bern, Länggass-Strasse 122, 3012 Bern, Switzerland.
Ortega-Mora LM; SALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.
Sanchez-Sanchez R; SALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.
Ferre I; SALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.
Haynes RK; Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom 2520, South Africa.
Hemphill A; Institute of Parasitology, Vetsuisse Faculty, Department of Infectious Diseases and Pathobiology, University of Bern, Länggass-Strasse 122, 3012 Bern, Switzerland.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Oct 22; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Carbamates*/chemistry
Antiprotozoal Agents/*pharmacology
Decoquinate/*pharmacology
Quinolines/*pharmacology
Toxoplasma/*drug effects
Toxoplasmosis, Animal/*drug therapy
Toxoplasmosis, Animal/*parasitology
Animals ; Antiprotozoal Agents/chemistry ; Decoquinate/analogs & derivatives ; Decoquinate/chemistry ; Disease Models, Animal ; Female ; Infectious Disease Transmission, Vertical/prevention & control ; Mice ; Molecular Structure ; Oocysts/drug effects ; Pregnancy ; Quinolines/chemistry ; Toxoplasma/ultrastructure
Czasopismo naukowe
Tytuł:
Chemical Classes Presenting Novel Antituberculosis Agents Currently in Different Phases of Drug Development: A 2010-2020 Review.
Autorzy:
Angula KT; Centre of Excellence for Pharmaceutical Sciences (Pharmacen), North-West University, Potchefstroom 2520, South Africa.
Legoabe LJ; Centre of Excellence for Pharmaceutical Sciences (Pharmacen), North-West University, Potchefstroom 2520, South Africa.
Beteck RM; Centre of Excellence for Pharmaceutical Sciences (Pharmacen), North-West University, Potchefstroom 2520, South Africa.
Pokaż więcej
Źródło:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2021 May 13; Vol. 14 (5). Date of Electronic Publication: 2021 May 13.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Tytuł:
Easy-To-Access Quinolone Derivatives Exhibiting Antibacterial and Anti-Parasitic Activities.
Autorzy:
Beteck RM; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.
Jordaan A; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa.
Seldon R; SAMRC Drug Discovery and Development Research Unit, University of Cape Town, Cape Town 7700, South Africa.
Laming D; Centre for Chemico- and Biomedicinal Research, Rhodes University, Makhanda 6140, South Africa.
Hoppe HC; Centre for Chemico- and Biomedicinal Research, Rhodes University, Makhanda 6140, South Africa.; Department of Biochemistry and Microbiology, Faculty of Science, Rhodes University, Makhanda 6140, South Africa.
Warner DF; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Cape Town 7925, South Africa.
Khanye SD; Centre for Chemico- and Biomedicinal Research, Rhodes University, Makhanda 6140, South Africa.; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Rhodes University, Makhanda 6140, South Africa.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 20; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 20.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Bacterial Agents/*pharmacology
Antiprotozoal Agents/*pharmacology
Quinolones/*pharmacology
Acinetobacter baumannii/drug effects ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Antiprotozoal Agents/chemical synthesis ; Antiprotozoal Agents/chemistry ; Dose-Response Relationship, Drug ; Microbial Sensitivity Tests ; Molecular Structure ; Parasitic Sensitivity Tests ; Plasmodium falciparum/drug effects ; Quinolones/chemical synthesis ; Quinolones/chemistry ; Staphylococcus aureus/drug effects ; Trypanosoma brucei brucei/drug effects
Czasopismo naukowe
Tytuł:
6-Nitro-1-benzylquinolones exhibiting specific antitubercular activity.
Autorzy:
Beteck RM; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Jordaan A; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory, South Africa.
Swart T; Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.
Van Der Kooy F; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Warner DF; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory, South Africa.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Rondebosch, South Africa.
Hoppe HC; Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown, South Africa.
Legoabe LJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2020 Dec; Vol. 96 (6), pp. 1387-1394. Date of Electronic Publication: 2020 Jul 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antitubercular Agents/*pharmacology
Quinolones/*pharmacology
Drug Screening Assays, Antitumor ; Gram-Positive Bacteria/drug effects ; HeLa Cells ; Humans ; Microbial Sensitivity Tests ; Spectrum Analysis/methods
Czasopismo naukowe
Tytuł:
Synthesis and evaluation of C3 substituted chalcone-based derivatives of 7-azaindole as protein kinase inhibitors.
Autorzy:
Qhobosheane MA; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Legoabe LJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Josselin B; Sorbonne Université, CNRS, UMR 8227, Integrative Biology of Marine Models Laboratory (LBI2M), Station Biologique de Roscoff, Roscoff Cedex, France.; Sorbonne Université, CNRS, FR2424, Plateforme de criblage KISSf (Kinase Inhibitor Specialized Screening facility), Station Biologique de Roscoff, Roscoff, France.
Bach S; Sorbonne Université, CNRS, UMR 8227, Integrative Biology of Marine Models Laboratory (LBI2M), Station Biologique de Roscoff, Roscoff Cedex, France.; Sorbonne Université, CNRS, FR2424, Plateforme de criblage KISSf (Kinase Inhibitor Specialized Screening facility), Station Biologique de Roscoff, Roscoff, France.
Ruchaud S; Sorbonne Université, CNRS, UMR 8227, Integrative Biology of Marine Models Laboratory (LBI2M), Station Biologique de Roscoff, Roscoff Cedex, France.
Beteck RM; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2020 Dec; Vol. 96 (6), pp. 1395-1407. Date of Electronic Publication: 2020 Aug 18.
Typ publikacji:
Journal Article
MeSH Terms:
Chalcones/*chemical synthesis
Chalcones/*pharmacology
Indoles/*pharmacology
Protein Kinase Inhibitors/*chemical synthesis
Protein Kinase Inhibitors/*pharmacology
Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Chalcones/chemistry ; Drug Design ; Humans ; Protein Kinase Inhibitors/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
An Update on Development of Small-Molecule Plasmodial Kinase Inhibitors.
Autorzy:
Moolman C; Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.
Sluis RV; Focus Area for Human Metabolomics, Biochemistry, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.
Beteck RM; Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.
Legoabe LJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 07; Vol. 25 (21). Date of Electronic Publication: 2020 Nov 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antimalarials/*pharmacology
Drug Discovery/*trends
Malaria/*drug therapy
Plasmodium/*drug effects
Protein Kinase Inhibitors/*pharmacology
Animals ; Calcium/metabolism ; Casein Kinase I/metabolism ; Culicidae ; Drug Design ; Drug Resistance ; Glycogen Synthase Kinase 3/metabolism ; Humans ; Imidazoles/pharmacology ; Inhibitory Concentration 50 ; Life Cycle Stages/drug effects ; MAP Kinase Signaling System ; Phosphotransferases/chemistry ; Plasmodium/enzymology ; Pyridines/pharmacology
Czasopismo naukowe
Tytuł:
New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis .
Autorzy:
Beteck RM; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Rhodes University, Grahamstown 6140, South Africa. .
Seldon R; Drug Discovery and Development Centre (H3-D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa. .
Jordaan A; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory 7925, South Africa. .
Warner DF; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory 7925, South Africa. .; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa. .; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory 7925, South Africa. .
Hoppe HC; Department of Biochemistry and Microbiology, Faculty of Science, Rhodes University, Grahamstown 6140, South Africa. .; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Laming D; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Khanye SD; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Rhodes University, Grahamstown 6140, South Africa. .; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 May 04; Vol. 24 (9). Date of Electronic Publication: 2019 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Infective Agents/*chemical synthesis
Mycobacterium tuberculosis/*drug effects
Plasmodium falciparum/*drug effects
Quinolones/*chemistry
Small Molecule Libraries/*chemical synthesis
Thiosemicarbazones/*chemistry
Animals ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Candy ; Drug Interactions ; HeLa Cells ; Humans ; Inhibitory Concentration 50 ; Malaria, Falciparum/drug therapy ; Molecular Structure ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Tuberculosis
Czasopismo naukowe
Tytuł:
Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity.
Autorzy:
Gumbo M; Faculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. .
Beteck RM; Faculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. .
Mandizvo T; Faculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. .
Seldon R; Drug Discovery and Development Centre (H3-D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa. .
Warner DF; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Rondebosch 7701, South Africa. .; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa. .
Hoppe HC; Faculty of Science, Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa. .; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Isaacs M; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Laming D; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Tam CC; Foodborne Toxin Detection and Prevention Research Unit, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA. .
Cheng LW; Foodborne Toxin Detection and Prevention Research Unit, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA. .
Liu N; Department of Biological Sciences, University of the Pacific, Stockton, CA 95211, USA. n_.
Land KM; Department of Biological Sciences, University of the Pacific, Stockton, CA 95211, USA. .
Khanye SD; Faculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. .; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2018 Aug 15; Vol. 23 (8). Date of Electronic Publication: 2018 Aug 15.
Typ publikacji:
Journal Article
MeSH Terms:
Amides/*chemical synthesis
Anti-Infective Agents/*chemical synthesis
Boron Compounds/*chemical synthesis
Cinnamates/*chemical synthesis
Amides/pharmacology ; Animals ; Anti-Infective Agents/pharmacology ; Boron Compounds/pharmacology ; Cell Survival/drug effects ; Cinnamates/pharmacology ; HeLa Cells ; Humans ; Mycobacterium tuberculosis/drug effects ; Small Molecule Libraries/chemical synthesis ; Structure-Activity Relationship ; Trichomonas vaginalis/drug effects ; Trypanocidal Agents/chemical synthesis ; Trypanocidal Agents/pharmacology ; Trypanosoma brucei brucei/drug effects ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł:
Recent progress in the development of anti-malarial quinolones.
Autorzy:
Beteck RM
Smit FJ
Haynes RK
N'Da DD; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. .
Pokaż więcej
Źródło:
Malaria journal [Malar J] 2014 Aug 30; Vol. 13, pp. 339. Date of Electronic Publication: 2014 Aug 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Antimalarials/*isolation & purification
Antimalarials/*pharmacology
Drug Discovery/*trends
Quinolones/*isolation & purification
Quinolones/*pharmacology
Humans
Czasopismo naukowe
    Wyświetlanie 1-10 z 10

    Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies