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    Wyświetlanie 1-9 z 9
    Tytuł:
    Case-only exome variation analysis of severe alcohol dependence using a multivariate hierarchical gene clustering approach.
    Autorzy:
    Gentry AE; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Alexander JC; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Ahangari M; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Integrative Life Sciences Ph.D. Program, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Peterson RE; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Psychiatry and Behavioral Sciences, Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, New York, United States of America.; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Miles MF; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Bettinger JC; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Davies AG; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Groteweil M; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Bacanu SA; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America.; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Kendler KS; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America.; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Riley BP; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America.; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.; Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Webb BT; VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.; GenOmics, Bioinformatics, and Translational Research Center, Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Caroline, United States of America.
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    Corporate Authors:
    VCU Alcohol Research Center working group
    Źródło:
    PloS one [PLoS One] 2023 Apr 25; Vol. 18 (4), pp. e0283985. Date of Electronic Publication: 2023 Apr 25 (Print Publication: 2023).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Alcoholism*/genetics
    Alcoholism*/diagnosis
    Humans ; Mice ; Animals ; Exome/genetics ; Alleles ; Ethanol ; Silent Mutation ; Genetic Variation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol.
    Autorzy:
    Mathies LD; Department of Pharmacology and Toxicology, Virginia Commonwealth University, PO Box 980613, Richmond, VA, 23298, USA. .
    Lindsay JH; Department of Pharmacology and Toxicology, Virginia Commonwealth University, PO Box 980613, Richmond, VA, 23298, USA.
    Handal AP; Department of Pharmacology and Toxicology, Virginia Commonwealth University, PO Box 980613, Richmond, VA, 23298, USA.
    Blackwell GG; Department of Pharmacology and Toxicology, Virginia Commonwealth University, PO Box 980613, Richmond, VA, 23298, USA.
    Davies AG; Department of Pharmacology and Toxicology, Virginia Commonwealth University, PO Box 980613, Richmond, VA, 23298, USA.
    Bettinger JC; Department of Pharmacology and Toxicology, Virginia Commonwealth University, PO Box 980613, Richmond, VA, 23298, USA.
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    Źródło:
    BMC genomics [BMC Genomics] 2020 Sep 21; Vol. 21 (1), pp. 646. Date of Electronic Publication: 2020 Sep 21.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Alcoholism/*genetics
    Caenorhabditis elegans Proteins/*metabolism
    Chromosomal Proteins, Non-Histone/*metabolism
    Histone Acetyltransferases/*metabolism
    Transcription Factors/*metabolism
    Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; Chromosomal Proteins, Non-Histone/genetics ; Ethanol/pharmacology ; Histone Acetyltransferases/genetics ; Locomotion ; Neurons/drug effects ; Neurons/metabolism ; Transcription Factors/genetics ; Transcriptome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The omega-3 fatty acid eicosapentaenoic acid is required for normal alcohol response behaviors in C. elegans.
    Autorzy:
    Raabe RC; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Mathies LD; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Davies AG; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America; VCU-Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.
    Bettinger JC; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America; VCU-Alcohol Research Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 Aug 27; Vol. 9 (8), pp. e105999. Date of Electronic Publication: 2014 Aug 27 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Dietary Supplements*
    Alcoholism/*drug therapy
    Central Nervous System Depressants/*antagonists & inhibitors
    Eicosapentaenoic Acid/*pharmacology
    Ethanol/*antagonists & inhibitors
    Alcoholism/metabolism ; Alcoholism/physiopathology ; Animals ; Behavior, Animal/drug effects ; Central Nervous System Depressants/pharmacology ; Disease Models, Animal ; Drug Tolerance ; Ethanol/pharmacology ; Humans ; Lipid Metabolism ; Motor Activity/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study.
    Autorzy:
    Zhao Z; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
    Guo AY
    van den Oord EJ
    Aliev F
    Jia P
    Edenberg HJ
    Riley BP
    Dick DM
    Bettinger JC
    Davies AG
    Grotewiel MS
    Schuckit MA
    Agrawal A
    Kramer J
    Nurnberger JI Jr
    Kendler KS
    Webb BT
    Miles MF
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    Źródło:
    BMC genomics [BMC Genomics] 2012; Vol. 13 Suppl 8, pp. S16. Date of Electronic Publication: 2012 Dec 17.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Genome-Wide Association Study*
    Alcoholism/*genetics
    Alcoholism/metabolism ; Alcoholism/pathology ; Alcohols/pharmacology ; Animals ; Caenorhabditis elegans/drug effects ; Caenorhabditis elegans/genetics ; Computational Biology ; Drosophila/drug effects ; Drosophila/genetics ; Gene Expression Regulation/drug effects ; Genetic Linkage ; Genome ; Humans ; Mice ; Polymorphism, Single Nucleotide
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-9 z 9

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