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Tytuł:
Bezafibrate attenuates immobilization-induced muscle atrophy in mice.
Autorzy:
Nakamura S; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Sato Y; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Kobayashi T; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Oya A; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Fujie A; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Matsumoto M; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Nakamura M; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
Kanaji A; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan. .
Miyamoto T; Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-Machi, Shinjuku-Ku, Tokyo, 160-8582, Japan. .; Department of Orthopedic Surgery, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 26; Vol. 14 (1), pp. 2240. Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Bezafibrate*/pharmacology
Muscular Atrophy*/drug therapy
Muscular Atrophy*/etiology
Muscular Atrophy*/metabolism
Mice ; Animals ; Muscle, Skeletal/metabolism ; Muscle Fibers, Skeletal/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Myelin Disruption, Neuroinflammation, and Oxidative Stress Induced by Sulfite in the Striatum of Rats Are Mitigated by the pan-PPAR agonist Bezafibrate.
Autorzy:
Glänzel NM; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.
Parmeggiani B; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.
Grings M; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.
Seminotti B; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.; Division of Genetic and Genomic Medicine, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Brondani M; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.
Bobermin LD; Programa de Pós-Graduação Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.
Ribeiro CAJ; Natural and Humanities Sciences Center, Universidade Federal do ABC, São Bernardo do Campo 09606-070, SP, Brazil.
Quincozes-Santos A; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.; Programa de Pós-Graduação Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.
Vockley J; Division of Genetic and Genomic Medicine, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Leipnitz G; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.; Programa de Pós-Graduação Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre 90035-003, RS, Brazil.
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Źródło:
Cells [Cells] 2023 Jun 06; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Bezafibrate*/pharmacology
Peroxisome Proliferator-Activated Receptors*/pharmacology
Rats ; Animals ; Myelin Sheath ; Neuroinflammatory Diseases ; Interleukin-6/pharmacology ; Oxidative Stress ; Sulfites/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bezafibrate in severe liver toxicity due to ibrutinib.
Autorzy:
Nasser R; Liver Unit, Rambam Health Care Campus, Haifa; Department of Gastroenterology, Rambam Health Care Campus, Haifa; Internal Medicine B, Rambam Health Care Campus. .
Sayed Ahmad N; Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. .
Veitsman E; Liver Unit, Rambam Health Care Campus, Haifa; Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. e_.
Saadi T; Liver Unit, Rambam Health Care Campus, Haifa; Department of Gastroenterology, Rambam Health Care Campus, Haifa; Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. t_.
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Źródło:
Journal of gastrointestinal and liver diseases : JGLD [J Gastrointestin Liver Dis] 2023 Apr 01; Vol. 32 (1), pp. 119-120. Date of Electronic Publication: 2023 Apr 01.
Typ publikacji:
Letter
MeSH Terms:
Bezafibrate*/therapeutic use
Hepatitis*
Humans ; Liver ; Piperidines ; Adenine
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Slow dynamics measured by phosphorescence lifetime reveals global conformational changes in human adult hemoglobin induced by allosteric effectors.
Autorzy:
Schay G; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary.
Fidy J; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary.
Herenyi L; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary.
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Źródło:
PloS one [PLoS One] 2022 Dec 01; Vol. 17 (12), pp. e0278417. Date of Electronic Publication: 2022 Dec 01 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hemoglobin A*
Radiation*
Humans ; Bezafibrate ; Entropy ; Heme
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional and Structural Insights into Human PPARα/δ/γ Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate.
Autorzy:
Honda A; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Kamata S; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Akahane M; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Machida Y; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Uchii K; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Shiiyama Y; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Habu Y; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Miyawaki S; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Kaneko C; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
Oyama T; Faculty of Life and Environmental Sciences, University of Yamanashi, Kofu 400-8510, Yamanashi, Japan.
Ishii I; Department of Health Chemistry, Showa Pharmaceutical University, Machida 194-8543, Tokyo, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Apr 25; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 25.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/metabolism
Dyslipidemias*/drug therapy
Non-alcoholic Fatty Liver Disease*
PPAR delta*/agonists
Benzoxazoles ; Bezafibrate/pharmacology ; Bezafibrate/therapeutic use ; Butyrates ; Fenofibrate/analogs & derivatives ; Humans ; Ligands ; PPAR alpha/metabolism ; PPAR gamma/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oseltamivir induces favorable response on oxidative damage in the brain of rats treated with Bezafibrate.
Autorzy:
Calderón Guzmán D; Laboratory of Neuroscience, National Institute of Pediatrics (NIP), Mexico City, Mexico.
Osnaya Brizuela N; Laboratory of Neuroscience, National Institute of Pediatrics (NIP), Mexico City, Mexico.
Ortiz Herrera M; Laboratory of Experimental Bacteriology, NIP, Mexico City, Mexico.
Juárez Olguín H; Laboratory of Pharmacology, NIP and Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Veloz Corona Q; Laboratory of Pharmacology, NIP and Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Sanchez Reyes L; Laboratory of Pharmacology, NIP and Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Valenzuela Peraza A; Laboratory of Neuroscience, National Institute of Pediatrics (NIP), Mexico City, Mexico.
Barragán Mejía G; Laboratory of Neuroscience, National Institute of Pediatrics (NIP), Mexico City, Mexico.
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Źródło:
The International journal of neuroscience [Int J Neurosci] 2022 Jun; Vol. 132 (6), pp. 574-581. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine*
Oseltamivir*/pharmacology
Adenosine Triphosphatases/metabolism ; Animals ; Bezafibrate/pharmacology ; Brain/metabolism ; Glutathione/metabolism ; Hydrogen Peroxide/pharmacology ; Hydroxyindoleacetic Acid/pharmacology ; Lipid Peroxidation ; Male ; Oxidative Stress ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Maternally inherited diabetes and deafness coexists with lipoprotein lipase gene mutation-associated severe hyperlipidemia that was resistant to fenofibrate and atorvastatin, but sensitive to bezafibrate: A case report.
Autorzy:
Zhang X; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Chen Y; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.; Department of Endocrinology and Metabolism, The Fifth People's Hospital of Chongqing, Chongqing, China.
Tong N; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Shao Q; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Zhou Y; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Mu T; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Yang X; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Zhang Y; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
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Źródło:
Journal of diabetes investigation [J Diabetes Investig] 2022 Feb; Vol. 13 (2), pp. 397-401. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji:
Case Reports
MeSH Terms:
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/genetics
Fenofibrate*/therapeutic use
Hyperlipidemias*/complications
Hyperlipidemias*/drug therapy
Hyperlipidemias*/genetics
Lipoprotein Lipase/*genetics
Atorvastatin/therapeutic use ; Bezafibrate/therapeutic use ; Deafness ; Female ; Humans ; Mitochondrial Diseases ; Mutation
SCR Disease Name:
Noninsulin-dependent diabetes mellitus with deafness
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial.
Autorzy:
Bolier R; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. .
de Vries ES; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Parés A; Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Department of Medicine, University of Barcelona, Barcelona, Spain.
Helder J; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Kemper EM; Department of pharmacy, Academic Medical Center, Amsterdam, The Netherlands.
Zwinderman K; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands.
Elferink RPO; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Beuers U; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
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Corporate Authors:
Netherlands Association for the Study of the Liver (NASL) Cholestatic Liver Diseases Study Group
Źródło:
Trials [Trials] 2017 May 23; Vol. 18 (1), pp. 230. Date of Electronic Publication: 2017 May 23.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Antipruritics/*therapeutic use
Bezafibrate/*therapeutic use
Cholangitis, Sclerosing/*complications
Liver Cirrhosis, Biliary/*complications
Pruritus/*drug therapy
Antipruritics/adverse effects ; Bezafibrate/adverse effects ; Cholangitis, Sclerosing/diagnosis ; Clinical Protocols ; Double-Blind Method ; Humans ; Liver Cirrhosis, Biliary/diagnosis ; Netherlands ; Pruritus/diagnosis ; Pruritus/etiology ; Research Design ; Spain ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Editorial: bezafibrate in the treatment of patients with primary biliary cholangitis-are we there yet?
Autorzy:
Rodrigues PM; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute, Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain.; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, 'Instituto de Salud Carlos III'), Madrid, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.
Banales JM; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute, Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain.; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, 'Instituto de Salud Carlos III'), Madrid, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.; Department of Biochemistry and Genetics, School of Sciences, University of Navarra, Pamplona, Spain.
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Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2022 Jan; Vol. 55 (2), pp. 247-248.
Typ publikacji:
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Cholangitis*/chemically induced
Cholangitis*/drug therapy
Liver Cirrhosis, Biliary*/drug therapy
Bezafibrate/therapeutic use ; Humans ; Ursodeoxycholic Acid
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Editorial: bezafibrate in the treatment of patients with primary biliary cholangitis-are we there yet? Authors' reply.
Autorzy:
Sorda JA; Department of Gastroenterology and Hepatology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
González Ballerga E; Department of Gastroenterology and Hepatology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Barreyro FJ; Biotechnology Institute of Misiones (INBIOMIS), National University of Misiones, National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Daruich J; Department of Gastroenterology and Hepatology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
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Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2022 Jan; Vol. 55 (2), pp. 249-250.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Cholangitis*/chemically induced
Cholangitis*/drug therapy
Liver Cirrhosis, Biliary*/drug therapy
Bezafibrate/therapeutic use ; Humans ; Ursodeoxycholic Acid
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Pharmacophore-guided repurposing of fibrates and retinoids as GPR40 allosteric ligands with activity on insulin release.
Autorzy:
Cione E; Department of Pharmacy, Health and Nutritional Sciences (Department of Excellence 2018-2022), University of Calabria, Rende, Italy.
Caroleo MC; Department of Pharmacy, Health and Nutritional Sciences (Department of Excellence 2018-2022), University of Calabria, Rende, Italy.
Kagechika H; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Manetti F; Department of Biotechnology, Chemistry and Pharmacy (Department of Excellence 2018-2022), University of Siena, Siena, Italy.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 377-383.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Repositioning*
Fibric Acids/*pharmacology
Insulin/*metabolism
Receptors, G-Protein-Coupled/*agonists
Retinoids/*pharmacology
Allosteric Regulation/drug effects ; Aniline Compounds/pharmacology ; Animals ; Bezafibrate/pharmacology ; Cells, Cultured ; Dose-Response Relationship, Drug ; Humans ; Ligands ; Molecular Docking Simulation ; Molecular Structure ; Propionates/pharmacology ; Rats ; Receptors, G-Protein-Coupled/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bezafibrate therapy in primary biliary cholangitis refractory to ursodeoxycholic acid: a longitudinal study of paired liver biopsies at 5 years of follow up.
Autorzy:
Sorda JA; Department of Gastroenterology and Hepatology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
González Ballerga E; Department of Gastroenterology and Hepatology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Barreyro FJ; Biotechnology Institute of Misiones (INBIOMIS), National University of Misiones, National Scientific and Technical Research Council (CONICET), Posadas, Argentina.
Avagnina A; Department of Pathology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Carballo P; Department of Pathology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Paes de Lima A; Department of Pathology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Daruich J; Department of Gastroenterology and Hepatology, University Hospital 'José de San Martín', Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
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Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2021 Nov; Vol. 54 (9), pp. 1202-1212. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Liver Cirrhosis, Biliary*/drug therapy
Ursodeoxycholic Acid*/therapeutic use
Bezafibrate/therapeutic use ; Biopsy ; Cholagogues and Choleretics/therapeutic use ; Drug Therapy, Combination ; Follow-Up Studies ; Humans ; Longitudinal Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety of fibrates in cholestatic liver diseases.
Autorzy:
Carrion AF; Division of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA.
Lindor KD; Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA.; Office of University Provost, Arizona State University, Phoenix, AZ, USA.
Levy C; Division of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA.
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Źródło:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2021 Jun; Vol. 41 (6), pp. 1335-1343. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Cholagogues and Choleretics*/adverse effects
Liver Cirrhosis, Biliary*/drug therapy
Bezafibrate/adverse effects ; Fibric Acids/adverse effects ; Humans ; Ursodeoxycholic Acid/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antifibrotic effects of bezafibrate and pioglitazone against thioacetamide-induced liver fibrosis in albino rats.
Autorzy:
Ibrahim SA; Department of Pharmacology, Minia University Faculty of Medicine, Minia, Egypt.
Mohamed MZ; Department of Pharmacology, Minia University Faculty of Medicine, Minia, Egypt.
El-Tahawy NF; Department of Histology & Cell Biology, Minia University Faculty of Medicine, Minia, Egypt.
Abdelrahman AM; Department of Pharmacology, Minia University Faculty of Medicine, Minia, Egypt.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2021 Mar; Vol. 99 (3), pp. 313-320. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Bezafibrate/*therapeutic use
Liver Cirrhosis/*chemically induced
Liver Cirrhosis/*drug therapy
Pioglitazone/*therapeutic use
Actins/biosynthesis ; Animals ; Hepatic Stellate Cells/drug effects ; Liver/pathology ; Liver Function Tests ; Male ; Malondialdehyde/blood ; Nitrites/blood ; Rats ; Thioacetamide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ursodeoxycholic acid and bezafibrate were useful for steroid-refractory, immune-related hepatitis: a case report.
Autorzy:
Onishi S; Department of Endoscopy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan. .
Tajika M; Department of Endoscopy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
Bando H; Department of Clinical Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
Matsubara Y; Department of Clinical Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
Hosoda W; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
Muro K; Department of Clinical Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
Niwa Y; Department of Endoscopy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
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Źródło:
Journal of medical case reports [J Med Case Rep] 2020 Nov 26; Vol. 14 (1), pp. 230. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Melanoma*
Skin Neoplasms*
Aged ; Bezafibrate/therapeutic use ; Humans ; Male ; Nivolumab ; Ursodeoxycholic Acid/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cessation of Bezafibrate in patients with chronic kidney disease improves renal function.
Autorzy:
Zingerman B; Community Nephrology Clinic, Clalit Health Services, Kiryat Ono, Israel. .; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. .; Department of Nephrology and Hypertension, Hasharon Hospital, Rabin Medical Center, 4941492, Petah Tikva, Israel. .
Ziv D; Division of Clinical Pharmacy, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Feder Krengel N; Community Nephrology Clinic, Clalit Health Services, Kiryat Ono, Israel.
Korzets A; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.; Department of Nephrology and Hypertension, Hasharon Hospital, Rabin Medical Center, 4941492, Petah Tikva, Israel.
Matok I; Division of Clinical Pharmacy, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 13; Vol. 10 (1), pp. 19768. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji:
Journal Article
MeSH Terms:
Bezafibrate/*pharmacokinetics
Bezafibrate/*therapeutic use
Renal Insufficiency, Chronic/*drug therapy
Renal Insufficiency, Chronic/*metabolism
Aged ; Aged, 80 and over ; Case-Control Studies ; Creatine Kinase/blood ; Creatinine/blood ; Female ; Glomerular Filtration Rate/drug effects ; Humans ; Kidney Function Tests ; Male ; Renal Insufficiency, Chronic/blood ; Retrospective Studies ; Urea/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy of Pemafibrate in Comparison to Fenofibrate and Bezafibrate on Triglyceride Levels and Liver, and Renal Functions in Patients With Hypertriglyceridemia and Type 2 Diabetes
Autorzy:
Junko Oya
Tomoko Nakagami
Yuichiro Kondo
Aki Katamine
Mika Shimizu
Yukiko Hasegawa
Tetsuya Babazono
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Temat:
bezafibrate
fenofibrate
hypertriglyceridemia
pemafibrate
Medicine
Źródło:
Tokyo Women's Medical University Journal, Vol 7, Iss 0, Pp 101-108 (2023)
Opis pliku:
electronic resource
Relacje:
https://www.jstage.jst.go.jp/article/twmuj/7/0/7_2023008/_pdf/-char/en; https://doaj.org/toc/2432-6186
Dostęp URL:
https://doaj.org/article/bac49c7903e849349bd63c2e7efbf13e  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
A validation study of the Ursodeoxycholic Acid Response Score in Japanese patients with primary biliary cholangitis.
Autorzy:
Yagi M; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Matsumoto K; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Komori A; Clinical Research Center, National Hospital Organization (NHO) Nagasaki Medical Center, Nagasaki, Japan.
Abe M; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan.
Hashimoto N; Department of Gastroenterology, Tokyo Teishin Hospital, Tokyo, Japan.
Inao M; Department of Gastroenterology and Hepatology, Faculty of Medicine, Saitama Medical University, Saitama, Japan.
Namisaki T; Third Department of Internal Medicine, Nara Medical University, Nara, Japan.
Kawata K; Hepatology Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Ninomiya M; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fujii H; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Takahashi A; Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Kang JH; Center for Gastroenterology, Teine Keijinkai Hospital, Sapporo, Japan.
Takamura M; Department of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Arakawa M; Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu City, Japan.
Joshita S; Division of Hepatology and Gastroenterology, Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Sato K; Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Itakura J; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Nomura T; Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Kagawa, Japan.
Kakisaka K; Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Kaneko A; Department of Gastroenterology, Minoh City Hospital, Osaka, Japan.
Tamura Y; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Miura R; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Aiso M; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Arizumi T; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Asaoka Y; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Kikuchi K; The Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital, Tokyo, Japan.
Takikawa Y; Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Masaki T; Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Kagawa, Japan.
Umemura T; Division of Hepatology and Gastroenterology, Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Honda A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan.
Ohira H; Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Kawada N; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Yoshiji H; Third Department of Internal Medicine, Nara Medical University, Nara, Japan.
Mochida S; Department of Gastroenterology and Hepatology, Faculty of Medicine, Saitama Medical University, Saitama, Japan.
Takikawa H; Faculty of Medical Technology, Teikyo University, Tokyo, Japan.
Tanaka A; Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
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Corporate Authors:
Japan PBC Study Group (JPBCSG)
Źródło:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2020 Aug; Vol. 40 (8), pp. 1926-1933. Date of Electronic Publication: 2020 May 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Liver Cirrhosis, Biliary*/drug therapy
Ursodeoxycholic Acid*/therapeutic use
Aged ; Alkaline Phosphatase ; Bezafibrate/therapeutic use ; Cholagogues and Choleretics/therapeutic use ; Female ; Humans ; Japan ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bezafibrate for the treatment of dyslipidemia in patients with coronary artery disease: 20-year mortality follow-up of the BIP randomized control trial.
Autorzy:
Arbel Y; Department of Cardiology, Tel Aviv Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. .
Klempfner R; Leviev Heart Center, Sheba Medical Center, Tel Aviv, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. .; The Israeli Association for Cardiovascular Trials, Tel Hashomer, Israel. .
Erez A; Leviev Heart Center, Sheba Medical Center, Tel Aviv, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. .
Goldenberg I; Leviev Heart Center, Sheba Medical Center, Tel Aviv, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. .; The Israeli Association for Cardiovascular Trials, Tel Hashomer, Israel. .; Heart Research Follow-up Program, University of Rochester, Rochester, NY, USA. .
Benzekry S; Leviev Heart Center, Sheba Medical Center, Tel Aviv, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. .
Shlomo N; The Israeli Association for Cardiovascular Trials, Tel Hashomer, Israel. .
Fisman EZ; Cardiovascular Diabetology Research Foundation, Holon, Israel. .
Tenenbaum A; Cardiovascular Diabetology Research Foundation, Holon, Israel. .
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Corporate Authors:
BIP Study Group
Źródło:
Cardiovascular diabetology [Cardiovasc Diabetol] 2016 Jan 22; Vol. 15, pp. 11. Date of Electronic Publication: 2016 Jan 22.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Bezafibrate/*therapeutic use
Coronary Artery Disease/*mortality
Hypertriglyceridemia/*drug therapy
Hypertriglyceridemia/*mortality
Hypolipidemic Agents/*therapeutic use
Triglycerides/*blood
Aged ; Bezafibrate/adverse effects ; Biomarkers/blood ; Chi-Square Distribution ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/etiology ; Female ; Follow-Up Studies ; Humans ; Hypertriglyceridemia/blood ; Hypertriglyceridemia/complications ; Hypertriglyceridemia/diagnosis ; Hypolipidemic Agents/adverse effects ; Intention to Treat Analysis ; Israel ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Multivariate Analysis ; Proportional Hazards Models ; Registries ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 946

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