A mass spectrometry-based assay using metabolic labeling to rapidly monitor chromatin accessibility of modified histone proteins.
Autorzy:
Sidoli S; Epigenetics Institute, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. Lopes M; Epigenetics Institute, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Laboratório Especial de Ciclo Celular, Center of Toxins, Immune Response and Cell Signaling - CeTICS, Instituto Butantan, São Paulo, 05503-900, Brazil. Lund PJ; Epigenetics Institute, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Goldman N; Epigenetics Institute, Institute for Immunology, Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Immunology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Fasolino M; Epigenetics Institute, Institute for Immunology, Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Coradin M; Epigenetics Institute, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Kulej K; Epigenetics Institute, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. BhanuNV; Epigenetics Institute, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Vahedi G; Epigenetics Institute, Institute for Immunology, Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Garcia BA; Epigenetics Institute, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Sep 20; Vol. 9 (1), pp. 13613. Date of Electronic Publication: 2019 Sep 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells.
Autorzy:
Gonzales-Cope M; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. . Sidoli S; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. . BhanuNV; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. . Won KJ; The Institute for Diabetes, Obesity, and Metabolism, Philadelphia, PA, 19104, USA. .; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. . Garcia BA; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. .
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Źródło:
BMC genomics [BMC Genomics] 2016 Feb 04; Vol. 17, pp. 95. Date of Electronic Publication: 2016 Feb 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications.
Autorzy:
Molden RC; Department of Chemistry, Princeton University, Princeton, NJ 08544 USA. BhanuNV; Department of Biochemistry and Biophysics, Epigenetics Program, Perelman School of Medicine, University of Pennsylvania, Room 9-124, 3400 Civic Center Blvd., Bldg. 421, Philadelphia, PA 19104 USA. LeRoy G; Department of Chemistry, Princeton University, Princeton, NJ 08544 USA. Arnaudo AM; Department of Chemistry, Princeton University, Princeton, NJ 08544 USA ; Department of Biochemistry and Biophysics, Epigenetics Program, Perelman School of Medicine, University of Pennsylvania, Room 9-124, 3400 Civic Center Blvd., Bldg. 421, Philadelphia, PA 19104 USA. Garcia BA; Department of Biochemistry and Biophysics, Epigenetics Program, Perelman School of Medicine, University of Pennsylvania, Room 9-124, 3400 Civic Center Blvd., Bldg. 421, Philadelphia, PA 19104 USA.
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Źródło:
Epigenetics & chromatin [Epigenetics Chromatin] 2015 Apr 22; Vol. 8, pp. 15. Date of Electronic Publication: 2015 Apr 22 (Print Publication: 2015).
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