Temat: "Bile Ducts" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Targeting polycomb repressor complex 2-mediated bivalent promoter epigenetic silencing of secreted frizzled-related protein 1 inhibits cholangiocarcinoma progression.
Autorzy:: Wu G; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Wang Q; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Wang D; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Xiong F; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Liu W; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Chen J; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Wang B; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Huang W; Department of Emergency, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Wang X; Departement of Pediatric Surgery, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Chen Y; Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2023 Dec; Vol. 13 (12), pp. e1502.
Typ publikacji:: Journal Article
MeSH Terms:: Cholangiocarcinoma*/drug therapy
Cholangiocarcinoma*/genetics
Cholangiocarcinoma*/metabolism
Bile Duct Neoplasms*/drug therapy
Bile Duct Neoplasms*/genetics
Bile Duct Neoplasms*/metabolism
Animals ; Mice ; Humans ; Histones/metabolism ; Secreted Frizzled-Related Proteins ; Enhancer of Zeste Homolog 2 Protein/genetics ; Epigenesis, Genetic/genetics ; Bile Ducts, Intrahepatic/metabolism ; Bile Ducts, Intrahepatic/pathology ; RNA, Messenger ; DNA

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Skocz do pozycji: 2.

Tytuł:: Population pharmacokinetic and exposure-response analyses of pemigatinib in patients with advanced solid tumors including cholangiocarcinoma.
Autorzy:: Gong X; Incyte Research Institute, Wilmington, Delaware, USA.
Akil A; Certara Strategic Consulting, Princeton, New Jersey, USA.
Ndi A; Certara Strategic Consulting, Princeton, New Jersey, USA.
Ji T; Allorion Therapeutics, Natick, Massachusetts, USA.
Liu X; Incyte Research Institute, Wilmington, Delaware, USA.
Lovern M; Certara Strategic Consulting, Princeton, New Jersey, USA.
Chen X; Incyte Research Institute, Wilmington, Delaware, USA.; Pokaż więcej
Źródło:: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Nov; Vol. 12 (11), pp. 1784-1794. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:: Journal Article
MeSH Terms:: Cholangiocarcinoma*/drug therapy
Bile Duct Neoplasms*/drug therapy
Humans ; Bile Ducts, Intrahepatic ; Phosphates/therapeutic use

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Skocz do pozycji: 3.

Tytuł:: Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro.
Autorzy:: Roos FJM; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Wu H; Department of Molecular Biology, Radboud University, Nijmegen, The Netherlands.
Willemse J; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Lieshout R; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Albarinos LAM; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Kan YY; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Poley JW; Erasmus MC, Department of Gastroenterology and Hepatology, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Bruno MJ; Erasmus MC, Department of Gastroenterology and Hepatology, University Medical Center Rotterdam, Rotterdam, The Netherlands.
de Jonge J; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Bártfai R; Department of Molecular Biology, Radboud University, Nijmegen, The Netherlands.
Marks H; Department of Molecular Biology, Radboud University, Nijmegen, The Netherlands.
IJzermans JNM; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Verstegen MMA; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
van der Laan LJW; Erasmus MC, Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2021 Dec; Vol. 11 (12), pp. e566.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phenotype*
Bile Acids and Salts/*genetics
Bile Ducts/*chemistry
Organoids/*chemistry
Adolescent ; Adult ; Aged ; Bile Ducts/physiopathology ; Female ; Humans ; Male ; Middle Aged ; Organoids/metabolism

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Skocz do pozycji: 4.

Tytuł:: Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of CAFs in intrahepatic cholangiocarcinoma.
Autorzy:: Li JH; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Wu X; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Ni X; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Li YX; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Xu L; Department of Physiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Hao XY; Lau Luen Hung Private Medical Center, Unit 3 (Surgery), The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Zhao W; Key Laboratory of Stem Cells and Tissue Engineering, Sun Yat-sen University, Ministry of Education, Guangzhou, Guangdong, China.
Zhu XX; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Yin XY; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2023 Mar; Vol. 13 (3), pp. e1213.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cancer-Associated Fibroblasts*
Cholangiocarcinoma*/drug therapy
Bile Duct Neoplasms*/drug therapy
Animals ; Humans ; Angiotensin Receptor Antagonists/pharmacology ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors ; Disease Models, Animal ; Bile Ducts, Intrahepatic ; Receptor, Angiotensin, Type 1/genetics

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Skocz do pozycji: 5.

Tytuł:: Condensed tannins from Ulmus pumila L. leaves induce G2/M phase arrest and apoptosis via caspase-cascade activation in TFK-1 cholangiocarcinoma cells.
Autorzy:: Ren Y; College of Life Science, Yangtze University, Jingzhou, China.; College of Life Science and Engineering, Henan University of Urban Construction, Pingdingshan, China.
Qin Z; College of Life Science, Yangtze University, Jingzhou, China.
Wang Z; Forestry and Fruit Tree Research Institute, Wuhan Academy of Agricultural Sciences, Wuhan, China.
Wei S; College of Life Science, Yangtze University, Jingzhou, China.
Chen H; College of Life Science, Yangtze University, Jingzhou, China.
Zhu T; College of Life Science and Engineering, Henan University of Urban Construction, Pingdingshan, China.
Liu L; College of Life Science, Yangtze University, Jingzhou, China.
Zhao Y; College of Life Science, Yangtze University, Jingzhou, China.
Ding B; College of Life Science, Yangtze University, Jingzhou, China.
Song W; College of Life Science and Engineering, Henan University of Urban Construction, Pingdingshan, China.; Pokaż więcej
Źródło:: Journal of food biochemistry [J Food Biochem] 2022 Oct; Vol. 46 (10), pp. e14374. Date of Electronic Publication: 2022 Aug 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bile Duct Neoplasms*/drug therapy
Bile Duct Neoplasms*/metabolism
Bile Duct Neoplasms*/pathology
Catechin*/pharmacology
Cholangiocarcinoma*/drug therapy
Cholangiocarcinoma*/metabolism
Cholangiocarcinoma*/pathology
Proanthocyanidins*/pharmacology
Ulmus*/metabolism
Apoptosis ; Bile Ducts, Intrahepatic/metabolism ; Bile Ducts, Intrahepatic/pathology ; Caspase 3/metabolism ; Caspase 8/genetics ; Caspase 8/metabolism ; Caspase 8/pharmacology ; Caspases/metabolism ; Caspases/pharmacology ; Caspases/therapeutic use ; Cell Cycle Checkpoints ; Cell Division ; Cyclin E/metabolism ; Cyclin E/pharmacology ; Cytochromes c/metabolism ; Cytochromes c/pharmacology ; Cytochromes c/therapeutic use ; Humans ; Spectroscopy, Fourier Transform Infrared ; Tumor Suppressor Protein p53

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Skocz do pozycji: 6.

Tytuł:: Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis.
Autorzy:: Saffioti F; Sheila Sherlock Liver Centre and UCL Institute for Liver and Digestive Health, University College London & Royal Free London NHS Foundation Trust, London, UK.; Department of Clinical and Experimental Medicine, Division of Clinical and Molecular Hepatology, University of Messina, Messina, Italy.
Roccarina D; Sheila Sherlock Liver Centre and UCL Institute for Liver and Digestive Health, University College London & Royal Free London NHS Foundation Trust, London, UK.
Vesterhus M; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway.
Hov JR; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Section of Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Rosenberg W; Sheila Sherlock Liver Centre and UCL Institute for Liver and Digestive Health, University College London & Royal Free London NHS Foundation Trust, London, UK.
Pinzani M; Sheila Sherlock Liver Centre and UCL Institute for Liver and Digestive Health, University College London & Royal Free London NHS Foundation Trust, London, UK.
Pereira SP; Sheila Sherlock Liver Centre and UCL Institute for Liver and Digestive Health, University College London & Royal Free London NHS Foundation Trust, London, UK.
Boberg KM; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Section of Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Thorburn D; Sheila Sherlock Liver Centre and UCL Institute for Liver and Digestive Health, University College London & Royal Free London NHS Foundation Trust, London, UK.; Pokaż więcej
Źródło:: European journal of clinical investigation [Eur J Clin Invest] 2019 May; Vol. 49 (5), pp. e13088. Date of Electronic Publication: 2019 Mar 18.
Typ publikacji:: Evaluation Study; Journal Article
MeSH Terms:: Bile Ducts, Intrahepatic*
Bile Duct Neoplasms/*complications
Cholangiocarcinoma/*complications
Klatskin Tumor/*complications
Liver Cirrhosis/*etiology
Aged ; Biomarkers/metabolism ; Cholangitis, Sclerosing ; Female ; Humans ; Inflammatory Bowel Diseases/complications ; Male ; Middle Aged ; Neoplasm Metastasis ; Retrospective Studies ; Risk Assessment

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Skocz do pozycji: 7.

Tytuł:: YTHDF2 promotes intrahepatic cholangiocarcinoma progression and desensitises cisplatin treatment by increasing CDKN1B mRNA degradation.
Autorzy:: Huang CS; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhu YQ; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xu QC; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chen S; Key Laboratory of Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
Huang Y; Department of Biotherapy, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhao G; Department of Animal Experiment Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Ni X; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Liu B; Key Laboratory of Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
Zhao W; Key Laboratory of Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
Yin XY; Department of Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2022 Jun; Vol. 12 (6), pp. e848.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bile Duct Neoplasms*/drug therapy
Bile Duct Neoplasms*/genetics
Bile Duct Neoplasms*/metabolism
Cholangiocarcinoma*/drug therapy
Cholangiocarcinoma*/genetics
Cholangiocarcinoma*/metabolism
Bile Ducts, Intrahepatic/metabolism ; Bile Ducts, Intrahepatic/pathology ; Carcinogenesis ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cisplatin/metabolism ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Cyclin-Dependent Kinase Inhibitor p27/therapeutic use ; Humans ; RNA Stability/genetics ; RNA, Small Interfering/metabolism ; RNA, Small Interfering/therapeutic use ; RNA-Binding Proteins/genetics

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Skocz do pozycji: 8.

Tytuł:: Finite element simulation and optimization of mechanical performance of the magnesium-alloy biliary stent.
Autorzy:: Zhang Y; School of Mechanical and Electronic Engineering, Nanjing Forestry University, Nanjing, Jiangsu Province, China.
Ni X; School of Mechanical and Electronic Engineering, Nanjing Forestry University, Nanjing, Jiangsu Province, China.
Pan C; Jiangsu Key Laboratory for Design and Manufacture of Micro/Nano Biomedical Instruments Micro-Tech (Nanjing) Co., Ltd, Nanjing, Jiangsu Province, China.; Pokaż więcej
Źródło:: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2022 May; Vol. 38 (5), pp. e3592. Date of Electronic Publication: 2022 Mar 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alloys*
Magnesium*
Bile Ducts/surgery ; Finite Element Analysis ; Stents

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Skocz do pozycji: 9.

Tytuł:: The degradable performance of bile-duct stent based on a continuum damage model: A finite element analysis.
Autorzy:: Ni X; School of Mechanical and Electronic Engineering, Nanjing Forestry University, Nanjing, China.
Zhang Y; School of Mechanical and Electronic Engineering, Nanjing Forestry University, Nanjing, China.
Pan C; Jiangsu Key Laboratory for Design and Manufacture of Micro/Nano Biomedical Instruments, Micro-Tech (Nanjing) Co., Ltd., Nanjing, China.; Pokaż więcej
Źródło:: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2020 Aug; Vol. 36 (8), pp. e3370. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alloys*
Bile*
Stents*
Bile Ducts ; Finite Element Analysis

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Skocz do pozycji: 10.

Tytuł:: The many ways to mend your liver: A critical appraisal.
Autorzy:: Alison MR; Centre for Tumour Biology, Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, London, UK.; Pokaż więcej
Źródło:: International journal of experimental pathology [Int J Exp Pathol] 2018 Jun; Vol. 99 (3), pp. 106-112. Date of Electronic Publication: 2018 Jun 07.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cell Differentiation*
Cell Lineage*
Cell Proliferation*
Liver Regeneration*
Hepatocytes/*pathology
Liver/*pathology
Liver Diseases/*pathology
Stem Cells/*pathology
Animals ; Bile Ducts/metabolism ; Bile Ducts/pathology ; Hepatocytes/metabolism ; Humans ; Liver/metabolism ; Liver/physiopathology ; Liver Diseases/metabolism ; Liver Diseases/physiopathology ; Phenotype ; Signal Transduction ; Stem Cells/metabolism

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Skocz do pozycji: 11.

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Skocz do pozycji: 12.

Tytuł:: The anti-hepatic fibrosis effects of dihydrotanshinone I are mediated by disrupting the yes-associated protein and transcriptional enhancer factor D2 complex and stimulating autophagy.
Autorzy:: Ge M; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liu H; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhang Y; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li N; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhao S; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhao W; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhen Y; Hebei Key Laboratory for Chronic Diseases, School of Basic Medical Sciences, North China University of Science and Technology, Tangshan, China.
Yu J; Department of Anatomy and Physiology, Kansas State University College of Veterinary Medicine, Manhattan, KS, 66506, USA.
He H; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shao RG; Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2017 May; Vol. 174 (10), pp. 1147-1160. Date of Electronic Publication: 2017 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis Regulatory Proteins/*antagonists & inhibitors
Autophagy/*drug effects
Hepatic Stellate Cells/*drug effects
Liver Cirrhosis/*drug therapy
Phenanthrenes/*pharmacology
Transcription Factors/*antagonists & inhibitors
Animals ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Bile Ducts/pathology ; Bile Ducts/surgery ; Cell Line ; Dose-Response Relationship, Drug ; Furans ; Humans ; Ligation ; Liver Cirrhosis/genetics ; Liver Cirrhosis/pathology ; Male ; Molecular Structure ; Phenanthrenes/administration & dosage ; Phenanthrenes/chemistry ; Quinones ; Rats ; Rats, Sprague-Dawley ; Structure-Activity Relationship ; Transcription Factors/genetics ; Transcription Factors/metabolism ; YAP-Signaling Proteins