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Wyszukujesz frazę ""Binding, Competitive"" wg kryterium: Temat


Tytuł :
Dynamics of competitive binding and separation of monoclonal antibody monomer-dimer mixtures in ceramic hydroxyapatite columns.
Autorzy :
Wang Y; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA.
Carta G; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2020 Jan 04; Vol. 1609, pp. 460504. Date of Electronic Publication: 2019 Aug 30.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3778 (Electronic) Linking ISSN: 00219673 NLM ISO Abbreviation: J Chromatogr A Subsets: MEDLINE
MeSH Terms :
Binding, Competitive*
Dimerization*
Antibodies, Monoclonal/*isolation & purification
Ceramics/*chemistry
Durapatite/*chemistry
Adsorption ; Diffusion ; Kinetics ; Models, Theoretical
Czasopismo naukowe
Tytuł :
Development of a Competition-Binding Assay to Determine Binding Affinity of Molecules to Neuromelanin via Fluorescence Spectroscopy.
Autorzy :
Fink J; School of Science and Technology, Georgia Gwinnett College, 1000 University Center Lane, Lawrenceville, GA 30043, USA. .
Pathak H; School of Science and Technology, Georgia Gwinnett College, 1000 University Center Lane, Lawrenceville, GA 30043, USA. .
Smith J; School of Science and Technology, Georgia Gwinnett College, 1000 University Center Lane, Lawrenceville, GA 30043, USA. .
Achat-Mendes C; School of Science and Technology, Georgia Gwinnett College, 1000 University Center Lane, Lawrenceville, GA 30043, USA. .
Haining RL; School of Science and Technology, Georgia Gwinnett College, 1000 University Center Lane, Lawrenceville, GA 30043, USA. .
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Źródło :
Biomolecules [Biomolecules] 2019 May 08; Vol. 9 (5). Date of Electronic Publication: 2019 May 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE
MeSH Terms :
Binding, Competitive*
Biological Assay*
Melanins/*metabolism
Animals ; Catecholamines/metabolism ; Cells, Cultured ; Humans ; Nicotine/metabolism ; Nicotine/pharmacology ; Oxidation-Reduction ; Oxidopamine/metabolism ; Polymerization ; Rats ; Signal Transduction ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
Natural receptor-based competitive immunoelectrochemical assay for ultra-sensitive detection of Siglec 15.
Autorzy :
Zhu Z; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, PR China.
Zhu J; Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, PR China.
Zhao J; School of Life Sciences, Shanghai University, Shanghai, 200444, PR China.
Zhu K; Department of Burns and Plastic Surgery, General Hospital of Liaoning Provincial Armed Police Force of PLA, Shenyang, 110034, PR China.
Xu Q; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, PR China. Electronic address: .
Chen H; School of Life Sciences, Shanghai University, Shanghai, 200444, PR China. Electronic address: .
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Źródło :
Biosensors & bioelectronics [Biosens Bioelectron] 2020 Mar 01; Vol. 151, pp. 111950. Date of Electronic Publication: 2019 Dec 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4235 (Electronic) Linking ISSN: 09565663 NLM ISO Abbreviation: Biosens Bioelectron Subsets: MEDLINE
MeSH Terms :
Adaptor Proteins, Signal Transducing/*chemistry
Biomarkers, Tumor/*blood
Immunoglobulins/*blood
Magnetite Nanoparticles/*chemistry
Membrane Proteins/*blood
Membrane Proteins/*chemistry
Neoplasms/*diagnosis
Adaptor Proteins, Signal Transducing/immunology ; Binding, Competitive ; Biomarkers, Tumor/immunology ; Biosensing Techniques/methods ; Electrochemical Techniques/methods ; Electrodes ; Humans ; Immobilized Proteins/chemistry ; Immunoglobulins/chemistry ; Immunoglobulins/immunology ; Membrane Proteins/immunology ; Sensitivity and Specificity ; Signal Transduction ; Surface Properties
Czasopismo naukowe
Tytuł :
Three Chemosensory Proteins Involved in Chemoreception of Oedaleus asiaticus (Orthopera: Acridoidea).
Autorzy :
Zhou YT; Research Center for Grassland Entomology, Inner Mongolia Agricultural University, Hohhot, 010020, China.; College of Agriculture and Animal Husbandry, Qinghai University, Xining, 810016, China.
Li L; Research Center for Grassland Entomology, Inner Mongolia Agricultural University, Hohhot, 010020, China.
Zhou XR; Research Center for Grassland Entomology, Inner Mongolia Agricultural University, Hohhot, 010020, China.
Tan Y; Research Center for Grassland Entomology, Inner Mongolia Agricultural University, Hohhot, 010020, China.
Pang BP; Research Center for Grassland Entomology, Inner Mongolia Agricultural University, Hohhot, 010020, China. .
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Źródło :
Journal of chemical ecology [J Chem Ecol] 2020 Feb; Vol. 46 (2), pp. 138-149. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Springer Country of Publication: United States NLM ID: 7505563 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-1561 (Electronic) Linking ISSN: 00980331 NLM ISO Abbreviation: J. Chem. Ecol. Subsets: MEDLINE
MeSH Terms :
Grasshoppers/*metabolism
Insect Proteins/*metabolism
Receptors, Odorant/*metabolism
Animals ; Binding, Competitive ; Female ; Insect Proteins/antagonists & inhibitors ; Insect Proteins/genetics ; Male ; Poaceae/chemistry ; Poaceae/metabolism ; Protein Binding ; RNA Interference ; RNA, Double-Stranded/metabolism ; Receptors, Odorant/antagonists & inhibitors ; Receptors, Odorant/chemistry ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Volatile Organic Compounds/chemistry ; Volatile Organic Compounds/metabolism
Czasopismo naukowe
Tytuł :
Competitive adsorption of heavy metals in aqueous solution onto biochar derived from anaerobically digested sludge.
Autorzy :
Ni BJ; State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, PR China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, PR China.
Huang QS; State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, PR China.
Wang C; State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, PR China.
Ni TY; State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, PR China.
Sun J; State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, PR China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, PR China. Electronic address: .
Wei W; State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, PR China. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2019 Mar; Vol. 219, pp. 351-357. Date of Electronic Publication: 2018 Dec 07.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 0320657 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1298 (Electronic) Linking ISSN: 00456535 NLM ISO Abbreviation: Chemosphere Subsets: MEDLINE
MeSH Terms :
Binding, Competitive*
Charcoal/*chemistry
Metals, Heavy/*isolation & purification
Sewage/*chemistry
Adsorption ; Cadmium/chemistry ; Cadmium/isolation & purification ; Lead/chemistry ; Lead/isolation & purification ; Metals, Heavy/analysis ; Metals, Heavy/chemistry ; Sewage/microbiology ; Waste Water/chemistry ; Water Pollutants, Chemical/chemistry ; Water Pollutants, Chemical/isolation & purification ; Water Purification/methods
Czasopismo naukowe
Tytuł :
Competitive binding of monoclonal antibody monomer-dimer mixtures on ceramic hydroxyapatite.
Autorzy :
Wang Y; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA.
Carta G; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, USA. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2019 Feb 22; Vol. 1587, pp. 136-145. Date of Electronic Publication: 2018 Dec 13.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3778 (Electronic) Linking ISSN: 00219673 NLM ISO Abbreviation: J Chromatogr A Subsets: MEDLINE
MeSH Terms :
Binding, Competitive*
Protein Multimerization*
Antibodies, Monoclonal/*metabolism
Ceramics/*chemistry
Durapatite/*chemistry
Adsorption ; Chromatography, Gel ; Diffusion ; Kinetics ; Polymers/chemistry ; Porosity ; Temperature
Czasopismo naukowe
Tytuł :
Latent viruses can cause disease by disrupting the competition for the limiting factor p300/CBP.
Autorzy :
Polansky H; The Center for the Biology of Chronic Disease (CBCD), 616 Corporate Way, Suite 2-3665, Valley Cottage, New York City, NY 10989 USA.
Schwab H; The Center for the Biology of Chronic Disease (CBCD), 616 Corporate Way, Suite 2-3665, Valley Cottage, New York City, NY 10989 USA.
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Źródło :
Cellular & molecular biology letters [Cell Mol Biol Lett] 2018 Nov 26; Vol. 23, pp. 56. Date of Electronic Publication: 2018 Nov 26 (Print Publication: 2018).
Typ publikacji :
Journal Article; Review
Journal Info :
Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: eCollection Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell. Mol. Biol. Lett. Subsets: MEDLINE
MeSH Terms :
Binding, Competitive*
Virus Diseases/*metabolism
p300-CBP Transcription Factors/*metabolism
Humans ; Protein Binding ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Selenocysteine as a Substrate, an Inhibitor and a Mechanistic Probe for Bacterial and Fungal Iron-Dependent Sulfoxide Synthases.
Autorzy :
Goncharenko KV; Department of Chemistry, University of Basel, Mattenstrasse 24a, 4002, Basel, Switzerland.
Flückiger S; Department of Chemistry, University of Basel, Mattenstrasse 24a, 4002, Basel, Switzerland.
Liao C; Department of Chemistry, University of Basel, Mattenstrasse 24a, 4002, Basel, Switzerland.
Lim D; Department of Chemistry, University of Basel, Mattenstrasse 24a, 4002, Basel, Switzerland.
Stampfli AR; Department of Chemistry, University of Basel, Mattenstrasse 24a, 4002, Basel, Switzerland.
Seebeck FP; Department of Chemistry, University of Basel, Mattenstrasse 24a, 4002, Basel, Switzerland.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Jan 27; Vol. 26 (6), pp. 1328-1334. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
MeSH Terms :
Acidobacteria/*enzymology
Bacterial Proteins/*antagonists & inhibitors
Fungal Proteins/*antagonists & inhibitors
Selenocysteine/*chemistry
Bacterial Proteins/metabolism ; Binding Sites ; Binding, Competitive ; Biocatalysis ; Catalytic Domain ; Cysteine Dioxygenase/antagonists & inhibitors ; Cysteine Dioxygenase/metabolism ; Ergothioneine/chemistry ; Ergothioneine/metabolism ; Fungal Proteins/metabolism ; Kinetics ; Molecular Dynamics Simulation ; Mycobacteriaceae/enzymology ; Selenocysteine/metabolism
SCR Organism :
Chloracidobacterium thermophilum; Mycolicibacterium thermoresistibile
Czasopismo naukowe
Tytuł :
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations.
Autorzy :
Zhu K; School of Biological Science and Technology, University of Jinan.
Du D; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences.
Yang R; School of Biological Science and Technology, University of Jinan.
Tao H; School of Biological Science and Technology, University of Jinan.
Zhang H; School of Biological Science and Technology, University of Jinan.
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Źródło :
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2020 Jan 01; Vol. 68 (1), pp. 58-63. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Pharmaceutical Society of Japan Country of Publication: Japan NLM ID: 0377775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-5223 (Electronic) Linking ISSN: 00092363 NLM ISO Abbreviation: Chem. Pharm. Bull. Subsets: MEDLINE
MeSH Terms :
Molecular Docking Simulation*
Polycomb Repressive Complex 2/*metabolism
Small Molecule Libraries/*chemistry
Binding Sites ; Binding, Competitive ; Catalytic Domain ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Design ; Humans ; Polycomb Repressive Complex 2/antagonists & inhibitors ; Polycomb Repressive Complex 2/genetics ; Protein Interaction Domains and Motifs/drug effects ; Protein Subunits/antagonists & inhibitors ; Protein Subunits/genetics ; Protein Subunits/metabolism ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Small Molecule Libraries/metabolism ; Small Molecule Libraries/pharmacology
Czasopismo naukowe
Tytuł :
Interaction between an (-)-epigallocatechin-3-gallate-copper complex and bovine serum albumin: Fluorescence, circular dichroism, HPLC, and docking studies.
Autorzy :
Zhang L; Institute of Chemical Industry of Forest Products, CAF, Nanjing 210042, China; Key Lab. of Biomass Energy and Material, Nanjing, Jiangsu Province 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210042, China. Electronic address: .
Liu Y; Institute of Chemical Industry of Forest Products, CAF, Nanjing 210042, China; Key Lab. of Biomass Energy and Material, Nanjing, Jiangsu Province 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210042, China.
Wang Y; Institute of Chemical Industry of Forest Products, CAF, Nanjing 210042, China; Key Lab. of Biomass Energy and Material, Nanjing, Jiangsu Province 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210042, China.
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Źródło :
Food chemistry [Food Chem] 2019 Dec 15; Vol. 301, pp. 125294. Date of Electronic Publication: 2019 Jul 29.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
MeSH Terms :
Catechin/*analogs & derivatives
Copper/*chemistry
Serum Albumin, Bovine/*chemistry
Binding, Competitive ; Catechin/chemistry ; Catechin/metabolism ; Chromatography, High Pressure Liquid ; Circular Dichroism ; Coordination Complexes/chemistry ; Coordination Complexes/metabolism ; Copper/metabolism ; Ligands ; Molecular Docking Simulation ; Protein Structure, Secondary ; Serum Albumin, Bovine/metabolism ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
Fragment-based design of small molecule PCSK9 inhibitors using simulated annealing of chemical potential simulations.
Autorzy :
Guarnieri F; Center for Drug Discovery, Northeastern University, Boston, MA, United States of America.; PAKA Pulmonary Pharmaceuticals, Acton, MA, United States of America.
Kulp JL Jr; Conifer Point Pharmaceuticals, Doylestown, PA, United States of America.
Kulp JL 3rd; Conifer Point Pharmaceuticals, Doylestown, PA, United States of America.; Department of Chemistry, Baruch S. Blumberg Institute, Doylestown, PA, United States of America.
Cloudsdale IS; Conifer Point Pharmaceuticals, Doylestown, PA, United States of America.
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Źródło :
PloS one [PLoS One] 2019 Dec 05; Vol. 14 (12), pp. e0225780. Date of Electronic Publication: 2019 Dec 05 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
Computer Simulation*
Drug Design*
Enzyme Inhibitors/*pharmacology
Proprotein Convertase 9/*antagonists & inhibitors
Small Molecule Libraries/*pharmacology
Acetylene/chemistry ; Benzimidazoles/chemistry ; Binding, Competitive ; Enzyme Assays ; Enzyme Inhibitors/chemistry ; Hep G2 Cells ; Humans ; Models, Molecular ; Proprotein Convertase 9/metabolism ; Protein Binding/drug effects ; Protein Interaction Maps ; Receptors, LDL/metabolism ; Rotation
Czasopismo naukowe
Tytuł :
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems.
Autorzy :
Grillo A; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
Chemi G; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
Brogi S; Department of Pharmacy, University of Pisa, via Bonanno 6, 56126, Pisa, Italy.
Brindisi M; Department of Pharmacy, University of Napoli Federico II, DoE Department of Excellence 2018-2022, Via D. Montesano 49, 80131, Napoli, Italy.
Relitti N; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
Fezza F; Department of Experimental Medicine, University of Rome Tor Vergata, via Montpellier 1, 00133, Rome, Italy.
Fazio D; Faculty of Biosciences and Technology for Food Agriculture and Environment, University of Teramo, via R. Balzarini 1, 64100, Teramo, Italy; Department of Medicine, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 21, 00128, Rome, Italy.
Castelletti L; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
Perdona E; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
Wong A; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
Lamponi S; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
Pecorelli A; NC State University, Plants for Human Health Institute, 600 Laureate Way, Kannapolis, NC, 28081, USA.
Benedusi M; Department of Biomedical and Specialist Surgical Sciences, University of Ferrara, Via Borsari 46, 44121, Ferrara, Italy.
Fantacci M; Department of Life Sciences, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
Valoti M; Department of Life Sciences, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
Valacchi G; NC State University, Plants for Human Health Institute, 600 Laureate Way, Kannapolis, NC, 28081, USA; Department of Biomedical and Specialist Surgical Sciences, University of Ferrara, Via Borsari 46, 44121, Ferrara, Italy; Department of Food and Nutrition, Kyung Hee University, Seoul, South Korea.
Micheli F; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
Novellino E; Department of Pharmacy, University of Napoli Federico II, DoE Department of Excellence 2018-2022, Via D. Montesano 49, 80131, Napoli, Italy.
Campiani G; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy. Electronic address: .
Butini S; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy. Electronic address: .
Maccarrone M; Department of Medicine, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 21, 00128, Rome, Italy; European Center for Brain Research, Santa Lucia Foundation IRCCS, Via del Fosso di Fiorano snc, 00176, Rome, Italy.
Gemma S; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2019 Dec 01; Vol. 183, pp. 111674. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
MeSH Terms :
Amidohydrolases/*antagonists & inhibitors
Dopamine/*metabolism
Endocannabinoids/*metabolism
Amidohydrolases/metabolism ; Binding, Competitive ; Cell Line ; Cell Survival/drug effects ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Humans ; Ligands ; Piperazines/chemistry ; Piperazines/pharmacology ; Pyrroles/chemistry ; Pyrroles/pharmacology
Czasopismo naukowe
Tytuł :
Modelling the variable incorporation of aromatic amino acids in the tyrocidines and analogous cyclodecapeptides.
Autorzy :
Vosloo JA; Department of Biochemistry, Faculty of Science, Stellenbosch University, Stellenbosch, South Africa.
Snoep JL; Department of Biochemistry, Faculty of Science, Stellenbosch University, Stellenbosch, South Africa.; Molecular Cell Physiology, Vrije Universiteit Amsterdam, HV Amsterdam, The Netherlands.; MIB, University of Manchester, Manchester, UK.
Rautenbach M; Department of Biochemistry, Faculty of Science, Stellenbosch University, Stellenbosch, South Africa.
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Źródło :
Journal of applied microbiology [J Appl Microbiol] 2019 Dec; Vol. 127 (6), pp. 1665-1676. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Published for the Society for Applied Bacteriology by Blackwell Science Country of Publication: England NLM ID: 9706280 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2672 (Electronic) Linking ISSN: 13645072 NLM ISO Abbreviation: J. Appl. Microbiol. Subsets: MEDLINE
MeSH Terms :
Amino Acids, Aromatic/*metabolism
Anti-Bacterial Agents/*biosynthesis
Brevibacillus/*metabolism
Peptides, Cyclic/*biosynthesis
Tyrocidine/*biosynthesis
Binding, Competitive ; Chromatography, Liquid ; Mass Spectrometry ; Models, Theoretical ; Peptide Biosynthesis, Nucleic Acid-Independent
Czasopismo naukowe
Tytuł :
4- O -methylascochlorin stabilizes hypoxia-inducible factor-1 in a manner different from hydroxylase inhibition by iron chelating or substrate competition.
Autorzy :
Magae J; Magae Bioscience Institute, Tsukuba, Japan.; Institute of Research and Innovation, Kashiwa, Japan.
Furukawa C; Institute of Research and Innovation, Kashiwa, Japan.
Kuwahara S; Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Jeong YJ; Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea.
Nakajima H; Department of Breast Surgery, Misugi-kai Sato Hospital, Osaka, Japan.
Chang YC; Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea.
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Źródło :
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2019 Dec; Vol. 83 (12), pp. 2244-2248. Date of Electronic Publication: 2019 Aug 08.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Taylor & Francis Country of Publication: England NLM ID: 9205717 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-6947 (Electronic) Linking ISSN: 09168451 NLM ISO Abbreviation: Biosci. Biotechnol. Biochem. Subsets: MEDLINE
MeSH Terms :
Hypoxia-Inducible Factor 1, alpha Subunit/*drug effects
Iron Chelating Agents/*pharmacology
Mixed Function Oxygenases/*metabolism
Terpenes/*pharmacology
Binding, Competitive ; Cell Line, Tumor ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Structure-Activity Relationship ; Substrate Specificity ; Terpenes/chemistry
Czasopismo naukowe
Tytuł :
Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors.
Autorzy :
Gul M; National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Fakhar M; National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Najumuddin; National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Rashid S; National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
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Źródło :
PloS one [PLoS One] 2019 Nov 18; Vol. 14 (11), pp. e0225132. Date of Electronic Publication: 2019 Nov 18 (Print Publication: 2019).
Typ publikacji :
Journal Article
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
Drug Screening Assays, Antitumor*/methods
Quantitative Structure-Activity Relationship*
Adenosine Triphosphate/*chemistry
Protein Kinase Inhibitors/*chemistry
Protein Kinase Inhibitors/*pharmacology
p21-Activated Kinases/*antagonists & inhibitors
p21-Activated Kinases/*chemistry
Amino Acid Sequence ; Binding, Competitive ; Models, Biological ; Models, Molecular ; Molecular Conformation ; Phosphorylation ; Protein Binding ; Protein Isoforms ; p21-Activated Kinases/metabolism
Czasopismo naukowe
Tytuł :
Functional and Nonclinical Similarity of ABP 980, a Biosimilar of Trastuzumab.
Autorzy :
Jassem S; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Wang W; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Sweet H; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Manoukian R; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Chow V; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Kanakaraj P; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Hutterer KM; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Kuhns S; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Foltz IN; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Chen Q; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
Ferbas J; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA.
McBride HJ; Amgen Inc, One Amgen Center Drive, Thousand Oaks, California, 91320, USA. .
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Źródło :
Pharmaceutical research [Pharm Res] 2019 Nov 06; Vol. 36 (12), pp. 177. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm. Res. Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*chemistry
Biosimilar Pharmaceuticals/*chemistry
Trastuzumab/*chemistry
Animals ; Binding, Competitive ; Breast Neoplasms/drug therapy ; Cell Line, Tumor ; Female ; Humans ; Kinetics ; Mice, Nude ; Molecular Structure ; Neoplasms, Experimental ; Protein Binding ; Receptor, ErbB-2/chemistry ; Signal Transduction ; Stomach Neoplasms/drug therapy ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and water in comparison to ten classical perfluoroalkyl acids.
Autorzy :
Allendorf F; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany. .
Berger U; Department of Analytical Chemistry, Helmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.
Goss KU; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany. and Institute of Chemistry, University of Halle-Wittenberg, Kurt-Mothes-Strasse 2, D-06120 Halle, Germany.
Ulrich N; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany. .
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Źródło :
Environmental science. Processes & impacts [Environ Sci Process Impacts] 2019 Nov 01; Vol. 21 (11), pp. 1852-1863. Date of Electronic Publication: 2019 Sep 02.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101601576 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2050-7895 (Electronic) Linking ISSN: 20507887 NLM ISO Abbreviation: Environ Sci Process Impacts Subsets: MEDLINE
MeSH Terms :
Alkanesulfonic Acids/*chemistry
Carboxylic Acids/*chemistry
Fluorocarbons/*chemistry
Serum Albumin, Bovine/*chemistry
Water/*chemistry
Binding, Competitive ; Chromatography, Liquid ; Models, Chemical ; Protein Binding ; Structure-Activity Relationship ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Investigation of binding and activity of perfluoroalkyl substances to the human peroxisome proliferator-activated receptor β/δ.
Autorzy :
Li CH; State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Beijing 100085, China. , University of Chinese Academy of Sciences, Beijing 100039, China.
Ren XM; State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Beijing 100085, China. .
Cao LY; State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Beijing 100085, China. , University of Chinese Academy of Sciences, Beijing 100039, China.
Qin WP; State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Beijing 100085, China. , University of Chinese Academy of Sciences, Beijing 100039, China.
Guo LH; State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Beijing 100085, China. , University of Chinese Academy of Sciences, Beijing 100039, China and The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
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Źródło :
Environmental science. Processes & impacts [Environ Sci Process Impacts] 2019 Nov 01; Vol. 21 (11), pp. 1908-1914. Date of Electronic Publication: 2019 Jul 23.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101601576 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2050-7895 (Electronic) Linking ISSN: 20507887 NLM ISO Abbreviation: Environ Sci Process Impacts Subsets: MEDLINE
MeSH Terms :
Carboxylic Acids/*chemistry
Fluorocarbons/*chemistry
PPAR delta/*chemistry
PPAR-beta/*chemistry
Animals ; Binding, Competitive ; Genes, Reporter ; HEK293 Cells ; Humans ; Ligands ; Luciferases/genetics ; Molecular Docking Simulation ; PPAR delta/genetics ; PPAR delta/metabolism ; PPAR-beta/genetics ; PPAR-beta/metabolism ; Protein Binding ; Structure-Activity Relationship ; Transfection
Czasopismo naukowe
Tytuł :
Insights into the Competition between K + and Pb 2+ Binding to a G-Quadruplex and Discovery of a Novel K + -Pb 2+ -Quadruplex Intermediate.
Autorzy :
Yu Z; College of Chemistry , Beijing Normal University , Beijing 100875 , P. R. China.
Zhou W; College of Chemistry , Beijing Normal University , Beijing 100875 , P. R. China.
Ma G; College of Chemistry , Beijing Normal University , Beijing 100875 , P. R. China.
Li Y; College of Chemistry , Beijing Normal University , Beijing 100875 , P. R. China.
Fan L; College of Chemistry , Beijing Normal University , Beijing 100875 , P. R. China.
Li X; College of Chemistry , Beijing Normal University , Beijing 100875 , P. R. China.
Lu Y; Department of Chemistry, Department of Materials Science and Engineering , University of Illinois at Urbana and Champaign , Urbana , Illinois 61801 , United States.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2018 Oct 11; Vol. 122 (40), pp. 9382-9388. Date of Electronic Publication: 2018 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE
MeSH Terms :
Binding, Competitive*
G-Quadruplexes*
DNA/*metabolism
Lead/*metabolism
Potassium/*metabolism
Circular Dichroism ; DNA/chemistry ; DNA/genetics ; Lead/chemistry ; Potassium/chemistry ; Spectrometry, Mass, Electrospray Ionization ; Thermodynamics
Czasopismo naukowe
Tytuł :
Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase.
Autorzy :
Thompson AP; Molecular and Biomedical Science, The University of Adelaide, North Terrace, Adelaide, South Australia 5005, Australia.
Wegener KL; Institute for Photonics and Advanced Sensing (IPAS), School of Biological Sciences, University of Adelaide, Adelaide, South Australia 5005, Australia.
Booker GW; Molecular and Biomedical Science, The University of Adelaide, North Terrace, Adelaide, South Australia 5005, Australia.
Polyak SW; Molecular and Biomedical Science, The University of Adelaide, North Terrace, Adelaide, South Australia 5005, Australia.
Bruning JB; Institute for Photonics and Advanced Sensing (IPAS), School of Biological Sciences, University of Adelaide, Adelaide, South Australia 5005, Australia.
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Źródło :
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2018 Oct 01; Vol. 74 (Pt 10), pp. 965-972. Date of Electronic Publication: 2018 Oct 02.
Typ publikacji :
Journal Article
Journal Info :
Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101676043 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7983 (Electronic) Linking ISSN: 20597983 NLM ISO Abbreviation: Acta Crystallogr D Struct Biol Subsets: MEDLINE
MeSH Terms :
Binding, Competitive*
Adenosine Diphosphate/*metabolism
Carbon-Nitrogen Ligases/*chemistry
Mycobacterium tuberculosis/*enzymology
Adenosine Diphosphate/pharmacology ; Binding Sites ; Carbon-Nitrogen Ligases/antagonists & inhibitors ; Crystallography, X-Ray ; Cytidine Triphosphate/metabolism ; Ligands ; Protein Binding ; Protein Conformation
Czasopismo naukowe

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