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Wyszukujesz frazę ""Biochimica et biophysica acta [Biochim Biophys Acta] NLMUID: 0217513"" wg kryterium: JN


Tytuł :
Small but smart: MicroRNAs orchestrate atherosclerosis development and progression.
Autorzy :
Santovito D; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Egea V; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Weber C; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1861 (12 Pt B), pp. 2075-2086. Date of Electronic Publication: 2015 Dec 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Atherosclerosis/*genetics
Atherosclerosis/*pathology
MicroRNAs/*genetics
Animals ; Disease Progression ; Gene Expression Regulation/genetics ; Humans ; Lipid Metabolism/genetics
Czasopismo naukowe
Tytuł :
CRISPR-Cas9 therapeutics in cancer: promising strategies and present challenges.
Autorzy :
Yi L; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Beijing, People's Republic of China; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; Beijing Engineering Research Center of Laboratory Medicine, Beijing Hospital, Beijing, People's Republic of China.
Li J; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Beijing, People's Republic of China; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; Beijing Engineering Research Center of Laboratory Medicine, Beijing Hospital, Beijing, People's Republic of China. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1866 (2), pp. 197-207. Date of Electronic Publication: 2016 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
CRISPR-Cas Systems*/physiology
Neoplasms/*therapy
Animals ; Epigenesis, Genetic ; Gene Editing ; Humans ; Immunotherapy ; Molecular Targeted Therapy ; Neoplasms/genetics ; Oncolytic Virotherapy
Czasopismo naukowe
Tytuł :
New Insights into Protein Hydroxylation and Its Important Role in Human Diseases.
Autorzy :
Zurlo G; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Guo J; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
Takada M; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Wei W; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA. Electronic address: .
Zhang Q; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1866 (2), pp. 208-220. Date of Electronic Publication: 2016 Sep 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Prolyl Hydroxylases/*physiology
Proteins/*metabolism
Animals ; Humans ; Hydroxylation
Czasopismo naukowe
Tytuł :
An extensive simulation study of lipid bilayer properties with different head groups, acyl chain lengths, and chain saturations.
Autorzy :
Zhuang X; Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD 20742, USA.
Dávila-Contreras EM; Department of Molecular Biosciences, The University of Kansas, Lawrence, KS 66047, USA.
Beaven AH; Department of Chemistry, The University of Kansas, Lawrence, KS 66047, USA.
Im W; Department of Biological Sciences and Bioengineering Program, Lehigh University, Bethlehem, 18015, USA. Electronic address: .
Klauda JB; Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD 20742, USA; Biophysics Program, University of Maryland, College Park, MD 20742, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1858 (12), pp. 3093-3104. Date of Electronic Publication: 2016 Sep 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Molecular Dynamics Simulation*
Lipid Bilayers/*chemistry
Deuterium ; Glycerophospholipids/chemistry ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Phosphatidylethanolamines/chemistry ; Phosphatidylserines/chemistry ; Temperature
Czasopismo naukowe
Tytuł :
Directed assembly of defined oligomeric photosynthetic reaction centres through adaptation with programmable extra-membrane coiled-coil interfaces.
Autorzy :
Swainsbury DJ; School of Biochemistry, Medical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.
Harniman RL; School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.
Di Bartolo ND; School of Biochemistry, Medical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.
Liu J; School of Biochemistry, Medical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.
Harper WF; School of Biochemistry, Medical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.
Corrie AS; School of Biochemistry, Medical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.
Jones MR; School of Biochemistry, Medical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1857 (12), pp. 1829-1839. Date of Electronic Publication: 2016 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Energy Metabolism*/radiation effects
Photosynthesis*/radiation effects
Bacterial Proteins/*metabolism
Light-Harvesting Protein Complexes/*metabolism
Photosynthetic Reaction Center Complex Proteins/*metabolism
Proteobacteria/*metabolism
Adaptation, Physiological ; Bacterial Proteins/chemistry ; Bacterial Proteins/radiation effects ; Kinetics ; Light ; Light-Harvesting Protein Complexes/chemistry ; Light-Harvesting Protein Complexes/radiation effects ; Molecular Dynamics Simulation ; Photosynthetic Reaction Center Complex Proteins/chemistry ; Photosynthetic Reaction Center Complex Proteins/radiation effects ; Protein Conformation, alpha-Helical ; Protein Multimerization ; Proteobacteria/radiation effects ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Proofreading of substrate structure by the Twin-Arginine Translocase is highly dependent on substrate conformational flexibility but surprisingly tolerant of surface charge and hydrophobicity changes.
Autorzy :
Jones AS; School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom.
Austerberry JI; Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom.
Dajani R; Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom.
Warwicker J; Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom.
Curtis R; School of Chemical Engineering and Analytical Science, University of Manchester, Manchester M13 9PL, United Kingdom.
Derrick JP; Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom.
Robinson C; School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1863 (12), pp. 3116-3124. Date of Electronic Publication: 2016 Sep 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Bacterial*
Transgenes*
Escherichia coli/*genetics
Escherichia coli Proteins/*chemistry
Membrane Transport Proteins/*chemistry
Single-Chain Antibodies/*chemistry
Amino Acid Motifs ; Binding Sites ; Escherichia coli/metabolism ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Humans ; Hydrophobic and Hydrophilic Interactions ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Models, Molecular ; Mutation ; Plasmids/chemistry ; Plasmids/metabolism ; Protein Binding ; Protein Folding ; Protein Interaction Domains and Motifs ; Protein Sorting Signals ; Protein Structure, Secondary ; Protein Transport ; Single-Chain Antibodies/genetics ; Single-Chain Antibodies/metabolism ; Static Electricity ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Macrophage miRNAs in atherosclerosis.
Autorzy :
Karunakaran D; University of Ottawa Heart Institute, Ottawa, Canada.
Rayner KJ; University of Ottawa Heart Institute, Ottawa, Canada; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Canada. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1861 (12 Pt B), pp. 2087-2093. Date of Electronic Publication: 2016 Feb 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Atherosclerosis/*genetics
Macrophages/*metabolism
MicroRNAs/*genetics
Animals ; Atherosclerosis/pathology ; Disease Progression ; Gene Expression Regulation/genetics ; Gene Regulatory Networks/genetics ; Humans ; Lipid Metabolism/genetics
Czasopismo naukowe
Tytuł :
TonB-dependent ligand trapping in the BtuB transporter.
Autorzy :
Mills A; Department of Biochemistry & Molecular Biology, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Le HT; Department of Biochemistry & Molecular Biology, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Duong F; Department of Biochemistry & Molecular Biology, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1858 (12), pp. 3105-3112. Date of Electronic Publication: 2016 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Outer Membrane Proteins/*metabolism
Bacterial Proteins/*metabolism
Escherichia coli Proteins/*metabolism
Membrane Proteins/*metabolism
Membrane Transport Proteins/*metabolism
Vitamin B 12/*metabolism
Bacterial Outer Membrane Proteins/chemistry ; Bacterial Proteins/chemistry ; Binding Sites ; Biological Transport ; Escherichia coli Proteins/chemistry ; Ligands ; Membrane Proteins/chemistry ; Membrane Transport Proteins/chemistry
Czasopismo naukowe
Tytuł :
NAD(+) metabolism: Bioenergetics, signaling and manipulation for therapy.
Autorzy :
Yang Y; Department of Pharmacology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.
Sauve AA; Department of Pharmacology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1864 (12), pp. 1787-1800. Date of Electronic Publication: 2016 Jun 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
NAD/*metabolism
Animals ; Energy Metabolism ; Humans ; Metabolic Diseases/metabolism ; Metabolic Diseases/therapy ; Metabolic Networks and Pathways ; Models, Biological ; NADP/metabolism ; Niacin/metabolism ; Niacinamide/metabolism ; Nucleosides/metabolism ; Signal Transduction ; Sirtuins/metabolism ; Tryptophan/metabolism
Czasopismo naukowe
Tytuł :
Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.
Autorzy :
García-Casarrubios E; Institute of Biomedicine Alberto Sols (CSIC/UAM), E-28029 Madrid, Spain.
de Moura C; Institute of Biomedicine Alberto Sols (CSIC/UAM), E-28029 Madrid, Spain; Center for Neuroscience and Cell Biology, University of Coimbra, E-3000 Coimbra, Portugal.
Arroba AI; Institute of Biomedicine Alberto Sols (CSIC/UAM), E-28029 Madrid, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Spain.
Pescador N; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Spain.
Calderon-Dominguez M; Department of Biochemistry and Physiology, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.
Garcia L; Institute of Biomedicine Alberto Sols (CSIC/UAM), E-28029 Madrid, Spain.
Herrero L; Department of Biochemistry and Physiology, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.
Serra D; Department of Biochemistry and Physiology, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.
Cadenas S; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM) and Departamento de Biología Molecular, Universidad Autónoma de Madrid, 28049 Madrid, Spain; Instituto de Investigación Sanitaria Princesa (IIS-IP), 28006 Madrid, Spain.
Reis F; Center for Neuroscience and Cell Biology, University of Coimbra, E-3000 Coimbra, Portugal; Laboratory of Pharmacology and Experimental Therapeutics, Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, E-3000-548 Coimbra, Portugal.
Carvalho E; Center for Neuroscience and Cell Biology, University of Coimbra, E-3000 Coimbra, Portugal; Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72202, United States; Arkansas Children's Research Institute, Little Rock, AR 72202, United States. Electronic address: .
Obregon MJ; Institute of Biomedicine Alberto Sols (CSIC/UAM), E-28029 Madrid, Spain.
Valverde ÁM; Institute of Biomedicine Alberto Sols (CSIC/UAM), E-28029 Madrid, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Spain. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1861 (12 Pt A), pp. 1929-1941. Date of Electronic Publication: 2016 Sep 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipocytes, Brown/*drug effects
Glucose/*metabolism
Insulin/*metabolism
Signal Transduction/*drug effects
Sirolimus/*pharmacology
Uncoupling Protein 1/*metabolism
Adipocytes, Brown/metabolism ; Adipose Tissue, Brown/drug effects ; Adipose Tissue, Brown/metabolism ; Animals ; Cell Respiration/drug effects ; Gene Expression/drug effects ; Glucose Transporter Type 4/metabolism ; Insulin Receptor Substrate Proteins/metabolism ; Insulin Resistance/physiology ; Male ; Mitochondria/drug effects ; Mitochondria/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Phosphorylation/drug effects ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Thermogenesis/drug effects
Czasopismo naukowe
Tytuł :
Nonsense mediated RNA decay and evolutionary capacitance.
Autorzy :
Raxwal VK; CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
Riha K; CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1859 (12), pp. 1538-1543. Date of Electronic Publication: 2016 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Nonsense Mediated mRNA Decay/*genetics
RNA/*genetics
Transcriptome/*genetics
Codon, Nonsense ; Gene Expression Regulation/genetics ; RNA/biosynthesis ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Correlated trapping of sugar molecules by the trimeric protein channel  chitoporin.
Autorzy :
Suginta W; Biochemistry-Electrochemistry Research Unit, School of Chemistry, Institute of Science, Center of Excellence in Advanced Functional Materials, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Winterhalter M; School of Engineering and Science, Jacobs University Bremen, Bremen, Germany.
Smith MF; School of Physics, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1858 (12), pp. 3032-3040. Date of Electronic Publication: 2016 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Multimerization*
Bacterial Outer Membrane Proteins/*chemistry
Carbohydrates/*chemistry
Porins/*chemistry
Deuterium
Czasopismo naukowe
Tytuł :
Transport of haloacids across biological membranes.
Autorzy :
Su X; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, PR China. Electronic address: .
Li R; Shanghai Quality Safety Centre of Agricultural Products, Shanghai 200335, PR China. Electronic address: .
Kong KF; Molecular Microbiology Laboratory, School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong. Electronic address: .
Tsang JSH; Molecular Microbiology Laboratory, School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1858 (12), pp. 3061-3070. Date of Electronic Publication: 2016 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Dichloroacetic Acid/*pharmacokinetics
Pyruvates/*pharmacokinetics
Animals ; Biological Transport ; Cell Membrane/metabolism ; Humans ; Monocarboxylic Acid Transporters/physiology ; Phylogeny ; Symporters/physiology
Czasopismo naukowe
Tytuł :
Exploring the raft-hypothesis by probing planar bilayer patches of free-standing giant vesicles at nanoscale resolution, with and without Na,K-ATPase.
Autorzy :
Bhatia T; MEMPHYS, University of Southern Denmark, Odense 5230, Denmark. Electronic address: .
Cornelius F; Department of Biomedicine, Aarhus University, 8000, Denmark.
Ipsen JH; MEMPHYS, University of Southern Denmark, Odense 5230, Denmark.
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1858 (12), pp. 3041-3049. Date of Electronic Publication: 2016 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Lipid Bilayers/*chemistry
Membrane Microdomains/*chemistry
Sodium-Potassium-Exchanging ATPase/*chemistry
1,2-Dipalmitoylphosphatidylcholine/chemistry ; Cholesterol/chemistry ; Nanoparticles ; Phosphatidylcholines/chemistry
Czasopismo naukowe
Tytuł :
Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling.
Autorzy :
Cao Y; Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin University, Changchun 130012, China; College of Life Science, Jilin University, Changchun 130012, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
Guan K; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
He X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
Wei C; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
Zheng Z; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
Zhang Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
Ma S; Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin University, Changchun 130012, China; College of Life Science, Jilin University, Changchun 130012, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
Zhong H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address: .
Shi W; Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin University, Changchun 130012, China; College of Life Science, Jilin University, Changchun 130012, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1863 (12), pp. 3148-3159. Date of Electronic Publication: 2016 Oct 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immune Evasion*
Bacterial Proteins/*genetics
DNA/*genetics
Interferon Regulatory Factor-3/*genetics
Membrane Proteins/*genetics
Yersinia pestis/*genetics
Animals ; Bacterial Proteins/immunology ; Cell Line ; DNA/immunology ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum/microbiology ; Gene Deletion ; Gene Expression Regulation ; Golgi Apparatus/metabolism ; Golgi Apparatus/microbiology ; HEK293 Cells ; Humans ; Immunity, Innate ; Interferon Regulatory Factor-3/immunology ; Interferon-beta/genetics ; Interferon-beta/immunology ; Macrophages/immunology ; Macrophages/microbiology ; Membrane Proteins/immunology ; Mice ; Phosphorylation ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/immunology ; Signal Transduction ; Ubiquitination ; Yersinia pestis/growth & development ; Yersinia pestis/pathogenicity
Czasopismo naukowe
Tytuł :
Means to the ends: The role of telomeres and telomere processing machinery in metastasis.
Autorzy :
Robinson NJ; Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.
Schiemann WP; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1866 (2), pp. 320-329. Date of Electronic Publication: 2016 Oct 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neoplasm Metastasis*
Telomere/*physiology
Animals ; Homologous Recombination ; Humans ; Telomerase/physiology ; Telomere Homeostasis
Czasopismo naukowe
Tytuł :
Privileged crosstalk between TRPV1 channels and mitochondrial calcium shuttling machinery controls nociception.
Autorzy :
Nita II; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Israel.
Caspi Y; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University, Jerusalem 91120, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem 91120, Israel.
Gudes S; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University, Jerusalem 91120, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem 91120, Israel.
Fishman D; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Israel.
Lev S; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University, Jerusalem 91120, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem 91120, Israel.
Hersfinkel M; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Israel.
Sekler I; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Israel. Electronic address: .
Binshtok AM; Department of Medical Neurobiology, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University, Jerusalem 91120, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem 91120, Israel. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1863 (12), pp. 2868-2880. Date of Electronic Publication: 2016 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Calcium Channels/*metabolism
Nociceptors/*metabolism
Sodium/*metabolism
Sodium-Calcium Exchanger/*metabolism
TRPV Cation Channels/*metabolism
Action Potentials/drug effects ; Action Potentials/physiology ; Animals ; Calcium Channels/genetics ; Capsaicin/pharmacology ; Egtazic Acid/analogs & derivatives ; Egtazic Acid/pharmacology ; Ganglia, Spinal/cytology ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; Gene Expression Regulation ; HEK293 Cells ; Humans ; Male ; Membrane Potential, Mitochondrial/drug effects ; Membrane Potential, Mitochondrial/physiology ; Mitochondrial Proteins ; Molecular Imaging ; Nociceptors/cytology ; Nociceptors/drug effects ; Primary Cell Culture ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Rats ; Rats, Sprague-Dawley ; Single-Cell Analysis ; Sodium-Calcium Exchanger/antagonists & inhibitors ; Sodium-Calcium Exchanger/genetics ; TRPV Cation Channels/antagonists & inhibitors ; TRPV Cation Channels/genetics
Czasopismo naukowe
Tytuł :
BET bromodomain is a novel regulator of TAZ and its activity.
Autorzy :
Duan Q; Cardiovascular Division, Xiangya Hospital, Central South University, Changsha, China.
Xiao Y; Cardiovascular Division, Xiangya Hospital, Central South University, Changsha, China.
Zhu L; Department of Endocrinology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Liu Z; Cardiovascular Division, Xiangya Hospital, Central South University, Changsha, China.
Mao X; Cardiovascular Division, Xiangya Hospital, Central South University, Changsha, China; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Zhou Z; Cardiovascular Division, Xiangya Hospital, Central South University, Changsha, China.
Liao C; Department of Histology and Embryology, Xiangya School of Medicine, Central South University, 172 Tongzipo Road, Changsha, China.
Cai J; Department of Histology and Embryology, Xiangya School of Medicine, Central South University, 172 Tongzipo Road, Changsha, China.
Huang F; Department of Anatomy and Neuroscience, Xiangya School of Medicine, Central South University, Changsha, China.
Liu Z; Endocrinology Division, Xiangya Hospital, Central South University, Changsha, China.
Zeng J; Department of Thoracic Surgery, Yiyang Central Hospital, Yiyang, China.
Xia K; Cardiovascular Division, Xiangya Hospital, Central South University, Changsha, China.
Chang C; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, United States.
Qi J; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, United States.
Chen Z; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China. Electronic address: .
Huang H; Department of Histology and Embryology, Xiangya School of Medicine, Central South University, 172 Tongzipo Road, Changsha, China; Digestive Cancer Laboratory, Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830063, China. Electronic address: .
Yang T; Cardiovascular Division, Xiangya Hospital, Central South University, Changsha, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1859 (12), pp. 1527-1537. Date of Electronic Publication: 2016 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colonic Neoplasms/*genetics
Nuclear Proteins/*genetics
Proteins/*genetics
Transcription Factors/*genetics
Transcriptional Activation/*genetics
Animals ; Cell Cycle Checkpoints/genetics ; Cell Proliferation/genetics ; Colonic Neoplasms/pathology ; Gene Expression Regulation, Neoplastic/genetics ; HCT116 Cells ; Humans ; Mice ; Nuclear Proteins/biosynthesis ; Signal Transduction ; Transcription Factors/biosynthesis ; Wnt Signaling Pathway ; Xenograft Model Antitumor Assays ; beta Catenin/genetics
Czasopismo naukowe
Tytuł :
Insight into the oligomeric structure of PORA from A. thaliana.
Autorzy :
Gabruk M; Department of Plant Physiology and Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland. Electronic address: .
Nowakowska Z; Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Skupien-Rabian B; Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland; Department of Structural Biology, Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, 30-387 Kraków, Poland.
Kędracka-Krok S; Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland; Department of Structural Biology, Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, 30-387 Kraków, Poland.
Mysliwa-Kurdziel B; Department of Plant Physiology and Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Kruk J; Department of Plant Physiology and Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1864 (12), pp. 1757-1764. Date of Electronic Publication: 2016 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arabidopsis Proteins/*chemistry
Oxidoreductases Acting on CH-CH Group Donors/*chemistry
Arabidopsis/enzymology ; Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Catalytic Domain ; Cross-Linking Reagents ; Fluorescence Resonance Energy Transfer ; Mass Spectrometry ; Models, Molecular ; Mutagenesis, Site-Directed ; Oxidoreductases Acting on CH-CH Group Donors/genetics ; Oxidoreductases Acting on CH-CH Group Donors/metabolism ; Protein Multimerization ; Protein Structure, Quaternary ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism
Czasopismo naukowe
Tytuł :
miRNA and cholesterol homeostasis.
Autorzy :
Jeon TI; Department of Animal Science, Chonnam National University, Gwangju 61186, South Korea.
Osborne TF; Integrative Metabolism Program, Sanford.Burnham.Prebys Medical Discovery Institute, Orlando, FL, United States. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Dec; Vol. 1861 (12 Pt B), pp. 2041-2046. Date of Electronic Publication: 2016 Jan 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cholesterol/*genetics
Homeostasis/*genetics
MicroRNAs/*genetics
Animals ; Energy Metabolism/genetics ; Gene Regulatory Networks/genetics ; Humans ; Lipid Metabolism/genetics ; Metabolic Diseases/genetics ; Transcription Factors/genetics
Czasopismo naukowe

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