Temat: "Biological Availability" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Melatonin improves nitric oxide bioavailability in isoproterenol induced myocardial injury.
Autorzy:: Santos R; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Turck P; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
de Mello Palma V; Faculdade de Odontologia. Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2492 - Santa Cecília, CEP: 90035-004, Porto Alegre, RS, Brazil.
Visioli F; Faculdade de Odontologia. Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2492 - Santa Cecília, CEP: 90035-004, Porto Alegre, RS, Brazil.
Ortiz VD; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Proença ICT; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Fernandes TRG; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Fernandes E; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Tasca S; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Carraro CC; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Belló-Klein A; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
da Rosa Araujo AS; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil.
Khaper N; Northern Ontario School of Medicine University, 955 Oliver Road, Thunder Bay, ON, Canada.
de Castro AL; Laboratory of Cardiovascular Physiology and Reactive Oxygen Species, Physiology Department, Institute of Basic Health Science (ICBS), Federal University of Rio Grande do Sul (UFRGS), Ramiro Barcelos Street, 2600 - Santa Cecília, CEP: 90035-003, Porto Alegre, RS, Brazil. Electronic address: .; Pokaż więcej
Źródło:: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2024 Sep 15; Vol. 591, pp. 112279. Date of Electronic Publication: 2024 May 24.
Typ publikacji:: Journal Article
MeSH Terms:: Isoproterenol*
Melatonin*/pharmacology
Nitric Oxide*/metabolism
Rats, Wistar*
Biological Availability*
Animals ; Male ; Rats ; Cardiotonic Agents/pharmacology ; Myocardium/metabolism ; Myocardium/pathology ; NF-kappa B/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Interleukin-1beta/metabolism ; Heart Injuries/metabolism ; Heart Injuries/chemically induced ; Heart Injuries/pathology

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Tytuł:: Pharmacokinetics and Bioavailability Study of a Novel Smoothened Inhibitor TPB15 for Treatment of Triple-Negative Breast Cancer in Rats by High Performance Liquid Chromatography-Mass Spectrometry.
Autorzy:: Chen BY; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Xu JH; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Chen QQ; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Wu HX; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Ou BF; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Zhou Z; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, 510080, China.
Xu F; School of Biological Science and Engineering, South China University of Technology, Guangzhou, 511436, China.
Wu SY; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. .
Xie SL; School of Biological Science and Engineering, South China University of Technology, Guangzhou, 511436, China. .
Wen DS; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, 510080, China. wen_.; Pokaż więcej
Źródło:: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2024 Sep; Vol. 49 (5), pp. 645-655. Date of Electronic Publication: 2024 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Biological Availability*
Triple Negative Breast Neoplasms*/drug therapy
Rats, Sprague-Dawley*
Smoothened Receptor*/antagonists & inhibitors
Tandem Mass Spectrometry*/methods
Pyridines*/pharmacokinetics
Pyridines*/administration & dosage
Animals ; Rats ; Female ; Chromatography, High Pressure Liquid/methods ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/administration & dosage ; Administration, Oral ; Liquid Chromatography-Mass Spectrometry

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Tytuł:: Kappa-carrageenan in a pork-based high-fat diet inhibited lipid bioavailability through interactions with pork protein.
Autorzy:: Huang Z; State Key Laboratory of Meat Quality Control and Cultured Meat Development, MOST; Key Laboratory of Meat Processing, MOA, Jiangsu Synergetic Innovation Center of Meat Production, Processing and Quality Control, Nanjing Agricultural University; Nanjing 210095, PR China; Institute of Food Science and Technology, Fujian Academy of Agricultural Science, Fuzhou, Fujian 350002, PR China.
Ding M; State Key Laboratory of Meat Quality Control and Cultured Meat Development, MOST; Key Laboratory of Meat Processing, MOA, Jiangsu Synergetic Innovation Center of Meat Production, Processing and Quality Control, Nanjing Agricultural University; Nanjing 210095, PR China.
Xie Y; State Key Laboratory of Meat Quality Control and Cultured Meat Development, MOST; Key Laboratory of Meat Processing, MOA, Jiangsu Synergetic Innovation Center of Meat Production, Processing and Quality Control, Nanjing Agricultural University; Nanjing 210095, PR China.
Chen B; Institute of Food Science and Technology, Fujian Academy of Agricultural Science, Fuzhou, Fujian 350002, PR China.
Zhao D; State Key Laboratory of Meat Quality Control and Cultured Meat Development, MOST; Key Laboratory of Meat Processing, MOA, Jiangsu Synergetic Innovation Center of Meat Production, Processing and Quality Control, Nanjing Agricultural University; Nanjing 210095, PR China.
Li C; State Key Laboratory of Meat Quality Control and Cultured Meat Development, MOST; Key Laboratory of Meat Processing, MOA, Jiangsu Synergetic Innovation Center of Meat Production, Processing and Quality Control, Nanjing Agricultural University; Nanjing 210095, PR China. Electronic address: .; Pokaż więcej
Źródło:: International journal of biological macromolecules [Int J Biol Macromol] 2024 Sep; Vol. 276 (Pt 2), pp. 133922. Date of Electronic Publication: 2024 Jul 18.
Typ publikacji:: Journal Article
MeSH Terms:: Carrageenan*
Biological Availability*
Diet, High-Fat*
Lipolysis*/drug effects
Animals ; Swine ; Meat Proteins/metabolism ; Lipid Metabolism/drug effects ; Protein Hydrolysates/pharmacology ; Protein Hydrolysates/chemistry ; Digestion/drug effects ; Lipids/chemistry ; Pork Meat/analysis

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Tytuł:: Increased oxygen content in biochar lowered bioavailability of polycyclic aromatic hydrocarbons-related toxicity to various organisms.
Autorzy:: Sokołowski A; Department of Radiochemistry and Environmental Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University in Lublin, Pl. M. Curie-Sklodowskiej 3, 20-031 Lublin, Poland.
Boguszewska-Czubara A; Chair and Department of Medical Chemistry, Medical University of Lublin, Ul. Chodźki 4a, 20-093 Lublin, Poland.
Kobyłecki R; Department of Advanced Energy Technologies, Częstochowa University of Technology, Dąbrowskiego 73, 42-201 Częstochowa, Poland.
Zarzycki R; Department of Advanced Energy Technologies, Częstochowa University of Technology, Dąbrowskiego 73, 42-201 Częstochowa, Poland.
Kończak M; Department of Hydrology and Climatology, Institute of Earth and Environmental Sciences, Faculty of Earth Sciences and Spatial Management, Maria Curie-Skłodowska University, Al. Kraśnickie 2d, 20-718 Lublin, Poland.
Oleszczuk P; Department of Radiochemistry and Environmental Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University in Lublin, Pl. M. Curie-Sklodowskiej 3, 20-031 Lublin, Poland.
Gao Y; Institute of Organic Contaminant Control and Soil Remediation, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Czech B; Department of Radiochemistry and Environmental Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University in Lublin, Pl. M. Curie-Sklodowskiej 3, 20-031 Lublin, Poland; Chair and Department of Medical Chemistry, Medical University of Lublin, Ul. Chodźki 4a, 20-093 Lublin, Poland. Electronic address: .; Pokaż więcej
Źródło:: Bioresource technology [Bioresour Technol] 2024 Sep; Vol. 407, pp. 131110. Date of Electronic Publication: 2024 Jul 14.
Typ publikacji:: Journal Article
MeSH Terms:: Charcoal*/chemistry
Polycyclic Aromatic Hydrocarbons*
Oxygen*/chemistry
Biological Availability*
Animals ; Pyrolysis

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Skocz do pozycji: 5.

Tytuł:: Evaluation of the pharmacokinetics, chylomicron inhibition, and toxicity of colchicine in rats given low doses.
Autorzy:: Al Nebaihi HM; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alverta, Edmonton, Alberta, Canada.
Davies NM; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alverta, Edmonton, Alberta, Canada.
Brocks DR; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alverta, Edmonton, Alberta, Canada. Electronic address: .; Pokaż więcej
Źródło:: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Sep; Vol. 202, pp. 114392. Date of Electronic Publication: 2024 Jul 06.
Typ publikacji:: Journal Article
MeSH Terms:: Rats, Sprague-Dawley*
Colchicine*/pharmacokinetics
Colchicine*/administration & dosage
Colchicine*/toxicity
Chylomicrons*/metabolism
Biological Availability*
Animals ; Male ; Rats ; Administration, Oral ; Intestinal Absorption/drug effects ; Dose-Response Relationship, Drug ; Tandem Mass Spectrometry/methods ; Peanut Oil/administration & dosage ; Peanut Oil/pharmacokinetics ; Peanut Oil/toxicity ; Cholesterol

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Tytuł:: Comparing the antioxidation and bioavailability of polysaccharides from extruded and unextruded Baijiu vinasses via in vitro digestion and fecal fermentation.
Autorzy:: Liu Y; School of Environmental Science and Engineering, Tianjin University, Tianjin 300350, China.
Li X; Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, Guangdong 511458, China.
Qin H; National Engineering Research Center of Solid-State Brewing, Luzhou, Sichuan 646000, China.
Huang M; National Engineering Research Center of Solid-State Brewing, Luzhou, Sichuan 646000, China.
Xi B; School of Environmental Science and Engineering, Tianjin University, Tianjin 300350, China; State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.
Mao J; National Engineering Research Center of Solid-State Brewing, Luzhou, Sichuan 646000, China; National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China. Electronic address: .
Zhang S; National Engineering Research Center of Solid-State Brewing, Luzhou, Sichuan 646000, China.; Pokaż więcej
Źródło:: International journal of biological macromolecules [Int J Biol Macromol] 2024 Sep; Vol. 276 (Pt 2), pp. 133681. Date of Electronic Publication: 2024 Jul 04.
Typ publikacji:: Journal Article; Comparative Study
MeSH Terms:: Antioxidants*/pharmacokinetics
Antioxidants*/pharmacology
Antioxidants*/chemistry
Fermentation*
Polysaccharides*/chemistry
Feces*/chemistry
Feces*/microbiology
Biological Availability*
Digestion ; Fatty Acids, Volatile/metabolism ; Gastrointestinal Microbiome/drug effects ; Monosaccharides ; Humans

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Skocz do pozycji: 7.

Tytuł:: Comparison of two self-nanoemulsifying drug delivery systems using different solidification techniques for enhanced solubility and oral bioavailability of poorly water-soluble celecoxib.
Autorzy:: Woo MR; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Woo S; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Bak YW; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Cheon S; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Kim JS; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Ji SH; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Park S; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Kim JO; College of Pharmacy, Yeungnam University, 214-1, Dae-Dong, Gyongsan 712-749, South Korea.
Jin SG; Department of Pharmaceutical Engineering, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, South Korea. Electronic address: .
Choi HG; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea. Electronic address: .; Pokaż więcej
Źródło:: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2024 Sep; Vol. 241, pp. 114044. Date of Electronic Publication: 2024 Jun 17.
Typ publikacji:: Journal Article; Comparative Study
MeSH Terms:: Celecoxib*/chemistry
Celecoxib*/pharmacokinetics
Celecoxib*/administration & dosage
Solubility*
Biological Availability*
Emulsions*/chemistry
Rats, Sprague-Dawley*
Water*/chemistry
Drug Delivery Systems*
Animals ; Administration, Oral ; Male ; Rats ; Particle Size ; Surface-Active Agents/chemistry ; Nanoparticles/chemistry ; Polysorbates/chemistry

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Skocz do pozycji: 8.

Tytuł:: Enhanced Bioavailability and Reduced Variability of Dasatinib and Sorafenib with a Novel Amorphous Solid Dispersion Technology Platform.
Autorzy:: Lennernäs H; Department of Pharmaceutical Biosciences, Translational Drug Discovery and Development, Uppsala University, Uppsala, Sweden.
Brisander M; Xspray Pharma AB, Solna, Sweden.
Liljebris C; Xspray Pharma AB, Solna, Sweden.
Jesson G; Xspray Pharma AB, Solna, Sweden.
Andersson P; Xspray Pharma AB, Solna, Sweden.; Pokaż więcej
Źródło:: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2024 Sep; Vol. 13 (9), pp. 985-999. Date of Electronic Publication: 2024 May 29.
Typ publikacji:: Journal Article; Randomized Controlled Trial; Comparative Study
MeSH Terms:: Dasatinib*/pharmacokinetics
Dasatinib*/administration & dosage
Sorafenib*/pharmacokinetics
Sorafenib*/administration & dosage
Biological Availability*
Protein Kinase Inhibitors*/pharmacokinetics
Protein Kinase Inhibitors*/administration & dosage
Protein Kinase Inhibitors*/blood
Humans ; Male ; Administration, Oral ; Nanoparticles ; Solubility ; Adult ; Therapeutic Equivalency ; Drug Compounding ; Tablets ; Young Adult ; Cross-Over Studies ; Female

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Skocz do pozycji: 9.

Tytuł:: Effect of baking on the structure and bioavailability of protein-binding zinc from oyster (Crassoetrea hongkongensis).
Autorzy:: Song C; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Zhong R; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Zeng S; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Chen Z; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.; National Research and Development Branch Center for Shellfish Processing (Zhanjiang), Zhanjiang 524088, China.; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Zhanjiang 524088, China.; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Tan M; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.; National Research and Development Branch Center for Shellfish Processing (Zhanjiang), Zhanjiang 524088, China.; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Zhanjiang 524088, China.; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Zheng H; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.; National Research and Development Branch Center for Shellfish Processing (Zhanjiang), Zhanjiang 524088, China.; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Zhanjiang 524088, China.; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Gao J; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.; National Research and Development Branch Center for Shellfish Processing (Zhanjiang), Zhanjiang 524088, China.; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Zhanjiang 524088, China.; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Lin H; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.; National Research and Development Branch Center for Shellfish Processing (Zhanjiang), Zhanjiang 524088, China.; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Zhanjiang 524088, China.; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Zhu G; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.; National Research and Development Branch Center for Shellfish Processing (Zhanjiang), Zhanjiang 524088, China.; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Zhanjiang 524088, China.; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Cao W; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.; National Research and Development Branch Center for Shellfish Processing (Zhanjiang), Zhanjiang 524088, China.; Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Zhanjiang 524088, China.; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.. Electronic address: .; Pokaż więcej
Źródło:: Food chemistry [Food Chem] 2024 Sep 01; Vol. 451, pp. 139471. Date of Electronic Publication: 2024 Apr 25.
Typ publikacji:: Journal Article
MeSH Terms:: Biological Availability*
Zinc*/metabolism
Zinc*/chemistry
Ostreidae*/chemistry
Ostreidae*/metabolism
Humans ; Caco-2 Cells ; Animals ; Cooking ; Carrier Proteins/chemistry ; Carrier Proteins/metabolism ; Hot Temperature ; Protein Binding ; Shellfish/analysis

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Skocz do pozycji: 10.

Tytuł:: Enhancing vitamin D 3 bioaccessibility: Unveiling hydrophobic interactions in soybean protein isolate and vitamin D 3 binding via an infant in vitro digestion model.
Autorzy:: Huang JR; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, Liaoning Province Key Laboratory for Marine Food Science and Technology, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Song JR; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, Liaoning Province Key Laboratory for Marine Food Science and Technology, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Cai WS; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, Liaoning Province Key Laboratory for Marine Food Science and Technology, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Shao ZW; Qingdao Seawit Life Science Co., Ltd., Qingdao 370200, China.
Zhou DY; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, Liaoning Province Key Laboratory for Marine Food Science and Technology, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Song L; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, Liaoning Province Key Laboratory for Marine Food Science and Technology, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China. Electronic address: .; Pokaż więcej
Źródło:: Food chemistry [Food Chem] 2024 Sep 01; Vol. 451, pp. 139507. Date of Electronic Publication: 2024 Apr 29.
Typ publikacji:: Journal Article
MeSH Terms:: Soybean Proteins*/chemistry
Soybean Proteins*/metabolism
Hydrophobic and Hydrophilic Interactions*
Digestion*
Cholecalciferol*/chemistry
Cholecalciferol*/metabolism
Biological Availability*
Humans ; Infant ; Models, Biological ; Nanoparticles/chemistry ; Nanoparticles/metabolism

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Skocz do pozycji: 11.

Tytuł:: Mirtazapine loaded polymeric micelles for rapid release tablet: A novel formulation-In vitro and in vivo studies.
Autorzy:: El-Helaly SN; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt. .
Rashad AA; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Heliopolis University, El Salam City, Cairo, Egypt.; Pokaż więcej
Źródło:: Drug delivery and translational research [Drug Deliv Transl Res] 2024 Sep; Vol. 14 (9), pp. 2488-2498. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Micelles*
Mirtazapine*/pharmacokinetics
Mirtazapine*/administration & dosage
Mirtazapine*/chemistry
Tablets*
Solubility*
Biological Availability*
Animals ; Rabbits ; Male ; Drug Liberation ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/pharmacokinetics ; Polyethylene Glycols/administration & dosage ; Polymers/chemistry ; Particle Size ; Surface-Active Agents/chemistry ; Administration, Oral ; Stearic Acids/chemistry ; Stearic Acids/pharmacokinetics ; Chemistry, Pharmaceutical/methods

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Skocz do pozycji: 12.

Tytuł:: Exploring the formation mechanism of ferulic acid/hydroxypropyl-β-cyclodextrin inclusion complex: spectral analyses and computer simulation.
Autorzy:: Lv J; School of Life Science & Technology, Inner Mongolia University of Science & Technology, Baotou, China.
Tan M; School of Life Science & Technology, Inner Mongolia University of Science & Technology, Baotou, China.
Zou J; School of Life Science & Technology, Inner Mongolia University of Science & Technology, Baotou, China.
Yun Y; School of Life Science & Technology, Inner Mongolia University of Science & Technology, Baotou, China.
Ren Y; School of Life Science & Technology, Inner Mongolia University of Science & Technology, Baotou, China.
Guo F; School of Life Science & Technology, Inner Mongolia University of Science & Technology, Baotou, China.
Wang G; School of Life Science & Technology, Inner Mongolia University of Science & Technology, Baotou, China.; Pokaż więcej
Źródło:: Journal of the science of food and agriculture [J Sci Food Agric] 2024 Aug 30; Vol. 104 (11), pp. 6584-6593. Date of Electronic Publication: 2024 Apr 12.
Typ publikacji:: Journal Article
MeSH Terms:: Coumaric Acids*/chemistry
2-Hydroxypropyl-beta-cyclodextrin*/chemistry
Solubility*
Computer Simulation*
Biological Availability*
Spectroscopy, Fourier Transform Infrared ; X-Ray Diffraction ; Molecular Dynamics Simulation ; Hydrophobic and Hydrophilic Interactions ; Thermogravimetry

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Tytuł:: Presence of Modified Peptides with High Bioavailability and Angiotensin-Converting Enzyme Inhibitory Activity in Japanese Fermented Soybean Paste ( Miso ).
Autorzy:: Nagao A; Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kitashirakawaoiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan.
Nakamoto Y; Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kitashirakawaoiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan.
Miyauchi S; Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kitashirakawaoiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan.
Sato K; Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kitashirakawaoiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan.; Pokaż więcej
Źródło:: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Aug 28; Vol. 72 (34), pp. 18942-18956. Date of Electronic Publication: 2024 Aug 15.
Typ publikacji:: Journal Article
MeSH Terms:: Angiotensin-Converting Enzyme Inhibitors*/chemistry
Angiotensin-Converting Enzyme Inhibitors*/metabolism
Angiotensin-Converting Enzyme Inhibitors*/administration & dosage
Biological Availability*
Fermentation*
Peptides*/chemistry
Soy Foods*/analysis
Animals ; Male ; Rats ; Glycine max/chemistry ; Japan ; Peptidyl-Dipeptidase A/metabolism ; Peptidyl-Dipeptidase A/chemistry ; Rats, Sprague-Dawley

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Skocz do pozycji: 14.

Tytuł:: Isolation, Purification of Phenolic Glycoside 1 from Moringa oleifera Seeds and Formulation of Its Liposome Delivery System.
Autorzy:: Shi F; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Gong M; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Adu-Frimpong M; Department of Biochemistry and Forensic Sciences, School Chemical and Biochemical Sciences, C. K. Tedam University of Technology and Applied Sciences (CKT-UTAS), UK 0215-5321, Navrongo, Ghana.
Jiang X; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Wang X; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Hua Q; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Li T; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Li J; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Yu J; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Toreniyazov E; Tashkent State Agricultural University (Nukus Branch), Nukus, Uzbekistan.
Cao X; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China. .
Wang Q; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China. .
Xu X; Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China. .; Pokaż więcej
Źródło:: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Aug 22; Vol. 25 (7), pp. 196. Date of Electronic Publication: 2024 Aug 22.
Typ publikacji:: Journal Article
MeSH Terms:: Liposomes*
Moringa oleifera*/chemistry
Seeds*/chemistry
Glycosides*/chemistry
Glycosides*/administration & dosage
Glycosides*/pharmacology
Glycosides*/isolation & purification
Biological Availability*
Phenols*/administration & dosage
Phenols*/chemistry
Phenols*/isolation & purification
Phenols*/pharmacokinetics
Humans ; Animals ; Hep G2 Cells ; Particle Size ; Drug Delivery Systems/methods ; Mice ; Male ; Rats ; Administration, Oral ; Chemistry, Pharmaceutical/methods ; Rats, Sprague-Dawley

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Tytuł:: Radioactive ADME Demonstrates ARV-110's High Druggability Despite Low Oral Bioavailability.
Autorzy:: He Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of the Chinese Academy of Sciences, Beijing 100049, China.
Zheng Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Zhu C; Wuxi Beita Pharmatech Co., Ltd., Wuxi 214437, China.
Lei P; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Yu J; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Tang C; XenoFinder Co., Ltd., Suzhou 215123, China.
Chen H; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of the Chinese Academy of Sciences, Beijing 100049, China.
Diao X; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of the Chinese Academy of Sciences, Beijing 100049, China.; XenoFinder Co., Ltd., Suzhou 215123, China.; Pokaż więcej
Źródło:: Journal of medicinal chemistry [J Med Chem] 2024 Aug 22; Vol. 67 (16), pp. 14277-14291. Date of Electronic Publication: 2024 Jul 29.
Typ publikacji:: Journal Article
MeSH Terms:: Biological Availability*
Animals ; Male ; Administration, Oral ; Rats ; Humans ; Rats, Sprague-Dawley ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/chemistry ; Prostatic Neoplasms/drug therapy ; Proteolysis/drug effects ; Carbon Radioisotopes ; Tissue Distribution ; Cell Line, Tumor ; Mice

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Skocz do pozycji: 16.

Tytuł:: Improvement of Bioavailability of Sildenafil Citrate Through Taste Masked Orodispersible Film for Pulmonary Hypertension Management.
Autorzy:: Mewada V; Department of Pharmaceutics, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, India.
Shah J; Department of Pharmaceutics, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, India. .
Jacob S; Department of Pharmaceutical Sciences, College of Pharmacy, Gulf Medical University, 4184, Ajman, United Arab Emirates.
Shah H; Department of Pharmaceutics, Parul College of Pharmacy and Research, Parul University, Ahmedabad, 380058, India.
Boddu SHS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman University, 346, Ajman, United Arab Emirates.
Nair AB; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, 31982, Al-Ahsa, Saudi Arabia.; Pokaż więcej
Źródło:: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Aug 21; Vol. 25 (7), pp. 194. Date of Electronic Publication: 2024 Aug 21.
Typ publikacji:: Journal Article
MeSH Terms:: Sildenafil Citrate*/pharmacokinetics
Sildenafil Citrate*/administration & dosage
Biological Availability*
Taste*
Drug Liberation*
Hypertension, Pulmonary*/drug therapy
Solubility*
Animals ; Administration, Oral ; Rats ; Male ; Rats, Wistar ; Vasodilator Agents/pharmacokinetics ; Vasodilator Agents/administration & dosage ; Chemistry, Pharmaceutical/methods ; Drug Delivery Systems/methods

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Skocz do pozycji: 17.

Tytuł:: The Synthesis of SNAC Phenolate Salts and the Effect on Oral Bioavailability of Semaglutide.
Autorzy:: Shapira-Furman T; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, P.O. Box 12065, Jerusalem 91120, Israel.
Bar-Hai A; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, P.O. Box 12065, Jerusalem 91120, Israel.
Hoffman A; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, P.O. Box 12065, Jerusalem 91120, Israel.
Domb AJ; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, P.O. Box 12065, Jerusalem 91120, Israel.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Aug 19; Vol. 29 (16). Date of Electronic Publication: 2024 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Glucagon-Like Peptides*/pharmacokinetics
Glucagon-Like Peptides*/administration & dosage
Glucagon-Like Peptides*/chemistry
Biological Availability*
Caprylates*/chemistry
Administration, Oral ; Animals ; Salts/chemistry ; Rats ; Male

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Skocz do pozycji: 18.

Tytuł:: Physicochemical Stimuli-Mediated Precipitation Approach for the Modulation of Rifampicin's Dissolution and Oral Bioavailability.
Autorzy:: Rai VK; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Pradhan D; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Halder J; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Rajwar TK; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Mahanty R; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Saha I; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Dash P; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Dash C; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Rout SK; LNK International Inc, Hauppauge, New York, 11788, USA.
Al-Tamimi J; Zoology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh, Saudi Arabia.
Ebaid H; Zoology Department, College of Science, King Saud University, P.O. Box 2455, Riyadh, Saudi Arabia.
Manoharadas S; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box. 2454, 11451, Riyadh, Saudi Arabia.
Kar B; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Ghosh G; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Rath G; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India. .; Pokaż więcej
Źródło:: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Aug 19; Vol. 25 (7), pp. 189. Date of Electronic Publication: 2024 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Rifampin*/pharmacokinetics
Rifampin*/chemistry
Rifampin*/administration & dosage
Biological Availability*
Drug Liberation*
Solubility*
Administration, Oral ; Animals ; Humans ; Chemical Precipitation ; Hydrophobic and Hydrophilic Interactions ; Serum Albumin, Human/chemistry ; Nanoparticles/chemistry ; Rats ; Protein Binding ; Male ; Ammonium Sulfate/chemistry

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Tytuł:: Comparison of the In Vitro Iron Bioavailability of Tempeh Made with Tenebrio molitor to Beef and Plant-Based Meat Alternatives.
Autorzy:: Wilson JW; Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA.
Thompson TW; Department of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Wei Y; Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA.
Chaparro JM; Analytical Resources Core, Bioanalysis and Omics (ARC-BIO), Colorado State University, Fort Collins, CO 80523, USA.
Stull VJ; Center for Sustainability and the Global Environment, University of Wisconsin-Madison, Madison, WI 53726, USA.
Nair MN; Department of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Weir TL; Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA.; Pokaż więcej
Źródło:: Nutrients [Nutrients] 2024 Aug 18; Vol. 16 (16). Date of Electronic Publication: 2024 Aug 18.
Typ publikacji:: Journal Article; Comparative Study
MeSH Terms:: Tenebrio*
Biological Availability*
Iron*/metabolism
Iron*/pharmacokinetics
Animals ; Humans ; Caco-2 Cells ; Cattle ; Iron, Dietary/pharmacokinetics ; Red Meat/analysis ; Edible Insects/chemistry ; Meat Substitutes

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Tytuł:: Stability and Bioaccessibility of Carotenoids from Sea Buckthorn Pomace Encapsulated in Alginate Hydrogel Beads.
Autorzy:: Gherasim CE; Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine, Mănăştur Street 3-5, 400372 Cluj-Napoca, Romania.
Focşan M; Biomolecular Physics Department, Faculty of Physics, Babeș-Bolyai University, 1 Mihail Kogalniceanu Str., 400084 Cluj-Napoca, Romania.; Nanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babeș-Bolyai University, Treboniu Laurean Street, 42, 400271 Cluj-Napoca, Romania.
Ciont C; Institute of Life Sciences, University of Agricultural Science and Veterinary Medicine, Calea Mănăstur 3-5, 400372 Cluj-Napoca, Romania.
Bunea A; Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine, Mănăştur Street 3-5, 400372 Cluj-Napoca, Romania.
Rugină D; Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine, Mănăştur Street 3-5, 400372 Cluj-Napoca, Romania.
Pintea A; Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine, Mănăştur Street 3-5, 400372 Cluj-Napoca, Romania.; Pokaż więcej
Źródło:: Nutrients [Nutrients] 2024 Aug 16; Vol. 16 (16). Date of Electronic Publication: 2024 Aug 16.
Typ publikacji:: Journal Article
MeSH Terms:: Alginates*/chemistry
Hippophae*/chemistry
Hydrogels*/chemistry
Carotenoids*/pharmacokinetics
Carotenoids*/administration & dosage
Carotenoids*/analysis
Biological Availability*
Zeaxanthins/chemistry ; Yogurt/analysis ; Sunflower Oil/chemistry ; Humans ; beta Carotene/chemistry ; beta Carotene/pharmacokinetics ; beta Carotene/administration & dosage ; Fruit/chemistry

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