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Tytuł:
Could Sensory Differences Be a Sex-Indifferent Biomarker of Autism? Early Investigation Comparing Tactile Sensitivity Between Autistic Males and Females.
Autorzy:
Asaridou M; Social, Genetic and Developmental Psychiatric Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Wodka EL; Center for Autism and Related Disorders, Kennedy Krieger Institute, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Edden RAE; Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
Mostofsky SH; Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Center for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA.; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Puts NAJ; Department of Forensic and Neurodevelopmental Sciences, Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.
He JL; Department of Forensic and Neurodevelopmental Sciences, Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK. .
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Źródło:
Journal of autism and developmental disorders [J Autism Dev Disord] 2024 Jan; Vol. 54 (1), pp. 239-255. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Autistic Disorder*/diagnosis
Autism Spectrum Disorder*/diagnosis
Child Development Disorders, Pervasive*
Male ; Child ; Humans ; Female ; Sexual Behavior ; Biomarkers
Czasopismo naukowe
Tytuł:
Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression.
Autorzy:
Carey ME; A.J. Drexel Autism Institute, Drexel University, 3020 Market Street, Suite 560, Philadelphia, PA, 19104, United States. .
Rando J; A.J. Drexel Autism Institute, Drexel University, 3020 Market Street, Suite 560, Philadelphia, PA, 19104, United States.
Melnyk S; Arkansas Children's Hospital Research Institute, 13 Childrens Way, Little Rock, AR, 72202, United States.; Department of Pediatrics, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, United States.
James SJ; Department of Pediatrics, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, United States.
Snyder N; Lewis Katz School of Medicine, Temple University, 3500 N Broad St, Philadelphia, PA, 19140, United States.
Salafia C; Department of Pathology, New York Methodist Hospital, 506 6th St, Brooklyn, NY, 11215, United States.
Croen LA; Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, United States.
Fallin MD; A.J. Drexel Autism Institute, Drexel University, 3020 Market Street, Suite 560, Philadelphia, PA, 19104, United States.
Hertz-Picciotto I; Department of Public Health Sciences, University of California, 1 Shields Ave, Davis, CA, 95616, United States.
Volk H; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe St, Baltimore, MD, 21205, United States.
Newschaffer C; College of Health and Human Development, The Pennsylvania State University, 325 Health and Human Development Building, University Park, State College, PA, 16802, United States.
Lyall K; A.J. Drexel Autism Institute, Drexel University, 3020 Market Street, Suite 560, Philadelphia, PA, 19104, United States.
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Źródło:
Journal of autism and developmental disorders [J Autism Dev Disord] 2023 Aug; Vol. 53 (8), pp. 2975-2985. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Autism Spectrum Disorder*/diagnosis
Autism Spectrum Disorder*/complications
Child ; Humans ; Female ; Pregnancy ; Glutathione Disulfide ; Vitamins ; Oxidative Stress ; Biomarkers ; Glutathione/metabolism
Czasopismo naukowe
Tytuł:
Determinants of Leaky Gut and Gut Microbiota Differences in Children With Autism Spectrum Disorder and Their Siblings.
Autorzy:
Yitik Tonkaz G; Child and Adolescent Psychiatry Department, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.
Esin IS; Child and Adolescent Psychiatry Department, Faculty of Medicine, University of Health Sciences, İstanbul, Turkey.
Turan B; Department of Autism, Mental Special Needs and Rare Disease, Turkish Ministry of Health, Ankara, Turkey.
Uslu H; Department of Medical Microbiology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
Dursun OB; Department of Autism, Mental Special Needs and Rare Disease, Turkish Ministry of Health, Ankara, Turkey. .
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Źródło:
Journal of autism and developmental disorders [J Autism Dev Disord] 2023 Jul; Vol. 53 (7), pp. 2703-2716. Date of Electronic Publication: 2022 Apr 20.
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*
Autism Spectrum Disorder*/microbiology
Autistic Disorder*
Humans ; Child ; Siblings ; Biomarkers
Czasopismo naukowe
Tytuł:
Immune biology of NSCLC revealed by single-cell technologies: implications for the development of biomarkers in patients treated with immunotherapy.
Autorzy:
Wlosik J; Team Immunity and Cancer, Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille University UM105, Inserm U1068, 13009, Marseille, France. .; Immunomonitoring Department, Institut Paoli-Calmettes, 13009, Marseille, France. .
Fattori S; Team Immunity and Cancer, Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille University UM105, Inserm U1068, 13009, Marseille, France.; Immunomonitoring Department, Institut Paoli-Calmettes, 13009, Marseille, France.
Rochigneux P; Team Immunity and Cancer, Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille University UM105, Inserm U1068, 13009, Marseille, France.; Immunomonitoring Department, Institut Paoli-Calmettes, 13009, Marseille, France.; Department of Medical Oncology, Inserm U1068, Aix-Marseille University UM105, CNRS UMR7258, Institute Paoli-Calmettes, 13009, Marseille, France.
Goncalves A; Department of Medical Oncology, Inserm U1068, Aix-Marseille University UM105, CNRS UMR7258, Institute Paoli-Calmettes, 13009, Marseille, France.; Team Cell Polarity, Cell Signaling and Cancer, Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille University, Inserm U1068UM 105, 13009, Marseille, France.
Olive D; Team Immunity and Cancer, Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille University UM105, Inserm U1068, 13009, Marseille, France.; Immunomonitoring Department, Institut Paoli-Calmettes, 13009, Marseille, France.
Chretien AS; Team Immunity and Cancer, Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille University UM105, Inserm U1068, 13009, Marseille, France. .; Immunomonitoring Department, Institut Paoli-Calmettes, 13009, Marseille, France. .
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Źródło:
Seminars in immunopathology [Semin Immunopathol] 2023 Jan; Vol. 45 (1), pp. 29-41. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/diagnosis
Carcinoma, Non-Small-Cell Lung*/etiology
Carcinoma, Non-Small-Cell Lung*/therapy
Lung Neoplasms*/therapy
Lung Neoplasms*/drug therapy
Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Biomarkers ; Immunotherapy ; B7-H1 Antigen/therapeutic use ; Biology ; Biomarkers, Tumor/therapeutic use ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
How the variability between computer-assisted analysis procedures evaluating immune markers can influence patients' outcome prediction.
Autorzy:
Lejeune M; Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, Carrer de les Esplanetes, 14, 43500, Tortosa, Spain. .; Universitat Rovira i Virgili (URV), Campus Terres de l'Ebre, Avinguda Remolins nº 13-15, 43500, Tortosa, Spain. .; Institut d'Investigació Sanitària Pere Virgili (IISPV), Hospital Universitari Sant Joan de Reus, Avda. Josep Laporte, 2, Planta 0 - E2 - 43204 Reus; Carrer Dr. Mallafré Guasch, 4, 43007, Tarragona, Spain. .
Plancoulaine B; Normandie University, UNICAEN, INSERM, ANTICIPE, Espl. de La Paix, 14000, Caen, France.; Faculty of Medicine, Vilnius University, M. K. Čiurlionio g. 21, 03101, Vilnius, Lithuania.; Normandie University, UNICAEN, SFR ICORE, CMAbio3, Espl. de la Paix, 14000, Caen, France.
Elie N; Normandie University, UNICAEN, SFR ICORE, CMAbio3, Espl. de la Paix, 14000, Caen, France.
Bosch R; Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, Carrer de les Esplanetes, 14, 43500, Tortosa, Spain.; Institut d'Investigació Sanitària Pere Virgili (IISPV), Hospital Universitari Sant Joan de Reus, Avda. Josep Laporte, 2, Planta 0 - E2 - 43204 Reus; Carrer Dr. Mallafré Guasch, 4, 43007, Tarragona, Spain.
Fontoura L; Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, Carrer de les Esplanetes, 14, 43500, Tortosa, Spain.
de Villasante I; Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, Carrer de les Esplanetes, 14, 43500, Tortosa, Spain.
Korzyńska A; Laboratory of Processing and Analysis of Microscopic Images, Nalęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (IBIB PAN), ul. Ks. Trojdena 4, 02-109, Warsaw, Poland.
Navarro AG; Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, Carrer de les Esplanetes, 14, 43500, Tortosa, Spain.; Universitat Rovira i Virgili (URV), Campus Terres de l'Ebre, Avinguda Remolins nº 13-15, 43500, Tortosa, Spain.
Colón ES; Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, Carrer de les Esplanetes, 14, 43500, Tortosa, Spain.; Institut d'Investigació Sanitària Pere Virgili (IISPV), Hospital Universitari Sant Joan de Reus, Avda. Josep Laporte, 2, Planta 0 - E2 - 43204 Reus; Carrer Dr. Mallafré Guasch, 4, 43007, Tarragona, Spain.
López C; Department of Pathology, Oncological Pathology and Bioinformatics Research Group, Hospital de Tortosa Verge de la Cinta, Carrer de les Esplanetes, 14, 43500, Tortosa, Spain.; Universitat Rovira i Virgili (URV), Campus Terres de l'Ebre, Avinguda Remolins nº 13-15, 43500, Tortosa, Spain.; Institut d'Investigació Sanitària Pere Virgili (IISPV), Hospital Universitari Sant Joan de Reus, Avda. Josep Laporte, 2, Planta 0 - E2 - 43204 Reus; Carrer Dr. Mallafré Guasch, 4, 43007, Tarragona, Spain.
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Źródło:
Histochemistry and cell biology [Histochem Cell Biol] 2021 Nov; Vol. 156 (5), pp. 461-478. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Image Processing, Computer-Assisted*
Biomarkers, Tumor/*analysis
Triple Negative Breast Neoplasms/*diagnostic imaging
Algorithms ; Biomarkers, Tumor/immunology ; Humans ; Immunohistochemistry ; Neoadjuvant Therapy ; Treatment Outcome ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/immunology
Czasopismo naukowe
Tytuł:
Cystatin F acts as a mediator of immune suppression in glioblastoma.
Autorzy:
Senjor E; Department of Biotechnology, Jožef Stefan Institute, Jamova cesta 39, SI-1000, Ljubljana, Slovenia.; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, SI-1000, Ljubljana, Slovenia.
Perišić Nanut M; Department of Biotechnology, Jožef Stefan Institute, Jamova cesta 39, SI-1000, Ljubljana, Slovenia.
Breznik B; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna pot 111, SI-1000, Ljubljana, Slovenia.
Mitrović A; Department of Biotechnology, Jožef Stefan Institute, Jamova cesta 39, SI-1000, Ljubljana, Slovenia.
Mlakar J; Institute of Pathology, Medical Faculty, University of Ljubljana, Korytkova 2, SI-1000, Ljubljana, Slovenia.
Rotter A; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna pot 111, SI-1000, Ljubljana, Slovenia.
Porčnik A; Department of Neurosurgery, University Clinical Centre Ljubljana, SI-1000, Ljubljana, Slovenia.
Lah Turnšek T; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna pot 111, SI-1000, Ljubljana, Slovenia.
Kos J; Department of Biotechnology, Jožef Stefan Institute, Jamova cesta 39, SI-1000, Ljubljana, Slovenia. .; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, SI-1000, Ljubljana, Slovenia. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Oct; Vol. 44 (5), pp. 1051-1063. Date of Electronic Publication: 2021 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*genetics
Brain Neoplasms/*genetics
Cystatins/*genetics
Glioblastoma/*genetics
Killer Cells, Natural/*metabolism
Neoplastic Stem Cells/*metabolism
Biomarkers, Tumor/metabolism ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; CCAAT-Enhancer-Binding Protein-alpha/genetics ; CCAAT-Enhancer-Binding Protein-alpha/metabolism ; Cell Line, Tumor ; Cells, Cultured ; Cystatins/metabolism ; Cytotoxicity, Immunologic/genetics ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Immunohistochemistry ; Microglia/metabolism ; Monocytes/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma.
Autorzy:
Roundhill EA; Children's Cancer Research Group, Leeds Institute of Medical Research, St. James's University Hospital, Leeds, LS9 7TF, UK.
Chicon-Bosch M; Children's Cancer Research Group, Leeds Institute of Medical Research, St. James's University Hospital, Leeds, LS9 7TF, UK.
Jeys L; Royal Orthopaedic Hospital NHS Foundation Trust, Bristol Road South, Northfield, Birmingham, B31 2AP, UK.
Parry M; Royal Orthopaedic Hospital NHS Foundation Trust, Bristol Road South, Northfield, Birmingham, B31 2AP, UK.
Rankin KS; Translational and Clinical Research Institute, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne, NE2 4AD, UK.
Droop A; Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
Burchill SA; Children's Cancer Research Group, Leeds Institute of Medical Research, St. James's University Hospital, Leeds, LS9 7TF, UK. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Oct; Vol. 44 (5), pp. 1065-1085. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing/*genetics
Biomarkers, Tumor/*genetics
Bone Neoplasms/*genetics
Calcium-Binding Proteins/*genetics
Cell Adhesion Molecules, Neuronal/*genetics
Nerve Tissue Proteins/*genetics
Neural Cell Adhesion Molecules/*genetics
Sarcoma, Ewing/*genetics
Adaptor Proteins, Signal Transducing/metabolism ; Antineoplastic Agents/pharmacology ; Biomarkers, Tumor/metabolism ; Bone Neoplasms/metabolism ; Calcium-Binding Proteins/metabolism ; Cell Adhesion Molecules, Neuronal/metabolism ; Cell Line, Tumor ; Child ; Doxorubicin/pharmacology ; Gene Expression Regulation, Neoplastic ; Humans ; Kaplan-Meier Estimate ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/metabolism ; Nerve Tissue Proteins/metabolism ; Neural Cell Adhesion Molecules/metabolism ; Prognosis ; Sarcoma, Ewing/metabolism ; Sequence Analysis, RNA/methods ; Transcriptome/genetics ; Tumor Cells, Cultured ; Vincristine/pharmacology
Czasopismo naukowe
Tytuł:
Loss of ARID1A expression promotes lung adenocarcinoma metastasis and predicts a poor prognosis.
Autorzy:
Sun D; Precision Medicine Center of Oncology, The Affiliated Hospital of Qingdao University, 59 Haier Road, Shandong, 266000, Qingdao, China.
Zhu Y; Department of Medical Oncology, The Municipal Hospital of Qingdao, 266000, Qingdao, China.
Zhao H; Department of Pathology, The Affiliated Hospital of Qingdao University, 266000, Qingdao, China.
Bian T; Breast Disease Center, The Affiliated Hospital of Qingdao University, Qingdao University, 266100, Qingdao, China.
Li T; Precision Medicine Center of Oncology, The Affiliated Hospital of Qingdao University, 59 Haier Road, Shandong, 266000, Qingdao, China.
Liu K; Precision Medicine Center of Oncology, The Affiliated Hospital of Qingdao University, 59 Haier Road, Shandong, 266000, Qingdao, China.
Feng L; Department of General Surgery, Qingdao Eighth People's Hospital, 266041, Qingdao, China.
Li H; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China. .
Hou H; Precision Medicine Center of Oncology, The Affiliated Hospital of Qingdao University, 59 Haier Road, Shandong, 266000, Qingdao, China. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Oct; Vol. 44 (5), pp. 1019-1034. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Mutation*
Adenocarcinoma of Lung/*genetics
Biomarkers, Tumor/*genetics
DNA-Binding Proteins/*genetics
Lung Neoplasms/*genetics
Transcription Factors/*genetics
A549 Cells ; Adenocarcinoma of Lung/metabolism ; Adenocarcinoma of Lung/pathology ; Animals ; Biomarkers, Tumor/metabolism ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; DNA-Binding Proteins/metabolism ; Female ; Humans ; Immunohistochemistry ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Mice, Inbred BALB C ; Mice, Nude ; Mice, SCID ; Neoplasm Metastasis ; Nomograms ; Prognosis ; Transcription Factors/metabolism ; Transplantation, Heterologous ; Mice
Czasopismo naukowe
Tytuł:
Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia.
Autorzy:
Lipreri da Silva JC; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Coelho-Silva JL; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Lima K; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Vicari HP; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Lazarini M; Department of Pharmaceutical Sciences, Federal University of São Paulo, Diadema, Brazil.
Costa-Lotufo LV; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Traina F; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Machado-Neto JA; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Oct; Vol. 44 (5), pp. 1105-1117. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Leukemic*
Biomarkers, Tumor/*genetics
Cytoskeletal Proteins/*genetics
Cytoskeleton/*metabolism
Genes, Regulator/*genetics
Leukemia, Myeloid/*genetics
Acute Disease ; Adamantane/analogs & derivatives ; Adamantane/pharmacology ; Adult ; Biomarkers, Tumor/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Cytoskeletal Proteins/antagonists & inhibitors ; Cytoskeletal Proteins/metabolism ; Disease-Free Survival ; Female ; HL-60 Cells ; Humans ; K562 Cells ; Leukemia, Myeloid/diagnosis ; Leukemia, Myeloid/metabolism ; Male ; Phenols/pharmacology ; Prognosis ; Quinolines/pharmacology ; Quinolones/pharmacology ; THP-1 Cells ; U937 Cells
Czasopismo naukowe
Tytuł:
An integrative approach based on GC-qMS and NMR metabolomics data as a comprehensive strategy to search potential breast cancer biomarkers.
Autorzy:
Silva CL; CQM - Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal.
Perestrelo R; CQM - Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal.
Capelinha F; Serviço de Anatomia Patológica, Hospital Dr. Nélio Mendonça, Avenida Luís de Camões, nº 57, 9004-514, Funchal, Portugal.
Tomás H; CQM - Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal.; Departamento de Química, Faculdade de Ciências Exactas e Engenharia da Universidade da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal.
Câmara JS; CQM - Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal. .; Departamento de Química, Faculdade de Ciências Exactas e Engenharia da Universidade da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal. .
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Źródło:
Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2021 Aug 13; Vol. 17 (8), pp. 72. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/metabolism
Biomarkers, Tumor*/urine
Breast Neoplasms*/chemistry
Breast Neoplasms*/metabolism
Breast Neoplasms*/urine
Metabolomics*/methods
Adult ; Aged ; Aged, 80 and over ; Female ; Gas Chromatography-Mass Spectrometry/methods ; Humans ; Magnetic Resonance Spectroscopy/methods ; Middle Aged ; Urine/chemistry
Czasopismo naukowe
Tytuł:
Functional estrogen receptor signaling pathway activity in high-grade serous ovarian carcinoma as compared to estrogen receptor protein expression by immunohistochemistry.
Autorzy:
van der Ploeg P; Department of Obstetrics and Gynecology, Catharina Hospital, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands. .; GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands. .
van Lieshout LAM; Department of Obstetrics and Gynecology, Catharina Hospital, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands.; Radboud Institute for Health Sciences, Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
van de Stolpe A; Molecular Pathway Dx, Philips, Eindhoven, The Netherlands.
Bosch SL; Laboratory for Pathology and Medical Microbiology (Stichting PAMM), Eindhoven, The Netherlands.
Lentjes-Beer MHFM; Laboratory for Pathology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
Bekkers RLM; Department of Obstetrics and Gynecology, Catharina Hospital, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Piek JMJ; Department of Obstetrics and Gynecology, Catharina Hospital, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Aug; Vol. 44 (4), pp. 951-957. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Biomarkers, Tumor/*genetics
Cystadenocarcinoma, Serous/*genetics
Estrogen Receptor alpha/*genetics
Ovarian Neoplasms/*genetics
Signal Transduction/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Cystadenocarcinoma, Serous/drug therapy ; Cystadenocarcinoma, Serous/metabolism ; Estrogen Receptor alpha/biosynthesis ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; Neoplasm Grading ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Retrospective Studies ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł:
TIMEAS, a promising method for the stratification of testicular germ cell tumor patients with distinct immune microenvironment, clinical outcome and sensitivity to frontline therapies.
Autorzy:
Meng J; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China.
Gao J; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China.
Li X; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China.
Gao R; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China.
Lu X; State Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, 211198, Nanjing, China.
Zhou J; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China.
Yan F; State Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, 211198, Nanjing, China.
Wang H; Cancer Center, Faculty of Health Sciences, Center for Precision Medicine Research and Training, University of Macau, SAR, Macau, People's Republic of China.; Center for Cancer Research, Clinical Research/NCI/NIH, Bethesda, MD, 20892, USA.
Liu Y; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China.
Hao Z; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China. .
Zhang X; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China. .
Liang C; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Institute of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, 218th Jixi Road, 230022, Hefei, People's Republic of China. liang_.
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2023 Jun; Vol. 46 (3), pp. 745-759. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Testicular Neoplasms*/drug therapy
Neoplasms, Germ Cell and Embryonal*
Male ; Humans ; Biomarkers, Tumor/genetics ; Immunotherapy/methods ; Tumor Microenvironment ; Carrier Proteins ; Microfilament Proteins/therapeutic use
SCR Disease Name:
Testicular Germ Cell Tumor
Czasopismo naukowe
Tytuł:
TRIM44 regulates tumor immunity in gastric cancer through LOXL2-dependent extracellular matrix remodeling.
Autorzy:
Zhang X; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, 250012, JiNan, China.
Wu X; Department of General Surgery, Linyi People's Hospital, 105 Plaza Street, Linyi County, China.
Sun Y; Department of Blood quality Control, Yantai central blood station, 10 Haiyun Road, Yantai, China.
Chu Y; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, 250012, JiNan, China.
Liu F; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, 250012, JiNan, China.
Chen C; Department of General Surgery, Qilu Hospital of Shandong University, 107 West Wenhua Road, 250012, JiNan, China. cc_.
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2023 Apr; Vol. 46 (2), pp. 423-435. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Matrix*/metabolism
Stomach Neoplasms*/genetics
Stomach Neoplasms*/immunology
Tumor Microenvironment*/immunology
Humans ; Amino Acid Oxidoreductases/genetics ; Amino Acid Oxidoreductases/metabolism ; Biomarkers ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Intracellular Signaling Peptides and Proteins/metabolism ; Tripartite Motif Proteins/metabolism
Czasopismo naukowe
Tytuł:
Salivary metabolomics for the diagnosis of periodontal diseases: a systematic review with methodological quality assessment.
Autorzy:
Baima G; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy. .
Iaderosa G; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.
Citterio F; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.
Grossi S; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.
Romano F; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.
Berta GN; Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Buduneli N; Department of Periodontology, School of Dentistry, Ege University, İzmir, Turkey.
Aimetti M; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.
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Źródło:
Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2021 Jan 01; Vol. 17 (1), pp. 1. Date of Electronic Publication: 2021 Jan 01.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Biomarkers*
Metabolomics/*methods
Periodontal Diseases/*diagnosis
Periodontal Diseases/*metabolism
Saliva/*metabolism
Humans ; Liquid Biopsy/methods ; Liquid Biopsy/standards ; Metabolic Networks and Pathways ; Metabolomics/standards ; Oxidative Stress ; Periodontal Diseases/etiology ; Reference Values
Czasopismo naukowe
Tytuł:
AKR1C3 is a biomarker and druggable target for oropharyngeal tumors.
Autorzy:
Peraldo-Neia C; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy.
Ostano P; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy.
Mello-Grand M; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy.
Guana F; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy.
Gregnanin I; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy.
Boschi D; Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
Oliaro-Bosso S; Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
Pippione AC; Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
Carenzo A; Integrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy.
De Cecco L; Integrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy.
Cavalieri S; Head and Neck Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Micali A; Integrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy.
Perrone F; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Averono G; Otorhinolaryngology Unit, Ospedale degli Infermi, via dei Ponderanesi 1, Ponderano, Biella, Italy.
Bagnasacco P; Otorhinolaryngology Unit, Ospedale degli Infermi, via dei Ponderanesi 1, Ponderano, Biella, Italy.
Dosdegani R; Otorhinolaryngology Unit, Ospedale Sant'Andrea, Vercelli, Italy.
Masini L; Department of Translational Medicine, UPO School of Medicine, Radiotherapy Unit, Novara, Italy.
Krengli M; Department of Translational Medicine, UPO School of Medicine, Radiotherapy Unit, Novara, Italy.
Aluffi-Valletti P; Department of Health Sciences, UPO School of Medicine, Otorhinolaryngology Unit, Novara, Italy.
Valente G; Department of Translational Medicine, UPO School of Medicine, Radiotherapy Unit, Novara, Italy.
Chiorino G; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Apr; Vol. 44 (2), pp. 357-372. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Aldo-Keto Reductase Family 1 Member C3/*metabolism
Biomarkers, Tumor/*metabolism
Oropharyngeal Neoplasms/*metabolism
Aged ; Aged, 80 and over ; Aldo-Keto Reductase Family 1 Member C3/genetics ; Biomarkers, Tumor/genetics ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/virology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Survival/drug effects ; Cisplatin/pharmacology ; Down-Regulation/genetics ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Gene Regulatory Networks ; Humans ; Male ; Middle Aged ; Oropharyngeal Neoplasms/genetics ; Oropharyngeal Neoplasms/pathology ; Oropharyngeal Neoplasms/virology ; Papillomavirus Infections/complications ; Prognosis ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł:
CREPT serves as a biomarker of poor survival in pancreatic ductal adenocarcinoma.
Autorzy:
Yang G; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Wang Y; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Xiao J; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Zhao F; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Qiu J; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Liu Y; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Chen G; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Cao Z; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
You L; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China.
Zheng L; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Zhang T; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China. .; Clinical Immunology Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. .
Zhao Y; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing Street, Beijing, 100730, China. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Apr; Vol. 44 (2), pp. 345-355. Date of Electronic Publication: 2020 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma/*metabolism
Biomarkers, Tumor/*metabolism
Carcinoma, Pancreatic Ductal/*metabolism
Cell Cycle Proteins/*metabolism
Neoplasm Proteins/*metabolism
Pancreatic Neoplasms/*metabolism
Adenocarcinoma/genetics ; Animals ; Biomarkers, Tumor/genetics ; Carcinoma, Pancreatic Ductal/genetics ; Cell Cycle Proteins/genetics ; Cell Line, Tumor ; Disease-Free Survival ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Multivariate Analysis ; Neoplasm Proteins/genetics ; Pancreatic Neoplasms/genetics ; Prognosis ; Survival Analysis ; Up-Regulation/genetics ; Mice
Czasopismo naukowe
Tytuł:
Discrepancies in metabolomic biomarker identification from patient-derived lung cancer revealed by combined variation in data pre-treatment and imputation methods.
Autorzy:
Miller HA; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA.
Emam R; Department of Bioengineering, University of Louisville, Louisville, KY, USA.
Lynch CM; Department of Computer Engineering and Computer Science, University of Louisville, Louisville, USA.
Bockhorst S; Department of Medicine, University of Louisville, Louisville, USA.
Frieboes HB; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA. .; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA. .; Center for Predictive Medicine, University of Louisville, Louisville, KY, USA. .; Department of Bioengineering, University of Louisville, Lutz Hall 419, Louisville, KY, 40292, USA. .
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Źródło:
Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2021 Mar 27; Vol. 17 (4), pp. 37. Date of Electronic Publication: 2021 Mar 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Biomarkers*
Lung Neoplasms/*metabolism
Metabolomics/*methods
Data Analysis ; Humans ; Lung Neoplasms/therapy ; Principal Component Analysis
Czasopismo naukowe
Tytuł:
Cardiovascular Biomarkers' Inherent Timescales in Mental Workload Assessment During Simulated Air Traffic Control Tasks.
Autorzy:
Radüntz T; Unit Mental Health and Cognitive Capacity, Federal Institute for Occupational Safety and Health, Nöldnerstr. 40-42, 10317, Berlin, Germany. .
Mühlhausen T; Institute of Flight Guidance, German Aerospace Center, Brunswick, Germany.
Freyer M; Unit Mental Health and Cognitive Capacity, Federal Institute for Occupational Safety and Health, Nöldnerstr. 40-42, 10317, Berlin, Germany.
Fürstenau N; Institute of Flight Guidance, German Aerospace Center, Brunswick, Germany.
Meffert B; Department of Computer Science, Humboldt-Universität zu Berlin, Berlin, Germany.
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Źródło:
Applied psychophysiology and biofeedback [Appl Psychophysiol Biofeedback] 2021 Mar; Vol. 46 (1), pp. 43-59. Date of Electronic Publication: 2020 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers*
Ergonomics*
Aviation/*instrumentation
Heart Rate/*physiology
Workload/*psychology
Adult ; Computer Simulation ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł:
Integrating genetics with newborn metabolomics in infantile hypertrophic pyloric stenosis.
Autorzy:
Fadista J; Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark. .; Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden. .; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. .
Skotte L; Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark.
Courraud J; Danish Center for Neonatal Screening, Clinical Mass Spectrometry, Statens Serum Institut, Copenhagen, Denmark.
Geller F; Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark.
Gørtz S; Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark.
Wohlfahrt J; Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark.
Melbye M; Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Cohen AS; Danish Center for Neonatal Screening, Clinical Mass Spectrometry, Statens Serum Institut, Copenhagen, Denmark.
Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark. .
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Źródło:
Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2021 Jan 08; Vol. 17 (1), pp. 7. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers*
Genetic Predisposition to Disease*
Metabolome*
Metabolomics*/methods
Pyloric Stenosis, Hypertrophic/*genetics
Pyloric Stenosis, Hypertrophic/*metabolism
Case-Control Studies ; Chromatography, Liquid ; Computational Biology ; Denmark ; Feeding Behavior ; Female ; Genetic Association Studies ; Genetic Variation ; Humans ; Infant, Newborn ; Male ; Mass Spectrometry ; Polymorphism, Single Nucleotide ; Pyloric Stenosis, Hypertrophic/diagnosis
Czasopismo naukowe
Tytuł:
Distinctive metabolic profiles between Cystic Fibrosis mutational subclasses and lung function.
Autorzy:
Masood A; Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, PO. Box 2925 (98), Riyadh, 11461, Saudi Arabia.
Jacob M; Metabolomics Section, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Centre (KFSHRC), Zahrawi Street, Al Maather, PO. Box 3354, Riyadh, 11211, Saudi Arabia.
Gu X; Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2R3, Canada.
Abdel Jabar M; Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2R3, Canada.
Benabdelkamel H; Proteomics Resource Unit, Obesity Research Center, College of Medicine, King Saud University, PO. Box 2925 (98), Riyadh, 11461, Saudi Arabia.
Nizami I; Lung Transplant Section, Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Zahrawi Street, Al Maather, Riyadh, 11211, Saudi Arabia.
Li L; Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2R3, Canada.
Dasouki M; Metabolomics Section, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Centre (KFSHRC), Zahrawi Street, Al Maather, PO. Box 3354, Riyadh, 11211, Saudi Arabia.
Abdel Rahman AM; Metabolomics Section, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Centre (KFSHRC), Zahrawi Street, Al Maather, PO. Box 3354, Riyadh, 11211, Saudi Arabia. .; Department of Biochemistry and Molecular Medicine, College of Medicine, Al Faisal University, Riyadh, Saudi Arabia. .; Department of Chemistry, Memorial University of Newfoundland, St. John's, NL, A1B 3X7, Canada. .
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Źródło:
Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2021 Jan 04; Vol. 17 (1), pp. 4. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers*
Metabolome*
Metabolomics*/methods
Mutation*
Cystic Fibrosis/*genetics
Cystic Fibrosis/*metabolism
Case-Control Studies ; Chromatography, Liquid ; Cystic Fibrosis/diagnosis ; Humans ; Mass Spectrometry ; Respiratory Function Tests ; Severity of Illness Index
Czasopismo naukowe

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