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Wyszukujesz frazę ""Biomarkers, Tumor metabolism"" wg kryterium: Temat


Tytuł:
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care
Autorzy:
Clemens Gutmann
Kaloyan Takov
Sean A. Burnap
Bhawana Singh
Hashim Ali
Konstantinos Theofilatos
Ella Reed
Maria Hasman
Adam Nabeebaccus
Matthew Fish
Mark JW. McPhail
Kevin O’Gallagher
Lukas E. Schmidt
Christian Cassel
Marieke Rienks
Xiaoke Yin
Georg Auzinger
Salvatore Napoli
Salma F. Mujib
Francesca Trovato
Barnaby Sanderson
Blair Merrick
Umar Niazi
Mansoor Saqi
Konstantina Dimitrakopoulou
Rafael Fernández-Leiro
Silke Braun
Romy Kronstein-Wiedemann
Katie J. Doores
Jonathan D. Edgeworth
Ajay M. Shah
Stefan R. Bornstein
Torsten Tonn
Adrian C. Hayday
Mauro Giacca
Manu Shankar-Hari
Manuel Mayr
Pokaż więcej
Temat:
General Physics and Astronomy
General Biochemistry, Genetics and Molecular Biology
General Chemistry
Article
Mass spectrometry
SARS-CoV-2
Prognostic markers
Adult
Animals
Antibodies, Neutralizing/immunology
Antigens, Neoplasm/metabolism
Biomarkers, Tumor/metabolism
C-Reactive Protein/metabolism
COVID-19/metabolism
Critical Care/statistics & numerical data
Female
HEK293 Cells
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Proteomics/methods
RNA, Viral/blood
SARS-CoV-2/genetics
Serum Amyloid P-Component/metabolism
Spike Glycoprotein, Coronavirus/immunology
Viral Load/immunology
Science
Źródło:
Nature Communications
Gutmann, C, Takov, K, Burnap, S A, Singh, B, Ali, H, Theofilatos, K, Reed, E, Hasman, M, Nabeebaccus, A, Fish, M, McPhail, M J, O'Gallagher, K, Schmidt, L E, Cassel, C, Rienks, M, Yin, X, Auzinger, G, Napoli, S, Mujib, S F, Trovato, F, Sanderson, B, Merrick, B, Niazi, U, Saqi, M, Dimitrakopoulou, K, Fernández-Leiro, R, Braun, S, Kronstein-Wiedemann, R, Doores, K J, Edgeworth, J D, Shah, A M, Bornstein, S R, Tonn, T, Hayday, A C, Giacca, M, Shankar-Hari, M & Mayr, M 2021, ' SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care ', Nature Communications, vol. 12, no. 1, 3406, pp. 3406 . https://doi.org/10.1038/s41467-021-23494-1
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b54981bd87b0451c4c66e6cc9dea4d
http://www.nature.com/articles/s41467-021-23494-1.pdf
Tytuł:
Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial
Autorzy:
Skriver, Signe Korsgaard
Jensen, Maj-Britt
Knoop, Ann Soegaard
Ejlertsen, Bent
Laenkholm, Anne-Vibeke
Pokaż więcej
Temat:
Breast neoplasms
Neoadjuvant
Endocrine therapy
Letrozole
TILs
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
Research Article
Breast cancer
medicine.disease
medicine
Phases of clinical research
Biomarker (medicine)
Oncology
medicine.medical_specialty
Chemotherapy
medicine.medical_treatment
business.industry
business
Surgical oncology
Internal medicine
medicine.drug
Immunotherapy
Aged
Aged, 80 and over
Antineoplastic Agents/therapeutic use
Biomarkers, Tumor/metabolism
Breast Neoplasms/drug therapy
Carcinoma, Ductal, Breast/drug therapy
Carcinoma, Lobular/drug therapy
Female
Follow-Up Studies
Humans
Letrozole/therapeutic use
Lymphocytes, Tumor-Infiltrating/drug effects
Middle Aged
Neoadjuvant Therapy
Prognosis
Receptor, ErbB-2/metabolism
Receptors, Estrogen/metabolism
Receptors, Progesterone/metabolism
chemical and pharmacologic phenomena
Źródło:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-8 (2020)
Breast Cancer Research : BCR
Skriver, S K, Jensen, M-B, Knoop, A S, Ejlertsen, B & Laenkholm, A-V 2020, ' Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer : analysis from a nationwide phase II DBCG trial ', Breast cancer research : BCR, vol. 22, no. 1, 46 . https://doi.org/10.1186/s13058-020-01285-8
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82c45d0a7db5cf84f808db9f950744d
http://link.springer.com/article/10.1186/s13058-020-01285-8
Tytuł:
Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas
Autorzy:
Aaberg-Jessen, Charlotte
Sørensen, Mia Dahl
Matos, Ana L.S.A.
Moreira, José M.
Brünner, Nils
Møldrup Knudsen, Arnon
Kristensen, Bjarne W.
Pokaż więcej
Temat:
TIMP
CD63
LAMP-3
Glioblastoma
Glioma
Astrocytoma
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
Cancer Research
Genetics
Oncology
medicine.disease
medicine
Cell
medicine.anatomical_structure
Immunofluorescence
medicine.diagnostic_test
SOX2
Biology
Proximity ligation assay
Cancer research
Stem cell marker
Biomarker
Extracellular matrix
Microglia
Prognosis
Immunoprecipitation
Follow-Up Studies
Humans
Middle Aged
Child, Preschool
Male
Young Adult
Adult
Female
Child
Tetraspanin 30/metabolism
Glioblastoma/metabolism
Tissue Inhibitor of Metalloproteinase-1/metabolism
Neoplastic Stem Cells/metabolism
Survival Rate
Cell Membrane/metabolism
Adolescent
Aged
Biomarkers, Tumor/metabolism
Cohort Studies
Research Article
Journal Article
Research Support, Non-U.S. Gov't
Źródło:
BMC Cancer, Vol 18, Iss 1, Pp 1-16 (2018)
Aaberg-Jessen, C, Sørensen, M D, Matos, A L S A, Moreira, J M, Brünner, N, Knudsen, A & Kristensen, B W 2018, ' Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas ', BMC Cancer, vol. 18, 270 . https://doi.org/10.1186/s12885-018-4179-y
BMC Cancer
Aaberg-Jessen, C, Sørensen, M D, Matos, A L S A, Moreira, J M, Brünner, N, Møldrup Knudsen, A & Kristensen, B W 2018, ' Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas ', BMC Cancer, vol. 18, 270 . https://doi.org/10.1186/s12885-018-4179-y
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b911ccc56fd18c192a4a811a96ada3f
http://link.springer.com/article/10.1186/s12885-018-4179-y
Tytuł:
Physiologic distribution of PSMA-ligand in salivary glands and seromucous glands of the head and neck on PET/CT
Autorzy:
Klein Nulent, T.J.W.
Valstar, M.H.
de Keizer, B.
Willems, S.M.
Smit, L.A.
Al-Mamgani, A.
Smeele, L.E.
van Es, R.J.J.
de Bree, Remco
Vogel, W.V.
Pokaż więcej
Temat:
Surgery
Oral Surgery
Pathology and Forensic Medicine
Dentistry (miscellaneous)
Radiology Nuclear Medicine and imaging
Aged
80 and over
Antigens
Surface/metabolism
Biomarkers
Tumor/metabolism
Exocrine Glands/metabolism
Glutamate Carboxypeptidase II/metabolism
Head/diagnostic imaging
Humans
Lacrimal Apparatus/metabolism
Male
Middle Aged
Neck/diagnostic imaging
Neoplasm Staging
Positron Emission Tomography Computed Tomography
Prostatic Neoplasms/diagnostic imaging
Salivary Glands/metabolism
Whole Body Imaging
PET-CT
Positron emission tomography
medicine.diagnostic_test
medicine
Soft palate
medicine.anatomical_structure
Lacrimal apparatus
Nuclear medicine
business.industry
business
Prostate cancer
medicine.disease
Exocrine gland
Salivary gland
Head and neck cancer
Aged, 80 and over
Antigens, Surface/metabolism
Biomarkers, Tumor/metabolism
urologic and male genital diseases
Źródło:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 125(5), 478-486. Elsevier
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 125(5), 478. Elsevier USA
Oral surgery, oral medicine, oral pathology and oral radiology, 125(5), 478-486. Elsevier USA
Oral surgery, oral medicine, oral pathology and oral radiology, 125(5), 478-486
Opis pliku:
image/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462c752c243d6630e188d47d02df34d3
Tytuł:
Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer
Autorzy:
Lan, Qiang
Peyvandi, Sanam
Duffey, Nathalie
Huang, Yu-Ting
Barras, David
Held, Werner
Richard, François
Delorenzi, Mauro
Sotiriou, Christos
Desmedt, Christine
Lorusso, Girieca
Rüegg, Curzio
Pokaż więcej
Temat:
Cancer Research
Genetics
Molecular Biology
Cancer cell
Adjuvant
medicine.medical_treatment
medicine
Doxorubicin
medicine.drug
Tumor-infiltrating lymphocytes
Metastasis
medicine.disease
Chemotherapy
Breast cancer
Biology
Epirubicin
Cancer research
Cancérologie
Sciences bio-médicales et agricoles
Médecine pathologie humaine
Animals
Antineoplastic Combined Chemotherapy Protocols -- pharmacology
Biomarkers, Tumor -- metabolism
Breast Neoplasms -- drug therapy -- metabolism
Cell Line, Tumor
Chemotherapy, Adjuvant -- methods
Doxorubicin -- pharmacology
Epirubicin -- pharmacology
Female
Humans
Interferon Regulatory Factor-7 -- metabolism
Interferon Type I -- metabolism
Interferon-beta -- metabolism
Methotrexate -- pharmacology
Mice
Mice, Inbred BALB C
Mice, Inbred NOD
Mice, Nude
Mice, SCID
Neoadjuvant Therapy -- methods
Neoplasm Recurrence, Local -- metabolism
Receptor, ErbB-2 -- metabolism
Article
Immunology
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Oncology
Cell Biology
Genetics & Heredity
TUMOR-INFILTRATING LYMPHOCYTES
IMMUNE-MEDIATED DORMANCY
CELLS
METASTASIS
MECHANISMS
EXPRESSION
RESISTANCE
PATHWAY
SITE
Antineoplastic Combined Chemotherapy Protocols/pharmacology
Biomarkers, Tumor/metabolism
Breast Neoplasms/drug therapy
Breast Neoplasms/metabolism
Chemotherapy, Adjuvant/methods
Doxorubicin/pharmacology
Epirubicin/pharmacology
Interferon Regulatory Factor-7/metabolism
Interferon Type I/metabolism
Interferon-beta/metabolism
Methotrexate/pharmacology
Neoadjuvant Therapy/methods
Neoplasm Recurrence, Local/metabolism
Receptor, ErbB-2/metabolism
3122 Cancers
Źródło:
Oncogene
Oncogene, vol. 38, no. 15, pp. 2814-2829
Opis pliku:
1 full-text file(s): application/pdf; Print-Electronic; application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446e867fdca9c49aae8adeb950afd7f3
Tytuł:
Aberrant up-regulation of iNOS/NO system is correlated with an increased abundance of Foxp3+ cells and reduced effector/memory cell markers expression during colorectal cancer: immunomodulatory effects of cetuximab combined with chemotherapy
Autorzy:
Chafia Touil-Boukoffa
Sonia Ait-Younes
Olivier Morales
Oussama Medjeber
Hassen Mahfouf
Hayet Rafa
Sabah Hetit
Nadira Delhem
Said Belhadef
Yvan de Launoit
Mourad Belkhelfa
Hayat Ait-Kaci
Sarra Benkhelifa
Pokaż więcej
Temat:
Host immune responses
Immunomodulation
iNOS/NO system
Cetuximab and chemotherapy
Colorectal Cancer
MESH: Adult
MESH: Aged
MESH: Forkhead Transcription Factors/metabolism
MESH: Humans
MESH: Immunologic Factors/metabolism
MESH: Male
MESH: Middle Aged
MESH: Nitric Oxide/metabolism
MESH: Nitric Oxide Synthase Type II/metabolism
MESH: T-Lymphocytes, Regulatory/drug effects
MESH: Up-Regulation/drug effects
MESH: Up-Regulation/physiology
MESH: Aged, 80 and over
MESH: Biomarkers, Tumor/metabolism
MESH: Cetuximab/therapeutic use
MESH: Colorectal Neoplasms/drug therapy
MESH: Colorectal Neoplasms/metabolism
MESH: Down-Regulation/drug effects
MESH: Down-Regulation/physiology
MESH: Female
[SDV]Life Sciences [q-bio]
[SDV.CAN]Life Sciences [q-bio]/Cancer
Pharmacology (medical)
Pharmacology
Immunology
Chemotherapy
medicine.medical_treatment
medicine
FOXP3
Immune system
Memory T cell
medicine.anatomical_structure
Colorectal cancer
medicine.disease
Cancer research
Biomarker (medicine)
Inflammation
medicine.symptom
Cetuximab
medicine.drug
business.industry
business
Źródło:
Inflammopharmacology
Inflammopharmacology, Springer Verlag, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c14e2c54400f0d81e84b20996df275
https://hal.archives-ouvertes.fr/hal-02391591
Tytuł:
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer
Autorzy:
Wirbel, Jakob
Pyl, Paul Theodor
Kartal, Ece
Zych, Konrad
Kashani, Alireza
Milanese, Alessio
Fleck, Jonas S.
Voigt, Anita Y.
Palleja, Albert
Ponnudurai, Ruby
Sunagawa, Shinichi
Coelho, Luis Pedro
Schrotz-King, Petra
Vogtmann, Emily
Habermann, Nina
Niméus, Emma
Thomas, Andrew M.
Manghi, Paolo
Gandini, Sara
Serrano, Davide
Mizutani, Sayaka
Shiroma, Hirotsugu
Shiba, Satoshi
Shibata, Tatsuhiro
Yachida, Shinichi
Yamada, Takuji
Waldron, Levi
Naccarati, Alessio
Segata, Nicola
Sinha, Rashmi
Ulrich, Cornelia M.
Brenner, Hermann
Arumugam, Manimozhiyan
Bork, Peer
Zeller, Georg
Pokaż więcej
Temat:
Article
Adenoma/genetics
Aged
Biomarkers, Tumor/metabolism
Cohort Studies
Colorectal Neoplasms/genetics
Databases, Genetic
Feces/microbiology
Female
Gastrointestinal Microbiome/genetics
Humans
Male
Metagenome
Middle Aged
Models, Biological
Reproducibility of Results
Species Specificity
General Biochemistry, Genetics and Molecular Biology
General Medicine
Biology
Computational biology
Colorectal cancer
medicine.disease
medicine
Medical genetics
medicine.medical_specialty
Metagenomics
Genetic association
False discovery rate
Microbiome
Disease
Gene
Źródło:
Nat Med
Wirbel, J, Pyl, P T, Kartal, E, Zych, K, Kashani, A, Milanese, A, Fleck, J S, Voigt, A Y, Palleja, A, Ponnudurai, R, Sunagawa, S, Coelho, L P, Schrotz-King, P, Vogtmann, E, Habermann, N, Niméus, E, Thomas, A M, Manghi, P, Gandini, S, Serrano, D, Mizutani, S, Shiroma, H, Shiba, S, Shibata, T, Yachida, S, Yamada, T, Waldron, L, Naccarati, A, Segata, N, Sinha, R, Ulrich, C M, Brenner, H, Arumugam, M, Bork, P & Zeller, G 2019, ' Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer ', Nature Medicine, vol. 25, no. 4, pp. 679-689 . https://doi.org/10.1038/s41591-019-0406-6
Nature Medicine
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10216c8f22a1e3d8cfcb2804e67a9cc
https://europepmc.org/articles/PMC7984229/
Tytuł:
The CLEC12A receptor marks human basophils: Potential implications for minimal residual disease detection in acute myeloid leukemia
Autorzy:
Anne Stidsholt Roug
Trine Lindhardt Plesner
Gordon D. Brown
Marie Toft-Petersen
Line Nederby
Lene Hyldahl Ebbesen
Pokaż więcej
Temat:
Cell Biology
Histology
Pathology and Forensic Medicine
Transmembrane protein
Immunology
Leukemia
medicine.disease
medicine
Internal medicine
medicine.medical_specialty
Biology
Minimal residual disease
Myeloid
medicine.anatomical_structure
Immunophenotyping
Myeloid leukemia
Receptor
Hematology
basophils
CD371
CLEC12A
hMICL
immunophenotyping
Humans
Flow Cytometry/methods
Leukemia, Myeloid, Acute/diagnosis
Dendritic Cells/metabolism
Lectins, C-Type/metabolism
Receptors, Mitogen/metabolism
Basophils/metabolism
Neoplasm, Residual/diagnosis
Biomarkers, Tumor/metabolism
Źródło:
Toft-Petersen, M, Stidsholt Roug, A, Plesner, T, Ebbesen, L, Brown, G D & Nederby, L 2018, ' The CLEC12A receptor marks human basophils: Potential implications for minimal residual disease detection in acute myeloid leukemia ', Cytometry. Part B: Clinical Cytometry, vol. 94, no. 3, pp. 520-526 . https://doi.org/10.1002/cyto.b.21540
Toft-Petersen, M, Stidsholt Roug, A, Plesner, T, Ebbesen, L, Brown, G D & Nederby, L 2018, ' The CLEC12A receptor marks human basophils : Potential implications for minimal residual disease detection in acute myeloid leukemia ', Cytometry. Part B: Clinical Cytometry, vol. 94, no. 3, pp. 520-526 . https://doi.org/10.1002/cyto.b.21540
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b72382b12ad375fb73fd791ccec1fa2
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcyto.b.21540
Tytuł:
Elucidation of Altered Pathways in Tumor-Initiating Cells of Triple-Negative Breast Cancer: A Useful Cell Model System for Drug Screening
Autorzy:
Richa Batra
Sidse Ehmsen
Henrik J. Ditzel
Mikkel Green Terp
Anne Geske Lindhard Christensen
Rikke Leth-Larsen
Nicolas Alcaraz
Julie B. Noer
José M.A. Moreira
Martin R. Larsen
Jan Baumbach
Pokaż więcej
Temat:
Cell Biology
Developmental Biology
Molecular Medicine
Cell biology
Cancer stem cell
Cell growth
Stem cell
Carcinogenesis
medicine.disease_cause
medicine
Cancer cell
Wnt signaling pathway
Biology
Suicide gene
FADD
biology.protein
Journal Article
NF-κB
Targeted treatment
Cancer stem cells
Mammospheres
Apoptosis
Triple-negative breast cancer
Cell Proliferation
Antigens, CD/metabolism
Humans
Neoplastic Stem Cells/pathology
Protein Interaction Maps
Triple Negative Breast Neoplasms/drug therapy
Cell Shape
Mass Spectrometry
Epithelial-Mesenchymal Transition
Female
Drug Evaluation, Preclinical
Wnt Signaling Pathway
Spheroids, Cellular/pathology
Reproducibility of Results
Signal Transduction
Cell Survival
Carcinogenesis/metabolism
Animals
Models, Biological
Proteomics
Cell Line, Tumor
Mice
Biomarkers, Tumor/metabolism
Źródło:
Christensen, A G, Ehmsen, S, Terp, M G, Batra, R, Alcaraz, N, Baumbach, J, Noer, J B, Moreira, J M A, Leth-Larsen, R, Larsen, M R & Ditzel, H J 2017, ' Elucidation of altered pathways in tumor-initiating cells of triple-negative breast cancer : A useful cell model system for drug screening ', Stem Cells, vol. 35, no. 8, pp. 1898–1912 . https://doi.org/10.1002/stem.2654
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b891f520ae1b7ed5a115596b35ab47ce
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fstem.2654

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