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Wyszukujesz frazę ""Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] NLMUID: 9107377"" wg kryterium: JN


Tytuł :
Anticancer properties of bisaminoquinolines with modified linkers.
Autorzy :
Wang Y; Department of Chemistry, University of Pennsylvania.
Jain V; Department of Medicine and Abramson Cancer Center, University of Pennsylvania.
Versace A; Department of Medicine and Abramson Cancer Center, University of Pennsylvania.
Bhardwaj M; Department of Medicine and Abramson Cancer Center, University of Pennsylvania.
Ann S Crissey M; Department of Medicine and Abramson Cancer Center, University of Pennsylvania.
Amaravadi RK; Department of Medicine and Abramson Cancer Center, University of Pennsylvania. Electronic address: .
Winkler JD; Department of Chemistry, University of Pennsylvania. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 20, pp. 128272. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Structural and Biophysical Characterization of the Burkholderia pseudomallei IspF Inhibitor L-Tryptophan Hydroxamate.
Autorzy :
Blain JM; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA.
Grote DL; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA.
Watkins SM; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA.
Goshu GM; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA.
Muller C; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA.
Gorman JL; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA.
Ranieri G; Shamrock Structures LLC, 1440 Davey Rd, Woodridge, IL 60208, USA.
Walter RL; Shamrock Structures LLC, 1440 Davey Rd, Woodridge, IL 60208, USA.
Hofstetter H; Department of Chemistry, Univeristy of Wisconsin Madison, WI 53706, USA.
Horn JR; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA. Electronic address: .
Hagen TJ; Department of Chemistry and Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL 60115, USA. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 20, pp. 128273. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Synthesis and Biological Evaluation of Platensic Alcohol as an Adamantane Surrogate in Antitumor Drug Lead Adaphostin.
Autorzy :
Wen Z; Xiangya International Academy of Translational Medicine at Central South University, Changsha, Hunan 410013, China.
Duan Y; Xiangya International Academy of Translational Medicine at Central South University, Changsha, Hunan 410013, China; Hunan Engineering Research Center of Combinatorial Biosynthesis and Natural Product Drug Discovery; National Engineering Research Center of Combinatorial Biosynthesis for Drug Discovery, Changsha, Hunan 410011, China.
Xiong Y; Xiangya International Academy of Translational Medicine at Central South University, Changsha, Hunan 410013, China.
Huang Y; Xiangya International Academy of Translational Medicine at Central South University, Changsha, Hunan 410013, China; National Engineering Research Center of Combinatorial Biosynthesis for Drug Discovery, Changsha, Hunan 410011, China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 17, pp. 128270. Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Discovery of Cinnoline Derivatives as Potent PI3K Inhibitors with Antiproliferative Activity.
Autorzy :
Tian C; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Yang C; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Wu T; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Lu M; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Chen Y; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Yang Y; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Liu X; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Ling Y; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Deng M; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China.
Jia Y; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China. Electronic address: .
Zhou Y; Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 17, pp. 128271. Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Design, synthesis and preliminary bioactivity evaluation of bitopic benzopyranomorpholine analogues as selective dopamine D3 receptor ligands as anti-drug addiction therapeutic agents.
Autorzy :
Cai J; School of Chemistry and Chemical Engineering, Southeast University, Nanjing, Jiangsu 211189, PR China. Electronic address: .
Huang M; School of Chemistry and Chemical Engineering, Southeast University, Nanjing, Jiangsu 211189, PR China.
Wang Y; School of Chemistry and Chemical Engineering, Southeast University, Nanjing, Jiangsu 211189, PR China.
Chen X; School of Chemistry and Chemical Engineering, Southeast University, Nanjing, Jiangsu 211189, PR China.
Ji M; School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, PR China.
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 17, pp. 128269. Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Synthesis of new methoxy derivatives of trans 2,3-diaryl-2,3-dihydrobenzofurans and evaluation of their anti-inflammatory activity.
Autorzy :
Laurita T; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Pappalardo I; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Chiummiento L; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
D'Orsi R; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Funicello M; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Santarsiero A; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Marsico M; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Infantino V; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Todisco S; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy.
Lupattelli P; Department of Sciences, University of Basilicata, via dell'ateneo lucano 10, 85100 Potenza, Italy. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 16, pp. 128264. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The combination of sesamol and clofibric acid moieties leads to a novel potent hypolipidemic agent with antioxidant, anti-inflammatory and hepatoprotective activity.
Autorzy :
Xie Y; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
Liu J; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xianyang 712046, People's Republic of China.
Shi Y; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xianyang 712046, People's Republic of China.
Wang B; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xianyang 712046, People's Republic of China.
Wang X; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
Wang W; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
Sun M; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
Xu X; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
Jiang H; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
Guo M; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
He Y; College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Ecomic Zone, Shaanxi Province 712046, People's Republic of China.
Ren C; First Hospital of Xi'an, Xi'an, Shaanxi Province 710002, People's Republic of China. Electronic address: .
Cheng L; Shaanxi Traffic Hospital, 276 Daxue South Road, Beilin District, Xi'an, Shannxi Province 710068, People's Republic of China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128121. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
New indenopyrazole linked oxadiazole conjugates as anti-pancreatic cancer agents: Design, synthesis, in silico studies including 3D-QSAR analysis.
Autorzy :
Khan I; Organic Synthesis and Process Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India; Academy of Scientific and Innovative Research, Ghaziabad 201002, India. Electronic address: .
Ganapathi T; Stem Cell Research Division, National Institute of Nutrition (NIN), Indian Council of Medical Research (ICMR), Hyderabad 500007, Telangana, India. Electronic address: .
Rehman MM; Catalysis and Fine Chemicals Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India. Electronic address: .
Shareef MA; Academy of Scientific and Innovative Research, Ghaziabad 201002, India; Centre for Fluoro-Agrochemicals, CSIR-Indian Institute of Chemical Technology, Tarnaka 500007, Hyderabad, India. Electronic address: .
Kumar CG; Organic Synthesis and Process Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India; Academy of Scientific and Innovative Research, Ghaziabad 201002, India.
Kamal A; Organic Synthesis and Process Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India; Academy of Scientific and Innovative Research, Ghaziabad 201002, India; School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi 110062, India. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128094. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Design, synthesis and antimicrobial activity of novel 2-aminothiophene containing cyclic and heterocyclic moieties.
Autorzy :
Asiri YI; Department of Pharmacology, College of Pharmacy, King Khalid University, P.O. Box 960, Abha 61421, Saudi Arabia. Electronic address: .
Muhsinah AB; Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia. Electronic address: .
Alsayari A; Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia. Electronic address: .
Venkatesan K; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia. Electronic address: .
Al-Ghorbani M; Department of Chemistry, College of Science and Arts, Ulla, Taibah University, Madina Monora, Saudi Arabia; Department of Chemistry, College of Education, Thamar University, Thamar, Yemen.
Mabkhot YN; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128117. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Discovery of N-(6-(5-fluoro-2-(piperidin-1-yl)phenyl)pyridazin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)methanesulfonamide as a brain-permeable and metabolically stable kynurenine monooxygenase inhibitor.
Autorzy :
Tsuboi K; Drug Research Division, Sumitomo Dainippon Pharma. Co., Ltd., 3-1-98, Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan.
Kimura H; Drug Research Division, Sumitomo Dainippon Pharma. Co., Ltd., 3-1-98, Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan.
Nakatsuji Y; Drug Research Division, Sumitomo Dainippon Pharma. Co., Ltd., 3-1-98, Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan.
Kassai M; Drug Research Division, Sumitomo Dainippon Pharma. Co., Ltd., 3-1-98, Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan.
Deai Y; Drug Research Division, Sumitomo Dainippon Pharma. Co., Ltd., 3-1-98, Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan.
Isobe Y; Drug Research Division, Sumitomo Dainippon Pharma. Co., Ltd., 3-1-98, Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128115. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Anti-chronic myeloid leukemia activity and quantitative structure-activity relationship of novel thiazole aminobenzamide derivatives.
Autorzy :
Zhang Y; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China; Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hengyang City, Hunan Province 421001, PR China.
Liu J; Department of Pharmacy, Yiyang Central Hospital, Hunan Province 413000, PR China.
Wu X; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Yang S; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Li Y; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Liu S; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Zhu S; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Cao X; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Xie Z; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Lei X; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China.
Huang H; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China; Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hengyang City, Hunan Province 421001, PR China. Electronic address: .
Peng J; Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang City, PR China; Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hengyang City, Hunan Province 421001, PR China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128116. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Discovery of a novel inhibitor of nitric oxide production with potential therapeutic effect on acute inflammation.
Autorzy :
Zhu LQ; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Fan XH; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Li JF; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Chen JH; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Liang Y; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Hu XL; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Ma SM; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Hao XY; Department of General Surgery, Gansu Provincial Hospital, Lanzhou 730000, China.
Shi T; School of Pharmacy, Lanzhou University, Lanzhou 730000, China. Electronic address: .
Wang Z; School of Pharmaceutical Science, University of South China, Hengyang 421001, China; School of Pharmacy, Lanzhou University, Lanzhou 730000, China; State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128106. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Semi-enzymatic synthesis of pseudouridine.
Autorzy :
Riley AT; Department of Chemistry, Southern Illinois University Edwardsville, Edwardsville, IL 62026, United States.
Sanford TC; Department of Chemistry, Southern Illinois University Edwardsville, Edwardsville, IL 62026, United States.
Woodard AM; Department of Chemistry, Southern Illinois University Edwardsville, Edwardsville, IL 62026, United States.
Clerc EP; Department of Chemistry, Southern Illinois University Edwardsville, Edwardsville, IL 62026, United States.
Sumita M; Department of Chemistry, Southern Illinois University Edwardsville, Edwardsville, IL 62026, United States. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128105. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The isolation, purification and complete characterization of the diterpene forskolin from nutritional supplements.
Autorzy :
Pritchard AO; Department of Chemistry, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada.
Nemez DB; Department of Chemistry, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada.
Herbert DE; Department of Chemistry, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada.
Dakshinamurti S; Department of Physiology, University of Manitoba, Winnipeg, Manitoba R3E 3P5, Canada.
Sorensen JL; Department of Chemistry, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128119. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Discovery of a new class of JMJD6 inhibitors and structure-activity relationship study.
Autorzy :
Wang T; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, PR China.
Zhang R; West China Hospital, Sichuan University, Chengdu 610041, PR China.
Liu Y; West China Hospital, Sichuan University, Chengdu 610041, PR China.
Fang Z; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, PR China.
Zhang H; West China Hospital, Sichuan University, Chengdu 610041, PR China.
Fan Y; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, PR China.
Yang S; West China Hospital, Sichuan University, Chengdu 610041, PR China.
Xiang R; Department of Medicinal Chemistry, School of Medicine, Nankai University, Tianjin 300071, PR China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128109. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Central residues of FSHβ (89-97) peptide are not critical for FSHR binding: Implications for peptidomimetic design.
Autorzy :
Prabhudesai KS; Biomedical Informatics Centre, ICMR-National Institute for Research in Reproductive Health, Mumbai 400012, Maharashtra, India.
Raje S; Biomedical Informatics Centre, ICMR-National Institute for Research in Reproductive Health, Mumbai 400012, Maharashtra, India.
Desai K; Biomedical Informatics Centre, ICMR-National Institute for Research in Reproductive Health, Mumbai 400012, Maharashtra, India.
Modi D; Molecular and Cellular Biology Laboratory, ICMR-National Institute for Research in Reproductive Health, JM Street, Parel, Mumbai 400012, Maharashtra, India.
Dighe V; National Center for Preclinical Reproductive and Genetic Toxicology, ICMR-National Institute for Research in Reproductive Health, Mumbai 400012, Maharashtra, India.
Contini A; Dipartimento di Scienze Farmaceutiche - Sezione di Chimica Generale e Organica 'Alessandro Marchesini', Università degli Studi di Milano, Via Venezian, 21, 20133 Milano, Italy.
Idicula-Thomas S; Biomedical Informatics Centre, ICMR-National Institute for Research in Reproductive Health, Mumbai 400012, Maharashtra, India. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128132. Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Discovery of novel N-1 substituted pyrazolopyrimidinones as potent, selective PDE2 inhibitors.
Autorzy :
Morriello GJ; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Rd., Kenilworth, NJ 07033, USA. Electronic address: .
Dwyer MP; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Rd., Kenilworth, NJ 07033, USA.
Chen Y; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Rd., Kenilworth, NJ 07033, USA.
Ginetti AT; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Rd., Kenilworth, NJ 07033, USA.
Xu S; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Rd., Kenilworth, NJ 07033, USA.
Lu J; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Abeywickrema P; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Wang D; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Crespo A; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Cabalu TD; Drug Metabolism, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Wilson JE; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Stachel SJ; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Paone DV; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
Sinz C; Discovery Chemistry, Merck & Co., Inc., 213 E. Grand Avenue, South San Fransisco, CA 94080, USA.
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128082. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Small molecule approaches to treat autoimmune and inflammatory diseases (Part II): Nucleic acid sensing antagonists and inhibitors.
Autorzy :
Wang X; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research and Early Development, Shanghai 201203, China.
Liu Y; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research and Early Development, Shanghai 201203, China.
Han X; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research and Early Development, Shanghai 201203, China.
Zou G; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research and Early Development, Shanghai 201203, China.
Zhu W; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research and Early Development, Shanghai 201203, China.
Shen H; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research and Early Development, Shanghai 201203, China.
Liu H; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research and Early Development, Shanghai 201203, China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128101. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Development of BET inhibitors as potential treatments for cancer: A search for structural diversity.
Autorzy :
Hill MD; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA. Electronic address: .
Fang H; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Tokarski J; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Fanslau C; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Haarhoff Z; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Huang C; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Kramer M; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Menard K; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Monereau L; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Morrison J; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Ranasinghe A; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Shields EE; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Tye CK; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Westhouse R; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Everlof G; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Sheriff S; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Yan C; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Marsilio F; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Zhang L; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Zvyaga T; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Lee F; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Gavai AV; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
Degnan AP; Bristol Myers Squibb Research and Development, 100 Binney St, Cambridge, MA 02142-1096, USA.
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128108. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Discovery of a novel series of substituted quinolines acting as anticancer agents and selective EGFR blocker: Molecular docking study.
Autorzy :
Kumar CBP; Department of Chemistry, Malnad College of Engineering, Hassan 573 202, India.
Raghu MS; Department of Chemistry, New Horizon College of Engineering, Bengaluru 560 103, India.
Prathibha BS; Department of Chemistry, B N M Institute of Technology, Bengaluru 560 070, India.
Prashanth MK; Department of Chemistry, B N M Institute of Technology, Bengaluru 560 070, India. Electronic address: .
Kanthimathi G; Department of Chemistry, Ramco Institute of Technology, Rajapalayam, Tamilnadu, 626117, India.
Kumar KY; Department of Chemistry, School of Engineering and Technology, Jain University, Ramanagara 562 112, India.
Parashuram L; Department of Chemistry, New Horizon College of Engineering, Bengaluru 560 103, India.
Alharthi FA; Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jul 15; Vol. 44, pp. 128118. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
Czasopismo naukowe

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