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Wyszukujesz frazę ""Biosynthetic Pathways"" wg kryterium: Temat


Tytuł :
Microbial production of multiple short-chain primary amines via retrobiosynthesis.
Autorzy :
Kim DI; Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering, KAIST Institute for BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, KAIST, Daejeon, 34141, Republic of Korea.
Chae TU; Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering, KAIST Institute for BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, KAIST, Daejeon, 34141, Republic of Korea.
Kim HU; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, KAIST, Daejeon, 34141, Republic of Korea.; Systems Biology and Medicine Laboratory, Department of Chemical and Biomolecular Engineering, KAIST, Daejeon, 34141, Republic of Korea.; KAIST Institute for Artificial Intelligence, BioProcess Engineering Research Center and BioInformatics Research Center, KAIST, Daejeon, 34141, Republic of Korea.
Jang WD; Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering, KAIST Institute for BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, KAIST, Daejeon, 34141, Republic of Korea.
Lee SY; Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering, KAIST Institute for BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. .; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, KAIST, Daejeon, 34141, Republic of Korea. .; KAIST Institute for Artificial Intelligence, BioProcess Engineering Research Center and BioInformatics Research Center, KAIST, Daejeon, 34141, Republic of Korea. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 08; Vol. 12 (1), pp. 173. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*/genetics
Protein Engineering*
Amines/*chemistry
Amines/*metabolism
Carboxy-Lyases/genetics ; Carboxy-Lyases/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Fermentation ; Glucose/metabolism ; Industrial Microbiology ; Metabolic Engineering ; Molecular Docking Simulation ; Streptomyces/enzymology ; Streptomyces/genetics ; Streptomyces/metabolism
SCR Organism :
Streptomyces viridifaciens
Czasopismo naukowe
Tytuł :
Connecting moss lipid droplets to patchoulol biosynthesis.
Autorzy :
Peramuna A; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Bae H; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.; Mosspiration Biotech, Hørsholm, Denmark.
Quiñonero López C; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Fromberg A; National Food Institute, Technical University of Denmark, Lyngby, Denmark.
Petersen B; The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.; Centre of Excellence for Omics-Driven Computational Biodiscovery, AIMST University, Kedah, Malaysia.
Simonsen HT; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.; Mosspiration Biotech, Hørsholm, Denmark.
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Źródło :
PloS one [PLoS One] 2020 Dec 07; Vol. 15 (12), pp. e0243620. Date of Electronic Publication: 2020 Dec 07 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Bryopsida/*metabolism
Lipid Droplets/*metabolism
Sesquiterpenes/*metabolism
Bryopsida/enzymology ; Isomerases/metabolism ; Plant Proteins/metabolism
Czasopismo naukowe
Tytuł :
Pathway engineering in yeast for synthesizing the complex polyketide bikaverin.
Autorzy :
Zhao M; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, 300072, Tianjin, PR China.; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, 300072, Tianjin, PR China.; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, 10016, USA.
Zhao Y; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, 10016, USA.
Yao M; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, 300072, Tianjin, PR China.; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, 300072, Tianjin, PR China.
Iqbal H; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, 10016, USA.
Hu Q; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, 300072, Tianjin, PR China.; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, 300072, Tianjin, PR China.
Liu H; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, 300072, Tianjin, PR China.; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, 300072, Tianjin, PR China.
Qiao B; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, 300072, Tianjin, PR China.; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, 300072, Tianjin, PR China.
Li C; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, 300072, Tianjin, PR China.; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, 300072, Tianjin, PR China.
Skovbjerg CAS; Section for Synthetic Biology, Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 223, Kongens Lyngby, Denmark.
Nielsen JC; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark.
Frandsen RJN; Section for Synthetic Biology, Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 223, Kongens Lyngby, Denmark.
Yuan Y; Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, 300072, Tianjin, PR China.; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, 300072, Tianjin, PR China.
Boeke JD; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, 10016, USA. .; Department of Biomedical Engineering, NYU Tandon School of Engineering, Brooklyn, NY, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 03; Vol. 11 (1), pp. 6197. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biosynthetic Pathways*
Metabolic Engineering*
Polyketides/*metabolism
Saccharomyces cerevisiae/*metabolism
Xanthones/*metabolism
Green Fluorescent Proteins/metabolism ; Polyketides/chemistry ; Xanthones/chemistry
Czasopismo naukowe
Tytuł :
Metabolic engineering for production of functional polysaccharides.
Autorzy :
Schilling C; Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus for Biotechnology and Sustainability, 94315 Straubing, Germany.
Badri A; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Sieber V; Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus for Biotechnology and Sustainability, 94315 Straubing, Germany.
Koffas M; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA; Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA. Electronic address: .
Schmid J; Norwegian University of Science and Technology, Department of Biotechnology and Food Science, Sem Sælands vei 6-8, 7491 Trondheim, Norway. Electronic address: .
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Źródło :
Current opinion in biotechnology [Curr Opin Biotechnol] 2020 Dec; Vol. 66, pp. 44-51. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Biosynthetic Pathways*
Metabolic Engineering*
Polysaccharides
Czasopismo naukowe
Tytuł :
Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Autorzy :
Wang ZL; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Gao HM; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Peking University, 100191 Beijing, China.; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, 100191 Beijing, China.
Wang S; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Zhang M; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Chen K; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Zhang YQ; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Wang HD; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Han BY; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Xu LL; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China.
Song TQ; Institute of Plant Protection, Jiangsu Academy of Agricultural Science, 210014 Nanjing, China.
Yun CH; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Peking University, 100191 Beijing, China.
Qiao X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China; .
Ye M; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 100191 Beijing, China; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 01; Vol. 117 (48), pp. 30816-30823. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Plant Physiological Phenomena*
Glycosides/*biosynthesis
Plant Proteins/*metabolism
Catalysis ; Cloning, Molecular ; Enzyme Activation ; Flavonoids/biosynthesis ; Glycosides/chemistry ; Glycosylation ; Glycosyltransferases/chemistry ; Glycosyltransferases/genetics ; Glycosyltransferases/metabolism ; Models, Molecular ; Plant Proteins/chemistry ; Plant Proteins/genetics ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Diamine Biosynthesis: Research Progress and Application Prospects.
Autorzy :
Wang L; National Engineering Laboratory for Cereal Fermentation Technology (NELCF), Jiangnan University, Wuxi, Jiangsu, China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi, Jiangsu, China.
Li G; National Engineering Laboratory for Cereal Fermentation Technology (NELCF), Jiangnan University, Wuxi, Jiangsu, China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi, Jiangsu, China.
Deng Y; National Engineering Laboratory for Cereal Fermentation Technology (NELCF), Jiangnan University, Wuxi, Jiangsu, China .; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi, Jiangsu, China.
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Źródło :
Applied and environmental microbiology [Appl Environ Microbiol] 2020 Nov 10; Vol. 86 (23). Date of Electronic Publication: 2020 Nov 10 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Biocatalysis*
Biosynthetic Pathways*
Bacteria/*metabolism
Diamines/*metabolism
Metabolic Engineering/*methods
Nylons/chemistry
Czasopismo naukowe
Tytuł :
Rhodoquinone in bacteria and animals: Two distinct pathways for biosynthesis of this key electron transporter used in anaerobic bioenergetics.
Autorzy :
Salinas G; Laboratorio de Biología de Gusanos, Unidad Mixta, Departamento de Biociencias, Facultad de Química, Universidad de la República - Institut Pasteur de Montevideo, Montevideo, Uruguay.
Langelaan DN; Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Shepherd JN; Department of Chemistry and Biochemistry, Gonzaga University, Spokane, Washington, United States. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Bioenergetics [Biochim Biophys Acta Bioenerg] 2020 Nov 01; Vol. 1861 (11), pp. 148278. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Biosynthetic Pathways*
Electrons*
Energy Metabolism*
Bacteria/*metabolism
Ubiquinone/*analogs & derivatives
Anaerobiosis ; Animals ; Electron Transport ; Ubiquinone/metabolism
Czasopismo naukowe
Tytuł :
Transcriptome sequencing and endogenous phytohormone analysis reveal new insights in CPPU controlling fruit development in kiwifruit (Actinidia chinensis).
Autorzy :
Wu L; Institute of Special Plants, Chongqing Key Laboratory of Economic Plant Biotechnology, Chongqing University of Arts and Sciences, Yongchuan, Chongqing, China.
Lan J; Institute of Special Plants, Chongqing Key Laboratory of Economic Plant Biotechnology, Chongqing University of Arts and Sciences, Yongchuan, Chongqing, China.
Xiang X; Institute of Special Plants, Chongqing Key Laboratory of Economic Plant Biotechnology, Chongqing University of Arts and Sciences, Yongchuan, Chongqing, China.
Xiang H; Institute of Special Plants, Chongqing Key Laboratory of Economic Plant Biotechnology, Chongqing University of Arts and Sciences, Yongchuan, Chongqing, China.
Jin Z; Institute of Special Plants, Chongqing Key Laboratory of Economic Plant Biotechnology, Chongqing University of Arts and Sciences, Yongchuan, Chongqing, China.
Khan S; Department of Biological Sciences, University of Toronto, Scarborough, Ontario, Canada.
Liu Y; College of Horticulture and Gardening, Institute of Horticulture Plants, Yangtze University, Jingzhou, Hubei, China.
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Źródło :
PloS one [PLoS One] 2020 Oct 12; Vol. 15 (10), pp. e0240355. Date of Electronic Publication: 2020 Oct 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Actinidia/*growth & development
Gene Expression Profiling/*methods
Plant Growth Regulators/*genetics
Plant Growth Regulators/*metabolism
Abscisic Acid/metabolism ; Actinidia/genetics ; Actinidia/metabolism ; Fruit/genetics ; Fruit/growth & development ; Gene Expression Regulation, Plant ; Gibberellins/metabolism ; Indoleacetic Acids/metabolism ; Plant Proteins/genetics ; Sequence Analysis, RNA ; Zeatin/metabolism
Czasopismo naukowe
Tytuł :
Titrating bacterial growth and chemical biosynthesis for efficient N-acetylglucosamine and N-acetylneuraminic acid bioproduction.
Autorzy :
Tian R; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China.
Liu Y; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China. .; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China. .
Cao Y; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China.
Zhang Z; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China.
Li J; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China.
Liu L; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China.
Du G; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China.
Chen J; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China. .; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 08; Vol. 11 (1), pp. 5078. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Acetylglucosamine/*metabolism
Bacillus subtilis/*growth & development
Escherichia coli/*growth & development
N-Acetylneuraminic Acid/*metabolism
Bacillus subtilis/metabolism ; Cell Proliferation ; Escherichia coli/metabolism ; Genetic Code ; Green Fluorescent Proteins/metabolism ; Metabolic Engineering ; Metabolic Flux Analysis ; Promoter Regions, Genetic/genetics ; RNA, Transfer/genetics ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł :
Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation.
Autorzy :
Zhang X; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: .
Lin K; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: .
Li Y; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China. Electronic address: .
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Źródło :
Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2020 Oct; Vol. 155, pp. 637-649. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biosynthetic Pathways*
Phytosterols/*metabolism
Plants/*enzymology
Enzymes/metabolism ; Feedback, Physiological ; Plant Proteins/metabolism ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Phylogenomics reveals convergent evolution of red-violet coloration in land plants and the origins of the anthocyanin biosynthetic pathway.
Autorzy :
Piatkowski BT; Department of Biology, Duke University, Durham, NC 27708, United States. Electronic address: .
Imwattana K; Department of Biology, Duke University, Durham, NC 27708, United States.
Tripp EA; Department of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO 80309, United States.
Weston DJ; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, United States; Climate Change Science Institute, Oak Ridge National Laboratory, Oak Ridge, TN 37831, United States.
Healey A; HudsonAlpha Institute of Biotechnology, Huntsville, AL 35806, United States.
Schmutz J; HudsonAlpha Institute of Biotechnology, Huntsville, AL 35806, United States; Department of Energy Joint Genome Institute, Berkeley, CA 94720, United States.
Shaw AJ; Department of Biology, Duke University, Durham, NC 27708, United States.
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Źródło :
Molecular phylogenetics and evolution [Mol Phylogenet Evol] 2020 Oct; Vol. 151, pp. 106904. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biosynthetic Pathways*/genetics
Phylogeny*
Anthocyanins/*biosynthesis
Embryophyta/*genetics
Pigmentation/*genetics
Anthocyanins/genetics ; Base Sequence ; Flavonoids/chemistry ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Species Specificity
Czasopismo naukowe
Tytuł :
Multiplex Design of the Metabolic Network for Production of l-Homoserine in Escherichia coli.
Autorzy :
Liu P; National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China.; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Zhang B; National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China.; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Yao ZH; National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China.; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Liu ZQ; National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China .; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Zheng YG; National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China.; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
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Źródło :
Applied and environmental microbiology [Appl Environ Microbiol] 2020 Oct 01; Vol. 86 (20). Date of Electronic Publication: 2020 Oct 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Escherichia coli/*metabolism
Homoserine/*metabolism
Metabolic Engineering/*methods
Czasopismo naukowe
Tytuł :
Functional analysis of β-ketoacyl-CoA synthase from biofuel feedstock Thlaspi arvense reveals differences in the triacylglycerol biosynthetic pathway among Brassicaceae.
Autorzy :
Claver A; Department of Plant Nutrition, Estación Experimental de Aula Dei-CSIC, Avda. Montañana 1005, 50059, Zaragoza, Spain.
de la Vega M; Department of Plant Nutrition, Estación Experimental de Aula Dei-CSIC, Avda. Montañana 1005, 50059, Zaragoza, Spain.
Rey-Giménez R; Laboratorio Agroambiental, Gobierno de Aragón, Avda. Montañana 1005, 50071, Zaragoza, Spain.
Luján MÁ; Department of Plant Nutrition, Estación Experimental de Aula Dei-CSIC, Avda. Montañana 1005, 50059, Zaragoza, Spain.
Picorel R; Department of Plant Nutrition, Estación Experimental de Aula Dei-CSIC, Avda. Montañana 1005, 50059, Zaragoza, Spain.
López MV; Department of Soil and Water, Estación Experimental de Aula Dei-CSIC, Avda. Montañana 1005, 50059, Zaragoza, Spain.
Alfonso M; Department of Plant Nutrition, Estación Experimental de Aula Dei-CSIC, Avda. Montañana 1005, 50059, Zaragoza, Spain. .
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Źródło :
Plant molecular biology [Plant Mol Biol] 2020 Oct; Vol. 104 (3), pp. 283-296. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Biofuels*
Biosynthetic Pathways*/genetics
3-Oxoacyl-(Acyl-Carrier-Protein) Synthase/*metabolism
Brassicaceae/*metabolism
Thlaspi/*enzymology
Thlaspi/*metabolism
Triglycerides/*biosynthesis
1-Acylglycerophosphocholine O-Acyltransferase/metabolism ; 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase/genetics ; Acyltransferases/metabolism ; Amino Acid Sequence ; Arabidopsis Proteins/metabolism ; Diacylglycerol O-Acyltransferase/metabolism ; Erucic Acids/metabolism ; Fatty Acid Elongases/genetics ; Fatty Acid Elongases/metabolism ; Fatty Acids/metabolism ; Gene Expression Regulation, Plant ; Phenotype ; Plant Oils/metabolism ; Plants, Genetically Modified ; Seeds/genetics ; Sequence Analysis ; Thlaspi/genetics ; Transcriptome
Czasopismo naukowe
Tytuł :
UPLC-MS-based urine nontargeted metabolic profiling identifies dysregulation of pantothenate and CoA biosynthesis pathway in diabetic kidney disease.
Autorzy :
Ma T; Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China.
Liu T; Key Laboratory of Health Cultivation of the Ministry of Education, Beijing University of Chinese Medicine, Beijing 100029, China.
Xie P; Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China.
Jiang S; The First Teaching Hospital of Xinjiang Medical University, Urumuqi 830013, China.
Yi W; Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China.
Dai P; Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China.
Guo X; Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118160. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Biosynthetic Pathways*
Coenzyme A/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Diabetic Nephropathies/*metabolism
Pantothenic Acid/*metabolism
Chromatography, High Pressure Liquid ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/urine ; Diabetic Nephropathies/etiology ; Diabetic Nephropathies/urine ; Female ; Humans ; Male ; Mass Spectrometry ; Metabolome ; Middle Aged
Czasopismo naukowe
Tytuł :
Esterified carotenoids are synthesized in petals of carnation (Dianthus caryophyllus) and accumulate in differentiated chromoplasts.
Autorzy :
Iijima L; Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.
Kishimoto S; Institute of Vegetable and Floriculture Science, National Agriculture and Food Research Organization (NARO), 2-1 Fujimoto, Tsukuba, Ibaraki, 305-0852, Japan. .
Ohmiya A; Institute of Vegetable and Floriculture Science, National Agriculture and Food Research Organization (NARO), 2-1 Fujimoto, Tsukuba, Ibaraki, 305-0852, Japan.
Yagi M; Institute of Vegetable and Floriculture Science, National Agriculture and Food Research Organization (NARO), 2-1 Fujimoto, Tsukuba, Ibaraki, 305-0852, Japan.
Okamoto E; Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.
Miyahara T; Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.; Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan.
Tsujimoto T; Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.; National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.
Ozeki Y; Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.
Uchiyama N; National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.
Hakamatsuka T; National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.
Kouno T; Japan Agribio Company Limited, 110-5 Itayamachi, Naka-ku, Hamamatsu, Shizuoka, 430-0928, Japan.
Cano EA; Barberet & Blanc S. A., Camino Viejo 205, 30890, Puerto Lumbreras, Murcia, Spain.
Shimizu M; Iwate Biotechnology Research Center, 22-174-4 Narita, Kitakami, Iwate, 024-0003, Japan.
Nishihara M; Iwate Biotechnology Research Center, 22-174-4 Narita, Kitakami, Iwate, 024-0003, Japan.
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 16; Vol. 10 (1), pp. 15256. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Carotenoids/*metabolism
Dianthus/*growth & development
Plastids/*metabolism
Carotenoids/chemistry ; Dianthus/genetics ; Dianthus/metabolism ; Esterification ; Flowers/genetics ; Flowers/growth & development ; Flowers/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Plant ; Plant Proteins/genetics ; Plastids/genetics ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
Development of screening methods for functional characterization of UGTs from Stevia rebaudiana.
Autorzy :
Petit E; Equipe Physiologie, Pathologie et Génétique Végétales (PPGV), INP-PURPAN, Université de Toulouse, 75 voie du TOEC, BP 57611, 31076, Toulouse Cedex 03, France.
Berger M; Equipe Physiologie, Pathologie et Génétique Végétales (PPGV), INP-PURPAN, Université de Toulouse, 75 voie du TOEC, BP 57611, 31076, Toulouse Cedex 03, France. .
Camborde L; Laboratoire de Recherche en Sciences Végétales (LRSV), CNRS, Université Paul Sabatier (UPS), Toulouse, France.
Vallejo V; PepsiCo, 700 Anderson Hill Rd., Purchase, NY, 10577, USA.
Daydé J; Equipe Physiologie, Pathologie et Génétique Végétales (PPGV), INP-PURPAN, Université de Toulouse, 75 voie du TOEC, BP 57611, 31076, Toulouse Cedex 03, France.
Jacques A; Equipe Physiologie, Pathologie et Génétique Végétales (PPGV), INP-PURPAN, Université de Toulouse, 75 voie du TOEC, BP 57611, 31076, Toulouse Cedex 03, France.
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 15; Vol. 10 (1), pp. 15137. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Diterpenes, Kaurane/*metabolism
Glucosides/*metabolism
Glycosyltransferases/*metabolism
Plant Proteins/*metabolism
Stevia/*enzymology
Uridine Diphosphate/*metabolism
Glycosylation ; Glycosyltransferases/genetics ; Plant Proteins/genetics ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
Inhibition of the glutathione biosynthetic pathway increases phytochemical toxicity to Spodoptera litura and Nilaparvata lugens.
Autorzy :
Cen Y; Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China; Guangzhou Key Laboratory of Insect Development Regulation and Applied Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Zou X; Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China; Guangzhou Key Laboratory of Insect Development Regulation and Applied Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Li L; Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China; Guangzhou Key Laboratory of Insect Development Regulation and Applied Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Chen S; Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China; Guangzhou Key Laboratory of Insect Development Regulation and Applied Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Lin Y; Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China; Guangzhou Key Laboratory of Insect Development Regulation and Applied Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Liu L; Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China; Guangzhou Key Laboratory of Insect Development Regulation and Applied Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Zheng S; Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China; Guangzhou Key Laboratory of Insect Development Regulation and Applied Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China. Electronic address: .
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Źródło :
Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2020 Sep; Vol. 168, pp. 104632. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Biosynthetic Pathways*
Glutathione*
Animals ; Larva ; Phytochemicals ; Spodoptera
Czasopismo naukowe
Tytuł :
Palantir: a springboard for the analysis of secondary metabolite gene clusters in large-scale genome mining projects.
Autorzy :
Meunier L; InBioS-PhytoSYSTEMS, Eukaryotic Phylogenomics, University of Liège, B-4000 Liège, Belgium.; Microbial Processes and Interactions, TERRA Teaching and Research Centre, Joint Research Unit BioEcoAgro UMRT 1158, Gembloux Agro-Bio Tech, University of Liège, B-5030 Gembloux, Belgium.
Tocquin P; InBioS-PhytoSYSTEMS, Plant Physiology, University of Liège, B-4000 Liège, Belgium.; Hedera-22 SCRL, B-4130 Tilff, Belgium.
Cornet L; GIGA institute, Medical Genomics-Unit of Animal Genomics, University of Liège, B-4000 Liège, Belgium.
Sirjacobs D; InBioS-PhytoSYSTEMS, Eukaryotic Phylogenomics, University of Liège, B-4000 Liège, Belgium.
Leclère V; Univ. Lille, INRA, ISA, Univ. Artois, Univ. Littoral Côte d'Opale, EA 7394-ICV-Institut Charles Viollette, Joint Research Unit BioEcoAgro UMRT 1158, F-59000 Lille, France.
Pupin M; UMR 9189- CRIStAL- Centre de Recherche en Informatique Signal et Automatique de Lille, University of Lille, CNRS, Centrale Lille, F-59000 Lille, France.; Bonsai Team, Inria-Lille Nord Europe, F-59655 Villeneuve d'Ascq Cedex, France.
Jacques P; Microbial Processes and Interactions, TERRA Teaching and Research Centre, Joint Research Unit BioEcoAgro UMRT 1158, Gembloux Agro-Bio Tech, University of Liège, B-5030 Gembloux, Belgium.
Baurain D; InBioS-PhytoSYSTEMS, Eukaryotic Phylogenomics, University of Liège, B-4000 Liège, Belgium.; Hedera-22 SCRL, B-4130 Tilff, Belgium.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2020 Aug 01; Vol. 36 (15), pp. 4345-4347.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways*
Software*
Bacteria/genetics ; Molecular Sequence Annotation ; Multigene Family
Czasopismo naukowe
Tytuł :
In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design.
Autorzy :
Karim AS; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.
Dudley QM; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.
Juminaga A; LanzaTech Inc., Skokie, IL, USA.
Yuan Y; LanzaTech Inc., Skokie, IL, USA.
Crowe SA; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.
Heggestad JT; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.
Garg S; LanzaTech Inc., Skokie, IL, USA.
Abdalla T; LanzaTech Inc., Skokie, IL, USA.
Grubbe WS; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.
Rasor BJ; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA.; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.
Coar DN; Lockheed Martin Advanced Technology Laboratories, Cherry Hill, NJ, USA.
Torculas M; Lockheed Martin Advanced Technology Laboratories, Cherry Hill, NJ, USA.
Krein M; Lockheed Martin Advanced Technology Laboratories, Cherry Hill, NJ, USA.
Liew FE; LanzaTech Inc., Skokie, IL, USA.
Quattlebaum A; LanzaTech Inc., Skokie, IL, USA.
Jensen RO; LanzaTech Inc., Skokie, IL, USA.
Stuart JA; Lockheed Martin Advanced Technology Laboratories, Cherry Hill, NJ, USA.
Simpson SD; LanzaTech Inc., Skokie, IL, USA.
Köpke M; LanzaTech Inc., Skokie, IL, USA. .
Jewett MC; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA. .; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA. .; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA. .; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA. .; Simpson Querrey Institute, Northwestern University, Chicago, IL, USA. .
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Źródło :
Nature chemical biology [Nat Chem Biol] 2020 Aug; Vol. 16 (8), pp. 912-919. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biosynthetic Pathways/*physiology
Metabolic Engineering/*methods
Synthetic Biology/*methods
Biosynthetic Pathways/drug effects ; Biotechnology/methods ; Cell-Free System/metabolism ; Metabolic Networks and Pathways/physiology ; Protein Biosynthesis/genetics ; Protein Biosynthesis/physiology
Czasopismo naukowe
Tytuł :
Doing the gene shuffle to close synteny: dynamic assembly of biosynthetic gene clusters.
Autorzy :
Peters RJ; Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA, 50011, USA.
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Źródło :
The New phytologist [New Phytol] 2020 Aug; Vol. 227 (4), pp. 992-994. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Biosynthetic Pathways*
Brassicaceae*
Genomics ; Multigene Family ; Synteny/genetics
Czasopismo naukowe

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