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Tytuł :
SH-SY5Y and LUHMES cells display differential sensitivity to MPP+, tunicamycin, and epoxomicin in 2D and 3D cell culture.
Autorzy :
Ko KR; School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
Tam NW; School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
Teixeira AG; School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
Frampton JP; School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2020 Mar; Vol. 36 (2), pp. e2942. Date of Electronic Publication: 2019 Dec 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques*
1-Methyl-4-phenylpyridinium/*pharmacology
Neurotoxins/*pharmacology
Tunicamycin/*pharmacology
Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Humans ; Oligopeptides/pharmacology
Czasopismo naukowe
Tytuł :
A population balance model to modulate shear for the control of aggregation in Taxus suspension cultures.
Autorzy :
Wilson SA; Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts.
Maindarkar SN; Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts.
McKee MC; Departement of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts.
Vilkhovoy M; Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts.
Henson MA; Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts.
Roberts SC; Department of Chemical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2020 Mar; Vol. 36 (2), pp. e2932. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Culture Techniques*
Models, Biological*
Taxus/*cytology
Cell Aggregation ; Cell Survival
Czasopismo naukowe
Tytuł :
Impact of the type of microcarrier and agitation modes on the expansion performances of mesenchymal stem cells derived from umbilical cord.
Autorzy :
Loubière C; Laboratoire Réactions et Génie des Procédés, Université de Lorraine, CNRS, Nancy, France.
Sion C; Laboratoire Réactions et Génie des Procédés, Université de Lorraine, CNRS, Nancy, France.
De Isla N; CNRS, IMoPA, UMR 7365, Vandoeuvre-lès-Nancy, France.; Université de Lorraine, Faculté de Médecine, Vandoeuvre-lès-Nancy, France.
Reppel L; CNRS, IMoPA, UMR 7365, Vandoeuvre-lès-Nancy, France.; CHRU de Nancy, Unité de Thérapie cellulaire et Tissus and FR 3209, Vandoeuvre-lès-Nancy, France.; Faculté de Pharmacie, Département de Microbiologie-Immunologie, Université de Lorraine, Nancy, France.
Guedon E; Laboratoire Réactions et Génie des Procédés, Université de Lorraine, CNRS, Nancy, France.
Chevalot I; Laboratoire Réactions et Génie des Procédés, Université de Lorraine, CNRS, Nancy, France.
Olmos E; Laboratoire Réactions et Génie des Procédés, Université de Lorraine, CNRS, Nancy, France.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Nov; Vol. 35 (6), pp. e2887. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques/*methods
Dextrans/*chemistry
Mesenchymal Stem Cells/*cytology
Umbilical Cord/*cytology
Culture Media/chemistry ; Culture Media/pharmacology ; Glutamine/chemistry ; Glutamine/pharmacology ; Humans
Czasopismo naukowe
Tytuł :
Superfluous glutamine synthetase activity in Chinese Hamster Ovary cells selected under glutamine limitation is growth limiting in glutamine-replete conditions and can be inhibited by serine.
Autorzy :
Maralingannavar V; Chemical Engineering and Process Development Division, CSIR-National Chemical Laboratory, Pune, Maharashtra, India.; Academy of Scientific and Innovative Research (AcSIR), CSIR-National Chemical Laboratory Campus, Ghaziabad, Uttar Pradesh, India.
Parmar D; Chemical Engineering and Process Development Division, CSIR-National Chemical Laboratory, Pune, Maharashtra, India.; Academy of Scientific and Innovative Research (AcSIR), CSIR-National Chemical Laboratory Campus, Ghaziabad, Uttar Pradesh, India.
Panchagnula V; Chemical Engineering and Process Development Division, CSIR-National Chemical Laboratory, Pune, Maharashtra, India.; Academy of Scientific and Innovative Research (AcSIR), CSIR-National Chemical Laboratory Campus, Ghaziabad, Uttar Pradesh, India.
Gadgil M; Chemical Engineering and Process Development Division, CSIR-National Chemical Laboratory, Pune, Maharashtra, India.; Academy of Scientific and Innovative Research (AcSIR), CSIR-National Chemical Laboratory Campus, Ghaziabad, Uttar Pradesh, India.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Sep; Vol. 35 (5), pp. e2856. Date of Electronic Publication: 2019 Jun 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glutamate-Ammonia Ligase*/antagonists & inhibitors
Glutamate-Ammonia Ligase*/metabolism
Cell Culture Techniques/*methods
Glutamine/*metabolism
Serine/*metabolism
Animals ; CHO Cells ; Carbon Isotopes/analysis ; Carbon Isotopes/metabolism ; Cricetinae ; Cricetulus ; Culture Media/chemistry ; Culture Media/metabolism ; Glutamine/analysis ; Methionine Sulfoximine
Czasopismo naukowe
Tytuł :
Novel electrodynamic oscillation technique enables enhanced mass transfer and mixing for cultivation in micro-bioreactor.
Autorzy :
Frey LJ; Institute of Biochemical Engineering, Technische Universität Braunschweig, Braunschweig, Germany.; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.
Vorländer D; Institute of Biochemical Engineering, Technische Universität Braunschweig, Braunschweig, Germany.; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.
Rasch D; Institute of Biochemical Engineering, Technische Universität Braunschweig, Braunschweig, Germany.; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.
Ostsieker H; Institute of Biochemical Engineering, Technische Universität Braunschweig, Braunschweig, Germany.; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.
Müller B; Institute of Analytical Chemistry and Food Chemistry, Graz University of Technologies, Graz, Austria.
Schulze M; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.; Institute of Energy and Process Systems Engineering, Technische Universität Braunschweig, Braunschweig, Germany.
Schenkendorf R; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.; Institute of Energy and Process Systems Engineering, Technische Universität Braunschweig, Braunschweig, Germany.
Mayr T; Institute of Analytical Chemistry and Food Chemistry, Graz University of Technologies, Graz, Austria.
Grosch JH; Institute of Biochemical Engineering, Technische Universität Braunschweig, Braunschweig, Germany.; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.
Krull R; Institute of Biochemical Engineering, Technische Universität Braunschweig, Braunschweig, Germany.; Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Sep; Vol. 35 (5), pp. e2827. Date of Electronic Publication: 2019 May 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bioreactors*
Cell Culture Techniques/*instrumentation
Microtechnology/*instrumentation
Oxygen/*metabolism
Equipment Design ; Escherichia coli
Czasopismo naukowe
Tytuł :
Development of an alternating tangential flow (ATF) perfusion-based transient gene expression (TGE) bioprocess for universal influenza vaccine.
Autorzy :
Hong J; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
Demirji J; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
Blackstock D; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
Lee J; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
Dinh T; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
Goh A; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
Arnold F; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
Horwitz J; Vaccine Production Program Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institute of Health, Gaithersburg, Maryland.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Sep; Vol. 35 (5), pp. e2831. Date of Electronic Publication: 2019 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Bioreactors*
Influenza Vaccines*/chemistry
Influenza Vaccines*/genetics
Influenza Vaccines*/metabolism
Cell Culture Techniques/*methods
Cell Count ; Cell Survival/physiology ; Gene Expression ; HEK293 Cells ; Humans ; Nanoparticles ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
Improvements in single-use bioreactor film material composition leads to robust and reliable Chinese hamster ovary cell performance.
Autorzy :
Kelly PS; National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Dorival-García N; National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Paré S; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Carillo S; National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Ta C; National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Alarcon Miguez A; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland.
Coleman O; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland.
Harper E; Institute for Global Food Security, School of Biological Sciences, Queen's University, Belfast, Northern Ireland, UK.
Shannon M; Institute for Global Food Security, School of Biological Sciences, Queen's University, Belfast, Northern Ireland, UK.
Henry M; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland.
Connolly L; Institute for Global Food Security, School of Biological Sciences, Queen's University, Belfast, Northern Ireland, UK.
Clynes M; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Meleady P; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Bones J; National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
Barron N; National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin, Ireland.; Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick, Ireland.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Jul; Vol. 35 (4), pp. e2824. Date of Electronic Publication: 2019 May 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bioreactors*
Cell Culture Techniques*
Culture Media, Conditioned/*chemistry
Animals ; CHO Cells ; Cell Proliferation ; Cell Survival ; Cells, Cultured ; Chromatography, Liquid ; Cricetinae ; Cricetulus ; Proteomics ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Using CFD simulations and statistical analysis to correlate oxygen mass transfer coefficient to both geometrical parameters and operating conditions in a stirred-tank bioreactor.
Autorzy :
Amer M; Chemical Engineering, Oklahoma State University, Stillwater, Oklahoma.
Feng Y; Chemical Engineering, Oklahoma State University, Stillwater, Oklahoma.
Ramsey JD; Chemical Engineering, Oklahoma State University, Stillwater, Oklahoma.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 May; Vol. 35 (3), pp. e2785. Date of Electronic Publication: 2019 Mar 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Culture Techniques/*instrumentation
Oxygen/*chemistry
Bioreactors ; Gases/chemistry ; Hydrodynamics ; Kinetics ; Mathematical Computing
Czasopismo naukowe
Tytuł :
Expansion of retinal stem cells and their progeny using cell microcarriers in a bioreactor.
Autorzy :
Baakdhah T; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
van der Kooy D; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 May; Vol. 35 (3), pp. e2800. Date of Electronic Publication: 2019 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques/*instrumentation
Retina/*cytology
Stem Cells/*cytology
Animals ; Bioreactors ; Cell Differentiation ; Cell Proliferation ; Mice ; Mice, Inbred C57BL ; Microspheres
Czasopismo naukowe
Tytuł :
Identification of upstream culture conditions and harvest time parameters that affect host cell protein clearance.
Autorzy :
Wilson LJ; Department of Biochemical Engineering, University College London, London, UK.; Department of Biopharm Process Research, GlaxoSmithKline, Stevenage, Herts, UK.
Lewis W; Department of Biopharm Process Research, GlaxoSmithKline, Stevenage, Herts, UK.
Kucia-Tran R; Department of Biopharm Process Research, GlaxoSmithKline, Stevenage, Herts, UK.
Bracewell DG; Department of Biochemical Engineering, University College London, London, UK.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 May; Vol. 35 (3), pp. e2805. Date of Electronic Publication: 2019 Mar 28.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques/*methods
Chromatography, Affinity/*methods
Immunoglobulin G/*isolation & purification
Immunoglobulin G/*metabolism
Animals ; Bioreactors ; CHO Cells ; Cricetinae ; Cricetulus ; Staphylococcal Protein A/chemistry ; Time Factors
Czasopismo naukowe
Tytuł :
Optimization of pH induced flocculation of marine and freshwater microalgae via central composite design.
Autorzy :
Akış S; Bioengineering Department, Yıldız Technical University, Istanbul, Turkey.
Özçimen D; Bioengineering Department, Yıldız Technical University, Istanbul, Turkey.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 May; Vol. 35 (3), pp. e2801. Date of Electronic Publication: 2019 Mar 18.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Cell Culture Techniques/*methods
Chlorella/*growth & development
Culture Media/*chemistry
Microalgae/*growth & development
Biomass ; Cell Culture Techniques/instrumentation ; Chlorella/metabolism ; Culture Media/metabolism ; Flocculation ; Hydrogen-Ion Concentration ; Microalgae/metabolism
Czasopismo naukowe
Tytuł :
Case study: The characterization and implementation of dielectric spectroscopy (biocapacitance) for process control in a commercial GMP CHO manufacturing process.
Autorzy :
Moore B; Cell Culture Development, Biogen, Research Triangle Park, North Carolina.
Sanford R; Cell Culture Development, Biogen, Research Triangle Park, North Carolina.
Zhang A; Cell Culture Development, Biogen, Research Triangle Park, North Carolina.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 May; Vol. 35 (3), pp. e2782. Date of Electronic Publication: 2019 Feb 14.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
CHO Cells/*metabolism
Cell Culture Techniques/*methods
Dielectric Spectroscopy/*methods
Animals ; Biomass ; Bioreactors ; CHO Cells/cytology ; Cell Culture Techniques/instrumentation ; Cell Proliferation ; Cricetinae ; Cricetulus ; Culture Media/metabolism ; Glucose/metabolism
Czasopismo naukowe
Tytuł :
Fluorescence-based real time monitoring and diagnostics of recombinant Pichia pastoris cultivations in a bioreactor.
Autorzy :
Karakach TK; Halifax, NS, B3H 3Z1.
Dachon A; National Research Council Canada, Montreal, QC, H4P 2R2, Canada.
Choi J; National Research Council Canada, Montreal, QC, H4P 2R2, Canada.
Miguez C; National Research Council Canada, Montreal, QC, H4P 2R2, Canada.
Masson L; National Research Council Canada, Montreal, QC, H4P 2R2, Canada.
Tartakovsky B; National Research Council Canada, Montreal, QC, H4P 2R2, Canada.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Mar; Vol. 35 (2), pp. e2761. Date of Electronic Publication: 2018 Dec 21.
Typ publikacji :
Journal Article
MeSH Terms :
Bioreactors*
Cell Culture Techniques*
Fluorescence*
Pichia/*cytology
Multivariate Analysis ; Time Factors
Czasopismo naukowe
Tytuł :
Automated and enhanced clone screening using a fully automated microtiter plate-based system for suspension cell culture.
Autorzy :
Markert S; Pharmaceutical Biotech Production and Development, Roche Diagnostics GmbH, Penzberg, Germany.
Musmann C; Pharmaceutical Biotech Production and Development, Roche Diagnostics GmbH, Penzberg, Germany.
Hülsmann P; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Munich, Germany.
Joeris K; Pharmaceutical Biotech Production and Development, Roche Diagnostics GmbH, Penzberg, Germany.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Mar; Vol. 35 (2), pp. e2760. Date of Electronic Publication: 2019 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Automation*
Cell Culture Techniques*/instrumentation
High-Throughput Screening Assays*/instrumentation
Animals ; CHO Cells ; Cells, Cultured ; Cricetulus
Czasopismo naukowe
Tytuł :
Anchorage-dependent cell expansion in fiber-shaped microcarrier aggregates.
Autorzy :
Ikeda K; Inst. of Industrial Science, The University of Tokyo, Tokyo, Japan.
Takeuchi S; Inst. of Industrial Science, The University of Tokyo, Tokyo, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Tokyo, Japan.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Mar; Vol. 35 (2), pp. e2755. Date of Electronic Publication: 2018 Dec 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques*
Dextrans/*chemistry
Animals ; Cell Survival ; Cells, Cultured ; Mice
Czasopismo naukowe
Tytuł :
Fabrication of thin-layer matrigel-based constructs for three-dimensional cell culture.
Autorzy :
Ko KR; School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
Tsai MC; School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
Frampton JP; School of Biomedical Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Jan; Vol. 35 (1), pp. e2733. Date of Electronic Publication: 2018 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques/*methods
Collagen/*chemistry
Laminin/*chemistry
Proteoglycans/*chemistry
Asthma/metabolism ; Cells, Cultured ; Drug Combinations ; Extracellular Matrix/chemistry ; Humans ; Hydrogels ; Myocytes, Smooth Muscle/cytology ; Tissue Engineering/methods
Czasopismo naukowe
Tytuł :
Rapid creation system of morphologically and functionally communicative three-dimensional cell-dense tissue by centrifugation.
Autorzy :
Haraguchi Y; Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Matsuura K; Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Kagawa Y; Ogino Memorial Laboratory, Nihon Kohden Corporation, TWIns, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Hasegawa A; Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Kubo H; Ogino Memorial Laboratory, Nihon Kohden Corporation, TWIns, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Shimizu T; Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2018 Nov; Vol. 34 (6), pp. 1447-1453. Date of Electronic Publication: 2018 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques/*methods
Induced Pluripotent Stem Cells/*cytology
Tissue Engineering/*methods
Humans ; Myoblasts/cytology
Czasopismo naukowe
Tytuł :
Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness.
Autorzy :
Scarcelli JJ; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, 01810.
Hone M; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, 01810.
Beal K; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, 01810.
Ortega A; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, 01810.
Figueroa B; Culture Process Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, 01810.
Starkey JA; Analytical Research and Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, 63017.
Anderson K; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, 01810.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2018 May; Vol. 34 (3), pp. 602-612. Date of Electronic Publication: 2018 Jul 01.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Culture Techniques*
Quality Control*
Antibodies, Monoclonal/*biosynthesis
Clone Cells/*cytology
Animals ; Antibodies, Monoclonal/genetics ; CHO Cells ; Cricetulus ; Gene Dosage ; Phenotype ; Tissue Banks
Czasopismo naukowe
Tytuł :
Development and characterization of an automated imaging workflow to generate clonally-derived cell lines for therapeutic proteins.
Autorzy :
Shaw D; Early Stage Cell Culture, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
Yim M; Early Stage Cell Culture, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
Tsukuda J; Early Stage Cell Culture, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
Joly JC; Analytical Development and Quality Control, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
Lin A; Pharma Technical Development Project and Portfolio Management, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
Snedecor B; Early Stage Cell Culture, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
Laird MW; Early Stage Cell Culture, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
Lang SE; Early Stage Cell Culture, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2018 May; Vol. 34 (3), pp. 584-592. Date of Electronic Publication: 2017 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Automation*
Cell Culture Techniques*
Image Processing, Computer-Assisted*
Antibodies, Monoclonal/*biosynthesis
Clone Cells/*cytology
Clone Cells/*metabolism
Recombinant Proteins/*biosynthesis
Animals ; Antibodies, Monoclonal/therapeutic use ; CHO Cells ; Cricetulus ; High-Throughput Screening Assays ; Recombinant Proteins/therapeutic use
Czasopismo naukowe
Tytuł :
Development of generic raman models for a GS-KO CHO platform process.
Autorzy :
Webster TA; Lonza Biologics Inc., 101 International Dr, Portsmouth, NH, 03801.
Hadley BC; Lonza Biologics Inc., 101 International Dr, Portsmouth, NH, 03801.
Hilliard W; Lonza Biologics Inc., 101 International Dr, Portsmouth, NH, 03801.
Jaques C; Lonza Biologics plc, 228 Bath road, Slough, SL14DX.
Mason C; Lonza Biologics Inc., 101 International Dr, Portsmouth, NH, 03801.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2018 May; Vol. 34 (3), pp. 730-737. Date of Electronic Publication: 2018 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Culture Techniques*
Models, Statistical*
Ammonium Compounds/analysis ; Animals ; CHO Cells ; Calibration ; Cells, Cultured ; Cricetulus ; Glucose/analysis ; Glutamic Acid/analysis ; Lactic Acid/analysis ; Software ; Spectrum Analysis, Raman
Czasopismo naukowe

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