Autor: "Bisig, Bettina" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Response and Resistance to Trametinib in MAP2K1-Mutant Triple-Negative Melanoma.
Autorzy:: Krebs FS; Computer-Aided Molecular Engineering, Department of Oncology UNIL-CHUV, University of Lausanne, 1015 Lausanne, Switzerland.; Ludwig Institute for Cancer Research, 1005 Lausanne, Switzerland.
Moura B; Service of Medical Oncology, 1700 Fribourg, Switzerland.
Missiaglia E; Department of Laboratory Medicine and Pathology, Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne University, 1011 Lausanne, Switzerland.; Molecular Modelling Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Aedo-Lopez V; Monash Medical Centre, Clayton, VIC 3168, Australia.
Michielin O; Molecular Modelling Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Service of Medical Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Centre for Personalized Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.; Department of Oncology, Hopitaux Universitaire de Genève, 1205 Geneva, Switzerland.
Tsantoulis P; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.; Department of Oncology, Hopitaux Universitaire de Genève, 1205 Geneva, Switzerland.
Bisig B; Department of Laboratory Medicine and Pathology, Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne University, 1011 Lausanne, Switzerland.
Trimech M; Department of Laboratory Medicine and Pathology, Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne University, 1011 Lausanne, Switzerland.
Zoete V; Computer-Aided Molecular Engineering, Department of Oncology UNIL-CHUV, University of Lausanne, 1015 Lausanne, Switzerland.; Ludwig Institute for Cancer Research, 1005 Lausanne, Switzerland.; Molecular Modelling Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.
Homicsko K; Ludwig Institute for Cancer Research, 1005 Lausanne, Switzerland.; Service of Medical Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Centre for Personalized Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 24; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:: Case Reports
MeSH Terms:: Skin Neoplasms*/genetics
Melanoma*/genetics
Male ; Humans ; Pyridones/therapeutic use ; Pyrimidinones/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Mitogen-Activated Protein Kinase Kinases/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Mutation ; MAP Kinase Kinase 1/genetics

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Skocz do pozycji: 2.

Tytuł:: Postmortem Cardiopulmonary Pathology in Patients with COVID-19 Infection: Single-Center Report of 12 Autopsies from Lausanne, Switzerland.
Autorzy:: Berezowska S; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Lefort K; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Ioannidou K; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Ndiaye DR; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Maison D; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Petrovas C; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Rotman S; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Piazzon N; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Milowich D; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Sala N; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Tsai CY; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Multone E; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
Bochud PY; Department of Medicine, Service of Infectious Diseases, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1011 Lausanne, Switzerland.
Oddo M; Adult Intensive Care Medicine Service, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, 1011 Lausanne, Switzerland.; Medical Direction for Research and Education, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 21, 1011 Lausanne, Switzerland.
Bisig B; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.
de Leval L; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 25, 1011 Lausanne, Switzerland.; Pokaż więcej
Źródło:: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2021 Jul 28; Vol. 11 (8). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji:: Journal Article

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Tytuł:: Recent advances upper gastrointestinal lymphomas: molecular updates and diagnostic implications.
Autorzy:: Foukas PG; Second Department of Pathology, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.
Bisig B; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.
de Leval L; Second Department of Pathology, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.; Pokaż więcej
Źródło:: Histopathology [Histopathology] 2021 Jan; Vol. 78 (1), pp. 187-214.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Gastrointestinal Neoplasms/*diagnosis
Lymphoma/*diagnosis
Upper Gastrointestinal Tract/*pathology
Diagnosis, Differential ; Gastrointestinal Neoplasms/metabolism ; Gastrointestinal Neoplasms/pathology ; Humans ; Immunophenotyping ; Lymphoma/metabolism ; Lymphoma/pathology ; Upper Gastrointestinal Tract/metabolism

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Skocz do pozycji: 4.

Tytuł:: Trametinib Induces the Stabilization of a Dual GNAQ p.Gly48Leu- and FGFR4 p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology.
Autorzy:: Krebs FS; Computer-aided molecular engineering group, Department of Fundamental Oncology, Lausanne University, Ludwig Lausanne Branch, 1066 Epalinges, Switzerland.
Gérard C; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Wicky A; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Aedo-Lopez V; Service of Medical Oncology, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Missiaglia E; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Bisig B; University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Trimech M; University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Michielin O; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.; Service of Medical Oncology, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Homicsko K; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Laboratory of Translational Oncology, EPFL, 1015 Lausanne, Switzerland.
Zoete V; Computer-aided molecular engineering group, Department of Fundamental Oncology, Lausanne University, Ludwig Lausanne Branch, 1066 Epalinges, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 28; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 28.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Mutation*
GTP-Binding Protein alpha Subunits, Gq-G11/*chemistry
Melanoma/*drug therapy
Melanoma/*genetics
Mutant Proteins/*chemistry
Pyridones/*therapeutic use
Pyrimidinones/*therapeutic use
Receptor, Fibroblast Growth Factor, Type 4/*chemistry
Uveal Neoplasms/*drug therapy
Uveal Neoplasms/*genetics
Amino Acid Sequence ; Antineoplastic Agents/therapeutic use ; Female ; GTP-Binding Protein alpha Subunits, Gq-G11/genetics ; GTP-Binding Protein alpha Subunits, Gq-G11/metabolism ; Humans ; Melanoma/metabolism ; Melanoma/pathology ; Middle Aged ; Models, Molecular ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Protein Conformation ; Protein Stability ; Receptor, Fibroblast Growth Factor, Type 4/genetics ; Receptor, Fibroblast Growth Factor, Type 4/metabolism ; Sequence Homology ; Signal Transduction ; Uveal Neoplasms/metabolism ; Uveal Neoplasms/pathology
SCR Disease Name:: Uveal melanoma

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Skocz do pozycji: 5.

Tytuł:: Focal β-catenin mutation identified on formalin-fixed and paraffin-embedded inflammatory hepatocellular adenomas.
Autorzy:: Saldarriaga J; Service of Clinical Pathology, Lausanne University Hospital, Institute of Pathology, Lausanne, Switzerland.
Bisig B; Service of Clinical Pathology, Lausanne University Hospital, Institute of Pathology, Lausanne, Switzerland.
Couchy G; Functional Genomics of Solid Tumors, Université Paris Descartes, Université Paris Diderot, Paris, France.
Castain C; Service de Pathologie, Hôpital Pellegrin, CHU Bordeaux, Bordeaux, France.
Zucman-Rossi J; Functional Genomics of Solid Tumors, Université Paris Descartes, Université Paris Diderot, Paris, France.
Balabaud C; Inserm UMR 1053, Université Bordeaux, Bordeaux, France.
Sempoux C; Service of Clinical Pathology, Lausanne University Hospital, Institute of Pathology, Lausanne, Switzerland.
Bioulac-Sage P; Service de Pathologie, Hôpital Pellegrin, CHU Bordeaux, Bordeaux, France.; Inserm UMR 1053, Université Bordeaux, Bordeaux, France.; Pokaż więcej
Źródło:: Histopathology [Histopathology] 2017 Dec; Vol. 71 (6), pp. 989-993. Date of Electronic Publication: 2017 Oct 06.
Typ publikacji:: Journal Article
MeSH Terms:: Adenoma, Liver Cell/*genetics
Biomarkers, Tumor/*genetics
Liver Neoplasms/*genetics
beta Catenin/*genetics
Adenoma, Liver Cell/pathology ; Adult ; Biomarkers, Tumor/metabolism ; C-Reactive Protein/metabolism ; Cell Transformation, Neoplastic ; Female ; Formaldehyde ; Glutamate-Ammonia Ligase/metabolism ; Humans ; Immunohistochemistry ; Liver Neoplasms/pathology ; Microdissection ; Middle Aged ; Mutation ; Paraffin Embedding ; beta Catenin/metabolism

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Skocz do pozycji: 6.

Tytuł:: Continuous quantification of HER2 expression by microfluidic precision immunofluorescence estimates HER2 gene amplification in breast cancer.
Autorzy:: Dupouy DG; Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Switzerland.
Ciftlik AT; Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Switzerland.; Lunaphore Technologies SA, EPFL Innovation Park-Building C, CH-1015, Lausanne, Switzerland.
Fiche M; Institute of Pathology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, CH-1011 Lausanne, Switzerland.
Heintze D; Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Switzerland.; Lunaphore Technologies SA, EPFL Innovation Park-Building C, CH-1015, Lausanne, Switzerland.
Bisig B; Institute of Pathology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, CH-1011 Lausanne, Switzerland.
de Leval L; Institute of Pathology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, CH-1011 Lausanne, Switzerland.
Gijs MA; Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Switzerland.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Feb 09; Vol. 6, pp. 20277. Date of Electronic Publication: 2016 Feb 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Amplification*
Biomarkers, Tumor/*genetics
Breast Neoplasms/*genetics
Microfluidics/*instrumentation
Microfluidics/*methods
Receptor, ErbB-2/*genetics
Biomarkers, Tumor/metabolism ; Breast Neoplasms/metabolism ; Female ; Fluorescent Antibody Technique ; Humans ; In Situ Hybridization, Fluorescence ; Pilot Projects ; Receptor, ErbB-2/metabolism