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Wyświetlanie 1-20 z 92
Tytuł:
Systems analysis of human responses to an aluminium hydroxide-adsorbed TLR7 agonist (AS37) adjuvanted vaccine reveals a dose-dependent and specific activation of the interferon-mediated antiviral response.
Autorzy:
Siena, Emilio (AUTHOR)
Schiavetti, Francesca (AUTHOR)
Borgogni, Erica (AUTHOR)
Taccone, Marianna (AUTHOR)
Faenzi, Elisa (AUTHOR)
Brazzoli, Michela (AUTHOR)
Aprea, Susanna (AUTHOR)
Bardelli, Monia (AUTHOR)
Volpini, Gianfranco (AUTHOR)
Buricchi, Francesca (AUTHOR)
Sammicheli, Chiara (AUTHOR)
Tavarini, Simona (AUTHOR)
Bechtold, Viviane (AUTHOR)
Blohmke, Christoph J. (AUTHOR) christoph.j.blohmke@gsk.com
Cardamone, Dario (AUTHOR)
De Intinis, Carlo (AUTHOR)
Gonzalez-Lopez, Antonio (AUTHOR)
O'Hagan, Derek T. (AUTHOR)
Nuti, Sandra (AUTHOR)
Seidl, Claudia (AUTHOR)
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Źródło:
Vaccine. Jan2023, Vol. 41 Issue 3, p724-734. 11p.
Czasopismo naukowe
Szczegóły
Tytuł:
Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever.
Autorzy:
Salerno-Gonçalves, Rosângela (AUTHOR)
Fresnay, Stephanie (AUTHOR)
Magder, Laurence (AUTHOR)
Darton, Thomas C. (AUTHOR)
Waddington, Claire S. (AUTHOR)
Blohmke, Christoph J. (AUTHOR)
Angus, Brian (AUTHOR)
Levine, Myron M. (AUTHOR)
Pollard, Andrew J. (AUTHOR)
Sztein, Marcelo B. (AUTHOR)
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Źródło:
Cellular Immunology. Aug2022, Vol. 378, pN.PAG-N.PAG. 1p.
Czasopismo naukowe
Szczegóły
Tytuł:
Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA.
Autorzy:
Tondi, Serena
Clemente, Bruna
Esposito, Carmen
Sammicheli, Chiara
Tavarini, Simona
Martin, Laura B.
Rossi, Omar
Micoli, Francesca
Bartolini, Erika
Brazzoli, Michela
Ulivieri, Cristina
Blohmke, Christoph J.
Schiavetti, Francesca
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Temat:
IMMUNE response
MONONUCLEAR leukocytes
MONOCYTES
SHIGELLA
BACTERIAL cell walls
T cells
EXOSOMES
GRAM-negative bacteria
Źródło:
Frontiers in Cellular & Infection Microbiology; 2/3/2022, Vol. 12, p1-10, 10p
Czasopismo naukowe
Szczegóły
Tytuł:
Vi-Vaccinations Induce Heterogeneous Plasma Cell Responses That Associate With Protection From Typhoid Fever.
Autorzy:
Cross, Deborah L.
Verheul, Marije K.
Leipold, Michael D.
Obermoser, Gerlinde
Jin, Celina
Jones, Elizabeth
Starr, Joshua S.
Mohorianu, Irina
Blohmke, Christoph J.
Maecker, Holden T.
Napolitani, Giorgio
Hill, Jennifer
Pollard, Andrew J.
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Temat:
TYPHOID fever
PLASMA cells
TETANUS vaccines
T helper cells
VACCINATION
Źródło:
Frontiers in Immunology; 12/3/2020, Vol. 11, pN.PAG-N.PAG, 11p
Czasopismo naukowe
Szczegóły
Tytuł:
Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model.
Autorzy:
Gibani MM; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.; Department of Infectious Diseases, Imperial College London, United Kingdom.
Jin C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Shrestha S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Moore M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Norman L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Voysey M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Jones E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Blackwell L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Thomaides-Brears H; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Hill J; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Blohmke CJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Dobinson HC; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Baker P; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Jones C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Campbell D; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Mujadidi YF; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Plested E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
Preciado-Llanes L; Institute for Infection and Global Health, University of Liverpool, United Kingdom.; Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, University of Oxford, United Kingdom.
Napolitani G; Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, University of Oxford, United Kingdom.
Simmons A; Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, University of Oxford, United Kingdom.
Gordon MA; Institute for Infection and Global Health, University of Liverpool, United Kingdom.; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Angus B; Nuffield Department of Medicine, University of Oxford, United Kingdom.
Darton TC; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.
Cerundulo V; Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, University of Oxford, United Kingdom.
Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, United Kingdom.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Oct 20; Vol. 14 (10), pp. e0008783. Date of Electronic Publication: 2020 Oct 20 (Print Publication: 2020).
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Paratyphoid Fever/*immunology
Salmonella paratyphi A/*physiology
Salmonella typhi/*physiology
Typhoid Fever/*immunology
Adolescent ; Adult ; Cross Protection ; Female ; Humans ; Immunity, Humoral ; Male ; Middle Aged ; Paratyphoid Fever/microbiology ; Salmonella paratyphi A/immunology ; Salmonella typhi/immunology ; Typhoid Fever/microbiology ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases.
Autorzy:
Blohmke, Christoph J
Muller, Julius
Gibani, Malick M
Dobinson, Hazel
Shrestha, Sonu
Perinparajah, Soumya
Jin, Celina
Hughes, Harri
Blackwell, Luke
Dongol, Sabina
Karkey, Abhilasha
Schreiber, Fernanda
Pickard, Derek
Basnyat, Buddha
Dougan, Gordon
Baker, Stephen
Pollard, Andrew J
Darton, Thomas C
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Źródło:
EMBO Molecular Medicine; Oct2019, Vol. 11 Issue 10, pN.PAG-N.PAG, 1p
Czasopismo naukowe
Szczegóły
Tytuł:
Salmonella Typhi Bactericidal Antibodies Reduce Disease Severity but Do Not Protect against Typhoid Fever in a Controlled Human Infection Model.
Autorzy:
Juel, Helene B.
Thomaides-Brears, Helena B.
Darton, Thomas C.
Jones, Claire
Jones, Elizabeth
Shrestha, Sonu
Sie, Rebecca
Eustace, Andrew
Galal, Ushma
Kurupati, Prathiba
Van, Tan T.
Thieu, Nga T. V.
Baker, Stephen
Blohmke, Christoph J.
Pollard, Andrew J.
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Temat:
SALMONELLA typhi
IMMUNE response
Źródło:
Frontiers in Immunology; 1/17/2018, p1-N.PAG, 11p
Czasopismo naukowe
Szczegóły
Tytuł:
Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial.
Autorzy:
Jin, Celina
Gibani, Malick M.
Moore, Maria
Juel, Helene B.
Jones, Elizabeth
Meiring, James
Harris, Victoria
Gardner, Jonathan
Nebykova, Anna
Kerridge, Simon A.
Hill, Jennifer
Thomaides-Brears, Helena
Blohmke, Christoph J.
Ly-Mee Yu
Angus, Brian
Pollard, Andrew J.
Yu, Ly-Mee
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Źródło:
Lancet. 12/2/2017, Vol. 390 Issue 10111, p2472-2480. 9p.
Czasopismo naukowe
Szczegóły
Tytuł:
Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of SalmonellaTyphi: a randomised controlled, phase 2b trial
Autorzy:
Jin, Celina
Gibani, Malick M
Moore, Maria
Juel, Helene B
Jones, Elizabeth
Meiring, James
Harris, Victoria
Gardner, Jonathan
Nebykova, Anna
Kerridge, Simon A
Hill, Jennifer
Thomaides-Brears, Helena
Blohmke, Christoph J
Yu, Ly-Mee
Angus, Brian
Pollard, Andrew J
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Źródło:
The Lancet; December 2017, Vol. 390 Issue: 10111 p2472-2480, 9p
Periodyk
Szczegóły
Tytuł:
Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal.
Autorzy:
Darton, Thomas C.
Jones, Claire
Dongol, Sabina
Voysey, Merryn
Blohmke, Christoph J.
Shrestha, Rajendra
Karkey, Abhilasha
Shakya, Mila
Arjyal, Amit
Waddington, Claire S.
Gibani, Malick
Carter, Michael J.
Basnyat, Buddha
Baker, Stephen
Pollard, Andrew J.
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Temat:
IMMUNOGLOBULIN analysis
TYPHOID fever
LYMPHOCYTE receptors
Źródło:
Frontiers in Microbiology; 10/23/2017, p1-13, 13p
Czasopismo naukowe
Szczegóły
Tytuł:
Induction of Cell Cycle and NK Cell Responses by Live-Attenuated Oral Vaccines Against Typhoid Fever.
Autorzy:
Blohmke, Christoph J.
Hill, Jennifer
Darton, Thomas C.
Carvalho-Burger, Matheus
Eustace, Andrew
Jones, Claire
Schreiber, Fernanda
Goodier, Martin R.
Dougan, Gordon
Nakaya, Helder I.
Pollard, Andrew J.
Pokaż więcej
Temat:
IMMUNE response
SALMONELLA typhi
CELL cycle
VACCINATION
Źródło:
Frontiers in Immunology; 10/12/2017, p1-13, 13p
Czasopismo naukowe
Szczegóły
Tytuł:
Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells.
Autorzy:
Salerno-Goncalves, Rosângela
Luo, David
Fresnay, Stephanie
Magder, Laurence
Darton, Thomas C.
Jones, Claire
Waddington, Claire S.
Blohmke, Christoph J.
Angus, Brian
Levine, Myron M.
Pollard, Andrew J.
Sztein, Marcelo B.
Pokaż więcej
Temat:
SALMONELLA enterica serovar Typhi
GASTROINTESTINAL diseases
T cells
THERAPEUTICS
Źródło:
Frontiers in Immunology; 4/6/2017, Vol. 8, p1-13, 13p
Czasopismo naukowe
Szczegóły
Tytuł:
Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia.
Autorzy:
Darton, Thomas C.
Zhou, Liqing
Blohmke, Christoph J.
Jones, Claire
Waddington, Claire S.
Baker, Stephen
Pollard, Andrew J.
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Temat:
BACTEREMIA diagnosis
TYPHOID fever diagnosis
BACTEREMIA
CULTURE media (Biology)
DNA
FEVER
POLYMERASE chain reaction
SALMONELLA
TYPHOID fever
HUMAN research subjects
Źródło:
Journal of Infection; Apr2017, Vol. 74 Issue 4, p358-366, 9p
Czasopismo naukowe
Szczegóły
Tytuł:
Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model.
Autorzy:
Fresnay, Stephanie
McArthur, Monica A.
Magder, Laurence S.
Darton, Thomas C.
Jones, Claire
Waddington, Claire S.
Blohmke, Christoph J.
Angus, Brian
Levine, Myron M.
Pollard, Andrew J.
Sztein, Marcelo B.
Pokaż więcej
Temat:
SALMONELLA
TYPHOID fever
CELLULAR immunity
Źródło:
Frontiers in Immunology; 3/3/2017, Vol. 8, p1-15, 15p
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 92

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