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Wyszukujesz frazę ""Blood Platelets"" wg kryterium: Temat


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Tytuł :
Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and convalescent phase of COVID-19.
Autorzy :
Chao Y; Division of Infection Medicine, Department of Clinical Sciences, Lund, Faculty of Medicine, Lund University, Lund, Sweden.
Rebetz J; Division of Hematology and Transfusion Medicine, Faculty of Medicine, Lund University, Sweden; Clinical Immunology and Transfusion Medicine, Office of Medical Services, Region Skåne, Lund, Sweden.
Bläckberg A; Division of Infection Medicine, Department of Clinical Sciences, Lund, Faculty of Medicine, Lund University, Lund, Sweden.; Skåne University Hospital, Lund, Sweden.
Hovold G; Division of Infection Medicine, Department of Clinical Sciences, Lund, Faculty of Medicine, Lund University, Lund, Sweden.
Sunnerhagen T; Division of Infection Medicine, Department of Clinical Sciences, Lund, Faculty of Medicine, Lund University, Lund, Sweden.; Clinical Microbiology, Office of Medical Services, Region Skåne, Lund, Sweden.
Rasmussen M; Division of Infection Medicine, Department of Clinical Sciences, Lund, Faculty of Medicine, Lund University, Lund, Sweden.; Skåne University Hospital, Lund, Sweden.
Semple JW; Division of Hematology and Transfusion Medicine, Faculty of Medicine, Lund University, Sweden; Clinical Immunology and Transfusion Medicine, Office of Medical Services, Region Skåne, Lund, Sweden.
Shannon O; Division of Infection Medicine, Department of Clinical Sciences, Lund, Faculty of Medicine, Lund University, Lund, Sweden.
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Źródło :
Platelets [Platelets] 2021 Nov 17; Vol. 32 (8), pp. 1092-1102. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Clinical Trial; Journal Article; Video-Audio Media
MeSH Terms :
Blood Platelets*/metabolism
Blood Platelets*/pathology
COVID-19*/blood
COVID-19*/pathology
Convalescence*
Monocytes*/metabolism
Monocytes*/pathology
Neutrophil Activation*
Neutrophils*/metabolism
Neutrophils*/pathology
Platelet Activation*
SARS-CoV-2/*metabolism
Acute Disease ; Adult ; Aged ; Aged, 80 and over ; Female ; Flow Cytometry ; Humans ; Interleukin-10/blood ; Interleukin-6/blood ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Platelet Heterogeneity in Myeloproliferative Neoplasms.
Autorzy :
Thomas S; Department of Oncology and Metabolism, University of Sheffield and Department of Haematology, Royal Hallamshire Hospital, United Kingdom (S.T.).
Krishnan A; Department of Pathology, Stanford University School of Medicine, CA (A.K.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Nov; Vol. 41 (11), pp. 2661-2670. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Platelet Activation*/drug effects
Thrombopoiesis*/drug effects
Blood Platelets/*metabolism
Myeloproliferative Disorders/*blood
Animals ; Antineoplastic Agents/therapeutic use ; Blood Coagulation ; Blood Platelets/drug effects ; Blood Platelets/pathology ; Humans ; Molecular Targeted Therapy ; Myeloproliferative Disorders/drug therapy ; Myeloproliferative Disorders/genetics ; Myeloproliferative Disorders/pathology ; Phenotype ; Platelet Aggregation Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Soluble thrombomodulin ameliorates aberrant hemostasis after rewarming in a rat accidental hypothermia model.
Autorzy :
Takauji S; Department of Emergency Medicine, Asahikawa Medical University Hospital, Japan. Electronic address: .
Tanaka H; Division of Tumor Pathology, Department of Pathology, Asahikawa Medical University, Japan.
Hayakawa M; Department of Emergency Medicine, Hokkaido University Hospital, Japan.
Horioka K; Department of Legal Medicine, International University of Health and Welfare, Japan; Department of Oncology-Pathology, Karolinska Institutet, Japan.
Isozaki S; Gastroenterology and Endoscopy, Division of Metabolism and Biosystemic Science, Gastroenterology, and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Japan.
Konishi H; Department of Gastroenterology and Advanced Medical Sciences, Asahikawa Medical University, Japan.
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jan 08; Vol. 587, pp. 1-8. Date of Electronic Publication: 2021 Nov 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticoagulants/*pharmacology
Blood Platelets/*drug effects
Fibrin Fibrinogen Degradation Products/*metabolism
Hypothermia/*complications
Thrombomodulin/*administration & dosage
Thrombosis/*prevention & control
Animals ; Biomarkers/metabolism ; Blood Platelets/metabolism ; Blood Platelets/pathology ; Disease Models, Animal ; Fibrin/chemistry ; Fibrin/metabolism ; Hypothermia/blood ; Hypothermia/physiopathology ; Kidney Glomerulus/blood supply ; Kidney Glomerulus/drug effects ; Kidney Glomerulus/metabolism ; Kidney Glomerulus/pathology ; Male ; Platelet Activation/drug effects ; Rats ; Rats, Wistar ; Recombinant Proteins/pharmacology ; Rewarming/adverse effects ; Solubility ; Spleen/blood supply ; Spleen/drug effects ; Spleen/metabolism ; Spleen/pathology ; Thrombosis/blood ; Thrombosis/etiology ; Thrombosis/physiopathology
Czasopismo naukowe
Tytuł :
Caught at the Scene of the Crime: Platelets and Neutrophils Are Conspirators in Thrombosis.
Autorzy :
Moon MJ; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia (M.J.M., J.D.M., K.P.).; Baker Department of Cardiometabolic Health, University of Melbourne, Victoria, Australia (M.J.M., J.D.M., K.P.).
McFadyen JD; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia (M.J.M., J.D.M., K.P.).; Baker Department of Cardiometabolic Health, University of Melbourne, Victoria, Australia (M.J.M., J.D.M., K.P.).; Department of Clinical Hematology (J.D.M.), The Alfred Hospital, Melbourne, Victoria, Australia.; Departments of Medicine (J.D.M., K.P.), Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Peter K; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia (M.J.M., J.D.M., K.P.).; Baker Department of Cardiometabolic Health, University of Melbourne, Victoria, Australia (M.J.M., J.D.M., K.P.).; Department of Cardiology (K.P.), The Alfred Hospital, Melbourne, Victoria, Australia.; Departments of Medicine (J.D.M., K.P.), Central Clinical School, Monash University, Melbourne, Victoria, Australia.; Immunology (K.P.), Central Clinical School, Monash University, Melbourne, Victoria, Australia.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2022 Jan; Vol. 42 (1), pp. 63-66. Date of Electronic Publication: 2021 Dec 02.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Blood Platelets*
Thrombosis*
Crime ; Humans ; Neutrophils ; Platelet Activation
Raport
Tytuł :
Prothrombotic Phenotype in COVID-19: Focus on Platelets.
Autorzy :
Barale C; Department of Clinical and Biological Sciences, Turin University, 10043 Orbassano, Turin, Italy.
Melchionda E; Department of Clinical and Biological Sciences, Turin University, 10043 Orbassano, Turin, Italy.
Morotti A; Department of Clinical and Biological Sciences, Turin University, 10043 Orbassano, Turin, Italy.
Russo I; Department of Clinical and Biological Sciences, Turin University, 10043 Orbassano, Turin, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 20; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Blood Platelets/*physiology
COVID-19/*blood
Thrombosis/*pathology
Blood Coagulation ; Blood Coagulation Disorders/etiology ; Blood Platelets/metabolism ; Blood Platelets/virology ; COVID-19/metabolism ; Cytokine Release Syndrome ; Endothelial Cells/pathology ; Fibrin Fibrinogen Degradation Products ; Hemostasis ; Humans ; Inflammation ; Phenotype ; Platelet Activation/physiology ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity ; Thrombocytopenia/metabolism ; Thrombosis/metabolism ; Thrombosis/virology
Czasopismo naukowe
Tytuł :
Platelet GPVI (Glycoprotein VI) and Thrombotic Complications in the Venous System.
Autorzy :
Perrella G; Department of Biochemistry, CARIM, Maastricht University, The Netherlands (G.P., M.N., J.W.M.H.).; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, United Kingdom (G.P., S.P.W.).
Nagy M; Department of Biochemistry, CARIM, Maastricht University, The Netherlands (G.P., M.N., J.W.M.H.).
Watson SP; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, United Kingdom (G.P., S.P.W.).; COMPARE, Universities of Birmingham and Nottingham, The Midlands, United Kingdom (S.P.W.).
Heemskerk JWM; Department of Biochemistry, CARIM, Maastricht University, The Netherlands (G.P., M.N., J.W.M.H.).; Now with Synapse Research Institute, Maastricht, the Netherlands (J.W.M.H.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Nov; Vol. 41 (11), pp. 2681-2692. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Blood Coagulation*/drug effects
Platelet Activation*/drug effects
Blood Platelets/*metabolism
Inflammation/*metabolism
Platelet Membrane Glycoproteins/*metabolism
Venous Thromboembolism/*metabolism
Venous Thrombosis/*metabolism
Animals ; Anti-Inflammatory Agents/therapeutic use ; Blood Platelets/drug effects ; Blood Platelets/pathology ; Fibrinolytic Agents/therapeutic use ; Humans ; Inflammation/blood ; Inflammation/drug therapy ; Inflammation/pathology ; Inflammation Mediators/blood ; Ligands ; Platelet Aggregation Inhibitors/therapeutic use ; Platelet Membrane Glycoproteins/antagonists & inhibitors ; Signal Transduction ; Venous Thromboembolism/blood ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/pathology ; Venous Thrombosis/blood ; Venous Thrombosis/drug therapy ; Venous Thrombosis/pathology
Czasopismo naukowe
Tytuł :
Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): Targeting Pathomechanisms with Bruton Tyrosine Kinase Inhibitors.
Autorzy :
von Hundelshausen P; Institute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Lorenz R; Institute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany.
Siess W; Institute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Weber C; Institute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, The Netherlands.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
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Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2021 Nov; Vol. 121 (11), pp. 1395-1399. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Agammaglobulinaemia Tyrosine Kinase/*antagonists & inhibitors
Blood Platelets/*drug effects
COVID-19 Vaccines/*adverse effects
Platelet Activation/*drug effects
Protein Kinase Inhibitors/*therapeutic use
Purpura, Thrombocytopenic, Idiopathic/*drug therapy
Vaccination/*adverse effects
Agammaglobulinaemia Tyrosine Kinase/metabolism ; Animals ; Autoantibodies/blood ; Blood Platelets/enzymology ; Blood Platelets/immunology ; COVID-19 Vaccines/administration & dosage ; ChAdOx1 nCoV-19 ; Humans ; Molecular Targeted Therapy ; Platelet Factor 4/immunology ; Purpura, Thrombocytopenic, Idiopathic/blood ; Purpura, Thrombocytopenic, Idiopathic/enzymology ; Purpura, Thrombocytopenic, Idiopathic/immunology ; Receptors, IgG/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
What a Family Doctor Should Know about Incidental Finding of High Mean Platelet Volume, Metabolic Syndrome, and Pre-diabetes.
Autorzy :
Braester A; Department of Hematology Galilee Medical Center, Nahariya, Israel.; Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Shturman A; Department of Hematology Galilee Medical Center, Nahariya, Israel.; Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Raviv B; Department of Hematology Galilee Medical Center, Nahariya, Israel.; Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Dorosinsky L; Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Rosental E; Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Atar S; Department of Hematology Galilee Medical Center, Nahariya, Israel.; Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
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Źródło :
The Israel Medical Association journal : IMAJ [Isr Med Assoc J] 2021 Nov; Vol. 23 (11), pp. 699-702.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets*/pathology
Blood Platelets*/physiology
Metabolic Syndrome*/blood
Metabolic Syndrome*/diagnosis
Prediabetic State*/blood
Prediabetic State*/diagnosis
Mean Platelet Volume/*methods
Platelet Activation/*physiology
Asymptomatic Diseases ; Cardiometabolic Risk Factors ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Incidental Findings ; Male ; Middle Aged ; Physicians, Family
Czasopismo naukowe
Tytuł :
Improve the precision of platelet spectrum quantitative analysis based on "M+N" theory.
Autorzy :
Li G; Tianjin University, State Key Laboratory of Precision Measurement Technology and Instruments, China. Electronic address: .
Wang D; Tianjin University, State Key Laboratory of Precision Measurement Technology and Instruments, China. Electronic address: .
Zhao J; Tianjin University of Traditional Chinese Medicine, China.
Zhou M; East China Normal University, China. Electronic address: .
Wang K; Tianjin University, State Key Laboratory of Precision Measurement Technology and Instruments, China. Electronic address: .
Wu S; Tianjin First Central Hospital, China.
Lin L; Tianjin University, State Key Laboratory of Precision Measurement Technology and Instruments, China. Electronic address: .
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Źródło :
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2022 Jan 05; Vol. 264, pp. 120291. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets*
Humans ; Linear Models ; Spectrum Analysis
Czasopismo naukowe
Tytuł :
Whole blood platelet impedance aggregometry with the ROTEM platelet device: comparison of 2 anticoagulants and storage times for the establishment of canine reference intervals.
Autorzy :
Heimgartner LM; Division of Emergency and Critical Care Medicine, Department of Small Animals, Vetsuisse Faculty of the University of Zurich, Zurich, Switzerland.
Stirn M; Clinical Laboratory, Department for Clinical Diagnostics and Services, Vetsuisse Faculty of the University of Zurich, Zurich, Switzerland.
Kutter APN; Section of Anaesthesiology, Department for Clinical Diagnostics and Services, Vetsuisse Faculty of the University of Zurich, Zurich, Switzerland.
Sigrist NE; Division of Emergency and Critical Care Medicine, Department of Small Animals, Vetsuisse Faculty of the University of Zurich, Zurich, Switzerland.
Jud Schefer R; Division of Emergency and Critical Care Medicine, Department of Small Animals, Vetsuisse Faculty of the University of Zurich, Zurich, Switzerland.
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Źródło :
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2022 Jan; Vol. 34 (1), pp. 15-22. Date of Electronic Publication: 2021 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Anticoagulants*/pharmacology
Blood Platelets*
Animals ; Diagnostic Tests, Routine ; Dogs ; Electric Impedance ; Pilot Projects
Czasopismo naukowe
Tytuł :
Platelet-dependent signaling and Low Molecular Weight Protein Tyrosine Phosphatase expression promote aggressive phenotypic changes in gastrointestinal cancer cells.
Autorzy :
Faria AVS; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, NL-3000 CA Rotterdam, the Netherlands; Department of Biochemistry and Tissue Biology, University of Campinas, UNICAMP, Campinas, SP 13083-862, Brazil.
Yu B; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, NL-3000 CA Rotterdam, the Netherlands.
Mommersteeg M; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, NL-3000 CA Rotterdam, the Netherlands.
de Souza-Oliveira PF; Department of Biochemistry and Tissue Biology, University of Campinas, UNICAMP, Campinas, SP 13083-862, Brazil.
Andrade SS; PlateInnove Biotechnology, 13414-018 Piracicaba, SP, Brazil.
Spaander MCW; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, NL-3000 CA Rotterdam, the Netherlands.
de Maat MPM; Department of Hematology, Erasmus University Medical Center Rotterdam, NL-3000 CA Rotterdam, the Netherlands.
Peppelenbosch MP; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, NL-3000 CA Rotterdam, the Netherlands.
Ferreira-Halder CV; Department of Biochemistry and Tissue Biology, University of Campinas, UNICAMP, Campinas, SP 13083-862, Brazil. Electronic address: .
Fuhler GM; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, NL-3000 CA Rotterdam, the Netherlands. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Jan 01; Vol. 1868 (1), pp. 166280. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets/*metabolism
Carcinogenesis/*genetics
Gastrointestinal Neoplasms/*genetics
Protein Tyrosine Phosphatases/*genetics
Proto-Oncogene Proteins/*genetics
Blood Platelets/pathology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Coculture Techniques ; Female ; Gastrointestinal Neoplasms/pathology ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Male ; Molecular Weight ; Neoplasm Metastasis ; Signal Transduction/genetics ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules.
Autorzy :
Marcoux G; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Laroche A; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Hasse S; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Bellio M; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Mbarik M; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Tamagne M; Institut Mondor de Recherche Biomédicale (IMRB), University Paris Est Créteil, INSERM, Créteil, France.; Etablissement Français du Sang, Ivry sur Seine, France.; Laboratory of Excellence GR-Ex, Paris, France.
Allaeys I; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Zufferey A; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Lévesque T; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Rebetz J; Division of Hematology and Transfusion Medicine, Lund University, Lund, Sweden.
Karakeussian-Rimbaud A; Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Canadian Donation and Transplantation Research Program, Edmonton, AB, Canada.
Turgeon J; Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Canadian Donation and Transplantation Research Program, Edmonton, AB, Canada.
Bourgoin SG; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.
Hamzeh-Cognasse H; Université de Lyon, Université Jean Monnet, INSERM U1059, Saint-Etienne, France.
Cognasse F; Université de Lyon, Université Jean Monnet, INSERM U1059, Saint-Etienne, France.; Établissement Français du Sang Auvergne-Rhône-Alpes, Saint-Etienne, France.
Kapur R; Sanquin Research, Department of Experimental Immunohematology, Amsterdam and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Semple JW; Division of Hematology and Transfusion Medicine, Lund University, Lund, Sweden.; Departments of Pharmacology and Medicine, University of Toronto, Toronto, ON, Canada.
Hébert MJ; Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Canadian Donation and Transplantation Research Program, Edmonton, AB, Canada.
Pirenne F; Institut Mondor de Recherche Biomédicale (IMRB), University Paris Est Créteil, INSERM, Créteil, France.; Etablissement Français du Sang, Ivry sur Seine, France.; Laboratory of Excellence GR-Ex, Paris, France.
Overkleeft HS; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden, The Netherlands; and.
Florea BI; Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden, The Netherlands; and.
Dieude M; Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Canadian Donation and Transplantation Research Program, Edmonton, AB, Canada.; Département Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada.
Vingert B; Institut Mondor de Recherche Biomédicale (IMRB), University Paris Est Créteil, INSERM, Créteil, France.; Etablissement Français du Sang, Ivry sur Seine, France.; Laboratory of Excellence GR-Ex, Paris, France.
Boilard E; Centre de Recherche, Centre Hospitalier Universitaire de Québec-Université Laval, Québec, QC, Canada.; Centre de Recherche Arthrite, Faculté de Médecine de l'Université Laval, Québec, QC, Canada.; Canadian Donation and Transplantation Research Program, Edmonton, AB, Canada.
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Źródło :
Blood [Blood] 2021 Dec 23; Vol. 138 (25), pp. 2607-2620.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets/*immunology
Extracellular Vesicles/*immunology
Histocompatibility Antigens Class I/*immunology
Proteasome Endopeptidase Complex/*immunology
Animals ; Antigen Presentation ; Blood Platelets/chemistry ; Extracellular Vesicles/chemistry ; Histocompatibility Antigens Class I/analysis ; Humans ; Mice ; Mice, Inbred C57BL ; Proteasome Endopeptidase Complex/analysis
Czasopismo naukowe
Tytuł :
Ablation of collagen VI leads to the release of platelets with altered function.
Autorzy :
Abbonante V; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Laboratory of Biochemistry-Biotechnology and Advanced Diagnostics, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy.
Gruppi C; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Laboratory of Biochemistry-Biotechnology and Advanced Diagnostics, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy.
Battiston M; Stem Cell Unit, Centro di Riferimento Oncologico di Aviano, Istituto di Ricovero e Cura a Carattere Scientifico, Aviano, Italy.
Zulian A; Department of Biomedical Sciences and Consiglio Nazionale delle Ricerche, Neuroscience Institute, University of Padova, Padova, Italy.
Di Buduo CA; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Laboratory of Biochemistry-Biotechnology and Advanced Diagnostics, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy.
Chrisam M; Department of Molecular Medicine, University of Padova, Padova, Italy.
Sereni L; Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituto di Ricovero e Cura a Carattere Scientifico, San Raffaele Scientific Institute, Milan, Italy.
Laurent PA; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Laboratory of Biochemistry-Biotechnology and Advanced Diagnostics, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy.
Semplicini C; Department of Neurosciences, University of Padova, Padova, Italy.
Lombardi E; Stem Cell Unit, Centro di Riferimento Oncologico di Aviano, Istituto di Ricovero e Cura a Carattere Scientifico, Aviano, Italy.
Mazzucato M; Stem Cell Unit, Centro di Riferimento Oncologico di Aviano, Istituto di Ricovero e Cura a Carattere Scientifico, Aviano, Italy.
Moccia F; Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Petronilli V; Department of Biomedical Sciences and Consiglio Nazionale delle Ricerche, Neuroscience Institute, University of Padova, Padova, Italy.
Villa A; Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituto di Ricovero e Cura a Carattere Scientifico, San Raffaele Scientific Institute, Milan, Italy.; Milan Unit, Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Milan, Italy.
Bello L; Department of Neurosciences, University of Padova, Padova, Italy.
Pegoraro E; Department of Neurosciences, University of Padova, Padova, Italy.
Bernardi P; Department of Biomedical Sciences and Consiglio Nazionale delle Ricerche, Neuroscience Institute, University of Padova, Padova, Italy.
Braghetta P; Department of Molecular Medicine, University of Padova, Padova, Italy.
De Marco L; Stem Cell Unit, Centro di Riferimento Oncologico di Aviano, Istituto di Ricovero e Cura a Carattere Scientifico, Aviano, Italy.; Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, CA; and.
Bonaldo P; Department of Molecular Medicine, University of Padova, Padova, Italy.
Balduini A; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Laboratory of Biochemistry-Biotechnology and Advanced Diagnostics, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy.; Department of Biomedical Engineering, Tufts University, Medford, MA.
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Źródło :
Blood advances [Blood Adv] 2021 Dec 14; Vol. 5 (23), pp. 5150-5163.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets*/metabolism
Calcium Signaling*
Animals ; Collagen ; Humans ; Megakaryocytes/metabolism ; Mice ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism
Czasopismo naukowe
Tytuł :
AVEXIS technology identifies novel platelet-leukocyte binding partners including CD148-CD300a.
Autorzy :
Barroso R; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK; and.; Centre of Membrane Proteins and Receptors, Universities of Birmingham and Nottingham, The Midlands, Birmingham, UK.
Bicknell R; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK; and.; Centre of Membrane Proteins and Receptors, Universities of Birmingham and Nottingham, The Midlands, Birmingham, UK.
Rainger GE; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK; and.
Watson SP; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK; and.; Centre of Membrane Proteins and Receptors, Universities of Birmingham and Nottingham, The Midlands, Birmingham, UK.
Sun Y; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK; and.; Centre of Membrane Proteins and Receptors, Universities of Birmingham and Nottingham, The Midlands, Birmingham, UK.
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Źródło :
Blood advances [Blood Adv] 2021 Dec 14; Vol. 5 (23), pp. 5016-5019.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets*
Leukocytes*
Phagocytosis ; Technology
Czasopismo naukowe
Tytuł :
Characterization and Chromatographic Isolation of Platelet Extracellular Vesicles from Human Platelet Lysates for Applications in Neuroregenerative Medicine.
Autorzy :
Nyam-Erdene A; International PhD Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 101, Taiwan.
Nebie O; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Delila L; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Buée L; Université de Lille, Inserm U1172, CHU-Lille, Lille Neuroscience & Cognition, Lille 59000, France.; Alzheimer & Tauopathies, Labex DISTALZ, Lille 59000, France.; NeuroTMULille International Laboratory, Université de Lille, Lille 59000, France.
Devos D; Université de Lille, Inserm U1172, CHU-Lille, Lille Neuroscience & Cognition, Lille 59000, France.; NeuroTMULille International Laboratory, Université de Lille, Lille 59000, France.
Chou SY; Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.; NeuroTMULille International Laboratory, Taipei Medical University, Taipei 101, Taiwan.
Blum D; Université de Lille, Inserm U1172, CHU-Lille, Lille Neuroscience & Cognition, Lille 59000, France.; Alzheimer & Tauopathies, Labex DISTALZ, Lille 59000, France.; NeuroTMULille International Laboratory, Université de Lille, Lille 59000, France.
Burnouf T; International PhD Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 101, Taiwan.; Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.; NeuroTMULille International Laboratory, Taipei Medical University, Taipei 101, Taiwan.; International PhD Program in Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Brain and Consciousness Research Centre, TMU Shuang Ho Hospital, New Taipei City 106, Taiwan.
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Źródło :
ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2021 Dec 13; Vol. 7 (12), pp. 5823-5835. Date of Electronic Publication: 2021 Nov 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets*
Extracellular Vesicles*
Cell Proliferation ; Chromatography ; Humans
Czasopismo naukowe
Tytuł :
P2Y 12 Inhibition in Murine Myocarditis Results in Reduced Platelet Infiltration and Preserved Ejection Fraction.
Autorzy :
Schmidt SN; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Reichardt W; University Medical Center Freiburg, Department of Radiology-Medical Physics, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; German Consortium for Translational Cancer Research (DKTK), 69120 Heidelberg, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Kaufmann BA; Department of Cardiology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.
Wadle C; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
von Elverfeldt D; University Medical Center Freiburg, Department of Radiology-Medical Physics, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Stachon P; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Medical Center Mannheim, Department of Cardiology, Medical Faculty Mannheim, Haemostaseology and Medical Intensive Care University Heidelberg University, 68167 Mannheim, Germany.
Hilgendorf I; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Wolf D; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Heidt T; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Duerschmied D; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Medical Center Mannheim, Department of Cardiology, Medical Faculty Mannheim, Haemostaseology and Medical Intensive Care University Heidelberg University, 68167 Mannheim, Germany.
Peter K; Baker Heart & Diabetes Institute, Melbourne, VIC 3004, Australia.
Bode C; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
von Zur Mühlen C; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Maier A; Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
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Źródło :
Cells [Cells] 2021 Dec 04; Vol. 10 (12). Date of Electronic Publication: 2021 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets/*metabolism
Myocarditis/*pathology
Myocarditis/*physiopathology
Receptors, Purinergic P2Y12/*metabolism
Stroke Volume/*physiology
Animals ; Binding Sites ; Blood Platelets/drug effects ; Heart Failure/complications ; Heart Failure/pathology ; Heart Failure/physiopathology ; Inflammation/pathology ; Ligands ; Male ; Mice, Inbred BALB C ; Microbubbles ; Myocarditis/diagnosis ; Myocarditis/diagnostic imaging ; Myocardium/pathology ; Platelet Aggregation/drug effects ; Prasugrel Hydrochloride/pharmacology ; Stroke Volume/drug effects ; Swine
Czasopismo naukowe
Tytuł :
Combined effects of plasma von Willebrand factor and platelet measures on the risk of incident venous thromboembolism.
Autorzy :
Edvardsen MS; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.
Hansen ES; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.
Hindberg K; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.
Morelli VM; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.
Ueland T; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.; Research Institute of Internal Medicine and.
Aukrust P; Research Institute of Internal Medicine and.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, Oslo, Norway; and.
Brækkan SK; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.; Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway.
Evensen LH; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.
Hansen JB; Department of Clinical Medicine, Thrombosis Research Center, UiT-The Arctic University of Norway, Tromsø, Norway.; Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway.
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Źródło :
Blood [Blood] 2021 Dec 02; Vol. 138 (22), pp. 2269-2277.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets/*pathology
Venous Thromboembolism/*etiology
von Willebrand Factor/*analysis
Adult ; Aged ; Blood Platelets/cytology ; Case-Control Studies ; Female ; Humans ; Incidence ; Male ; Mean Platelet Volume ; Middle Aged ; Platelet Count ; Risk Factors ; Venous Thromboembolism/blood ; Venous Thromboembolism/diagnosis
Czasopismo naukowe
Tytuł :
A platelet-derived hydrogel improves neovascularisation in full thickness wounds.
Autorzy :
Rahman MM; Skin Bioengineering Laboratory, Victorian Adult Burns Service, Alfred Health, 89 Commercial Road, Melbourne, Vic, Australia; Department of Surgery, Monash University, 99 Commercial Road, Melbourne, Vic, Australia.
Garcia N; Skin Bioengineering Laboratory, Victorian Adult Burns Service, Alfred Health, 89 Commercial Road, Melbourne, Vic, Australia; Department of Surgery, Monash University, 99 Commercial Road, Melbourne, Vic, Australia.
Loh YS; Australian Red Cross Lifeblood,, Alexandria, NSW, Australia.
Marks DC; Australian Red Cross Lifeblood,, Alexandria, NSW, Australia; Sydney Medical School, University of Sydney, Camperdown, Australia.
Banakh I; Skin Bioengineering Laboratory, Victorian Adult Burns Service, Alfred Health, 89 Commercial Road, Melbourne, Vic, Australia; Department of Surgery, Monash University, 99 Commercial Road, Melbourne, Vic, Australia.
Jagadeesan P; Material Materials Science and Engineering, Monash University, 22 Alliance Lane, Clayton, Vic, Australia.
Cameron NR; Material Materials Science and Engineering, Monash University, 22 Alliance Lane, Clayton, Vic, Australia.
Yung-Chih C; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Australia.
Costa M; Australian Red Cross Lifeblood,, Alexandria, NSW, Australia.
Peter K; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Australia.
Cleland H; Skin Bioengineering Laboratory, Victorian Adult Burns Service, Alfred Health, 89 Commercial Road, Melbourne, Vic, Australia; Department of Surgery, Monash University, 99 Commercial Road, Melbourne, Vic, Australia.
Akbarzadeh S; Skin Bioengineering Laboratory, Victorian Adult Burns Service, Alfred Health, 89 Commercial Road, Melbourne, Vic, Australia; Department of Surgery, Monash University, 99 Commercial Road, Melbourne, Vic, Australia. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2021 Dec; Vol. 136, pp. 199-209. Date of Electronic Publication: 2021 Sep 26.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets*
Hydrogels*/pharmacology
Animals ; Becaplermin ; Epidermal Growth Factor ; Mice ; Wound Healing
Czasopismo naukowe
Tytuł :
Clinical course, management, and platelet activity assessment of splanchnic VITT: A case report.
Autorzy :
Corica B; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Cacciani A; Azienda Policlinico Umberto I, Rome, Italy.
Cangemi R; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Visentini M; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Recchia F; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Grillo R; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Vano M; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Sperduti N; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Cincione A; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Buoninfante G; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Pulcinelli F; Department of Experimental Medicine, Sapienza - University of Rome, Rome, Italy.
Chistolini A; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
De Santis A; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Flego D; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Romiti GF; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
Basili S; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy. Electronic address: .
Stefanini L; Department of Translational and Precision Medicine, Sapienza - University of Rome, Rome, Italy.
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Źródło :
Thrombosis research [Thromb Res] 2021 Dec; Vol. 208, pp. 14-17. Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Blood Platelets*
Platelet Factor 4*
Humans
Raport

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