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Tytuł :
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome.
Autorzy :
Xie SC; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Metcalfe RD; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Mizutani H; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139.
Puhalovich T; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Hanssen E; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.; Ian Holmes Imaging Centre, Bio21 Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Morton CJ; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Du Y; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Dogovski C; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Huang SC; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139.
Ciavarri J; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139.
Hales P; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139.
Griffin RJ; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139.
Cohen LH; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139.
Chuang BC; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139.
Wittlin S; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.; University of Basel, 4003 Basel, Switzerland.
Deni I; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY 10032.
Yeo T; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY 10032.
Ward KE; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY 10032.
Barry DC; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Liu B; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Gillett DL; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Crespo-Fernandez BF; Global Health Pharma Research Unit, GSK, 28760 Madrid, Spain.
Ottilie S; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Mittal N; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Churchyard A; Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Ferguson D; Department of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, San Antonio, TX 78249.
Aguiar ACC; São Carlos Institute of Physics, University of São Paulo, São Carlos 13563-120, Brazil.
Guido RVC; São Carlos Institute of Physics, University of São Paulo, São Carlos 13563-120, Brazil.
Baum J; Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Hanson KK; Department of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, San Antonio, TX 78249.
Winzeler EA; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Gamo FJ; Global Health Pharma Research Unit, GSK, 28760 Madrid, Spain.
Fidock DA; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY 10032.; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032.
Baud D; Drug Discovery, Medicines for Malaria Venture, 1215 Geneva 15, Switzerland.
Parker MW; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.; Structural Biology, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
Brand S; Drug Discovery, Medicines for Malaria Venture, 1215 Geneva 15, Switzerland.
Dick LR; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.; Seofon Consulting, Natick, MA 01760.
Griffin MDW; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Gould AE; Discovery Strategy and Operations, Takeda Pharmaceuticals International Co., Cambridge, MA 02139; .
Tilley L; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3010, Australia; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 28; Vol. 118 (39).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Boron Compounds/*pharmacology
Malaria, Falciparum/*drug therapy
Plasmodium falciparum/*drug effects
Proteasome Endopeptidase Complex/*chemistry
Proteasome Inhibitors/*pharmacology
Administration, Oral ; Animals ; Boron Compounds/administration & dosage ; Boron Compounds/chemistry ; Catalytic Domain ; Humans ; Malaria, Falciparum/enzymology ; Malaria, Falciparum/parasitology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Models, Molecular ; Plasmodium falciparum/enzymology ; Proteasome Inhibitors/administration & dosage ; Proteasome Inhibitors/chemistry
Czasopismo naukowe
Tytuł :
Creating Quantum Emitters in Hexagonal Boron Nitride Deterministically on Chip-Compatible Substrates.
Autorzy :
Xu X; School of Materials Engineering, Purdue University, West Lafayette, Indiana 47906, United States.
Martin ZO; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47906, United States.
Sychev D; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47906, United States.
Lagutchev AS; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47906, United States.
Chen YP; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47906, United States.; Department of Physics and Astronomy, Purdue University, West Lafayette, Indiana 47906, United States.; Department of Physics and Astronomy, Aarhus University, Aarhus 8000, Denmark.
Taniguchi T; National Institute for Materials Science, Tsukuba, Ibaraki 305-0047, Japan.
Watanabe K; National Institute for Materials Science, Tsukuba, Ibaraki 305-0047, Japan.
Shalaev VM; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47906, United States.
Boltasseva A; School of Materials Engineering, Purdue University, West Lafayette, Indiana 47906, United States.; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47906, United States.
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Źródło :
Nano letters [Nano Lett] 2021 Oct 13; Vol. 21 (19), pp. 8182-8189. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Boron Compounds*
Silicon Dioxide*
Czasopismo naukowe
Tytuł :
Two birds with one stone: A highly sensitive near-infrared BODIPY-based fluorescent probe for the simultaneous detection of Fe in vivo.
Autorzy :
Xu W; Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin 300071, China.
Wu P; Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin 300071, China.
Li X; Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin 300071, China.
Liu S; Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin 300071, China.
Feng L; Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin 300071, China.
Xiong H; Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin 300071, China. Electronic address: .
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Źródło :
Talanta [Talanta] 2021 Oct 01; Vol. 233, pp. 122601. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Boron Compounds*
Fluorescent Dyes*
Fluorescence ; Lysosomes
Czasopismo naukowe
Tytuł :
New β-diketone-boron difluoride based near-infrared fluorescent probes for polarity detection.
Autorzy :
Ma Q; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
Zhang Y; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
Jiao Y; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
Zhang T; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
Chu Q; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
Xiao H; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
Zhou Z; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
Liu Y; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, P. R. China. .
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Źródło :
The Analyst [Analyst] 2021 Sep 27; Vol. 146 (19), pp. 5873-5879. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article
MeSH Terms :
Boron Compounds*
Fluorescent Dyes*
Solvents ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
Thermal conductivity of random polycrystalline BC 3 nanosheets: A step towards realistic simulation of 2D structures.
Autorzy :
Fooladpanjeh S; Department of Mechanical Engineering, Shahrood Branch, Islamic Azad University, Shahrood, Iran.
Yousefi F; Department of Physics, University of Zanjan, Zanjan, 45195-313, Iran.
Molaei F; Mining and Geological Engineering Department, The University of Arizona, Arizona, USA.
Zarghami Dehaghani M; Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran.
Sajadi SM; Department of Nutrition, Cihan University-Erbil, Kurdistan Region, Iraq; Department of Phytochemistry, SRC, Soran University, KRG, Iraq.
Abida O; College of Engineering and Technology, American University of the Middle East, Kuwait.
Habibzadeh S; Department of Chemical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.
Hamed Mashhadzadeh A; Mechanical and Aerospace Engineering, School of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan, 010000, Kazakhstan. Electronic address: .
Saeb MR; Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran.
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Źródło :
Journal of molecular graphics & modelling [J Mol Graph Model] 2021 Sep; Vol. 107, pp. 107977. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Boron Compounds*
Molecular Dynamics Simulation*
Temperature ; Thermal Conductivity
Czasopismo naukowe
Tytuł :
Viewpoint Regarding "Singlet Fission Mediated Photophysics of BODIPY Dimers".
Autorzy :
Montero R; SGIKER Laser Facility, Universidad del País Vasco, UPV/EHU, Apartado 644, 48080 Bilbao, Spain.
Martínez-Martínez V
Longarte A
Epelde-Elezcano N
Lamas I
Arbeloa IL
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Źródło :
The journal of physical chemistry letters [J Phys Chem Lett] 2021 Aug 12; Vol. 12 (31), pp. 7439-7441. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Boron Compounds*
Quantum Theory*
Humans
Czasopismo naukowe
Tytuł :
C=C Bond Oxidative Cleavage of BODIPY Photocages by Visible Light.
Autorzy :
Xu Y; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
Lin S; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
He R; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
Zhang Y; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
Gao Q; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
Ng DKP; Department of Chemistry, The Chinese University of Hong Kong-Shatin, N.T., Hong Kong, China.
Geng J; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Aug 05; Vol. 27 (44), pp. 11268-11272. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Boron*
Boron Compounds*
HeLa Cells ; Humans ; Light ; Oxidative Stress
Czasopismo naukowe
Tytuł :
BODIPYs with Photoactivatable Fluorescence.
Autorzy :
Zhang Y; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
Zheng Y; Laboratory for Molecular Photonics, Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA.
Meana Y; Laboratory for Molecular Photonics, Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA.
Raymo FM; Laboratory for Molecular Photonics, Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Aug 05; Vol. 27 (44), pp. 11257-11267. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Boron Compounds*
Fluorescent Dyes*
Fluorescence
Czasopismo naukowe
Tytuł :
Discovery of 3-aryl substituted benzoxaboroles as broad-spectrum inhibitors of serine- and metallo-β-lactamases.
Autorzy :
Yan YH; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Li ZF; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Ning XL; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Deng J; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Yu JL; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Luo Y; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
Wang Z; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
Li G; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Li GB; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. Electronic address: .
Xiao YC; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jun 01; Vol. 41, pp. 127956. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Boron Compounds/*pharmacology
beta-Lactamase Inhibitors/*chemical synthesis
beta-Lactamase Inhibitors/*pharmacology
Binding Sites ; Boron Compounds/chemical synthesis ; Boron Compounds/chemistry ; Escherichia coli/drug effects ; Escherichia coli/metabolism ; HEK293 Cells ; Humans ; Inhibitory Concentration 50 ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/metabolism ; Meropenem/pharmacology ; Models, Molecular ; Molecular Structure ; Protein Conformation ; beta-Lactamase Inhibitors/chemistry
Czasopismo naukowe
Tytuł :
Structure-Activity Relationship of para -Carborane Selective Estrogen Receptor β Agonists.
Autorzy :
Sedlák D; CZ-OPENSCREEN, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague, Czech Republic.
Wilson TA; Medicinal Chemistry Shared Resource, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, United States.
Tjarks W; Division of Medicinal Chemistry and Pharmacognosy College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Radomska HS; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Wang H; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Kolla JN; CZ-OPENSCREEN, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague, Czech Republic.
Leśnikowski ZJ; Laboratory of Medicinal Chemistry, Institute of Medical Biology PAS, 106 Lodowa Street, 93-232 Lodz, Poland.
Špičáková A; Department of Pharmacology, Faculty of Medicine, Palacky University, Hněvotínská 3, 77515 Olomouc, Czech Republic.
Ali T; Division of Medicinal Chemistry and Pharmacognosy College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Ishita K; Division of Medicinal Chemistry and Pharmacognosy College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Rakotondraibe LH; Division of Medicinal Chemistry and Pharmacognosy College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Vibhute S; Medicinal Chemistry Shared Resource, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, United States.
Wang D; Medicinal Chemistry Shared Resource, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, United States.
Anzenbacher P; Department of Pharmacology, Faculty of Medicine, Palacky University, Hněvotínská 3, 77515 Olomouc, Czech Republic.
Bennett C; Medicinal Chemistry Shared Resource, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, United States.; Drug Development Institute, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, United States.
Bartunek P; CZ-OPENSCREEN, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague, Czech Republic.
Coss CC; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.; Drug Development Institute, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jul 08; Vol. 64 (13), pp. 9330-9353. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Boron Compounds/*pharmacology
Estrogen Receptor beta/*agonists
Estrogens/*pharmacology
Boron Compounds/chemical synthesis ; Boron Compounds/chemistry ; Dose-Response Relationship, Drug ; Estrogens/chemical synthesis ; Estrogens/chemistry ; HEK293 Cells ; Humans ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Effects of boron-containing compounds in the fungal kingdom.
Autorzy :
Estevez-Fregoso E; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340, Mexico.
Farfán-García ED; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340, Mexico. Electronic address: .
García-Coronel IH; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340, Mexico; Unidad de Investigación, Hospital Regional de Alta Especialidad Ixtapaluca, Carretera Federal México-Puebla km 34.5, C.P. 56530, Ixtapaluca, State of Mexico, Mexico.
Martínez-Herrera E; Unidad de Investigación, Hospital Regional de Alta Especialidad Ixtapaluca, Carretera Federal México-Puebla km 34.5, C.P. 56530, Ixtapaluca, State of Mexico, Mexico.
Alatorre A; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340, Mexico.
Scorei RI; BioBoron Research Institute, Dunarii 31B Street, 207465, Podari, Romania.
Soriano-Ursúa MA; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340, Mexico. Electronic address: .
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Źródło :
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) [J Trace Elem Med Biol] 2021 May; Vol. 65, pp. 126714. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antifungal Agents/*pharmacology
Boron Compounds/*pharmacology
Fungi/*drug effects
Antifungal Agents/chemical synthesis ; Antifungal Agents/chemistry ; Boron Compounds/chemical synthesis ; Boron Compounds/chemistry ; Humans ; Microbial Sensitivity Tests
Czasopismo naukowe
Tytuł :
Carbazole- and Fluorene-Fused Aza-BODIPYs: NIR Fluorophores with High Brightness and Photostability.
Autorzy :
Rappitsch T; Graz University of Technology Institute of Analytical Chemistry and Food Chemistry, Stremayrgasse 9, 8010, Graz, Austria.
M Borisov S; Graz University of Technology Institute of Analytical Chemistry and Food Chemistry, Stremayrgasse 9, 8010, Graz, Austria.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Jul 21; Vol. 27 (41), pp. 10685-10692. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article
MeSH Terms :
Boron Compounds*
Fluorescent Dyes*
Carbazoles ; Fluorenes
Czasopismo naukowe
Tytuł :
BODIPY-Appended Pt(II) Complexes with High Toxicities and Anti-chemoresistance Performances in a Cisplatin Resistant In Vivo Model.
Autorzy :
Chong H; Department of Chemical and Chemical Engineering, Yangzhou University, Si-Wang-Ting Road, No. 180, Yangzhou, Jiangsu 225009, China.
Tan C; Department of Chemical and Chemical Engineering, Yangzhou University, Si-Wang-Ting Road, No. 180, Yangzhou, Jiangsu 225009, China.
Fang S; Department of Chemical and Chemical Engineering, Yangzhou University, Si-Wang-Ting Road, No. 180, Yangzhou, Jiangsu 225009, China.
Chen X; Analysis Centre, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Tao Q; Department of Chemical and Chemical Engineering, Yangzhou University, Si-Wang-Ting Road, No. 180, Yangzhou, Jiangsu 225009, China.
Yuan X; Department of Chemical and Chemical Engineering, Yangzhou University, Si-Wang-Ting Road, No. 180, Yangzhou, Jiangsu 225009, China.
Li J; College of Veterinary Medicine (Institute of Comparative Medicine), Yangzhou University, Yangzhou, Jiangsu 225009, China.
Zhai C; Department of Chemical and Chemical Engineering, Yangzhou University, Si-Wang-Ting Road, No. 180, Yangzhou, Jiangsu 225009, China.
Fei C; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College (Institute of Translational Medicine), Yangzhou University, Yangzhou, Jiangsu 225009, China.
Yang D; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College (Institute of Translational Medicine), Yangzhou University, Yangzhou, Jiangsu 225009, China.
Fan H; Testing Center of Yangzhou University, Yangzhou, Jiangsu 225009, China.
Shao H; College of Veterinary Medicine (Institute of Comparative Medicine), Yangzhou University, Yangzhou, Jiangsu 225009, China.
Qin A; College of Veterinary Medicine (Institute of Comparative Medicine), Yangzhou University, Yangzhou, Jiangsu 225009, China.
Wang G; School of Mathematical and Physical Sciences, University of Technology Sydney, City Campus, Broadway, Sydney, NSW 2007, Australia.
Shi Z; State Key Laboratory of Reproductive Medicine, Nanjing Maternity and Child Health Care Hospital, Analysis Centre, Women's Hospital of Nanjing Medical University, 140 Hanzhong Road, Nanjing, Jiangsu 210029, China.
Z'hang T; Department of Clinical Laboratory, The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi, Jiangsu 211166, China.
Yao H; Department of Chemical and Chemical Engineering, Yangzhou University, Si-Wang-Ting Road, No. 180, Yangzhou, Jiangsu 225009, China.
Li H; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College (Institute of Translational Medicine), Yangzhou University, Yangzhou, Jiangsu 225009, China.
Wang C; Testing Center of Yangzhou University, Yangzhou, Jiangsu 225009, China.
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Źródło :
Inorganic chemistry [Inorg Chem] 2021 Jul 05; Vol. 60 (13), pp. 10047-10055. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Boron Compounds/*pharmacology
Caenorhabditis elegans/*drug effects
Organoplatinum Compounds/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Boron Compounds/chemistry ; Cell Survival/drug effects ; Cisplatin/chemistry ; Cisplatin/pharmacology ; Dose-Response Relationship, Drug ; Mice ; Molecular Structure ; Organoplatinum Compounds/chemical synthesis ; Organoplatinum Compounds/chemistry
Czasopismo naukowe
Tytuł :
A Concise Route to Water-Soluble 2,6-Disubstituted BODIPY-Carbohydrate Fluorophores by Direct Ferrier-Type C-Glycosylation.
Autorzy :
Gómez AM; Instituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.
Uriel C; Instituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.
Oliden-Sánchez A; Departamento de Química Física, Universidad del Pais Vasco, UPV-EHU, Apartado 644, 48080 Bilbao, Spain.
Bañuelos J; Departamento de Química Física, Universidad del Pais Vasco, UPV-EHU, Apartado 644, 48080 Bilbao, Spain.
Garcia-Moreno I; Instituto de Química-Física Rocasolano, CSIC, Serrano 119, 28006 Madrid, Spain.
López JC; Instituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.
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Źródło :
The Journal of organic chemistry [J Org Chem] 2021 Jul 02; Vol. 86 (13), pp. 9181-9188. Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Boron Compounds*
Water*
Carbohydrates ; Glycosylation
Czasopismo naukowe
Tytuł :
Cyclopropyl Substituents Transform the Viscosity-Sensitive BODIPY Molecular Rotor into a Temperature Sensor.
Autorzy :
Vyšniauskas A; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.; Center of Physical Sciences and Technology, Saulėtekio av. 3, Vilnius 10257, Lithuania.
Cornell B; Physics Department, King's College London, Strand, London WC2R 2LS, U.K.
Sherin PS; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.
Maleckaitė K; Center of Physical Sciences and Technology, Saulėtekio av. 3, Vilnius 10257, Lithuania.
Kubánková M; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.
Izquierdo MA; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.
Vu TT; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.
Volkova YA; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.; Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russia.
Budynina EM; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.; Department of Chemistry, Lomonosov Moscow State University, Leninskie gory 1-3, Moscow 119991, Russia.
Molteni C; Physics Department, King's College London, Strand, London WC2R 2LS, U.K.
Kuimova MK; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London, Exhibition Road, London W12 0BZ, U.K.
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Źródło :
ACS sensors [ACS Sens] 2021 Jun 25; Vol. 6 (6), pp. 2158-2167. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Boron Compounds*
Fluorescent Dyes*
Temperature ; Viscosity
Czasopismo naukowe
Tytuł :
Design, Synthesis, and Biological Evaluation of Boron-Containing Macrocyclic Polyamines and Their Zinc(II) Complexes for Boron Neutron Capture Therapy.
Autorzy :
Ueda H; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
Suzuki M; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2-Asashiro-nishi, Kumatori, Osaka 590-0494, Japan.
Kuroda R; Research Institute for Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
Tanaka T; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
Aoki S; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.; Research Institute for Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.; Research Institute for Biomedical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jun 24; Vol. 64 (12), pp. 8523-8544. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Boron Compounds/*pharmacology
Coordination Complexes/*pharmacology
Macrocyclic Compounds/*pharmacology
Polyamines/*pharmacology
Antineoplastic Agents/chemical synthesis ; Boron Compounds/chemical synthesis ; Boron Neutron Capture Therapy ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Coordination Complexes/chemical synthesis ; Drug Design ; Humans ; Macrocyclic Compounds/chemical synthesis ; Polyamines/chemical synthesis ; Zinc/chemistry
Czasopismo naukowe
Tytuł :
BODIPY-vinyl dibromides as triplet sensitisers for photodynamic therapy and triplet-triplet annihilation upconversion.
Autorzy :
Dartar S; Department of Chemistry, Faculty of Science, İzmir Institute of Technology, İzmir, Turkey.
Ucuncu M; Department of Analytical Chemistry, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir, Turkey.
Karakus E; Organic Chemistry Laboratory, Chemistry Group, The Scientific & Technological Research Council of Turkey, National Metrology Institute (TUBITAK-UME), Kocaeli, Turkey.
Hou Y; State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, E 208 Western Campus, 2 Ling-Gong Road, Dalian 116012, P. R. China.
Zhao J; State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, E 208 Western Campus, 2 Ling-Gong Road, Dalian 116012, P. R. China.
Emrullahoglu M; Department of Photonics, Faculty of Science, İzmir Institute of Technology, Urla, 35430, İzmir, Turkey. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Jun 17; Vol. 57 (49), pp. 6039-6042.
Typ publikacji :
Journal Article
MeSH Terms :
Photochemotherapy*
Antineoplastic Agents/*pharmacology
Boron Compounds/*pharmacology
Bromides/*pharmacology
Photosensitizing Agents/*pharmacology
Vinyl Compounds/*pharmacology
A549 Cells ; Antineoplastic Agents/chemistry ; Boron Compounds/chemistry ; Bromides/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Optical Imaging ; Photosensitizing Agents/chemistry ; Vinyl Compounds/chemistry
Czasopismo naukowe
Tytuł :
BINOLated aminostyryl BODIPYs: a workable organic molecular platform for NIR circularly polarized luminescence.
Autorzy :
Jiménez J; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid, 28040, Spain. .
Díaz-Norambuena C; Departamento de Química Física, Universidad del País Vasco-EHU, Apartado 644, Bilbao, 48080, Spain.
Serrano S; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid, 28040, Spain. .
Ma SC; Department of Chemistry, San José State University, San José, CA 95192-0101, USA.
Moreno F; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid, 28040, Spain. .
Maroto BL; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid, 28040, Spain. .
Bañuelos J; Departamento de Química Física, Universidad del País Vasco-EHU, Apartado 644, Bilbao, 48080, Spain.
Muller G; Department of Chemistry, San José State University, San José, CA 95192-0101, USA.
de la Moya S; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid, 28040, Spain. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Jun 10; Vol. 57 (47), pp. 5750-5753.
Typ publikacji :
Journal Article
MeSH Terms :
Luminescence*
Boron Compounds/*chemistry
Boron Compounds/chemical synthesis ; Infrared Rays ; Luminescent Measurements ; Molecular Structure ; Solubility ; Water/chemistry
Czasopismo naukowe
Tytuł :
Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine.
Autorzy :
Prattes M; Institute of Molecular Biosciences, University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.
Grishkovskaya I; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria.
Hodirnau VV; Institute of Science and Technology Austria, Klosterneuburg, Austria.
Rössler I; Institute of Molecular Biosciences, University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.
Klein I; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Hetzmannseder C; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Zisser G; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Gruber CC; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Gruber K; Institute of Molecular Biosciences, University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.; Field of Excellence BioHealth - University of Graz, Graz, Austria.
Haselbach D; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria. .
Bergler H; Institute of Molecular Biosciences, University of Graz, Graz, Austria. .; BioTechMed-Graz, Graz, Austria. .; Field of Excellence BioHealth - University of Graz, Graz, Austria. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 09; Vol. 12 (1), pp. 3483. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATPases Associated with Diverse Cellular Activities/*chemistry
Adenosine Triphosphatases/*chemistry
Boron Compounds/*chemistry
Saccharomyces cerevisiae Proteins/*chemistry
AAA Domain ; ATPases Associated with Diverse Cellular Activities/antagonists & inhibitors ; ATPases Associated with Diverse Cellular Activities/genetics ; ATPases Associated with Diverse Cellular Activities/metabolism ; Adenosine Triphosphatases/antagonists & inhibitors ; Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Binding Sites ; Boron Compounds/pharmacology ; Drug Resistance/genetics ; Enzyme Activation/drug effects ; Enzyme Activation/genetics ; Mutation ; Nucleotides/chemistry ; Saccharomyces cerevisiae Proteins/antagonists & inhibitors ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
Mitochondria selective trackers for long-term imaging based on readily accessible neutral BODIPYs.
Autorzy :
Ramos-Torres Á; Universidad de Alcalá, Departamento de Biología de Sistemas, Facultad de Medicina y Ciencias de la Salud, Campus Universitario, Crtra A2, Km. 33,600 28805, Alcalá de Henares, Madrid, Spain.
Avellanal-Zaballa E; Departamento de Química-Física, Universidad del País Vasco (UPV/EHU), Apartado 644, Bilbao 48080, Spain.
García-Garrido F; Departamento de Química Orgánica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid 28040, Spain. .
Fernández-Martínez AB; Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, Darwin 2, Madrid 28049, Spain.
Prieto-Castañeda A; Departamento de Química Orgánica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid 28040, Spain. .
Agarrabeitia AR; Departamento de Química Orgánica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid 28040, Spain. .
Bañuelos J; Departamento de Química-Física, Universidad del País Vasco (UPV/EHU), Apartado 644, Bilbao 48080, Spain.
García-Moreno I; Departamento de Sistemas de Baja Dimensionalidad, Superficies y Materia Condensada, Instituto de Química-Física 'Rocasolano', CSIC, Serrano 119, Madrid 28006, Spain.
Lucio-Cazaña FJ; Universidad de Alcalá, Departamento de Biología de Sistemas, Facultad de Medicina y Ciencias de la Salud, Campus Universitario, Crtra A2, Km. 33,600 28805, Alcalá de Henares, Madrid, Spain.
Ortiz MJ; Departamento de Química Orgánica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, Madrid 28040, Spain. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 May 27; Vol. 57 (43), pp. 5318-5321.
Typ publikacji :
Journal Article
MeSH Terms :
Optical Imaging*
Boron Compounds/*chemistry
Fluorescent Dyes/*chemistry
Mitochondria/*chemistry
Benzyl Compounds/chemistry ; Benzyl Compounds/metabolism ; Boron Compounds/chemical synthesis ; Fluorescent Dyes/chemical synthesis ; Humans ; Mitochondria/metabolism ; Molecular Structure ; PC-3 Cells ; Photochemical Processes
Czasopismo naukowe

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