Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide-1 Analogue.
Autorzy:
Chandrashekar C; The Florey, University of Melbourne, Parkville, Victoria 3010, Australia. Lin F; The Florey, University of Melbourne, Parkville, Victoria 3010, Australia. Nishiuchi Y; GlyTech, Inc., 134 Chudoji Minamimachi, Kyoto 600-8813, Japan.; Graduate School of Science, Tohoku University, Sendai 980-8579, Miyagi, Japan. Mohammed SF; Department of Anatomy and Physiology, University of Melbourne, Parkville, Victoria 3010, Australia. White BF; Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria 3084, Australia. Arsenakis Y; Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria 3084, Australia. Yuliantie E; Drug Discovery Biology and ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia. Zhao P; Drug Discovery Biology and ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia. van Dun S; EnzyTag B.V. Daelderweg 9, Nuth NL-6361HK, The Netherlands. Koijen A; EnzyTag B.V. Daelderweg 9, Nuth NL-6361HK, The Netherlands. Kajihara Y; Graduate School of Science, Osaka University, Toyonaka 560-0043, Osaka, Japan. Wootten D; Drug Discovery Biology and ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia. Dodd GT; Department of Anatomy and Physiology, University of Melbourne, Parkville, Victoria 3010, Australia. van den BosLJ; EnzyTag B.V. Daelderweg 9, Nuth NL-6361HK, The Netherlands. Wade JD; The Florey, University of Melbourne, Parkville, Victoria 3010, Australia.; School of Chemistry, University of Melbourne, Parkville, Victoria 3052, Australia. Hossain MA; The Florey, University of Melbourne, Parkville, Victoria 3010, Australia.; School of Chemistry, University of Melbourne, Parkville, Victoria 3052, Australia.
Glycosylation Improves the Proteolytic Stability of Exenatide.
Autorzy:
Chandrashekar C; The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3052, Australia. Nishiuchi Y; GlyTech, Inc., 134 Chudoji Minamimachi, Kyoto 600-8813, Japan.; Graduate School of Science, Tohoku University, Sendai, Miyagi 980-8579, Japan. White BF; Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria 3084, Australia. Arsenakis Y; Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria 3084, Australia. Lin F; The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3052, Australia. McNeill SM; Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia. Zhao P; Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia.; ARC Centre for Cryo-Electron Microscopy of Membrane Proteins (CCeMMP), Monash Institute of Pharmaceutical Sciences, Parkville, Victoria 3052, Australia. van Dun S; EnzyTag B.V., Daelderweg 9, 6361HK Nuth, The Netherlands. Koijen A; EnzyTag B.V., Daelderweg 9, 6361HK Nuth, The Netherlands. Kajihara Y; Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043 Japan. Wootten D; Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia.; ARC Centre for Cryo-Electron Microscopy of Membrane Proteins (CCeMMP), Monash Institute of Pharmaceutical Sciences, Parkville, Victoria 3052, Australia. van den BosLJ; EnzyTag B.V., Daelderweg 9, 6361HK Nuth, The Netherlands. Wade JD; The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3052, Australia.; The Florey Department of Neuroscience and Mental Health, Parkville, Victoria 3010, Australia.; School of Chemistry, Parkville, Victoria 3010, Australia. Hossain MA; The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3052, Australia.; The Florey Department of Neuroscience and Mental Health, Parkville, Victoria 3010, Australia.; School of Chemistry, Parkville, Victoria 3010, Australia.; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria 3010, Australia.
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Źródło:
Bioconjugate chemistry [Bioconjug Chem] 2023 Jun 21; Vol. 34 (6), pp. 1014-1018. Date of Electronic Publication: 2023 May 16.
Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis.
Autorzy:
Liu Y; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden. Güler R; Affibody AB, 171 65 Solna, Sweden. Liao Y; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden. Vorobyeva A; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden. Widmark O; Affibody AB, 171 65 Solna, Sweden. Meuleman TJ; EnzyTag BV, Daelderweg 9, NL-6361 HK Nuth, The Netherlands. Koijen A; EnzyTag BV, Daelderweg 9, NL-6361 HK Nuth, The Netherlands. van den BosLJ; EnzyTag BV, Daelderweg 9, NL-6361 HK Nuth, The Netherlands. Naasz R; EnzyTag BV, Daelderweg 9, NL-6361 HK Nuth, The Netherlands. Bodenko V; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia. Orlova A; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia.; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, 752 37 Uppsala, Sweden. Ekblad C; Affibody AB, 171 65 Solna, Sweden. Tolmachev V; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia. Frejd FY; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.; Affibody AB, 171 65 Solna, Sweden.
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Źródło:
Pharmaceutics [Pharmaceutics] 2022 Nov 19; Vol. 14 (11). Date of Electronic Publication: 2022 Nov 19.
From Farm to Pharma: An Overview of Industrial Heparin Manufacturing Methods.
Autorzy:
van der Meer JY; Development and Technical Support Aspen Oss, Kloosterstraat 6, P.O. Box 98, 5340 AB Oss, The Netherlands. . Kellenbach E; Development and Technical Support Aspen Oss, Kloosterstraat 6, P.O. Box 98, 5340 AB Oss, The Netherlands. . van den BosLJ; Development and Technical Support Aspen Oss, Kloosterstraat 6, P.O. Box 98, 5340 AB Oss, The Netherlands. .
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