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Tytuł :
Inhibition of Pyruvate Kinase From Thermoanaerobacterium saccharolyticum by IMP Is Independent of the Extra-C Domain.
Autorzy :
Fenton CA; Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, United States.
Tang Q; Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, United States.
Olson DG; Thayer School of Engineering, Dartmouth College, Hanover, NH, United States.; Oak Ridge National Laboratories, Center for Bioenergy Innovation, Oak Ridge, TN, United States.
Maloney MI; Thayer School of Engineering, Dartmouth College, Hanover, NH, United States.; Oak Ridge National Laboratories, Center for Bioenergy Innovation, Oak Ridge, TN, United States.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, Kansas City, KS, United States.
Lynd LR; Thayer School of Engineering, Dartmouth College, Hanover, NH, United States.; Oak Ridge National Laboratories, Center for Bioenergy Innovation, Oak Ridge, TN, United States.
Fenton AW; Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, United States.
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Źródło :
Frontiers in microbiology [Front Microbiol] 2021 Feb 17; Vol. 12, pp. 628308. Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Staphylococcus aureus Fatty Acid Kinase FakA Modulates Pathogenesis during Skin Infection via Proteases.
Autorzy :
Ridder MJ; Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Daly SM; Department of Pharmaceutical Sciences, University of New Mexico College of Pharmacy, Albuquerque, New Mexico, USA.
Triplett KD; Department of Pharmaceutical Sciences, University of New Mexico College of Pharmacy, Albuquerque, New Mexico, USA.
Seawell NA; Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Hall PR; Department of Pharmaceutical Sciences, University of New Mexico College of Pharmacy, Albuquerque, New Mexico, USA.
Bose JL; Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA .
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Źródło :
Infection and immunity [Infect Immun] 2020 Jul 21; Vol. 88 (8). Date of Electronic Publication: 2020 Jul 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bacterial Proteins/*immunology
Metalloendopeptidases/*immunology
Phosphotransferases (Carboxyl Group Acceptor)/*immunology
Serine Endopeptidases/*immunology
Skin Ulcer/*immunology
Staphylococcal Skin Infections/*immunology
Staphylococcus aureus/*pathogenicity
Animals ; Bacterial Load ; Bacterial Proteins/genetics ; Bacterial Toxins/genetics ; Bacterial Toxins/immunology ; Chemokine CCL4/genetics ; Chemokine CCL4/immunology ; Female ; Gene Expression Regulation ; Hemolysin Proteins/genetics ; Hemolysin Proteins/immunology ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Interleukin-17/genetics ; Interleukin-17/immunology ; Interleukin-1alpha/genetics ; Interleukin-1alpha/immunology ; Interleukin-1beta/genetics ; Interleukin-1beta/immunology ; Interleukin-6/genetics ; Interleukin-6/immunology ; Metalloendopeptidases/deficiency ; Metalloendopeptidases/genetics ; Mice ; Phosphotransferases (Carboxyl Group Acceptor)/deficiency ; Phosphotransferases (Carboxyl Group Acceptor)/genetics ; Serine Endopeptidases/deficiency ; Serine Endopeptidases/genetics ; Signal Transduction ; Skin/immunology ; Skin/microbiology ; Skin/pathology ; Skin Ulcer/genetics ; Skin Ulcer/microbiology ; Skin Ulcer/pathology ; Staphylococcal Skin Infections/genetics ; Staphylococcal Skin Infections/microbiology ; Staphylococcal Skin Infections/pathology ; Staphylococcus aureus/enzymology ; Staphylococcus aureus/genetics ; Staphylococcus aureus/immunology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology ; Virulence Factors/genetics ; Virulence Factors/immunology
Czasopismo naukowe
Tytuł :
Exogenous Fatty Acids Remodel Staphylococcus aureus Lipid Composition through Fatty Acid Kinase.
Autorzy :
DeMars Z; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Singh VK; Department of Microbiology and Immunology, A.T. Still University of Health Sciences, Kirksville, Missouri, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA .
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Źródło :
Journal of bacteriology [J Bacteriol] 2020 Jun 25; Vol. 202 (14). Date of Electronic Publication: 2020 Jun 25 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Bacterial Proteins/*metabolism
Lipids/*chemistry
Phosphotransferases/*metabolism
Staphylococcus aureus/*enzymology
Animals ; Bacterial Proteins/genetics ; Fatty Acids/metabolism ; Lipid Metabolism ; Mice ; Mice, Inbred C57BL ; Oleic Acid/metabolism ; Phosphotransferases/genetics ; Skin/microbiology ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/genetics ; Staphylococcus aureus/growth & development ; Staphylococcus aureus/metabolism
Czasopismo naukowe
Tytuł :
Controlling the Growth of the Skin Commensal Staphylococcus epidermidis Using d-Alanine Auxotrophy.
Autorzy :
Dodds D; Azitra Inc., Farmington, Connecticut, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Deng MD; Bio-Technical Resources, Manitowoc, Wisconsin, USA.
Dubé GR; Azitra Inc., Farmington, Connecticut, USA.
Grossman TH; Azitra Inc., Farmington, Connecticut, USA.
Kaiser A; Azitra Inc., Farmington, Connecticut, USA.
Kulkarni K; Azitra Inc., Farmington, Connecticut, USA.
Leger R; Azitra Inc., Farmington, Connecticut, USA.
Mootien-Boyd S; Azitra Inc., Farmington, Connecticut, USA.
Munivar A; Azitra Inc., Farmington, Connecticut, USA.; Department of Psychiatry, Yale-New Haven Hospital, New Haven, Connecticut, USA.
Oh J; Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Pestrak M; Azitra Inc., Farmington, Connecticut, USA.
Rajpura K; Azitra Inc., Farmington, Connecticut, USA.
Tikhonov AP; Azitra Inc., Farmington, Connecticut, USA.
Turecek T; Azitra Inc., Farmington, Connecticut, USA.
Whitfill T; Azitra Inc., Farmington, Connecticut, USA .; Department of Pediatrics, Yale University, New Haven, Connecticut, USA.
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Źródło :
MSphere [mSphere] 2020 Jun 10; Vol. 5 (3). Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Staphylococcus aureus Fibronectin Binding Protein A Mediates Biofilm Development and Infection.
Autorzy :
Gries CM; Division of Biomedical Sciences, University of California Riverside School of Medicine, Riverside, California, USA .
Biddle T; Division of Biomedical Sciences, University of California Riverside School of Medicine, Riverside, California, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Kielian T; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Lo DD; Division of Biomedical Sciences, University of California Riverside School of Medicine, Riverside, California, USA.
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Źródło :
Infection and immunity [Infect Immun] 2020 Apr 20; Vol. 88 (5). Date of Electronic Publication: 2020 Apr 20 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Adhesins, Bacterial/*metabolism
Bacterial Proteins/*metabolism
Staphylococcal Infections/*metabolism
Staphylococcal Infections/*microbiology
Staphylococcus aureus/*metabolism
Staphylococcus aureus/*pathogenicity
Animals ; Bacterial Adhesion/physiology ; Biofilms/growth & development ; Humans ; Mice ; Mice, Inbred C57BL ; Protein Binding/physiology
Czasopismo naukowe
Tytuł :
Genetic Manipulations of Staphylococcal Chromosomal DNA.
Autorzy :
Austin CM; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2020; Vol. 2069, pp. 103-111.
Typ publikacji :
Journal Article
MeSH Terms :
CRISPR-Cas Systems*
Gene Editing*
Point Mutation*
Chromosomes, Bacterial/*genetics
Staphylococcus aureus/*genetics
Czasopismo naukowe
Tytuł :
CidR and CcpA Synergistically Regulate Staphylococcus aureus cidABC Expression.
Autorzy :
Sadykov MR; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Windham IH; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Widhelm TJ; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Yajjala VK; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Watson SM; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Endres JL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Bavari AI; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Thomas VC; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Bayles KW; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA .
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Źródło :
Journal of bacteriology [J Bacteriol] 2019 Nov 05; Vol. 201 (23). Date of Electronic Publication: 2019 Nov 05 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression Regulation, Bacterial*
Bacterial Proteins/*genetics
DNA-Binding Proteins/*genetics
Staphylococcus aureus/*genetics
Bacterial Proteins/metabolism ; Base Sequence ; Biofilms/growth & development ; DNA-Binding Proteins/metabolism ; Electrophoretic Mobility Shift Assay ; Genes, Reporter ; Operon ; Promoter Regions, Genetic ; Protein Binding ; Real-Time Polymerase Chain Reaction ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Staphylococcus aureus/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Contribution of YjbIH to Virulence Factor Expression and Host Colonization in Staphylococcus aureus .
Autorzy :
Austin CM; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics and Immunology, Kansas City, Kansas, USA.
Garabaglu S; Rutgers, the State University of New Jersey, Department of Biochemistry and Microbiology, New Brunswick, New Jersey, USA.
Krute CN; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics and Immunology, Kansas City, Kansas, USA.
Ridder MJ; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics and Immunology, Kansas City, Kansas, USA.
Seawell NA; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics and Immunology, Kansas City, Kansas, USA.
Markiewicz MA; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics and Immunology, Kansas City, Kansas, USA.
Boyd JM; Rutgers, the State University of New Jersey, Department of Biochemistry and Microbiology, New Brunswick, New Jersey, USA.
Bose JL; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics and Immunology, Kansas City, Kansas, USA .
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Źródło :
Infection and immunity [Infect Immun] 2019 May 21; Vol. 87 (6). Date of Electronic Publication: 2019 May 21 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Bacterial*
Bacterial Proteins/*metabolism
Oxidoreductases/*metabolism
Staphylococcal Infections/*microbiology
Staphylococcus aureus/*enzymology
Staphylococcus aureus/*growth & development
Virulence Factors/*genetics
Animals ; Bacterial Proteins/genetics ; Female ; Humans ; Metalloendopeptidases/genetics ; Metalloendopeptidases/metabolism ; Mice ; Mice, Inbred C57BL ; Operon ; Oxidoreductases/genetics ; Staphylococcus aureus/genetics ; Staphylococcus aureus/metabolism ; Virulence Factors/metabolism
Czasopismo naukowe
Tytuł :
Bacterial Community Succession, Transmigration, and Differential Gene Transcription in a Controlled Vertebrate Decomposition Model.
Autorzy :
Burcham ZM; Department of Biological Sciences, Mississippi State University, Starkville, MS, United States.
Pechal JL; Department of Entomology, Michigan State University, East Lansing, MI, United States.
Schmidt CJ; Department of Pathology, University of Michigan, Ann Arbor, MI, United States.
Bose JL; Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, KS, United States.
Rosch JW; Department of Infectious Disease, St. Jude Children's Research Hospital, Memphis, TN, United States.
Benbow ME; Department of Entomology, Michigan State University, East Lansing, MI, United States.; Department of Osteopathic Medical Specialties, Michigan State University, East Lansing, MI, United States.
Jordan HR; Department of Biological Sciences, Mississippi State University, Starkville, MS, United States.
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Źródło :
Frontiers in microbiology [Front Microbiol] 2019 Apr 18; Vol. 10, pp. 745. Date of Electronic Publication: 2019 Apr 18 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The Small RNA Teg41 Regulates Expression of the Alpha Phenol-Soluble Modulins and Is Required for Virulence in Staphylococcus aureus.
Autorzy :
Zapf RL; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Wiemels RE; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Keogh RA; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Holzschu DL; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Howell KM; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Trzeciak E; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Caillet AR; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
King KA; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Selhorst SA; Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Naldrett MJ; Proteomics and Metabolomics Facility, Center for Biotechnology, University of Nebraska Lincoln, Lincoln, Nebraska, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Carroll RK; Department of Biological Sciences, Ohio University, Athens, Ohio, USA .
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Źródło :
MBio [mBio] 2019 Feb 05; Vol. 10 (1). Date of Electronic Publication: 2019 Feb 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression Regulation, Bacterial*
Bacterial Toxins/*biosynthesis
RNA, Bacterial/*metabolism
RNA, Small Untranslated/*metabolism
Staphylococcus aureus/*genetics
Staphylococcus aureus/*growth & development
Virulence Factors/*biosynthesis
Abscess/microbiology ; Abscess/pathology ; Animals ; Disease Models, Animal ; Genetic Complementation Test ; Hemolysis ; Humans ; Mice ; Sequence Deletion ; Staphylococcal Infections/microbiology ; Staphylococcal Infections/pathology ; Virulence
Czasopismo naukowe
Tytuł :
Inactivation of the exogenous fatty acid utilization pathway leads to increased resistance to unsaturated fatty acids in Staphylococcus aureus.
Autorzy :
Krute CN; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Ridder MJ; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Seawell NA; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
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Źródło :
Microbiology (Reading, England) [Microbiology (Reading)] 2019 Feb; Vol. 165 (2), pp. 197-207. Date of Electronic Publication: 2018 Dec 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosynthetic Pathways/*genetics
Fatty Acids/*metabolism
Fatty Acids, Unsaturated/*toxicity
Staphylococcus aureus/*drug effects
Bacterial Proteins/genetics ; Fatty Acids, Unsaturated/metabolism ; Mutation ; Phosphotransferases/genetics ; Sigma Factor/genetics ; Staphylococcal Infections/immunology ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/genetics ; Staphylococcus aureus/growth & development ; Staphylococcus aureus/metabolism
Czasopismo naukowe
Tytuł :
Interplay of Nitric Oxide Synthase (NOS) and SrrAB in Modulation of Staphylococcus aureus Metabolism and Virulence.
Autorzy :
James KL; Department of Microbiology and Cell Science, IFAS, University of Florida, Gainesville, Florida, USA.
Mogen AB; Department of Microbiology and Cell Science, IFAS, University of Florida, Gainesville, Florida, USA.
Brandwein JN; Department of Microbiology and Cell Science, IFAS, University of Florida, Gainesville, Florida, USA.
Orsini SS; Department of Microbiology and Cell Science, IFAS, University of Florida, Gainesville, Florida, USA.
Ridder MJ; Department of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, Kansas City, Kansas, USA.
Markiewicz MA; Department of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, Kansas City, Kansas, USA.
Bose JL; Department of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, Kansas City, Kansas, USA.
Rice KC; Department of Microbiology and Cell Science, IFAS, University of Florida, Gainesville, Florida, USA .
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Źródło :
Infection and immunity [Infect Immun] 2019 Jan 24; Vol. 87 (2). Date of Electronic Publication: 2019 Jan 24 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins*/genetics
Repressor Proteins*/genetics
Staphylococcus aureus*/metabolism
Staphylococcus aureus*/pathogenicity
Nitric Oxide Synthase/*metabolism
Virulence/*physiology
Cells, Cultured ; Gene Expression Regulation, Bacterial/physiology ; Mutation ; Nitrates/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/genetics ; Oxidative Stress/physiology ; Transcription, Genetic ; Virulence/genetics
Czasopismo naukowe

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