Atopic Dermatitis and Psoriasis are Diagnosed Clinically and Treated Empirically.
Autorzy:
Aggarwal P; University of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH, 45267, USA. . BowersNL; Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC, USA. Muddasani S; University of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH, 45267, USA. Fleischer AB Jr; University of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH, 45267, USA. Feldman SR; Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
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Źródło:
Dermatology and therapy [Dermatol Ther (Heidelb)] 2022 Mar; Vol. 12 (3), pp. 611-614. Date of Electronic Publication: 2022 Feb 04.
Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study.
Autorzy:
Chandrasekaran D; Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.; Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK. Sobocan M; Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.; Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK.; Divison for Gynaecology and Perinatology, University Medical Centre Maribor, 2000 Maribor, Slovenia. Blyuss O; School of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UK.; Department of Paediatrics and Paediatric Infectious Diseases, Sechenov First Moscow State Medical University, Moscow 119991, Russia.; World-Class Research Center 'Digital Biodesign and Personalized Healthcare', Sechenov First Moscow State Medical University, Moscow 119991, Russia. Miller RE; Department of Medical Oncology, Barts Health NHS Trust, London EC1A 7BE, UK. Evans O; Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Crusz SM; Department of Medical Oncology, Barts Health NHS Trust, London EC1A 7BE, UK. Mills-Baldock T; Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK. Sun L; Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.; Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK. Hammond RFL; Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK. Gaba F; Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Jenkins LA; North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK. Ahmed M; North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK. Kumar A; North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK. Jeyarajah A; Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK. Lawrence AC; Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK. Brockbank E; Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK. Phadnis S; Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK. Quigley M; Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK. El Khouly F; Department of Medical Oncology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK. Wuntakal R; Department of Gynaecology, Barking, Havering & Redbridge University Hospitals, Essex RM7 0AG, UK. Faruqi A; Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK. Trevisan G; Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK. Casey L; Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK. Burghel GJ; Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK. Schlecht H; Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK. Bulman M; Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK. Smith P; Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK. BowersNL; Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK. Legood R; Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK. Lockley M; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Wallace A; Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK. Singh N; Department of Pathology, Barts Health NHS Trust, London E1 1FR, UK. Evans DG; Manchester Centre for Genomic Medicine, Saint Marys Hospital, Manchester M13 9WL, UK. Manchanda R; Wolfson Institute of Population Health, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.; Department of Gynaecological Oncology, Barts Health NHS Trust, London EC1 1BB, UK.; Department of Health Services Research, Faculty of Public Health & Policy, London School of Hygiene & Tropical Medicine, London WC1H 9SH, UK.
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Źródło:
Cancers [Cancers (Basel)] 2021 Aug 27; Vol. 13 (17). Date of Electronic Publication: 2021 Aug 27.
Gene Panel Testing for Breast Cancer Reveals Differential Effect of Prior BRCA1/2 Probability.
Autorzy:
Evans DG; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, UK.; Prevent Breast Cancer Centre, Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, Manchester M23 9LT, UK.; Manchester Breast Centre, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK. van Veen EM; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, UK. Woodward ER; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, UK. Harkness EF; Prevent Breast Cancer Centre, Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, Manchester M23 9LT, UK. Ellingford JM; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, UK. BowersNL; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK. Wallace AJ; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK. Howell SJ; Prevent Breast Cancer Centre, Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, Manchester M23 9LT, UK.; Manchester Breast Centre, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M20 4GJ, UK. Howell A; Prevent Breast Cancer Centre, Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, Manchester M23 9LT, UK.; Manchester Breast Centre, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK. Lalloo F; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK. Newman WG; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, UK. Smith MJ; NW Genomic Laboratory Hub, Manchester Centre for Genomic Medicine, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, UK.
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Źródło:
Cancers [Cancers (Basel)] 2021 Aug 18; Vol. 13 (16). Date of Electronic Publication: 2021 Aug 18.
Risk of Contralateral Breast Cancer in Women with and without Pathogenic Variants in BRCA1, BRCA2 , and TP53 Genes in Women with Very Early-Onset (<36 Years) Breast Cancer.
Autorzy:
Hyder Z; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK. Harkness EF; Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.; Prevent Breast Cancer Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, Manchester M23 9LT, UK. Woodward ER; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK. BowersNL; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK. Pereira M; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK. Wallace AJ; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK. Howell SJ; Prevent Breast Cancer Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, Manchester M23 9LT, UK.; Manchester Breast Centre, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK. Howell A; Prevent Breast Cancer Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, Manchester M23 9LT, UK.; Manchester Breast Centre, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK. Lalloo F; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK. Newman WG; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK. Smith MJ; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK. Evans DG; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK.; Prevent Breast Cancer Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, Manchester M23 9LT, UK.; Manchester Breast Centre, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
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Źródło:
Cancers [Cancers (Basel)] 2020 Feb 07; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 07.
Immune suppression by neutrophils in HIV-1 infection: role of PD-L1/PD-1 pathway.
Autorzy:
BowersNL; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America. Helton ES; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America. Huijbregts RP; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America. Goepfert PA; Center for AIDS Research, University of Alabama at Birmingham, Birmingham, Alabama, United States of America; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America. Heath SL; Center for AIDS Research, University of Alabama at Birmingham, Birmingham, Alabama, United States of America; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America. Hel Z; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America; Center for AIDS Research, University of Alabama at Birmingham, Birmingham, Alabama, United States of America; Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2014 Mar 13; Vol. 10 (3), pp. e1003993. Date of Electronic Publication: 2014 Mar 13 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability.
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