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Tytuł :
Application of a multi-institutional nomogram predicting salvage whole brain radiation-free survival to patients treated with postoperative stereotactic radiotherapy for brain metastases.
Autorzy :
Mousli A; Radiation oncology department, CHU-UCL-Namur, site Sainte-Elisabeth, université catholique de Louvain, Namur, Belgium; Radiation oncology department, Tunis El Manar university, Salah Azaiez Institute, Tunis, Tunisia. Electronic address: .
Bihin B; Biostatistics unit, CHU-UCL-Namur, site Godinne, université catholique de Louvain, Yvoir, Belgium. Electronic address: .
Gustin T; Neurosurgery department, CHU-UCL-Namur, site Godinne, université catholique de Louvain, Yvoir, Belgium.
Koerts G; Neurosurgery department, centre hospitalier régional Sambre et Meuse, Namur, Belgium.
Mouchamps M; Neurosurgery department, centre hospitalier régional de Liège, Liège, Belgium; Neurosurgery department, centre hospitalier chrétien Saint-Joseph, Liège, Belgium.
Daisne JF; Radiation oncology department, CHU-UCL-Namur, site Sainte-Elisabeth, université catholique de Louvain, Namur, Belgium; Radiation oncology department, katholieke universiteit Leuven, university hospitals Leuven, Leuven, Belgium.
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Źródło :
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2021 Apr; Vol. 25 (2), pp. 141-146. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Cranial Irradiation*/statistics & numerical data
Nomograms*
Brain Neoplasms/*radiotherapy
Brain Neoplasms/*secondary
Radiosurgery/*methods
Salvage Therapy/*methods
Adult ; Aged ; Aged, 80 and over ; Area Under Curve ; Brain Neoplasms/epidemiology ; Brain Neoplasms/surgery ; Confidence Intervals ; Female ; Humans ; Incidence ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Recurrence, Local/epidemiology ; Postoperative Period ; ROC Curve ; Radiosurgery/statistics & numerical data ; Retrospective Studies ; Salvage Therapy/statistics & numerical data ; Time Factors
Czasopismo naukowe
Tytuł :
Hypofractionated stereotactic radiotherapy for large brain metastases: Optimizing the dosimetric parameters.
Autorzy :
Brun L; Department of radiation oncology, Jean-Perrin center, 63011 Clermont-Ferrand, France.
Dupic G; Department of radiation oncology, Jean-Perrin center, 63011 Clermont-Ferrand, France. Electronic address: .
Chassin V; Department of medical physics, Jean-Perrin center, Clermont-Ferrand, France.
Chautard E; Clermont Auvergne university, INSERM, U1240 IMoST, 63000 Clermont-Ferrand, France; Department of pathology, Clermont Auvergne university, Jean-Perrin center, 63011 Clermont-Ferrand, France.
Moreau J; Department of radiation oncology, Jean-Perrin center, 63011 Clermont-Ferrand, France.
Dedieu V; Department of medical physics, Jean-Perrin center, Clermont-Ferrand, France.
Khalil T; Department of neurosurgery, Clermont-Ferrand hospital, 63003 Clermont-Ferrand, France.
Verrelle P; Department of radiation oncology, Jean-Perrin center, 63011 Clermont-Ferrand, France.
Lapeyre M; Department of radiation oncology, Jean-Perrin center, 63011 Clermont-Ferrand, France.
Biau J; Department of radiation oncology, Jean-Perrin center, 63011 Clermont-Ferrand, France; Clermont Auvergne university, INSERM, U1240 IMoST, 63000 Clermont-Ferrand, France.
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Źródło :
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2021 Feb; Vol. 25 (1), pp. 1-7. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Radiation Dose Hypofractionation*
Brain Neoplasms/*radiotherapy
Brain Neoplasms/*secondary
Radiosurgery/*methods
Radiotherapy, Intensity-Modulated/*methods
Adult ; Aged ; Aged, 80 and over ; Brain/diagnostic imaging ; Brain/radiation effects ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/pathology ; Humans ; Middle Aged ; Organs at Risk/diagnostic imaging ; Tomography, X-Ray Computed ; Tumor Burden
Czasopismo naukowe
Tytuł :
Glioblastoma in a female neurofibromatosis 1 patient without IDH1, BRAF V600E, and TERT promoter mutations: A case report.
Autorzy :
Cai JW; Department of Neurosurgery.
Chen XY; Department of Neurosurgery.
Chen JY; Department of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Wu ZY; Department of Neurosurgery.
Wu XY; Department of Neurosurgery.
Yu LH; Department of Neurosurgery.
You HH; Department of Neurosurgery.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Apr 02; Vol. 100 (13), pp. e25346.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Biomarkers, Tumor/*genetics
Brain Neoplasms/*diagnosis
Glioblastoma/*diagnosis
Neurofibromatosis 1/*diagnosis
Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Brain Neoplasms/surgery ; Craniotomy ; Female ; Glioblastoma/genetics ; Glioblastoma/pathology ; Glioblastoma/surgery ; Humans ; Isocitrate Dehydrogenase/genetics ; Magnetic Resonance Imaging ; Middle Aged ; Mutation ; Neurofibromatosis 1/complications ; Neurofibromatosis 1/genetics ; Parietal Lobe/diagnostic imaging ; Parietal Lobe/pathology ; Parietal Lobe/surgery ; Promoter Regions, Genetic/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Telomerase/genetics ; Temporal Lobe/diagnostic imaging ; Temporal Lobe/pathology ; Temporal Lobe/surgery ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Demethoxycurcumin Suppresses Proliferation, Migration, and Invasion of Human Brain Glioblastoma Multiforme GBM 8401 Cells via PI3K/Akt Pathway.
Autorzy :
Su RY; Division of Clinical Pathology, Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, R.O.C.; Department of Pathology and Laboratory Medicine, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan, R.O.C.
Hsueh SC; Division of Hematology and Oncology, Cheng Hsin General Hospital, Taipei, Taiwan, R.O.C.
Chen CY; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
Hsu MJ; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
Lu HF; Department of Clinical Pathology, Cheng Hsin General Hospital, Taipei, Taiwan, R.O.C.; Department of Restaurant, Hotel and Institutional Management, Fu-Jen Catholic University, New Taipei, Taiwan, R.O.C.
Peng SF; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chen PY; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
Lien JC; School of Pharmacy, China Medical University, Taichung, Taiwan, R.O.C.
Chen YL; Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsinchu, Taiwan, R.O.C.
Chueh FS; Department of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan, R.O.C.
Chung JG; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
Yeh MY; Department of Education and Research, Cheng-Hsin General Hospital, Taipei, Taiwan, R.O.C.; .
Huang YP; Department of Physiology, School of Medicine, China Medical University, Taichung, Taiwan, R.O.C. .
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 1859-1870.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Brain Neoplasms/*drug therapy
Cell Movement/*drug effects
Cell Proliferation/*drug effects
Diarylheptanoids/*pharmacology
Glioblastoma/*drug therapy
Phosphatidylinositol 3-Kinase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Brain Neoplasms/enzymology ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Glioblastoma/enzymology ; Glioblastoma/pathology ; Humans ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/metabolism ; NF-kappa B/metabolism ; Neoplasm Invasiveness ; Signal Transduction ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Development of Antigen-specific Chimeric Antigen Receptor KHYG-1 Cells for Glioblastoma.
Autorzy :
Kang CH; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Kim Y; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.; Medicinal Chemistry and Pharmacology, Korea University of Science and Technology, Daejeon, Republic of Korea.
Lee SM; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Choi SU; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Park CH; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea; .; Medicinal Chemistry and Pharmacology, Korea University of Science and Technology, Daejeon, Republic of Korea.
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 1811-1819.
Typ publikacji :
Journal Article
MeSH Terms :
Immunotherapy, Adoptive*
Brain Neoplasms/*therapy
Glioblastoma/*therapy
Killer Cells, Natural/*immunology
Proto-Oncogene Proteins/*immunology
Proto-Oncogene Proteins c-met/*immunology
Receptor Protein-Tyrosine Kinases/*immunology
Receptors, Chimeric Antigen/*immunology
T-Lymphocytes/*immunology
Brain Neoplasms/immunology ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Coculture Techniques ; Cytokines/metabolism ; Cytotoxicity, Immunologic ; Folate Receptor 1/immunology ; Folate Receptor 1/metabolism ; Glioblastoma/immunology ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Jurkat Cells ; Killer Cells, Natural/metabolism ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-met/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism ; Receptors, Chimeric Antigen/genetics ; Receptors, Chimeric Antigen/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
MR imaging by 3D T1-weighted black blood sequences may improve delineation of therapy-naive high-grade gliomas.
Autorzy :
Finck T; Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany. .
Gempt J; Department of Neurosurgery, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Zimmer C; Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Kirschke JS; Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.; TUM-Neuroimaging Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Sollmann N; Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.; TUM-Neuroimaging Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
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Źródło :
European radiology [Eur Radiol] 2021 Apr; Vol. 31 (4), pp. 2312-2320. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Glioma*/diagnostic imaging
African Americans ; Aged ; Contrast Media ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Double cystic brain metastasis in a patient with stable pancreatic intraductal papillary mucinous neoplasm.
Autorzy :
Tardivo V; Dipartimento di Neurochirurgia, Città della Salute e della Scienza, Università di Torino, Torino, TO, Italy.
Vincitorio F; Dipartimento di Neurochirurgia, Città della Salute e della Scienza, Università di Torino, Torino, TO, Italy.
Monticelli M; Dipartimento di Neurochirurgia, Città della Salute e della Scienza, Università di Torino, Torino, TO, Italy.
Bertero L; Pathology Unit, Department of Medical Sciences, Università di Torino, Torino, TO, Italy.
Zenga F; Dipartimento di Neurochirurgia, Città della Salute e della Scienza, Università di Torino, Torino, TO, Italy.
Ducati A; Dipartimento di Neurochirurgia, Città della Salute e della Scienza, Università di Torino, Torino, TO, Italy.
Cassoni P; Pathology Unit, Department of Medical Sciences, Università di Torino, Torino, TO, Italy.
Garbossa D; Dipartimento di Neurochirurgia, Città della Salute e della Scienza, Università di Torino, Torino, TO, Italy.
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Źródło :
British journal of neurosurgery [Br J Neurosurg] 2021 Apr; Vol. 35 (2), pp. 236-240. Date of Electronic Publication: 2018 Mar 20.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Adenocarcinoma*
Adenocarcinoma, Mucinous*/diagnostic imaging
Adenocarcinoma, Mucinous*/surgery
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/surgery
Carcinoma, Pancreatic Ductal*/diagnosis
Carcinoma, Pancreatic Ductal*/surgery
Pancreatic Intraductal Neoplasms*
Pancreatic Neoplasms*/diagnostic imaging
Pancreatic Neoplasms*/surgery
Humans
Czasopismo naukowe
Tytuł :
Radiomics may increase the prognostic value for survival in glioblastoma patients when combined with conventional clinical and genetic prognostic models.
Autorzy :
Choi Y; Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Nam Y; Division of Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Gyeonggi-do, Republic of Korea. .
Jang J; Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Shin NY; Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Lee YS; Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ahn KJ; Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. .
Kim BS; Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Park JS; Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jeon SS; Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Hong YG; Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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Źródło :
European radiology [Eur Radiol] 2021 Apr; Vol. 31 (4), pp. 2084-2093. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/genetics
Humans ; Magnetic Resonance Imaging ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Human TERT promoter mutations as a prognostic biomarker in glioma.
Autorzy :
Powter B; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia. .
Jeffreys SA; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.
Sareen H; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.; Western Clinical School, University of New South Wales South, Goulburn St, Liverpool, NSW, 2170, Australia.
Cooper A; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.; Cancer Therapy Centre, Liverpool Hospital, Elizabeth St and Goulburn St, Liverpool, NSW, 2170, Australia.
Brungs D; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.; School of Medicine, University of Wollongong, Wollongong, NSW, 2522, Australia.
Po J; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.
Roberts T; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.; Western Clinical School, University of New South Wales South, Goulburn St, Liverpool, NSW, 2170, Australia.
Koh ES; Western Clinical School, University of New South Wales South, Goulburn St, Liverpool, NSW, 2170, Australia.; Cancer Therapy Centre, Liverpool Hospital, Elizabeth St and Goulburn St, Liverpool, NSW, 2170, Australia.
Scott KF; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.
Sajinovic M; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.
Vessey JY; Cancer Therapy Centre, Liverpool Hospital, Elizabeth St and Goulburn St, Liverpool, NSW, 2170, Australia.
de Souza P; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.; Western Clinical School, University of New South Wales South, Goulburn St, Liverpool, NSW, 2170, Australia.; Cancer Therapy Centre, Liverpool Hospital, Elizabeth St and Goulburn St, Liverpool, NSW, 2170, Australia.; School of Medicine, University of Wollongong, Wollongong, NSW, 2522, Australia.
Becker TM; Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, 2170, Australia.; School of Medicine, Western Sydney University, Campbelltown, NSW, 2560, Australia.; Western Clinical School, University of New South Wales South, Goulburn St, Liverpool, NSW, 2170, Australia.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Apr; Vol. 147 (4), pp. 1007-1017. Date of Electronic Publication: 2021 Feb 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mutation*
Biomarkers, Tumor/*genetics
Brain Neoplasms/*pathology
Glioma/*pathology
Telomerase/*genetics
Brain Neoplasms/genetics ; Brain Neoplasms/therapy ; Glioma/genetics ; Glioma/therapy ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.
Autorzy :
Yeini E; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ofek P; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Pozzi S; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Albeck N; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Sagol School of Neurosciences, Tel Aviv University, Tel Aviv, Israel.
Ben-Shushan D; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tiram G; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Golan S; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Kleiner R; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Sheinin R; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Israeli Dangoor S; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Reich-Zeliger S; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Grossman R; Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Ram Z; Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Brem H; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Hyde TM; Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.; Department of Psychiatry & Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Magod P; Department of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Sherman Building, Tel Aviv University, Tel Aviv, Israel.
Friedmann-Morvinski D; Sagol School of Neurosciences, Tel Aviv University, Tel Aviv, Israel.; Department of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Sherman Building, Tel Aviv University, Tel Aviv, Israel.
Madi A; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Satchi-Fainaro R; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. .; Sagol School of Neurosciences, Tel Aviv University, Tel Aviv, Israel. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1912. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms/*genetics
Glioblastoma/*genetics
Macrophages/*metabolism
Microglia/*metabolism
P-Selectin/*genetics
Animals ; Antineoplastic Agents/pharmacology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cells, Cultured ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic/drug effects ; Glioblastoma/drug therapy ; Glioblastoma/metabolism ; HEK293 Cells ; Humans ; Male ; Mice, Inbred C57BL ; Mice, SCID ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/genetics ; Neoplasms, Experimental/metabolism ; P-Selectin/antagonists & inhibitors ; P-Selectin/metabolism ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells.
Autorzy :
Huang T; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Yang Y; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Song X; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Wan X; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Wu B; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Sastry N; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Horbinski CM; Department of Pathology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Department of Neurological Surgery, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Zeng C; Department of Preventive Medicine, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Tiek D; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Goenka A; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Liu F; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin 53705, USA.
Brennan CW; Human Oncology and Pathogenesis Program, Department of Neurosurgery, Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Kessler JA; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Stupp R; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Department of Neurological Surgery, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Nakano I; Department of Neurosurgery, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Sulman EP; Department of Radiation Oncology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Nishikawa R; Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Saitama 350-1298, Japan.
James CD; Department of Neurological Surgery, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Zhang W; Department of Preventive Medicine, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Xu W; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin 53705, USA.
Hu B; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: .
Cheng SY; The Ken & Ruth Davee Department of Neurology, The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Mar 18; Vol. 81 (6), pp. 1276-1291.e9. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms*/genetics
Brain Neoplasms*/metabolism
Brain Neoplasms*/radiotherapy
Carcinogenesis*/genetics
Carcinogenesis*/metabolism
Carcinogenesis*/radiation effects
Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/metabolism
Glioblastoma*/genetics
Glioblastoma*/metabolism
Glioblastoma*/radiotherapy
Guanine Nucleotide Exchange Factors*/genetics
Guanine Nucleotide Exchange Factors*/metabolism
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Nuclear Proteins*/genetics
Nuclear Proteins*/metabolism
Protein-Arginine N-Methyltransferases*/genetics
Protein-Arginine N-Methyltransferases*/metabolism
Mitosis/*radiation effects
Animals ; Casein Kinase II/genetics ; Casein Kinase II/metabolism ; Cell Line, Tumor ; Female ; HEK293 Cells ; Humans ; Male ; Mice ; Mitosis/genetics ; Signal Transduction/genetics ; Signal Transduction/radiation effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
[The role of low grade glioma prognostic factors in therapeutic choices - summary of international literature and recommendations with conclusions].
Autorzy :
Szivos L; Idegsebészeti Tanszék, Debreceni Egyetem, Debrecen, Hungary. .
Virga J; Idegsebészeti Tanszék, Debreceni Egyetem, Debrecen, Hungary. .
Klekner Á; Idegsebészeti Tanszék, Debreceni Egyetem, Debrecen, Hungary. .
Árkosy P; Onkológiai Tanszék, Debreceni Egyetem, Debrecen, Hungary.
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Transliterated Title :
Az alacsony grádusú gliómák prognosztikai faktorainak szerepe a terápia megválasztásában – a nemzetközi irodalom és ajánlások összefoglalása konklúziókkal.
Źródło :
Magyar onkologia [Magy Onkol] 2021 Mar 17; Vol. 65 (1), pp. 59-70. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Glioma*/genetics
Glioma*/therapy
Humans ; Neoplasm Grading ; Prognosis
Czasopismo naukowe
Tytuł :
Maximal tumor diameter in the preoperative tumor magnetic resonance imaging (MRI) T2 image is associated with prognosis of Grade II Glioma.
Autorzy :
Liu H; Xiangya Hospital of Centre-south University, Changsha, Hunan, China.
Shen L
Huang X
Zhang G
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Mar 12; Vol. 100 (10), pp. e24850.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Magnetic Resonance Imaging*
Brain Neoplasms/*diagnostic imaging
Brain Neoplasms/*pathology
Glioma/*diagnostic imaging
Glioma/*pathology
Adult ; Brain Neoplasms/surgery ; Female ; Glioma/surgery ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Grading ; Preoperative Period ; Progression-Free Survival ; Proportional Hazards Models ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment.
Autorzy :
Rubio-Perez C; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Planas-Rigol E; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Trincado JL; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain.
Bonfill-Teixidor E; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Arias A; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Marchese D; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Moutinho C; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Serna G; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Pedrosa L; Hospital Clinic, University of Barcelona and Institut d'Investigacio Biomedica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Iurlaro R; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Martínez-Ricarte F; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.; Universitat Autònoma de Barcelona (UAB), 08193, Cerdanyola del Vallès, Spain.
Escudero L; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Cordero E; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.; Universitat Autònoma de Barcelona (UAB), 08193, Cerdanyola del Vallès, Spain.
Cicuendez M; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.; Universitat Autònoma de Barcelona (UAB), 08193, Cerdanyola del Vallès, Spain.
Ruiz S; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Parra G; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Nuciforo P; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.
Gonzalez J; Hospital Clinic, University of Barcelona and Institut d'Investigacio Biomedica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Pineda E; Hospital Clinic, University of Barcelona and Institut d'Investigacio Biomedica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Sahuquillo J; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.; Universitat Autònoma de Barcelona (UAB), 08193, Cerdanyola del Vallès, Spain.
Tabernero J; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain.; Universitat Autònoma de Barcelona (UAB), 08193, Cerdanyola del Vallès, Spain.; CIBERONC, Barcelona, Spain.
Heyn H; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. .; Universitat Pompeu Fabra (UPF), Barcelona, Spain. .
Seoane J; Vall d Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, 08035, Barcelona, Spain. .; Universitat Autònoma de Barcelona (UAB), 08193, Cerdanyola del Vallès, Spain. .; CIBERONC, Barcelona, Spain. .; Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010, Barcelona, Spain. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 08; Vol. 12 (1), pp. 1503. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukocytes*
Brain Neoplasms/*immunology
Cerebrospinal Fluid/*immunology
Tumor Microenvironment/*immunology
Adenocarcinoma of Lung ; Brain/pathology ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; CD8-Positive T-Lymphocytes/immunology ; Humans ; Immune Checkpoint Inhibitors ; Lung Neoplasms ; Prognosis
Czasopismo naukowe
Tytuł :
Staged Stereotactic Radiosurgery Decreases Symptomatic Radionecrosis in Large Brain Metastasis.
Autorzy :
Chevli N; Department of Radiation Oncology, University of Texas Medical Branch at Galveston, Galveston, TX, U.S.A.
Wang HC; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.
Dubey P; Department of Neuroradiology, Houston Methodist Hospital, Houston, TX, U.S.A.
Haque W; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.
Farach AM; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.
Pino R; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.
Rostomily RC; Department of Neurosurgery, Houston Methodist Hospital, Houston, TX, U.S.A.
Butler EB; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.
Teh BS; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.; .
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Źródło :
Anticancer research [Anticancer Res] 2021 Mar; Vol. 41 (3), pp. 1445-1449.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Dose Fractionation, Radiation*
Brain/*radiation effects
Brain Neoplasms/*radiotherapy
Radiosurgery/*methods
Adult ; Antineoplastic Agents, Immunological/therapeutic use ; Bevacizumab/therapeutic use ; Brain/drug effects ; Brain/pathology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/secondary ; Female ; Humans ; Necrosis/radiotherapy ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Circulating tumour DNA in patients with advanced melanoma treated with dabrafenib or dabrafenib plus trametinib: a clinical validation study.
Autorzy :
Syeda MM; NYU Langone Health, New York, NY, USA.
Wiggins JM; NYU Langone Health, New York, NY, USA.
Corless BC; NYU Langone Health, New York, NY, USA.
Long GV; Melanoma Institute Australia, The University of Sydney, Royal North Shore and Mater Hospitals, Sydney, NSW, Australia.
Flaherty KT; Dana-Farber Cancer Institute/Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Schadendorf D; University Hospital Essen, Essen, Germany; German Cancer Consortium, Heidelberg, Germany.
Nathan PD; East and North NHS Trust, Northwood, UK.
Robert C; Institute Gustave Roussy and Paris-Sud University, Villejuif, France.
Ribas A; Department of Medicine, Division of Hematology-Oncology, University of California, Los Angeles, Los Angeles, CA, USA.
Davies MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Grob JJ; Dermatology and Skin Cancer Department, Aix-Marseille University, Marseille, France.
Gasal E; Novartis Pharmaceuticals, East Hanover, NJ, USA.
Squires M; Novartis Institute for BioMedical Research, Cambridge, MA, USA.
Marker M; Novartis Pharmaceuticals, East Hanover, NJ, USA.
Garrett J; Novartis Pharmaceuticals, Cambridge, MA, USA.
Brase JC; Novartis Pharma, Basel, Switzerland.
Polsky D; NYU Langone Health, New York, NY, USA. Electronic address: .
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Źródło :
The Lancet. Oncology [Lancet Oncol] 2021 Mar; Vol. 22 (3), pp. 370-380. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Brain Neoplasms/*secondary
Circulating Tumor DNA/*genetics
Melanoma/*pathology
Aged ; Brain Neoplasms/drug therapy ; Brain Neoplasms/genetics ; Circulating Tumor DNA/analysis ; Double-Blind Method ; Female ; Follow-Up Studies ; Humans ; Imidazoles/administration & dosage ; Male ; Melanoma/drug therapy ; Melanoma/genetics ; Middle Aged ; Oximes/administration & dosage ; Prognosis ; Pyridones/administration & dosage ; Pyrimidinones/administration & dosage ; Survival Rate
Czasopismo naukowe
Tytuł :
Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependent.
Autorzy :
Haas B; Federal Institute for Drugs and Medical Devices, Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany. .
Ciftcioglu J; Federal Institute for Drugs and Medical Devices, Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany.; Faculty of Applied Natural Sciences, Cologne University of Applied Sciences, Kaiser-Wilhelm-Allee, 51368, Leverkusen, Germany.
Jermar S; Federal Institute for Drugs and Medical Devices, Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany.; Faculty of Applied Natural Sciences, Cologne University of Applied Sciences, Kaiser-Wilhelm-Allee, 51368, Leverkusen, Germany.
Weickhardt S; Federal Institute for Drugs and Medical Devices, Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany.
Eckstein N; Applied Pharmacy, University of Applied Sciences Kaiserslautern, Campus Pirmasens, Carl-Schurz-Str. 10-16, 66953, Pirmasens, Germany.
Kaina B; Institute of Toxicology, University Medical Center, Obere Zahlbacher Strasse 67, 55131, Mainz, Germany.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Mar; Vol. 147 (3), pp. 779-792. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
MeSH Terms :
Analgesics, Opioid/*pharmacology
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Brain Neoplasms/*drug therapy
Doxorubicin/*pharmacology
Glioblastoma/*drug therapy
Methadone/*pharmacology
Analgesics, Opioid/administration & dosage ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Doxorubicin/administration & dosage ; Drug Screening Assays, Antitumor ; Drug Synergism ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Methadone/administration & dosage ; Morphine/pharmacology ; Naloxone/pharmacology ; Oxycodone/pharmacology ; Receptors, Opioid, mu/agonists ; Receptors, Opioid, mu/antagonists & inhibitors ; Receptors, Opioid, mu/biosynthesis ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
The value of intravoxel incoherent motion imaging in predicting the survival of patients with astrocytoma.
Autorzy :
Zhu L; Department of Magnetic Resonance, Shanxi Cardiovascular Hospital, Taiyuan, Shanxi, PR China.
Wu J; Department of Magnetic Resonance, Shanxi Cardiovascular Hospital, Taiyuan, Shanxi, PR China.
Zhang H; Department of Magnetic Resonance, the First Hospital of Shanxi Medical University, Taiyuan, Shanxi, PR China.
Niu H; Department of Magnetic Resonance, Shanxi Cardiovascular Hospital, Taiyuan, Shanxi, PR China.
Wang L; Department of Magnetic Resonance, the First Hospital of Shanxi Medical University, Taiyuan, Shanxi, PR China.
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Źródło :
Acta radiologica (Stockholm, Sweden : 1987) [Acta Radiol] 2021 Mar; Vol. 62 (3), pp. 423-429. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytoma/*diagnostic imaging
Astrocytoma/*mortality
Brain Neoplasms/*diagnostic imaging
Brain Neoplasms/*mortality
Aged ; Astrocytoma/pathology ; Brain Neoplasms/pathology ; Cohort Studies ; Female ; Humans ; Kaplan-Meier Estimate ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; ROC Curve ; Survival Rate
Czasopismo naukowe
Tytuł :
Association between temporal muscle thickness and clinical outcomes in patients with newly diagnosed glioblastoma.
Autorzy :
An G; Department of Neurosurgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpodae-ro, Seocho-gu, Seoul, 06591, South Korea.
Ahn S; Department of Neurosurgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpodae-ro, Seocho-gu, Seoul, 06591, South Korea. .
Park JS; Department of Neurosurgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpodae-ro, Seocho-gu, Seoul, 06591, South Korea.
Jeun SS; Department of Neurosurgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpodae-ro, Seocho-gu, Seoul, 06591, South Korea.
Hong YK; Department of Neurosurgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpodae-ro, Seocho-gu, Seoul, 06591, South Korea.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Mar; Vol. 147 (3), pp. 901-909. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*pathology
Glioblastoma/*pathology
Temporal Muscle/*pathology
Adult ; Age Factors ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/analysis ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/surgery ; Female ; Glioblastoma/diagnostic imaging ; Glioblastoma/surgery ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Prognosis ; Propensity Score ; Retrospective Studies ; Survival Rate ; Temporal Muscle/diagnostic imaging ; Young Adult
Czasopismo naukowe
Tytuł :
miR-490 suppresses telomere maintenance program and associated hallmarks in glioblastoma.
Autorzy :
Vinchure OS; Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi, New Delhi, 110016, India.
Whittemore K; Telomeres and Telomerase Group, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, 28029, Madrid, Spain.
Kushwah D; Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi, New Delhi, 110016, India.
Blasco MA; Telomeres and Telomerase Group, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, 28029, Madrid, Spain.
Kulshreshtha R; Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi, New Delhi, 110016, India. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Mar; Vol. 78 (5), pp. 2299-2314. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Expression Regulation, Neoplastic*
Brain Neoplasms/*genetics
Glioblastoma/*genetics
MicroRNAs/*genetics
Telomere Homeostasis/*genetics
3' Untranslated Regions/genetics ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/metabolism ; SOXB1 Transcription Factors/genetics ; SOXB1 Transcription Factors/metabolism ; SOXC Transcription Factors/genetics ; SOXC Transcription Factors/metabolism ; Tankyrases/genetics ; Tankyrases/metabolism ; Telomeric Repeat Binding Protein 2/genetics ; Telomeric Repeat Binding Protein 2/metabolism
Czasopismo naukowe

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