Autor: "Brattås PL" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: LINE-2 transposable elements are a source of functional human microRNAs and target sites.
Autorzy:: Petri R; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden.
Brattås PL; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden.
Sharma Y; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden.
Jönsson ME; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden.
Pircs K; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden.
Bengzon J; Department of Clinical Sciences, Division of Neurosurgery, Lund Stem Cell Center, Lund University and Region Skåne, Lund, Sweden.
Jakobsson J; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2019 Mar 13; Vol. 15 (3), pp. e1008036. Date of Electronic Publication: 2019 Mar 13 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Transposable Elements*
Long Interspersed Nucleotide Elements*
MicroRNAs/*genetics
3' Untranslated Regions ; Animals ; Argonaute Proteins/genetics ; Argonaute Proteins/metabolism ; Base Sequence ; Brain/metabolism ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Gene Expression Regulation ; Gene Regulatory Networks ; Genome, Human ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Humans ; Mice ; MicroRNAs/metabolism

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Skocz do pozycji: 2.

Tytuł:: Identification of Multiple QTLs Linked to Neuropathology in the Engrailed-1 Heterozygous Mouse Model of Parkinson's Disease.
Autorzy:: Kurowska Z; Neurodegeneration and Inflammation Genetics Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, Sölvegatan 17, 221 84 Lund, Sweden.; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.; Renovo Neural Inc., 10000 Cedar Avenue, Cleveland 44106, OH, USA.
Jewett M; Neurodegeneration and Inflammation Genetics Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, Sölvegatan 17, 221 84 Lund, Sweden.
Brattås PL; Neurodegeneration and Inflammation Genetics Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, Sölvegatan 17, 221 84 Lund, Sweden.
Jimenez-Ferrer I; Neurodegeneration and Inflammation Genetics Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, Sölvegatan 17, 221 84 Lund, Sweden.
Kenéz X; Neurodegeneration and Inflammation Genetics Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, Sölvegatan 17, 221 84 Lund, Sweden.
Björklund T; Molecular Neuromodulation Unit, Lund University, Biomedical Center A10, Sölvegatan 17, 221 84 Lund, Sweden.
Nordström U; Department of Pharmacology and Clinical Neuroscience, Byggnad 6M NUS, Umeå University, 901 87 Umeå, Sweden.
Brundin P; Laboratory of Translational Parkinson's Disease Research, Center for Neurodegenerative Science, Van Andel Research Institute, 333 Bostwick Ave, N.E., Grand Rapids, MI 49503, USA.
Swanberg M; Neurodegeneration and Inflammation Genetics Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, Sölvegatan 17, 221 84 Lund, Sweden.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Aug 23; Vol. 6, pp. 31701. Date of Electronic Publication: 2016 Aug 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Disease Models, Animal*
Homeodomain Proteins/*genetics
Parkinson Disease/*genetics
Quantitative Trait Loci/*genetics
Animals ; Dopaminergic Neurons/metabolism ; Female ; Genetic Predisposition to Disease/genetics ; Heterozygote ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Neurodegenerative Diseases/genetics ; Neuropathology ; Substantia Nigra/metabolism ; Substantia Nigra/pathology

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Skocz do pozycji: 3.

Tytuł:: Distinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs in hippocampal neurons.
Autorzy:: Malmevik J; Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, Sölvegatan 17, 221 84 Lund, Sweden.
Petri R; Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, Sölvegatan 17, 221 84 Lund, Sweden.
Knauff P; Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, Sölvegatan 17, 221 84 Lund, Sweden.
Brattås PL; Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, Sölvegatan 17, 221 84 Lund, Sweden.
Åkerblom M; Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, Sölvegatan 17, 221 84 Lund, Sweden.
Jakobsson J; Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, Sölvegatan 17, 221 84 Lund, Sweden.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Jan 27; Vol. 6, pp. 19879. Date of Electronic Publication: 2016 Jan 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cognition*
Transcriptome*
MicroRNAs/*genetics
Pyramidal Cells/*metabolism
Animals ; Cells, Cultured ; Dependovirus/genetics ; Gene Expression ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Order ; Genetic Vectors/administration & dosage ; Genetic Vectors/genetics ; Hippocampus/cytology ; Hippocampus/metabolism ; Male ; Mice ; Mice, Transgenic ; RNA Interference ; Signal Transduction

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Tytuł:: The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.
Autorzy:: Sandén C; Department of Hematology, Lund University, BMC B13, Klinikgatan 26, 221 84 Lund, Sweden. .
Järvstråt L
Lennartsson A
Brattås PL
Nilsson B
Gullberg U; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2014 Sep 12; Vol. 13, pp. 215. Date of Electronic Publication: 2014 Sep 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation*
Transcription, Genetic*
Chromatin/*genetics
Chromosomal Proteins, Non-Histone/*genetics
Chromosomal Proteins, Non-Histone/*metabolism
Myeloid Cells/*metabolism
Oncogene Proteins/*genetics
Oncogene Proteins/*metabolism
Binding Sites ; Cells, Cultured ; Chromatin/metabolism ; DNA Methylation ; Epigenesis, Genetic ; Gene Expression Profiling ; Genome, Human ; Histones/metabolism ; Humans ; Poly-ADP-Ribose Binding Proteins ; Promoter Regions, Genetic ; RNA Polymerase II/metabolism ; Sequence Analysis, DNA

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