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Tytuł :
Immune deserts in head and neck squamous cell carcinoma: A review of challenges and opportunities for modulating the tumor immune microenvironment.
Autorzy :
Farlow JL; Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Brenner JC; Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.
Lei YL; Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA; Department of Periodontics and Oral Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Chinn SB; Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA. Electronic address: .
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Źródło :
Oral oncology [Oral Oncol] 2021 Sep; Vol. 120, pp. 105420. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
SearcHPV: A novel approach to identify and assemble human papillomavirus-host genomic integration events in cancer.
Autorzy :
Pinatti LM; Cancer Biology Program, Program in the Biomedical Sciences, Rackham Graduate School, University of Michigan, Ann Arbor, Michigan.; Department of Otolaryngology/Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan.
Gu W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.
Wang Y; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan.
Elhossiny A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.
Bhangale AD; Department of Otolaryngology/Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan.
Brummel CV; Department of Otolaryngology/Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan.
Carey TE; Cancer Biology Program, Program in the Biomedical Sciences, Rackham Graduate School, University of Michigan, Ann Arbor, Michigan.; Department of Otolaryngology/Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, Michigan.; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan.
Mills RE; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan.
Brenner JC; Department of Otolaryngology/Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, Michigan.; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan.
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Źródło :
Cancer [Cancer] 2021 Oct 01; Vol. 127 (19), pp. 3531-3540. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Implementation of human papillomavirus circulating tumor DNA to identify recurrence during treatment de-escalation.
Autorzy :
Haring CT; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Brummel C; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Bhambhani C; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States.
Jewell B; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Neal MH; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Bhangale A; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Casper K; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Malloy K; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
McLean S; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Shuman A; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Stucken C; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Rosko A; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Prince M; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Bradford C; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Eisbruch A; University of Michigan, Department of Radiation Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Mierzwa M; University of Michigan, Department of Radiation Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Tewari M; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Worden FP; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Swiecicki PL; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Spector ME; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Brenner JC; University of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States; University of Michigan, Department of Pharmacology, United States. Electronic address: .
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Źródło :
Oral oncology [Oral Oncol] 2021 Oct; Vol. 121, pp. 105332. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma.
Autorzy :
Haring CT; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.; Co-First Authors.
Bhambhani C; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, Ann Arbor, MI 48109, USA.; Co-First Authors.
Brummel C; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.
Jewell B; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.
Bellile E; University of Michigan, Department of Biostatistics, Ann Arbor, MI 48109, USA.
Heft Neal ME; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.
Sandford E; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, Ann Arbor, MI 48109, USA.
Spengler RM; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, Ann Arbor, MI 48109, USA.
Bhangale A; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.
Spector ME; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.; University of Michigan, Rogel Cancer Center, Ann Arbor, MI 48109, USA.
McHugh J; University of Michigan, Rogel Cancer Center, Ann Arbor, MI 48109, USA.; University of Michigan, Department of Pathology, Ann Arbor, MI 48109, USA.
Prince ME; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.
Mierzwa M; University of Michigan, Rogel Cancer Center, Ann Arbor, MI 48109, USA.; University of Michigan, Department of Radiation Oncology, Ann Arbor, MI 48109, USA.
Worden FP; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, Ann Arbor, MI 48109, USA.; University of Michigan, Rogel Cancer Center, Ann Arbor, MI 48109, USA.
Tewari M; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, Ann Arbor, MI 48109, USA.; University of Michigan, Rogel Cancer Center, Ann Arbor, MI 48109, USA.; University of Michigan, Department of Biomedical Engineering, Ann Arbor, MI 48109, USA.; University of Michigan, Center for Computational Medicine and Bioinformatics, Ann Arbor, MI 48109, USA.; Co-Senior Authors.
Swiecicki PL; University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, Ann Arbor, MI 48109, USA.; University of Michigan, Rogel Cancer Center, Ann Arbor, MI 48109, USA.; Co-Senior Authors.
Brenner JC; University of Michigan, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, MI 48109, USA.; University of Michigan, Rogel Cancer Center, Ann Arbor, MI 48109, USA.; University of Michigan, Department of Pharmacology, Ann Arbor, MI 48109, USA.; Co-Senior Authors.
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Źródło :
Oncotarget [Oncotarget] 2021 Jun 22; Vol. 12 (13), pp. 1214-1229. Date of Electronic Publication: 2021 Jun 22 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Integrative sequencing discovers an ATF1-motif enriched molecular signature that differentiates hyalinizing clear cell carcinoma from mucoepidemoid carcinoma.
Autorzy :
Heft Neal ME; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States.
Gensterblum-Miller E; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States.
Bhangale AD; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States.
Kulkarni A; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States.
Zhai J; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, United States.
Smith J; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States.
Brummel C; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States.
Foltin SK; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States.
Thomas D; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, United States.
Jiang H; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, United States; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, United States.
McHugh JB; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, United States.
Brenner JC; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, United States; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, United States; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address: .
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Źródło :
Oral oncology [Oral Oncol] 2021 Jun; Vol. 117, pp. 105270. Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Genetic analysis of sinonasal undifferentiated carcinoma discovers recurrent SWI/SNF alterations and a novel PGAP3-SRPK1 fusion gene.
Autorzy :
Heft Neal ME; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Birkeland AC; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Bhangale AD; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Zhai J; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
Kulkarni A; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Foltin SK; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Jewell BM; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Ludwig ML; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Program in Cellular and Molecular Biology, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Pinatti L; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Program in Cancer Biology, University of Michigan, Ann Arbor, MI, USA.
Jiang H; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
McHugh JB; Rogel Cancer Center, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Marentette L; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Rogel Cancer Center, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
McKean EL; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Rogel Cancer Center, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Brenner JC; Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA. .; Program in Cellular and Molecular Biology, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA. .; Rogel Cancer Center, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA. .; Department of Pharmacology, University of Michigan, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA. .
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Źródło :
BMC cancer [BMC Cancer] 2021 May 29; Vol. 21 (1), pp. 636. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Homeowner perceptions and responses to buffelgrass invasion risk in the Tucson, Arizona Wildland-Urban Interface.
Autorzy :
Plecki AF; Forestry Program, Southern Illinois University, Carbondale, IL, USA.
Akamani K; Forestry Program, Southern Illinois University, Carbondale, IL, USA.
Groninger JW; Forestry Program, Southern Illinois University, Carbondale, IL, USA.
Brenner JC; Department of Environmental Studies and Sciences, Ithaca College, Ithaca, NY, USA.
Gage KL; Plant, Soils, and Agricultural Systems/Plant Biology Program, Southern Illinois University, Carbondale, IL, USA.
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Źródło :
Heliyon [Heliyon] 2021 May 27; Vol. 7 (5), pp. e07040. Date of Electronic Publication: 2021 May 27 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Tumor-Infiltrating Lymphocytes in Patients With Advanced Laryngeal Cancer Undergoing Bioselection.
Autorzy :
Heft Neal ME; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Smith JD; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Birkeland AC; Department of Otolaryngology-Head and Neck Surgery, University of California Davis, Sacramento, California, USA.
Haring CT; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Chinn SB; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Shuman AG; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Casper KA; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Malloy KM; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Stucken CL; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Mclean SA; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Rosko AJ; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Mierzwa ML; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
Shah J; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
Schonewolf C; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
Swiecicki PL; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Worden FP; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Wolf GT; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Bradford CR; Department of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Prince MEP; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Brenner JC; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Spector ME; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
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Źródło :
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 2021 May 25, pp. 1945998211013765. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Surveillance and Monitoring Techniques for HPV-Related Head and Neck Squamous Cell Carcinoma: Circulating Tumor DNA.
Autorzy :
Dermody SM; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Health System, Ann Arbor, MI, USA.
Haring CT; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Health System, Ann Arbor, MI, USA.
Bhambhani C; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Medical School, Ann Arbor, MI, USA.
Tewari M; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Internal Medicine, Division of Hematology/Oncology, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI, USA.
Brenner JC; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Health System, Ann Arbor, MI, USA.
Swiecicki PL; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Medical School, Ann Arbor, MI, USA. .; Department of Internal Medicine, Division of Hematology/Oncology, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI, USA. .
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Źródło :
Current treatment options in oncology [Curr Treat Options Oncol] 2021 Feb 08; Vol. 22 (3), pp. 21. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Efficacy of axitinib in metastatic head and neck cancer with novel radiographic response criteria.
Autorzy :
Swiecicki PL; Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.; Division of Hematology/Oncology, Department of Internal Medicine, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan.
Bellile EL; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan.
Brummel CV; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, University of Michigan Health System, Ann Arbor, Michigan.
Brenner JC; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan.; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, University of Michigan Health System, Ann Arbor, Michigan.
Worden FP; Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan.
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Źródło :
Cancer [Cancer] 2021 Jan 15; Vol. 127 (2), pp. 219-228. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Axitinib/*administration & dosage
Head and Neck Neoplasms/*drug therapy
Head and Neck Neoplasms/*mortality
Protein Kinase Inhibitors/*administration & dosage
Squamous Cell Carcinoma of Head and Neck/*drug therapy
Squamous Cell Carcinoma of Head and Neck/*mortality
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Female ; Head and Neck Neoplasms/diagnostic imaging ; Head and Neck Neoplasms/metabolism ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis/diagnostic imaging ; Neoplasm Metastasis/drug therapy ; Neoplasm Recurrence, Local/drug therapy ; Phosphatidylinositol 3-Kinases/metabolism ; Receptors, Vascular Endothelial Growth Factor/antagonists & inhibitors ; Signal Transduction/drug effects ; Squamous Cell Carcinoma of Head and Neck/diagnostic imaging ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Survival Rate ; Tomography, X-Ray Computed/methods ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Prognostic Significance of Oxidation Pathway Mutations in Recurrent Laryngeal Squamous Cell Carcinoma.
Autorzy :
Heft Neal ME; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Bhangale AD; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Birkeland AC; Department of Otolaryngology-Head and Neck Surgery, University of California Davis, Sacramento, CA 95817, USA.
McHugh JB; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Shuman AG; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Rosko AJ; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Swiecicki PL; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Spector ME; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Brenner JC; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
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Źródło :
Cancers [Cancers (Basel)] 2020 Oct 22; Vol. 12 (11). Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A multi-center phase II trial evaluating the efficacy of palbociclib in combination with carboplatin for the treatment of unresectable recurrent or metastatic head and neck squamous cell carcinoma.
Autorzy :
Swiecicki PL; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Medical School, 300 N Ingalls St, SPC 5419, Ann Arbor, MI, 48109, USA. .; Department of Internal Medicine, Division of Hematology/Oncology, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI, USA. .; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA. .
Durm G; Department of Internal Medicine, Division of Hematology/Oncology, Indiana University, Indianapolis, IN, USA.
Bellile E; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Bhangale A; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, University of Michigan Health System, Ann Arbor, MI, USA.
Brenner JC; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, University of Michigan Health System, Ann Arbor, MI, USA.; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, USA.
Worden FP; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Medical School, 300 N Ingalls St, SPC 5419, Ann Arbor, MI, 48109, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA.
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Źródło :
Investigational new drugs [Invest New Drugs] 2020 Oct; Vol. 38 (5), pp. 1550-1558. Date of Electronic Publication: 2020 Jan 24.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Carboplatin/*administration & dosage
Head and Neck Neoplasms/*drug therapy
Piperazines/*administration & dosage
Protein Kinase Inhibitors/*administration & dosage
Pyridines/*administration & dosage
Squamous Cell Carcinoma of Head and Neck/*drug therapy
Adult ; Aged ; Antineoplastic Agents/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Carboplatin/adverse effects ; Female ; Head and Neck Neoplasms/mortality ; Head and Neck Neoplasms/pathology ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Piperazines/adverse effects ; Protein Kinase Inhibitors/adverse effects ; Pyridines/adverse effects ; Squamous Cell Carcinoma of Head and Neck/mortality ; Squamous Cell Carcinoma of Head and Neck/pathology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Overexpression of Sal-like protein 4 in head and neck cancer: epigenetic effects and clinical correlations.
Autorzy :
Misawa K; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan. .
Misawa Y; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan.
Mima M; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan.; Department of Molecular Oncology, Chiba University, Chiba, Japan.
Yamada S; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan.; Preeminent Medical Photonics Education & Research Center Institute for NanoSuit Research, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Imai A; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan.
Mochizuki D; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan.
Nakagawa T; Department of Molecular Oncology, Chiba University, Chiba, Japan.
Kurokawa T; Department of Molecular Oncology, Chiba University, Chiba, Japan.
Endo S; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan.
Kawasaki H; Preeminent Medical Photonics Education & Research Center Institute for NanoSuit Research, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Brenner JC; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Health System, Ann Arbor, MI, USA.
Mineta H; Department of Otolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Shizuoka, 431-3192, Japan.
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Źródło :
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2020 Aug; Vol. 43 (4), pp. 631-641. Date of Electronic Publication: 2020 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Head and Neck Neoplasms/*metabolism
Head and Neck Neoplasms/*pathology
Squamous Cell Carcinoma of Head and Neck/*metabolism
Squamous Cell Carcinoma of Head and Neck/*pathology
Transcription Factors/*metabolism
Adult ; Aged ; Biomarkers, Tumor/metabolism ; Cell Proliferation/physiology ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; Disease-Free Survival ; Epigenesis, Genetic ; Female ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; Male ; Middle Aged ; Up-Regulation
Czasopismo naukowe
Tytuł :
"My Research Is Their Business, but I'm Not Their Business": Patient and Clinician Perspectives on Commercialization of Precision Oncology Data.
Autorzy :
Spector-Bagdady K; Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Center for Bioethics & Social Sciences in Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Krenz CD; Center for Bioethics & Social Sciences in Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Brummel C; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Brenner JC; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Bradford CR; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Shuman AG; Center for Bioethics & Social Sciences in Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.
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Źródło :
The oncologist [Oncologist] 2020 Jul; Vol. 25 (7), pp. 620-626. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Medical Oncology*
Precision Medicine*
Adult ; Humans ; Informed Consent ; Motivation ; Prospective Studies
Czasopismo naukowe
Tytuł :
Predictors of survival in patients undergoing oropharyngeal surgery for cancer recurrence after radiation therapy.
Autorzy :
Heft Neal ME; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA. .
Brennan J; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Haring CT; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Brenner JC; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Worden F; Department of Internal Medicine, Medical Oncology, University of Michigan, Ann Arbor, MI, USA.
Swiecicki P; Department of Internal Medicine, Medical Oncology, University of Michigan, Ann Arbor, MI, USA.
Mierzwa M; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Casper KA; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Malloy KM; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Stucken CL; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
McLean SA; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Prince ME; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Bradford CR; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Wolf GT; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Shuman AG; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Chinn SB; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Chepeha DB; Department of Otolaryngology Head and Neck Surgery, University of Toronto, Toronto, ON, Canada.
Rosko AJ; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Spector ME; Department of Otolaryngology Head and Neck Surgery, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
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Źródło :
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2020 Jul; Vol. 277 (7), pp. 2085-2093. Date of Electronic Publication: 2020 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Squamous Cell*/radiotherapy
Carcinoma, Squamous Cell*/surgery
Head and Neck Neoplasms*
Oropharyngeal Neoplasms*/radiotherapy
Oropharyngeal Neoplasms*/surgery
Humans ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies ; Salvage Therapy ; Survival Rate
Czasopismo naukowe
Tytuł :
Speech and swallowing outcomes after laryngectomy for the dysfunctional irradiated larynx.
Autorzy :
Farlow JL; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Birkeland AC; Department of Otolaryngology, Head and Neck Surgery, University of California Davis, Sacramento, CA, 98517, USA.
Hardenbergh A; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Lyden T; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Brenner JC; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Shuman AG; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Chinn SB; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Stucken CL; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Malloy KM; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Moyer JS; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Casper KA; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Prince MEP; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Bradford CR; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Wolf GT; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA.
Chepeha DB; Department of Otolaryngology, University of Toronto, Toronto, ON, Canada.
Rosko AJ; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA. .
Spector ME; Department of Otolaryngology, Head and Neck Surgery, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5312, USA. .
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Źródło :
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2020 May; Vol. 277 (5), pp. 1459-1465. Date of Electronic Publication: 2020 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Laryngeal Neoplasms*/radiotherapy
Laryngeal Neoplasms*/surgery
Larynx*
Deglutition ; Humans ; Laryngectomy ; Retrospective Studies ; Speech
Czasopismo naukowe
Tytuł :
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.
Autorzy :
Luo X; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Donnelly CR; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; Oral Health Sciences PhD Program, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Gong W; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Heath BR; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Hao Y; Department of Computational Mathematics, Science, and Engineering, Michigan State University, East Lansing, Michigan, USA.
Donnelly LA; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Moghbeli T; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Tan YS; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.
Lin X; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Bellile E; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.
Kansy BA; Department of Otolaryngology, University Hospital Essen, Essen, North Rhine-Westphalia, Germany.
Carey TE; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.; Department of Otolaryngology-Head and Neck Surgery.
Brenner JC; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.; Department of Otolaryngology-Head and Neck Surgery.
Cheng L; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Polverini PJ; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; Oral Health Sciences PhD Program, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.; Department of Pathology, and.
Morgan MA; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, Michigan, USA.
Wen H; Department of Microbial Infection and Immunity, Ohio State University College of Medicine, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Prince ME; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.; Department of Otolaryngology-Head and Neck Surgery.
Ferris RL; Department of Otolaryngology, Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Xie Y; Department of Computational Mathematics, Science, and Engineering, Michigan State University, East Lansing, Michigan, USA.
Young S; Department of Oral & Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Wolf GT; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.; Department of Otolaryngology-Head and Neck Surgery.
Chen Q; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Lei YL; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; Oral Health Sciences PhD Program, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.; Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, USA.; Department of Otolaryngology-Head and Neck Surgery.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2020 Apr 01; Vol. 130 (4), pp. 1635-1652.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteolysis*
Tumor Escape*
Head and Neck Neoplasms/*immunology
Human papillomavirus 16/*immunology
Membrane Proteins/*immunology
Mitochondrial Proteins/*immunology
Squamous Cell Carcinoma of Head and Neck/*immunology
Animals ; Cell Line, Tumor ; Female ; Head and Neck Neoplasms/genetics ; Head and Neck Neoplasms/virology ; Human papillomavirus 16/genetics ; Humans ; Male ; Membrane Proteins/genetics ; Mice ; Mice, Knockout ; Mitochondrial Proteins/genetics ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/immunology ; Signal Transduction/genetics ; Signal Transduction/immunology ; Squamous Cell Carcinoma of Head and Neck/genetics ; Squamous Cell Carcinoma of Head and Neck/virology
Czasopismo naukowe
Tytuł :
Rationale for the advancement of PI3K pathway inhibitors for personalized chordoma therapy.
Autorzy :
Michmerhuizen NL; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, USA.
Owen JH; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Heft Neal ME; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Mann JE; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Leonard E; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.
Wang J; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, USA.
Zhai J; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Jiang H; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA.
McHugh JB; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA.
Brenner JC; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA. .; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, USA. .; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA. .
Prince MEP; Department of Otolaryngology - Head and Neck Surgery, University of Michigan Medical School, 1150 E. Medical Center Dr., 9301B MSRB3, Ann Arbor, MI, 48109-0602, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA.
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2020 Mar; Vol. 147 (1), pp. 25-35. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Chordoma/*metabolism
Phosphatidylinositol 3-Kinase/*metabolism
Phosphoinositide-3 Kinase Inhibitors/*administration & dosage
Precision Medicine/*methods
Signal Transduction/*drug effects
Aminopyridines/administration & dosage ; Animals ; Cell Line, Tumor ; Chordoma/drug therapy ; Humans ; Mice ; Morpholines/administration & dosage ; Proto-Oncogene Proteins c-akt/metabolism ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe

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