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Tytuł:
Radiosensitivity of cancer-initiating cells and normal stem cells (or what the Heisenberg uncertainly principle has to do with biology)
Autorzy:
Woodward WA
Bristow RG
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Źródło:
Seminars in Radiation Oncology; Apr2009, Vol. 19 Issue 2, p87-95, 9p
Czasopismo naukowe
Szczegóły
Tytuł:
Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation.
Autorzy:
Grosset AA; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Department of Pathology and Cellular Biology, Université de Montréal, Montreal, Quebec, Canada.
Dallaire F; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Department of Computer Engineering and Software Engineering, Polytechnique Montréal, Montreal, Quebec, Canada.
Nguyen T; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Department of Engineering Physics, Polytechnique Montréal, Montreal, Quebec, Canada.
Birlea M; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.
Wong J; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.
Daoust F; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Department of Engineering Physics, Polytechnique Montréal, Montreal, Quebec, Canada.
Roy N; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.
Kougioumoutzakis A; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.
Azzi F; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.
Aubertin K; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.
Kadoury S; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Department of Computer Engineering and Software Engineering, Polytechnique Montréal, Montreal, Quebec, Canada.
Latour M; Department of Pathology and Cellular Biology, Université de Montréal, Montreal, Quebec, Canada.; Department of Pathology, Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Albadine R; Department of Pathology and Cellular Biology, Université de Montréal, Montreal, Quebec, Canada.; Department of Pathology, Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Prendeville S; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.
Boutros P; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.; Department of Urology, University of California, Los Angeles, Los Angeles, California, United States of America.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, California, United States of America.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California, United States of America.
Fraser M; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Bristow RG; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
van der Kwast T; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Orain M; Oncology Division, Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Quebec City, Quebec, Canada.; Centre de recherche sur le cancer, Université Laval, Quebec City, Quebec, Canada.
Brisson H; Oncology Division, Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Quebec City, Quebec, Canada.; Centre de recherche sur le cancer, Université Laval, Quebec City, Quebec, Canada.
Benzerdjeb N; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Oncology Division, Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Quebec City, Quebec, Canada.; Centre de recherche sur le cancer, Université Laval, Quebec City, Quebec, Canada.
Hovington H; Oncology Division, Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Quebec City, Quebec, Canada.; Centre de recherche sur le cancer, Université Laval, Quebec City, Quebec, Canada.
Bergeron A; Oncology Division, Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Quebec City, Quebec, Canada.; Centre de recherche sur le cancer, Université Laval, Quebec City, Quebec, Canada.; Department of Surgery, Université Laval, Quebec City, Quebec, Canada.
Fradet Y; Oncology Division, Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Quebec City, Quebec, Canada.; Centre de recherche sur le cancer, Université Laval, Quebec City, Quebec, Canada.; Department of Surgery, Université Laval, Quebec City, Quebec, Canada.
Têtu B; Oncology Division, Centre de recherche du Centre hospitalier universitaire de Québec-Université Laval, Quebec City, Quebec, Canada.; Centre de recherche sur le cancer, Université Laval, Quebec City, Quebec, Canada.
Saad F; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.
Leblond F; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Department of Engineering Physics, Polytechnique Montréal, Montreal, Quebec, Canada.
Trudel D; Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; Institut du cancer de Montréal, Montreal, Quebec, Canada.; Department of Pathology and Cellular Biology, Université de Montréal, Montreal, Quebec, Canada.; Department of Pathology, Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
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Źródło:
PLoS medicine [PLoS Med] 2020 Aug 14; Vol. 17 (8), pp. e1003281. Date of Electronic Publication: 2020 Aug 14 (Print Publication: 2020).
Typ publikacji:
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Intraductal, Noninfiltrating/*diagnostic imaging
Machine Learning/*standards
Nonlinear Optical Microscopy/*standards
Prostatic Neoplasms/*diagnostic imaging
Aged ; Canada/epidemiology ; Carcinoma, Intraductal, Noninfiltrating/epidemiology ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Case-Control Studies ; Cohort Studies ; Humans ; Male ; Middle Aged ; Nonlinear Optical Microscopy/methods ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/pathology ; Reproducibility of Results ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Valection: design optimization for validation and verification studies.
Autorzy:
Cooper CI; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.
Yao D; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.
Sendorek DH; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.
Yamaguchi TN; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.
P'ng C; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.
Houlahan KE; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.
Caloian C; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.
Fraser M; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
Ellrott K; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA.; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.
Margolin AA; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA.; Sage Bionetworks, Seattle, WA, USA.
Bristow RG; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
Stuart JM; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.
Boutros PC; Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada. .; Department of Medical Biophysics, University of Toronto, Toronto, Canada. .; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada. .; Departments of Human Genetics & Urology, University of California, Los Angeles, USA. .; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, USA. .; Institute for Precision Health, University of California, Los Angeles, USA. .
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Corporate Authors:
SMC-DNA Challenge Participants
Źródło:
BMC bioinformatics [BMC Bioinformatics] 2018 Sep 25; Vol. 19 (1), pp. 339. Date of Electronic Publication: 2018 Sep 25.
Typ publikacji:
Journal Article
MeSH Terms:
Software Validation*
Sequence Analysis, DNA/*methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations.
Autorzy:
Böttcher R; Department of Urology, Erasmus MC, Rotterdam, the Netherlands.
Kweldam CF; Department of Pathology, Erasmus University Medical Center, Josephine Nefkens Institute building, Be-222, P.O. Box 2040, Rotterdam, 3000 CA, The Netherlands.
Livingstone J; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Lalonde E; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Yamaguchi TN; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Huang V; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Yousif F; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.
Fraser M; Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Bristow RG; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
van der Kwast T; Department of Pathology and Laboratory Medicine, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
Boutros PC; Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.
Jenster G; Department of Urology, Erasmus MC, Rotterdam, the Netherlands.
van Leenders GJLH; Department of Pathology, Erasmus University Medical Center, Josephine Nefkens Institute building, Be-222, P.O. Box 2040, Rotterdam, 3000 CA, The Netherlands. .
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Źródło:
BMC cancer [BMC Cancer] 2018 Jan 02; Vol. 18 (1), pp. 8. Date of Electronic Publication: 2018 Jan 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Copy Number Variations*
Genomic Instability*
Adenocarcinoma/*genetics
Biomarkers, Tumor/*genetics
Carcinoma, Intraductal, Noninfiltrating/*genetics
Genomics/*methods
Prostatic Neoplasms/*genetics
Adenocarcinoma/pathology ; Aged ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Prognosis ; Prostatic Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Combined Treatment with Ionizing Radiation and the PARP Inhibitor Olaparib in BRCA Mutant and Wild Type Patient-Derived Pancreatic Cancer Xenografts.
Autorzy:
Lohse I; Ontario Cancer Institute and Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Kumareswaran R; Ontario Cancer Institute and Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Cao P; Ontario Cancer Institute and Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Pitcher B; Ontario Cancer Institute and Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Gallinger S; Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada.; Translational Research Initiative in Pancreas Cancer, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Bristow RG; Ontario Cancer Institute and Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Hedley DW; Ontario Cancer Institute and Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Department of Medical Oncology and Haematology, Princess Margaret Cancer Center, Toronto, Ontario, Canada.
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Źródło:
PloS one [PLoS One] 2016 Dec 29; Vol. 11 (12), pp. e0167272. Date of Electronic Publication: 2016 Dec 29 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
BRCA2 Protein/*genetics
Pancreatic Neoplasms/*drug therapy
Pancreatic Neoplasms/*radiotherapy
Phthalazines/*therapeutic use
Piperazines/*therapeutic use
Poly(ADP-ribose) Polymerase Inhibitors/*therapeutic use
Xenograft Model Antitumor Assays/*methods
Animals ; Antineoplastic Agents/therapeutic use ; Cell Proliferation/drug effects ; Cell Proliferation/radiation effects ; Combined Modality Therapy/methods ; Humans ; Mice ; Mice, SCID ; Pancreatic Neoplasms/genetics ; Radiation, Ionizing ; Radiation-Sensitizing Agents/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 48

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