- Tytuł:
- 1-Methyl-D-tryptophan activates aryl hydrocarbon receptor, a pathway associated with bladder cancer progression.
- Autorzy:
- Źródło:
- BMC cancer [BMC Cancer] 2020 Sep 09; Vol. 20 (1), pp. 869. Date of Electronic Publication: 2020 Sep 09.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Basic Helix-Loop-Helix Transcription Factors/*genetics
Indoleamine-Pyrrole 2,3,-Dioxygenase/*genetics
Receptors, Aryl Hydrocarbon/*genetics
Tryptophan/*analogs & derivatives
Urinary Bladder Neoplasms/*drug therapy
Aged ; Basic Helix-Loop-Helix Transcription Factors/antagonists & inhibitors ; Basic Helix-Loop-Helix Transcription Factors/blood ; Cell Line, Tumor ; Cytochrome P-450 CYP1A1/blood ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1A2/blood ; Cytochrome P-450 CYP1A2/genetics ; Cytochrome P-450 CYP1B1/blood ; Cytochrome P-450 CYP1B1/genetics ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunotherapy ; Indoleamine-Pyrrole 2,3,-Dioxygenase/antagonists & inhibitors ; Indoleamine-Pyrrole 2,3,-Dioxygenase/blood ; Kynurenine/metabolism ; Male ; Middle Aged ; Receptors, Aryl Hydrocarbon/antagonists & inhibitors ; Receptors, Aryl Hydrocarbon/blood ; Signal Transduction/drug effects ; Tryptophan/pharmacology ; Urinary Bladder Neoplasms/blood ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe