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    Wyświetlanie 1-16 z 16
    Tytuł:
    Neutralizing Antibodies Limit Cell-Associated Spread of Human Cytomegalovirus in Epithelial Cells and Fibroblasts.
    Autorzy:
    Reuter N; Virologisches Institut, Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
    Kropff B; Virologisches Institut, Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
    Britt WJ; Departments of Pediatrics, Microbiology and Neurobiology, School of Medicine, Children's Hospital of Alabama, University of Alabama, Birmingham, AL 35294, USA.
    Mach M; Virologisches Institut, Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
    Thomas M; Virologisches Institut, Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
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    Źródło:
    Viruses [Viruses] 2022 Jan 28; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Neutralizing/*immunology
    Antibodies, Viral/*immunology
    Cytomegalovirus/*immunology
    Cytomegalovirus/*physiology
    Epithelial Cells/*virology
    Fibroblasts/*virology
    Antibodies, Monoclonal/immunology ; Cell Line ; Cells, Cultured ; Humans ; Viral Envelope Proteins/immunology ; Viral Plaque Assay ; Virus Internalization
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cytomegalovirus Infection and Inflammation in Developing Brain.
    Autorzy:
    Krstanović F; Center for Proteomics and Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.
    Britt WJ; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
    Jonjić S; Center for Proteomics and Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.
    Brizić I; Center for Proteomics and Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.
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    Źródło:
    Viruses [Viruses] 2021 Jun 04; Vol. 13 (6). Date of Electronic Publication: 2021 Jun 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Brain/*virology
    Central Nervous System/*virology
    Cytomegalovirus/*pathogenicity
    Cytomegalovirus Infections/*complications
    Inflammation/*virology
    Animals ; Brain/immunology ; Brain/pathology ; Central Nervous System/immunology ; Central Nervous System/pathology ; Cytomegalovirus/immunology ; Cytomegalovirus Infections/immunology ; Cytomegalovirus Infections/pathology ; Disease Models, Animal ; Humans ; Inflammation/pathology ; Mice ; Muromegalovirus ; Viral Tropism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection.
    Autorzy:
    Dobbins GC; Department of Pediatrics, The University of Alabama School of Medicine, CHB 116, 1600 6th Avenue South, Birmingham, AL, USA. .
    Patki A; Department of Biostatistics, The University of Alabama School of Public Health, Birmingham, AL, USA.
    Chen D; Informatics Institute, The University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
    Tiwari HK; Department of Biostatistics, The University of Alabama School of Public Health, Birmingham, AL, USA.
    Hendrickson C; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, AL, USA.
    Britt WJ; Department of Pediatrics, The University of Alabama School of Medicine, CHB 116, 1600 6th Avenue South, Birmingham, AL, USA.; Informatics Institute, The University of Alabama at Birmingham, Birmingham, AL, USA.
    Fowler K; Department of Pediatrics, The University of Alabama School of Medicine, CHB 116, 1600 6th Avenue South, Birmingham, AL, USA.
    Chen JY; Informatics Institute, The University of Alabama at Birmingham, Birmingham, AL, USA.
    Boppana SB; Department of Pediatrics, The University of Alabama School of Medicine, CHB 116, 1600 6th Avenue South, Birmingham, AL, USA.; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, AL, USA.
    Ross SA; Department of Pediatrics, The University of Alabama School of Medicine, CHB 116, 1600 6th Avenue South, Birmingham, AL, USA. .; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, AL, USA. .
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    Źródło:
    BMC infectious diseases [BMC Infect Dis] 2019 Dec 10; Vol. 19 (1), pp. 1046. Date of Electronic Publication: 2019 Dec 10.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cytomegalovirus/*genetics
    Cytomegalovirus Infections/*diagnosis
    DNA, Viral/*genetics
    Hearing Loss, Sensorineural/*diagnosis
    Child ; Cytomegalovirus/classification ; Cytomegalovirus/isolation & purification ; Cytomegalovirus Infections/complications ; Cytomegalovirus Infections/virology ; DNA, Viral/metabolism ; DNA, Viral/urine ; Female ; Hearing Loss, Sensorineural/complications ; High-Throughput Nucleotide Sequencing ; Humans ; Infant ; Infant, Newborn ; Male ; Mutation ; Phylogeny ; Principal Component Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Maternal Immunity and the Natural History of Congenital Human Cytomegalovirus Infection.
    Autorzy:
    Britt WJ; Departments of Pediatrics, Microbiology, and Neurobiology, University of Alabama School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. .
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    Źródło:
    Viruses [Viruses] 2018 Aug 03; Vol. 10 (8). Date of Electronic Publication: 2018 Aug 03.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Review
    MeSH Terms:
    Immunity, Maternally-Acquired*
    Infectious Disease Transmission, Vertical*
    Cytomegalovirus/*physiology
    Cytomegalovirus Infections/*congenital
    Cytomegalovirus Infections/*immunology
    Adaptive Immunity ; Animals ; Clinical Trials as Topic ; Female ; Fetus/immunology ; Fetus/virology ; Humans ; Infant ; Infant, Newborn ; Pregnancy ; Pregnancy Complications, Infectious/immunology ; Pregnancy Complications, Infectious/virology ; Uterus/virology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Human Cytomegalovirus Nuclear Capsids Associate with the Core Nuclear Egress Complex and the Viral Protein Kinase pUL97.
    Autorzy:
    Milbradt J; Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany. .
    Sonntag E; Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany. .
    Wagner S; Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany. .
    Strojan H; Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany. .
    Wangen C; Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany. .
    Lenac Rovis T; Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia. .
    Lisnic B; Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia. .
    Jonjic S; Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia. .
    Sticht H; Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany. .
    Britt WJ; Departments of Pediatrics and Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. .
    Schlötzer-Schrehardt U; Department of Ophthalmology, University Medical Center Erlangen, Erlangen 91054, Germany. .
    Marschall M; Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany. .
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    Źródło:
    Viruses [Viruses] 2018 Jan 13; Vol. 10 (1). Date of Electronic Publication: 2018 Jan 13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Capsid/*physiology
    Cytomegalovirus/*enzymology
    Cytomegalovirus/*physiology
    Nuclear Envelope/*virology
    Phosphotransferases (Alcohol Group Acceptor)/*metabolism
    Protein Kinases/*metabolism
    Cell Nucleus/ultrastructure ; Cell Nucleus/virology ; Cytomegalovirus/ultrastructure ; Host-Pathogen Interactions ; Humans ; Immunohistochemistry ; Microscopy, Electron ; Nuclear Envelope/ultrastructure ; Nuclear Lamina/ultrastructure ; Nuclear Lamina/virology ; Phosphorylation ; Viral Proteins/metabolism ; Virus Assembly ; Virus Release ; Virus Replication
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase.
    Autorzy:
    Liu XJ; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.; University of Chinese Academy of Sciences, Beijing, China.
    Yang B; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
    Huang SN; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
    Wu CC; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
    Li XJ; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
    Cheng S; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
    Jiang X; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.; Guangzhou Institute of Pediatrics, Guangzhou Women and Children Medical Center, Guangzhou, China.
    Hu F; Wuhan Brain Hospital, Ministry of Transportation, Wuhan, Hubei, China.
    Ming YZ; The Third Xiangya Hospital, South Central University, Changsha, Hunan, China.
    Nevels M; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, Fife, United Kingdom.
    Britt WJ; Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama, United States of America.
    Rayner S; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.; Department of Medical Genetics, Oslo University Hospital & University of Oslo, Oslo, Norway.
    Tang Q; Department of Microbiology, Howard University College of Medicine, Howard University, Washington DC, United States of America.
    Zeng WB; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
    Zhao F; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
    Luo MH; State Key Laboratory of Virology, CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.; University of Chinese Academy of Sciences, Beijing, China.; Guangzhou Institute of Pediatrics, Guangzhou Women and Children Medical Center, Guangzhou, China.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2017 Jul 27; Vol. 13 (7), pp. e1006542. Date of Electronic Publication: 2017 Jul 27 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cytomegalovirus/*metabolism
    Cytomegalovirus Infections/*enzymology
    Cytomegalovirus Infections/*virology
    Neural Stem Cells/*metabolism
    Transcription Factor HES-1/*genetics
    Ubiquitin-Protein Ligases/*metabolism
    Cytomegalovirus/genetics ; Cytomegalovirus Infections/genetics ; Down-Regulation ; Host-Pathogen Interactions ; Humans ; Immediate-Early Proteins/genetics ; Immediate-Early Proteins/metabolism ; Neural Stem Cells/enzymology ; Neural Stem Cells/virology ; Protein Binding ; Proteolysis ; Transcription Factor HES-1/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Microbial Cryptotopes are Prominent Targets of B-cell Immunity.
    Autorzy:
    Rieder FJ; Department of Medicine I, Div. of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
    Biebl J; Department of Medicine I, Div. of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
    Kastner MT; Department of Medicine I, Div. of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
    Schneider M; Department of Medicine I, Div. of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
    Jungbauer C; Blood Donation Center of the Austrian Red Cross for Vienna, Lower Austria and Burgenland, Vienna, Austria.
    Redlberger-Fritz M; Department of Virology, Medical University of Vienna, Kinderspitalgasse 15, Vienna, Austria.
    Britt WJ; Department of Pediatrics, Children's Hospital, Birmingham, USA.
    Kundi M; Institute for Environmental Hygiene, Medical University of Vienna, Vienna, Austria.
    Steininger C; Department of Medicine I, Div. of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
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    Źródło:
    Scientific reports [Sci Rep] 2016 Aug 19; Vol. 6, pp. 31657. Date of Electronic Publication: 2016 Aug 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    B-Lymphocytes/*immunology
    Cytomegalovirus/*immunology
    Epitopes, B-Lymphocyte/*immunology
    Escherichia coli/*immunology
    Immunity, Cellular/*immunology
    Staphylococcus aureus/*immunology
    Adult ; Aged ; Antibodies, Bacterial/immunology ; Antibodies, Viral/immunology ; Humans ; Male ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirus.
    Autorzy:
    Dai X; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA.
    Yu X
    Gong H
    Jiang X
    Abenes G
    Liu H
    Shivakoti S
    Britt WJ
    Zhu H
    Liu F
    Zhou ZH
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2013 Aug; Vol. 9 (8), pp. e1003525. Date of Electronic Publication: 2013 Aug 15.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Virus Assembly*
    Capsid/*chemistry
    Capsid Proteins/*metabolism
    Cytomegalovirus/*physiology
    DNA, Viral/*genetics
    Phosphoproteins/*metabolism
    Viral Matrix Proteins/*metabolism
    Virion/*metabolism
    Amino Acid Sequence ; Blotting, Northern ; Blotting, Western ; Capsid/metabolism ; Capsid/ultrastructure ; Capsid Proteins/chemistry ; Cells, Cultured ; Cryoelectron Microscopy ; Cytomegalovirus Infections/genetics ; Cytomegalovirus Infections/metabolism ; Cytomegalovirus Infections/virology ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Fibroblasts/virology ; Humans ; Molecular Sequence Data ; Phosphoproteins/chemistry ; Protein Conformation ; RNA, Catalytic/metabolism ; Viral Matrix Proteins/chemistry ; Virion/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Human cytomegalovirus induces TGF-β1 activation in renal tubular epithelial cells after epithelial-to-mesenchymal transition.
    Autorzy:
    Shimamura M; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America. />Murphy-Ullrich JE
    Britt WJ
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2010 Nov 04; Vol. 6 (11), pp. e1001170. Date of Electronic Publication: 2010 Nov 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cytomegalovirus/*pathogenicity
    Cytomegalovirus Infections/*metabolism
    Kidney Tubules, Proximal/*metabolism
    Kidney Tubules, Proximal/*virology
    Transforming Growth Factor beta1/*metabolism
    Animals ; Blotting, Western ; Cell Differentiation ; Cells, Cultured ; Cytomegalovirus Infections/pathology ; Cytomegalovirus Infections/virology ; Epithelial Cells/metabolism ; Epithelial Cells/virology ; Epithelial-Mesenchymal Transition ; Fluorescent Antibody Technique ; Humans ; Immunoprecipitation ; Kidney Tubules, Proximal/cytology ; RNA, Messenger/genetics ; Rats ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer.
    Autorzy:
    Harkins L; Pathology Service, Birmingham Veterans Affairs Hospital, Birmingham, AL, USA.
    Volk AL
    Samanta M
    Mikolaenko I
    Britt WJ
    Bland KI
    Cobbs CS
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    Źródło:
    Lancet (London, England) [Lancet] 2002 Nov 16; Vol. 360 (9345), pp. 1557-63.
    Typ publikacji:
    Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Viral Proteins*
    Colorectal Neoplasms/*virology
    Cytomegalovirus/*isolation & purification
    Immediate-Early Proteins/*analysis
    Nucleic Acids/*analysis
    Viral Matrix Proteins/*analysis
    Adenocarcinoma/virology ; Caco-2 Cells ; Colonic Polyps/virology ; Cyclooxygenase 2 ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Isoenzymes/analysis ; Membrane Proteins ; Polymerase Chain Reaction ; Prostaglandin-Endoperoxide Synthases/analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-16 z 16

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