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Wyświetlanie 1-12 z 12
Tytuł:
Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein.
Autorzy:
Sagar S; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Rathinavel AK; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Lutz WE; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Struble LR; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, Maryland, USA.
Schnaubelt AT; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Mishra NK; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Guda C; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Palermo NY; Computational Chemistry Core, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Broadhurst MJ; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Hoffmann T; Advanced Light and Electron Microscopy, Centre for Biological Threats and Special Pathogens 4 (ZBS 4), Robert Koch Institute, Berlin, Germany.
Bayles KW; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Reid SPM; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Borgstahl GEO; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Radhakrishnan P; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2021 Feb; Vol. 11 (2), pp. e281.
Typ publikacji:
Letter
MeSH Terms:
COVID-19*/metabolism
COVID-19*/pathology
COVID-19 Drug Treatment*
Angiotensin-Converting Enzyme 2/*metabolism
Bromelains/*pharmacology
SARS-CoV-2/*metabolism
Serine Endopeptidases/*metabolism
Spike Glycoprotein, Coronavirus/*metabolism
Animals ; Chlorocebus aethiops ; Humans ; Vero Cells
Opinia redakcyjna
Tytuł:
Author Correction: Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care.
Autorzy:
Santarpia JL; University of Nebraska Medical Center, Omaha, NE, USA. .; National Strategic Research Institute, Omaha, NE, USA. .
Rivera DN; National Strategic Research Institute, Omaha, NE, USA.
Herrera VL; University of Nebraska Medical Center, Omaha, NE, USA.
Morwitzer MJ; University of Nebraska Medical Center, Omaha, NE, USA.
Creager HM; University of Nebraska Medical Center, Omaha, NE, USA.
Santarpia GW; University of Nebraska Medical Center, Omaha, NE, USA.
Crown KK; National Strategic Research Institute, Omaha, NE, USA.
Brett-Major DM; University of Nebraska Medical Center, Omaha, NE, USA.
Schnaubelt ER; University of Nebraska Medical Center, Omaha, NE, USA.; United States Air Force School of Aerospace Medicine, San Antonio, TX, USA.
Broadhurst MJ; University of Nebraska Medical Center, Omaha, NE, USA.
Lawler JV; University of Nebraska Medical Center, Omaha, NE, USA.; National Strategic Research Institute, Omaha, NE, USA.
Reid SP; University of Nebraska Medical Center, Omaha, NE, USA.
Lowe JJ; University of Nebraska Medical Center, Omaha, NE, USA.; National Strategic Research Institute, Omaha, NE, USA.
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Źródło:
Scientific reports [Sci Rep] 2020 Aug 12; Vol. 10 (1), pp. 13892. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji:
Journal Article; Published Erratum
Czasopismo naukowe
Tytuł:
Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care.
Autorzy:
Santarpia JL; University of Nebraska Medical Center, Omaha, NE, USA. .; National Strategic Research Institute, Omaha, NE, USA. .
Rivera DN; National Strategic Research Institute, Omaha, NE, USA.
Herrera VL; University of Nebraska Medical Center, Omaha, NE, USA.
Morwitzer MJ; University of Nebraska Medical Center, Omaha, NE, USA.
Creager HM; University of Nebraska Medical Center, Omaha, NE, USA.
Santarpia GW; University of Nebraska Medical Center, Omaha, NE, USA.
Crown KK; National Strategic Research Institute, Omaha, NE, USA.
Brett-Major DM; University of Nebraska Medical Center, Omaha, NE, USA.
Schnaubelt ER; University of Nebraska Medical Center, Omaha, NE, USA.; United States Air Force School of Aerospace Medicine, San Antonio, TX, USA.
Broadhurst MJ; University of Nebraska Medical Center, Omaha, NE, USA.
Lawler JV; University of Nebraska Medical Center, Omaha, NE, USA.; National Strategic Research Institute, Omaha, NE, USA.
Reid SP; University of Nebraska Medical Center, Omaha, NE, USA.
Lowe JJ; University of Nebraska Medical Center, Omaha, NE, USA.; National Strategic Research Institute, Omaha, NE, USA.
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Źródło:
Scientific reports [Sci Rep] 2020 Jul 29; Vol. 10 (1), pp. 12732. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aerosols/*analysis
Betacoronavirus/*genetics
Coronavirus Infections/*pathology
Pneumonia, Viral/*pathology
Air Pollutants/analysis ; Betacoronavirus/isolation & purification ; Betacoronavirus/physiology ; COVID-19 ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Humans ; Infection Control/methods ; Pandemics ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Public Health ; RNA, Viral/isolation & purification ; RNA, Viral/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Time Factors
Czasopismo naukowe
Tytuł:
Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study.
Autorzy:
Semper AE; Public Health England, Porton Down, United Kingdom.
Broadhurst MJ; Partners In Health, Boston, Massachusetts, United States of America.
Richards J; Public Health England Laboratory, Port Loko, Sierra Leone.; Mid Essex Hospital Services NHS Trust, Chelmsford, United Kingdom.
Foster GM; Public Health England Laboratory, Port Loko, Sierra Leone.; Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Simpson AJ; Public Health England, Porton Down, United Kingdom.; Public Health England Laboratory, Port Loko, Sierra Leone.
Logue CH; Public Health England, Porton Down, United Kingdom.
Kelly JD; Wellbody Alliance, Freetown, Sierra Leone.
Miller A; Partners In Health, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.
Brooks TJ; Public Health England, Porton Down, United Kingdom.; Public Health England Laboratory, Port Loko, Sierra Leone.
Murray M; Partners In Health, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.
Pollock NR; Partners In Health, Boston, Massachusetts, United States of America.; Department of Laboratory Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
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Źródło:
PLoS medicine [PLoS Med] 2016 Mar 29; Vol. 13 (3), pp. e1001980. Date of Electronic Publication: 2016 Mar 29 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ebolavirus/*genetics
Glycoproteins/*genetics
Hemorrhagic Fever, Ebola/*diagnosis
Nucleoproteins/*genetics
RNA, Viral/*blood
Real-Time Polymerase Chain Reaction/*methods
Reverse Transcriptase Polymerase Chain Reaction/*methods
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Hemorrhagic Fever, Ebola/blood ; Humans ; Infant ; Male ; Middle Aged ; Point-of-Care Systems ; Sensitivity and Specificity ; Sierra Leone ; Young Adult
Czasopismo naukowe
Tytuł:
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.
Autorzy:
Broadhurst MJ; Division of Experimental Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Leung JM
Lim KC
Girgis NM
Gundra UM
Fallon PG
Premenko-Lanier M
McKerrow JH
McCune JM
Loke P
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Źródło:
PLoS pathogens [PLoS Pathog] 2012; Vol. 8 (8), pp. e1002883. Date of Electronic Publication: 2012 Aug 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Enzymologic/*immunology
Macrophage Activation/*immunology
Macrophages, Peritoneal/*immunology
Retinal Dehydrogenase/*immunology
Schistosoma mansoni/*immunology
Schistosomiasis mansoni/*immunology
Up-Regulation/*immunology
Animals ; Cells, Cultured ; Forkhead Transcription Factors/biosynthesis ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/immunology ; Gene Expression Regulation, Enzymologic/genetics ; Macrophage Activation/genetics ; Mice ; Mice, Knockout ; Retinal Dehydrogenase/biosynthesis ; Retinal Dehydrogenase/genetics ; Schistosoma mansoni/metabolism ; Schistosomiasis mansoni/enzymology ; Schistosomiasis mansoni/genetics ; Th1 Cells/immunology ; Th2 Cells/immunology ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł:
Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.
Autorzy:
Broadhurst MJ; Division of Experimental Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America. mara.broadhurst@ucsf.edu
Ardeshir A
Kanwar B
Mirpuri J
Gundra UM
Leung JM
Wiens KE
Vujkovic-Cvijin I
Kim CC
Yarovinsky F
Lerche NW
McCune JM
Loke P
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Źródło:
PLoS pathogens [PLoS Pathog] 2012; Vol. 8 (11), pp. e1003000. Date of Electronic Publication: 2012 Nov 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Therapy with Helminths*
Trichuris*
Colon/*immunology
Diarrhea/*immunology
Diarrhea/*therapy
Diarrhea/*veterinary
Intestinal Mucosa/*immunology
Monkey Diseases/*immunology
Monkey Diseases/*therapy
Animals ; Chronic Disease ; Colon/microbiology ; Cyanobacteria/immunology ; Diarrhea/microbiology ; Female ; Inflammation/immunology ; Inflammation/microbiology ; Inflammation/therapy ; Intestinal Mucosa/microbiology ; Macaca mulatta ; Male ; Monkey Diseases/microbiology ; Th1 Cells/immunology ; Th2 Cells/immunology
Czasopismo naukowe
    Wyświetlanie 1-12 z 12

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