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Tytuł :
Insulin acutely increases agonist-induced airway smooth muscle contraction in humans and rats.
Autorzy :
Proskocil BJ; Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon.
Calco GN; Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon.
Nie Z; Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Apr 01; Vol. 320 (4), pp. L545-L556. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bronchoconstriction*
Muscle Contraction*
Bronchial Hyperreactivity/*pathology
Hyperinsulinism/*complications
Insulin/*adverse effects
Methacholine Chloride/*pharmacology
Muscle, Smooth/*pathology
Animals ; Bronchial Hyperreactivity/etiology ; Bronchial Hyperreactivity/metabolism ; Calcium/metabolism ; Humans ; Hypoglycemic Agents/adverse effects ; Male ; Muscarinic Agonists/pharmacology ; Muscle, Smooth/drug effects ; Muscle, Smooth/metabolism ; Obesity/complications ; Rats ; Rats, Sprague-Dawley ; Receptors, Muscarinic/metabolism ; Trachea/drug effects ; Trachea/pathology ; Vagus Nerve/physiopathology
Czasopismo naukowe
Tytuł :
Callicarpa japonica Thunb. ameliorates allergic airway inflammation by suppressing NF-κB activation and upregulating HO-1 expression.
Autorzy :
Kim SM; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea; College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, Republic of Korea. Electronic address: .
Ryu HW; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea. Electronic address: .
Kwon OK; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea. Electronic address: .
Hwang D; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea; College of Pharmacy, Chungbuk National University, Cheongju-si, Chungcheongbuk-do, 28160, Republic of Korea. Electronic address: .
Kim MG; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea; College of Pharmacy, Chungbuk National University, Cheongju-si, Chungcheongbuk-do, 28160, Republic of Korea. Electronic address: .
Min JH; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea; College of Pharmacy, Chungbuk National University, Cheongju-si, Chungcheongbuk-do, 28160, Republic of Korea. Electronic address: .
Zhang Z; State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, the Chinese Academy of Sciences, Beijing, 100093, PR China. Electronic address: .
Kim SY; International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea. Electronic address: .
Paik JH; International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea. Electronic address: .
Oh SR; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea. Electronic address: .
Ahn KS; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea. Electronic address: .
Lee JW; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Chungbuk, 28116, Republic of Korea. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113523. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Callicarpa*/chemistry
Anti-Asthmatic Agents/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Asthma/*prevention & control
Bronchial Hyperreactivity/*prevention & control
Heme Oxygenase-1/*metabolism
Lung/*drug effects
Membrane Proteins/*metabolism
NF-kappa B/*metabolism
Plant Extracts/*pharmacology
A549 Cells ; Animals ; Anti-Asthmatic Agents/isolation & purification ; Anti-Inflammatory Agents/isolation & purification ; Asthma/chemically induced ; Asthma/enzymology ; Asthma/physiopathology ; Bronchial Hyperreactivity/chemically induced ; Bronchial Hyperreactivity/enzymology ; Bronchial Hyperreactivity/physiopathology ; Bronchoconstriction/drug effects ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Humans ; Lung/enzymology ; Lung/physiopathology ; Mice ; Mice, Inbred BALB C ; Ovalbumin ; Plant Extracts/isolation & purification ; RAW 264.7 Cells ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Cellular clocks in hyperoxia effects on [Ca ] i regulation in developing human airway smooth muscle.
Autorzy :
Bartman CM; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Matveyenko A; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Pabelick C; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Prakash YS; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Mar 01; Vol. 320 (3), pp. L451-L466. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Circadian Clocks*
Bronchi/*metabolism
Bronchial Hyperreactivity/*metabolism
Calcium/*metabolism
Hyperoxia/*physiopathology
Muscle, Smooth/*metabolism
Oxygen/*metabolism
Animals ; Bronchi/pathology ; Bronchial Hyperreactivity/pathology ; Cell Proliferation ; Cells, Cultured ; Female ; Fetus/metabolism ; Fetus/pathology ; Humans ; Infant, Newborn ; Male ; Mice, Inbred C57BL ; Muscle, Smooth/pathology
Czasopismo naukowe
Tytuł :
DM-induced Hypermethylation of IR and IGF1R attenuates mast cell activation and airway responsiveness in rats.
Autorzy :
Fu D; Department of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, China.
Zhao H; Diabetic Systems Center, Guangxi Key Laboratory of Excellence, Guilin Medical University, Guilin, China.
He L; Department of Anesthesiology, Affiliated Hospital of Guilin Medical University, Guilin, China.
Feng H; Department of Anesthesiology, Affiliated Hospital of Guilin Medical University, Guilin, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Dec; Vol. 24 (24), pp. 14381-14391. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bronchial Hyperreactivity/*etiology
Bronchial Hyperreactivity/*metabolism
Mast Cells/*immunology
Mast Cells/*metabolism
Receptor, IGF Type 1/*metabolism
Receptor, Insulin/*metabolism
Allergens/immunology ; Animals ; Asthma/etiology ; Asthma/metabolism ; Asthma/physiopathology ; Biomarkers ; Bronchial Hyperreactivity/physiopathology ; Cytokines/metabolism ; Diabetes Mellitus, Experimental ; Disease Models, Animal ; Disease Susceptibility ; Gene Expression ; Gene Knockdown Techniques ; Histamine/biosynthesis ; Immunoglobulin E/immunology ; Inflammation Mediators/metabolism ; Insulin/metabolism ; Methylation ; Rats ; Receptor, IGF Type 1/genetics ; Receptor, Insulin/genetics
Czasopismo naukowe
Tytuł :
Role of CD4 T Cells in Allergic Airway Diseases: Learning from Murine Models.
Autorzy :
Miura K; Department of Disease Model, Research Institute of Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.; RIKEN BioResource Research Center, Ibaraki 305-0074, Japan.
Inoue K; RIKEN BioResource Research Center, Ibaraki 305-0074, Japan.
Ogura A; RIKEN BioResource Research Center, Ibaraki 305-0074, Japan.
Kaminuma O; Department of Disease Model, Research Institute of Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan.; RIKEN BioResource Research Center, Ibaraki 305-0074, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 11; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Susceptibility*/immunology
Bronchial Hyperreactivity/*etiology
Bronchial Hyperreactivity/*metabolism
CD4-Positive T-Lymphocytes/*immunology
CD4-Positive T-Lymphocytes/*metabolism
Animals ; Biomarkers ; Bronchial Hyperreactivity/diagnosis ; Cell Communication ; Disease Models, Animal ; Humans ; Immunoglobulin E/immunology ; Inflammation/etiology ; Inflammation/metabolism ; Inflammation/pathology ; Mast Cells/immunology ; Mast Cells/metabolism ; Mice ; Mice, Transgenic ; Receptors, Antigen, T-Cell/metabolism ; Signal Transduction ; T-Cell Antigen Receptor Specificity ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism
Czasopismo naukowe
Tytuł :
Cysteamine prevents asthma development and reduces airway hyperresponsiveness in experimental asthma.
Autorzy :
Bolcas PE; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Immunology Graduate Program, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Brandt EB; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Ruff BP; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Kalra M; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
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Źródło :
Allergy [Allergy] 2020 Oct; Vol. 75 (10), pp. 2675-2677. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Letter
MeSH Terms :
Asthma*/drug therapy
Asthma*/etiology
Asthma*/prevention & control
Bronchial Hyperreactivity*/etiology
Bronchial Hyperreactivity*/prevention & control
Respiration Disorders*
Respiratory Hypersensitivity*
Cysteamine/therapeutic use ; Humans
Opinia redakcyjna
Tytuł :
Induction of ferroptosis-like cell death of eosinophils exerts synergistic effects with glucocorticoids in allergic airway inflammation.
Autorzy :
Wu Y; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Chen H; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Xuan N; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Zhou L; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Wu Y; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Zhu C; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Li M; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Weng Q; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Shen J; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Zhang H; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Zhang B; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Lan F; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Xia L; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Xiong X; Department of Respiratory Medicine, Central Hospital of Lishui City, Lishui, Zhejiang, China.
Li Z; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Zhao Y; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Wu M; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Ying S; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China.
Li W; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China .
Shen H; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China .; State Key Lab for Respiratory Diseases, National Clinical Research Centre for Respiratory Disease, Guangzhou, Guangdong, China.
Chen Z; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang, China .
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Źródło :
Thorax [Thorax] 2020 Nov; Vol. 75 (11), pp. 918-927. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ferroptosis*
Bronchial Hyperreactivity/*drug therapy
Eosinophils/*cytology
Animals ; Artesunate/pharmacology ; Benzylamines/pharmacology ; Bronchial Hyperreactivity/pathology ; Bronchoalveolar Lavage Fluid/cytology ; Dexamethasone/pharmacology ; Drug Synergism ; Eosinophils/pathology ; Glucocorticoids/pharmacology ; Humans ; Imidazoles/pharmacology ; Indoles/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Piperazines/pharmacology ; Quinazolines/pharmacology
Czasopismo naukowe
Tytuł :
Reply to: The Intricate Web of Phospholipase A 2 s and Specific Features of Airway Hyperresponsiveness in Asthma.
Autorzy :
Ueno H; Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Koya T; Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2020 Oct; Vol. 63 (4), pp. 545-546.
Typ publikacji :
Letter; Comment
MeSH Terms :
Asthma*
Bronchial Hyperreactivity*
Airway Remodeling ; Bronchoconstriction ; Humans ; Leukotrienes ; Phospholipases ; Phospholipases A2
Opinia redakcyjna
Tytuł :
Cobalt exposure via skin alters lung immune cells and enhances pulmonary responses to cobalt in mice.
Autorzy :
Tsui HC; Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Decaesteker T; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Jonckheere AC; Allergy and Clinical Immunology Research Group, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
Vande Velde G; Biomedical MRI, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Cremer J; Translational Research in Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Verbeken E; Translational Cell and Tissue Research, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Hoet PHM; Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Nemery B; Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Vanoirbeek JAJ; Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 Oct 01; Vol. 319 (4), pp. L641-L651. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bronchial Hyperreactivity/*drug therapy
Cobalt/*pharmacology
Inflammation/*drug therapy
Lymphocytes/*drug effects
Animals ; Bronchial Hyperreactivity/immunology ; Bronchoalveolar Lavage/methods ; Bronchoalveolar Lavage Fluid/immunology ; Disease Models, Animal ; Inflammation/chemically induced ; Lung/drug effects ; Lung/immunology ; Lymphocytes/immunology ; Methacholine Chloride/metabolism ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł :
The Intricate Web of Phospholipase A 2 s and Specific Features of Airway Hyperresponsiveness in Asthma.
Autorzy :
Murphy RC; University of Washington, Seattle, Washington.
Altemeier WA; University of Washington, Seattle, Washington.
Lai Y; University of Washington, Seattle, Washington.
Hallstrand TS; University of Washington, Seattle, Washington.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2020 Oct; Vol. 63 (4), pp. 543-545.
Typ publikacji :
Letter; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Asthma*
Bronchial Hyperreactivity*
Airway Remodeling ; Bronchoconstriction ; Humans ; Leukotrienes ; Phospholipases ; Phospholipases A2
Raport
Tytuł :
Qingfei oral liquid alleviates airway hyperresponsiveness and mucus hypersecretion via TRPV1 signaling in RSV-infected asthmatic mice.
Autorzy :
Jing X; Department of Traditional Chinese Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200040, China. Electronic address: .
Yan W; Department of Traditional Chinese Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200040, China.
Zeng H; Department of Traditional Chinese Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200040, China.
Cheng W; Department of Traditional Chinese Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200040, China.
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Aug; Vol. 128, pp. 110340. Date of Electronic Publication: 2020 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma/*drug therapy
Bronchial Hyperreactivity/*drug therapy
Bronchoconstriction/*drug effects
Drugs, Chinese Herbal/*administration & dosage
Lung/*drug effects
Mucin 5AC/*metabolism
Respiratory Syncytial Virus Infections/*drug therapy
TRPV Cation Channels/*antagonists & inhibitors
Administration, Oral ; Animals ; Asthma/metabolism ; Asthma/physiopathology ; Asthma/virology ; Bronchial Hyperreactivity/metabolism ; Bronchial Hyperreactivity/physiopathology ; Bronchial Hyperreactivity/virology ; Cytokines/metabolism ; Disease Models, Animal ; Inflammation Mediators/metabolism ; Lung/metabolism ; Lung/physiopathology ; Lung/virology ; Male ; Mice, Inbred BALB C ; NF-kappa B/metabolism ; Protein Kinase C/metabolism ; Respiratory Syncytial Virus Infections/metabolism ; Respiratory Syncytial Virus Infections/physiopathology ; Respiratory Syncytial Virus Infections/virology ; Secretory Pathway ; Signal Transduction ; TRPV Cation Channels/metabolism
Czasopismo naukowe
Tytuł :
Early bronchial inflammation and remodeling and airway hyperresponsiveness at school age.
Autorzy :
Malmberg LP; Department of Allergy, Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Malmström K; Department of Allergy, Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Kotaniemi-Syrjänen A; Department of Allergy, Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Lohi J; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Pelkonen AS; Department of Allergy, Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Sarna S; Department of Public Health, University of Helsinki Finland, Helsinki, Finland.
Mäkelä MJ; Department of Allergy, Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
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Źródło :
Allergy [Allergy] 2020 Jul; Vol. 75 (7), pp. 1765-1768. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Bronchial Hyperreactivity*/diagnosis
Bronchial Hyperreactivity*/etiology
Respiratory Hypersensitivity*
Airway Remodeling ; Bronchi ; Humans ; Inflammation ; Schools
Raport
Tytuł :
Protein S protects against allergic bronchial asthma by modulating Th1/Th2 balance.
Autorzy :
Asayama K; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Kobayashi T; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
D'Alessandro-Gabazza CN; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.
Toda M; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.
Yasuma T; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.; Department of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Tsu, Japan.
Fujimoto H; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Okano T; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Saiki H; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Takeshita A; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.; Department of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Tsu, Japan.
Fujiwara K; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Fridman D'Alessandro V; Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu, Japan.; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.
Nishihama K; Department of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Tsu, Japan.
Totoki T; Department of Gastroenterology, Mie University Graduate School of Medicine, Tsu, Japan.
Inoue R; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.; Central Institute for Experimental Animals, Kawasaki-ku, Japan.
Takei Y; Department of Gastroenterology, Mie University Graduate School of Medicine, Tsu, Japan.
Gabazza EC; Department of Immunology, Mie University Graduate School of Medicine, Tsu, Japan.
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Źródło :
Allergy [Allergy] 2020 Sep; Vol. 75 (9), pp. 2267-2278. Date of Electronic Publication: 2020 Mar 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Asthma*/prevention & control
Bronchial Hyperreactivity*
Animals ; Cytokines ; Disease Models, Animal ; Humans ; Immunoglobulin E ; Lung ; Mice ; Mice, Inbred BALB C ; Ovalbumin ; Protein S ; Th2 Cells
Czasopismo naukowe
Tytuł :
Calcilytics: a non-steroidal replacement for inhaled steroid and SABA/LABA therapy of human asthma?
Autorzy :
Corrigan CJ; Faculty of Life Sciences and Medicine, School of Immunology & Microbial Sciences, Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London , London, UK.
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Źródło :
Expert review of respiratory medicine [Expert Rev Respir Med] 2020 Aug; Vol. 14 (8), pp. 807-816. Date of Electronic Publication: 2020 May 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Airway Obstruction/*drug therapy
Anti-Asthmatic Agents/*pharmacology
Asthma/*drug therapy
Bronchial Hyperreactivity/*drug therapy
Receptors, Calcium-Sensing/*antagonists & inhibitors
Administration, Inhalation ; Adrenal Cortex Hormones ; Airway Obstruction/complications ; Airway Obstruction/etiology ; Anti-Asthmatic Agents/administration & dosage ; Anti-Asthmatic Agents/therapeutic use ; Asthma/complications ; Bronchial Hyperreactivity/complications ; Bronchodilator Agents ; Humans ; Inflammation/drug therapy
Czasopismo naukowe
Tytuł :
Myxopyrum serratulum ameliorates airway inflammation in LPS-stimulated RAW 264.7 macrophages and OVA-induced murine model of allergic asthma.
Autorzy :
Maruthamuthu V; Department of Pharmaceutical Technology, Centre for Excellence in Nanobio Translational Research, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India.
Henry LJK; Department of Pharmaceutical Technology, Centre for Excellence in Nanobio Translational Research, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India; National Facility for Drug Development (NFDD) for Academia, Pharmaceutical and Allied Industries, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India.
Ramar MK; Department of Pharmaceutical Technology, Centre for Excellence in Nanobio Translational Research, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India; National Facility for Drug Development (NFDD) for Academia, Pharmaceutical and Allied Industries, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India.
Kandasamy R; Department of Pharmaceutical Technology, Centre for Excellence in Nanobio Translational Research, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India; National Facility for Drug Development (NFDD) for Academia, Pharmaceutical and Allied Industries, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Jun 12; Vol. 255, pp. 112369. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji :
Journal Article
MeSH Terms :
Oleaceae*/chemistry
Anti-Asthmatic Agents/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Asthma/*prevention & control
Bronchial Hyperreactivity/*prevention & control
Bronchoconstriction/*drug effects
Lung/*drug effects
Macrophages/*drug effects
Plant Extracts/*pharmacology
Animals ; Anti-Asthmatic Agents/isolation & purification ; Anti-Inflammatory Agents/isolation & purification ; Asthma/immunology ; Asthma/metabolism ; Asthma/physiopathology ; Bronchial Hyperreactivity/immunology ; Bronchial Hyperreactivity/metabolism ; Bronchial Hyperreactivity/physiopathology ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Inflammation Mediators/metabolism ; Lipopolysaccharides/pharmacology ; Lung/immunology ; Lung/metabolism ; Lung/physiopathology ; Macrophages/metabolism ; Mice ; Mice, Inbred BALB C ; Nitric Oxide/metabolism ; Ovalbumin ; Plant Extracts/isolation & purification ; Plant Leaves ; RAW 264.7 Cells ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
[Extracellular molecules controlling the contraction of airway smooth muscle and their potential contribution to bronchial hyperresponsiveness].
Autorzy :
Gazzola M; Université Laval, Québec, Canada.
Flamand N; Université Laval, Québec, Canada.
Bossé Y; Université Laval, Québec, Canada. Electronic address: .
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Transliterated Title :
La contractilité du muscle lisse des voies respiratoires est régulée par de nombreuses molécules extracellulaires qui pourraient contribuer à l’hyperréactivité bronchique.
Źródło :
Revue des maladies respiratoires [Rev Mal Respir] 2020 Jun; Vol. 37 (6), pp. 462-473. Date of Electronic Publication: 2020 May 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Bronchial Hyperreactivity/*etiology
Bronchoconstrictor Agents/*pharmacology
Bronchodilator Agents/*pharmacology
Muscle Contraction/*drug effects
Muscle Contraction/*physiology
Animals ; Asthma/etiology ; Asthma/metabolism ; Asthma/physiopathology ; Bronchial Hyperreactivity/metabolism ; Bronchial Hyperreactivity/physiopathology ; Bronchoconstriction/drug effects ; Bronchoconstriction/physiology ; Bronchoconstrictor Agents/metabolism ; Bronchodilator Agents/metabolism ; Extracellular Space/metabolism ; Humans ; Muscle, Smooth/drug effects ; Muscle, Smooth/physiology ; Respiratory System/drug effects ; Respiratory System/metabolism ; Respiratory System/physiopathology
Czasopismo naukowe
Tytuł :
Asthma without borders.
Autorzy :
Prakash YS; Department of Anesthesiology and Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 May 01; Vol. 318 (5), pp. L1001-L1003. Date of Electronic Publication: 2020 Apr 01.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural
MeSH Terms :
Anti-Asthmatic Agents/*therapeutic use
Asthma/*epidemiology
Bronchial Hyperreactivity/*epidemiology
Global Health/*trends
Molecular Targeted Therapy/*methods
Precision Medicine/*methods
Adrenal Cortex Hormones/therapeutic use ; Adrenergic beta-Agonists/therapeutic use ; Age Factors ; Airway Remodeling/drug effects ; Airway Remodeling/immunology ; Animals ; Asthma/drug therapy ; Asthma/etiology ; Asthma/immunology ; Bronchial Hyperreactivity/drug therapy ; Bronchial Hyperreactivity/etiology ; Bronchial Hyperreactivity/immunology ; Environmental Exposure/adverse effects ; Humans ; Sex Factors ; Survival Analysis
Raport
Tytuł :
Soluble pattern recognition molecules: Guardians and regulators of homeostasis at airway mucosal surfaces.
Autorzy :
Smole U; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Kratzer B; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Pickl WF; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
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Źródło :
European journal of immunology [Eur J Immunol] 2020 May; Vol. 50 (5), pp. 624-642.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Asthma/*immunology
Bronchial Hyperreactivity/*immunology
C-Reactive Protein/*immunology
Homeostasis/*immunology
Receptors, Pattern Recognition/*immunology
Respiratory Mucosa/*immunology
Allergens/administration & dosage ; Animals ; Asthma/genetics ; Asthma/pathology ; Bronchial Hyperreactivity/genetics ; Bronchial Hyperreactivity/pathology ; C-Reactive Protein/genetics ; Collectins/genetics ; Collectins/immunology ; Complement C3/genetics ; Complement C3/immunology ; Complement C5/genetics ; Complement C5/immunology ; Epithelial Cells/immunology ; Epithelial Cells/pathology ; Gene Expression Regulation ; Homeostasis/genetics ; Humans ; Lectins/genetics ; Lectins/immunology ; Receptors, Pattern Recognition/genetics ; Respiratory Mucosa/pathology ; Serum Amyloid A Protein/genetics ; Serum Amyloid A Protein/immunology ; Serum Amyloid P-Component/genetics ; Serum Amyloid P-Component/immunology
Czasopismo naukowe
Tytuł :
Progress in Occupational Asthma.
Autorzy :
Tiotiu AI; Department of Pulmonology, University Hospital of Nancy, 54000 Nancy, France.; Development, Adaptation and Disadvantage, Cardiorespiratory Regulations and Motor Control (EA 3450 DevAH), University of Lorraine, 54000 Nancy, France.
Novakova S; Allergy Unit, Internal Consulting Department, University Hospital 'St. George', 4000 Plovdiv, Bulgaria.
Labor M; Department of Pulmonology, University Hospital Centre Osijek, 31000 Osijek, Croatia.; Medical Faculty Osijek, J.J. Strossmayer University, 31000 Osijek, Croatia.
Emelyanov A; Department of Respiratory Medicine, North-Western Medical University, 191015 Saint-Petersburg, Russia.
Mihaicuta S; Victor Babes University of Medicine and Pharmacy, 300120 Timisoara, Romania.
Novakova P; Clinic of Clinical Allergy, Medical University, 1000 Sofia, Bulgaria.
Nedeva D; Medical University Sofia, 1000 Sofia, Bulgaria.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Jun 24; Vol. 17 (12). Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Asthma, Occupational*/diagnosis
Asthma, Occupational*/epidemiology
Asthma, Occupational*/etiology
Bronchial Hyperreactivity*
Hypersensitivity*
Occupational Diseases*
Occupational Exposure*/adverse effects
Humans ; Skin Tests
Czasopismo naukowe
Tytuł :
[The cough variant asthma].
Autorzy :
Uryasjev MO; Ryazan State Medical University.
Ponomareva IV; Ryazan State Medical University.
Bhar M; Ryazan State Medical University.
Glotov SI; Ryazan State Medical University.
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Źródło :
Terapevticheskii arkhiv [Ter Arkh] 2020 Apr 27; Vol. 92 (3), pp. 98-101. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma*
Bronchial Hyperreactivity*
Bronchodilator Agents/therapeutic use ; Cough/drug therapy ; Humans ; Respiratory Sounds
Czasopismo naukowe

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