- Tytuł:
- The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin.
- Autorzy:
- Źródło:
- Scientific reports [Sci Rep] 2016 May 05; Vol. 6, pp. 25505. Date of Electronic Publication: 2016 May 05.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Gene Expression Regulation, Neoplastic*
Breast Neoplasms /*genetics
Calcium/*metabolism
Carcinoma, Basal Cell/*genetics
Cell Transformation, Neoplastic/*genetics
Plasma Membrane Calcium-Transporting ATPases/*genetics
Antibiotics, Antineoplastic/pharmacology ;Breast Neoplasms /drug therapy ;Breast Neoplasms /mortality ;Breast Neoplasms /pathology ; Calcium Signaling ; Carcinoma, Basal Cell/drug therapy ; Carcinoma, Basal Cell/mortality ; Carcinoma, Basal Cell/pathology ; Cell Line, Tumor ; Cell Membrane/drug effects ; Cell Membrane/enzymology ; Cell Membrane/pathology ; Cell Proliferation ; Cell Transformation, Neoplastic/drug effects ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; Doxorubicin/pharmacology ; Epithelial Cells/enzymology ; Epithelial Cells/pathology ; Female ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Lactation/physiology ; Mammary Glands, Human/enzymology ; Mammary Glands, Human/pathology ; Plasma Membrane Calcium-Transporting ATPases/antagonists & inhibitors ; Plasma Membrane Calcium-Transporting ATPases/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Survival Analysis
Czasopismo naukowe