Autor: "Bruce, D" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Impact of HLA class I functional divergence on HIV control.
Autorzy:: Viard M; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute Bethesda, MD, USA.
O'hUigin C; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute Bethesda, MD, USA.
Yuki Y; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute Bethesda, MD, USA.
Bashirova AA; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute Bethesda, MD, USA.
Collins DR; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Urbach JM; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Wolinsky S; Division of Infectious Diseases, Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Buchbinder S; Bridge HIV, San Francisco Department of Public Health, San Francisco, CA, USA.; Department of Medicine, Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Kirk GD; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Goedert JJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Michael NL; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Haas DW; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Deeks SG; Department of Medicine, University of California, San Francisco, CA, USA.
Walker BD; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Yu X; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute Bethesda, MD, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2024 Jan 19; Vol. 383 (6680), pp. 319-325. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:: Journal Article
MeSH Terms:: Heterozygote*
HIV Infections*/genetics
HIV Infections*/pathology
HLA-B Antigens*/genetics
Humans ; Alleles ; Disease Progression ; Peptides/genetics ; Peptides/immunology ; Male ; Female ; Young Adult ; Adult ; Middle Aged ; Aged

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Skocz do pozycji: 2.

Tytuł:: Centering PrEP: utilizing ADAPT-ITT to inform group PrEP care for sex workers in Chicago.
Autorzy:: Singer RB; College of Nursing, University of Illinois Chicago (UIC), Chicago, IL, USA. .
Barrow J; College of Nursing, University of Illinois Chicago (UIC), Chicago, IL, USA.
Johnson AK; Lurie Children's Hospital, Chicago, IL, USA.
Zemlak J; College of Nursing, Marquette University, Milwaukee, WI, USA.
Crooks N; College of Nursing, University of Illinois Chicago (UIC), Chicago, IL, USA.
Abboud S; College of Nursing, University of Illinois Chicago (UIC), Chicago, IL, USA.
Bruce D; College of Science and Health, DePaul University, Chicago, IL, USA.
Green N; Chicago Center for HIV Elimination, Chicago, IL, USA.
Stamps J; Southside Health Advocacy Resource Partnership, Chicago, IL, USA.
Neely J; Northwestern Memorial Hospital, Chicago, IL, USA.
Sherman SG; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Patil CL; College of Nursing, University of Illinois Chicago (UIC), Chicago, IL, USA.; School of Nursing, University of Michigan, Ann Arbor, USA.
Matthews AK; School of Nursing, Columbia University, New York, NY, USA.; Pokaż więcej
Źródło:: BMC public health [BMC Public Health] 2024 Jan 02; Vol. 24 (1), pp. 56. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Sex Workers*
HIV Infections*/prevention & control
HIV Infections*/drug therapy
Pre-Exposure Prophylaxis*
Anti-HIV Agents*/therapeutic use
Humans ; Female ; Pregnancy ; Chicago ; Delivery of Health Care

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Skocz do pozycji: 3.

Tytuł:: Integrating hypertension and HIV care in Namibia: A quality improvement collaborative approach.
Autorzy:: Basenero A; Ministry of Health and Social Services, Windhoek, Namibia.
Neidel J; Institute for Global Health Sciences, University of California, San Francisco, California, United States of America.
Ikeda DJ; Harvard Medical School, Boston, Massachusetts, United States of America.
Ashivudhi H; U.S. Centers for Disease Control and Prevention, Windhoek, Namibia.
Mpariwa S; Ministry of Health and Social Services, Windhoek, Namibia.
Kamangu JWN; Ministry of Health and Social Services, Windhoek, Namibia.
Mpalang Kakubu MA; Ministry of Health and Social Services, Windhoek, Namibia.
Hans L; U.S. Centers for Disease Control and Prevention, Windhoek, Namibia.
Mutandi G; U.S. Centers for Disease Control and Prevention, Windhoek, Namibia.
Jed S; Office of the U.S. Global AIDS Coordinator and Health Diplomacy, Pretoria, South Africa.
Tjituka F; Ministry of Health and Social Services, Windhoek, Namibia.
Hamunime N; Ministry of Health and Social Services, Windhoek, Namibia.
Agins BD; Institute for Global Health Sciences, University of California, San Francisco, California, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Aug 11; Vol. 17 (8), pp. e0272727. Date of Electronic Publication: 2022 Aug 11 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: HIV Infections*/complications
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Hypertension*/drug therapy
Hypertension*/therapy
Adult ; Antihypertensive Agents/therapeutic use ; Humans ; Namibia/epidemiology ; Quality Improvement

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Skocz do pozycji: 4.

Tytuł:: An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults.
Autorzy:: Vieira VA; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Adland E; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Malone DFG; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Martin MP; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America.
Groll A; Department of Statistics, TU Dortmund University, Dortmund, Germany.
Ansari MA; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Garcia-Guerrero MC; IrsiCaixa AIDS Research Institute, Badalona, Spain.
Puertas MC; IrsiCaixa AIDS Research Institute, Badalona, Spain.; CIBER en Enfermedades Infecciosas, Madrid, Spain.
Muenchhoff M; Max von Pettenkofer Institute & Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.
Guash CF; Infectious Diseases and Systemic Inflammatory Response in Pediatrics, Infectious Diseases Unit, Department of Pediatrics, Sant Joan de Déu Hospital Research Foundation, Barcelona, Spain.; Center for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Department of Pediatrics, University of Barcelona, Barcelona, Spain.; Translational Research Network in Pediatric Infectious Diseases (RITIP), Madrid, Spain.
Brander C; IrsiCaixa AIDS Research Institute, Badalona, Spain.; CIBER en Enfermedades Infecciosas, Madrid, Spain.; University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
Martinez-Picado J; IrsiCaixa AIDS Research Institute, Badalona, Spain.; CIBER en Enfermedades Infecciosas, Madrid, Spain.; University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.; Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.
Bamford A; Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.; UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Tudor-Williams G; Department of Infectious Diseases, Imperial College, London, United Kingdom.
Ndung'u T; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.; Africa Health Research Institute (AHRI), Durban, South Africa.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.; Max Planck Institute for Infection Biology, Chariteplatz, Berlin, Germany.; Division of Infection and Immunity, University College London, London, United Kingdom.
Walker BD; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.; Africa Health Research Institute (AHRI), Durban, South Africa.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Ramsuran V; School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
Frater J; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Biomedical Research Centre, Oxford, United Kingdom.
Jooste P; Department of Paediatrics, Kimberley Hospital, Kimberley, South Africa.
Peppa D; Division of Infection and Immunity, University College London, London, United Kingdom.
Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Goulder PJR; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2021 Nov 18; Vol. 17 (11), pp. e1010090. Date of Electronic Publication: 2021 Nov 18 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
HIV Infections/*immunology
HIV-1/*immunology
HLA-B Antigens/*immunology
Histocompatibility Antigens Class I/*immunology
Killer Cells, Natural/*immunology
Receptors, KIR3DL1/*metabolism
Adolescent ; Child ; Child, Preschool ; Cohort Studies ; HIV Infections/metabolism ; HIV Infections/virology ; Humans ; Lymphocyte Activation

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Skocz do pozycji: 5.

Tytuł:: Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection.
Autorzy:: Muema DM; Africa Health Research Institute, Durban, South Africa.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Akilimali NA; Africa Health Research Institute, Durban, South Africa.
Ndumnego OC; Africa Health Research Institute, Durban, South Africa.
Rasehlo SS; Africa Health Research Institute, Durban, South Africa.
Durgiah R; Africa Health Research Institute, Durban, South Africa.
Ojwach DBA; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Ismail N; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Dong M; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Moodley A; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Dong KL; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.; Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA, USA.
Ndhlovu ZM; Africa Health Research Institute, Durban, South Africa.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.; Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA, USA.
Mabuka JM; Africa Health Research Institute, Durban, South Africa.
Walker BD; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.; Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA, USA.
Mann JK; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Ndung'u T; Africa Health Research Institute, Durban, South Africa. .; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa. .; Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA, USA. .; Max Planck Institute for Infection Biology, Berlin, Germany. .; Division of Infection and Immunity, University College London, London, UK. .; Pokaż więcej
Źródło:: BMC medicine [BMC Med] 2020 Mar 25; Vol. 18 (1), pp. 81. Date of Electronic Publication: 2020 Mar 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytokines/*therapeutic use
HIV Infections/*immunology
Viral Load/*methods
Viremia/*immunology
Adolescent ; Adult ; Cytokines/pharmacology ; Female ; HIV Infections/drug therapy ; Humans ; Male ; Young Adult

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Skocz do pozycji: 6.

Tytuł:: High-resolution definition of humoral immune response correlates of effective immunity against HIV.
Autorzy:: Alter G; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Dowell KG; Department of Computer Science, Dartmouth College, Hanover, NH, USA.
Brown EP; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Suscovich TJ; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Mikhailova A; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Mahan AE; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Nimmerjahn F; Department of Biology, Institute of Genetics, University of Erlangen-Nuremberg, Erlangen, Germany.
Bailey-Kellogg C; Department of Computer Science, Dartmouth College, Hanover, NH, USA.
Ackerman ME; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA .; Pokaż więcej
Źródło:: Molecular systems biology [Mol Syst Biol] 2018 Mar 26; Vol. 14 (3), pp. e7881. Date of Electronic Publication: 2018 Mar 26.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Viral/*analysis
HIV Infections/*immunology
HIV-1/*immunology
Complement Fixation Tests ; Computational Biology/methods ; Humans ; Immunity, Humoral ; Phagocytosis

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Skocz do pozycji: 7.

Tytuł:: Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.
Autorzy:: Ramsuran V; Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Naranbhai V; Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Horowitz A; Department of Oncological Sciences, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Qi Y; Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Martin MP; Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Yuki Y; Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Gao X; Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Walker-Sperling V; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
Del Prete GQ; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Schneider DK; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Fellay J; School of Life Sciences, École Polytechnique Fédérale de Lausanne, and Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Deeks SG; Department of Medicine University of California, San Francisco, CA 94143, USA.
Martin JN; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143, USA.
Goedert JJ; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20850, USA.
Wolinsky SM; Division of Infectious Diseases, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Michael NL; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Kirk GD; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Buchbinder S; Department of Medicine University of California, San Francisco, CA 94143, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143, USA.; San Francisco Department of Public Health, HIV Research Section, San Francisco, CA 94102, USA.
Haas D; Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Ndung'u T; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.; African Health Research Institute, Durban, South Africa.; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.; Max Planck Institute for Infection Biology, Berlin, Germany.
Goulder P; African Health Research Institute, Durban, South Africa.; Department of Paediatrics, University of Oxford, Oxford, UK.
Parham P; Departments of Structural Biology and Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
Walker BD; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.; African Health Research Institute, Durban, South Africa.; Institute for Medical and Engineering Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Carlson JM; Microsoft Research, Redmond, WA 98052, USA.
Carrington M; Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA. .; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2018 Jan 05; Vol. 359 (6371), pp. 86-90. Date of Electronic Publication: 2018 Jan 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV/*immunology
HIV Infections/*immunology
HLA Antigens/*metabolism
Killer Cells, Natural/*immunology
NK Cell Lectin-Like Receptor Subfamily C/*metabolism
Alleles ; CD4 Lymphocyte Count ; Cohort Studies ; HIV Infections/drug therapy ; HIV Infections/genetics ; HLA Antigens/genetics ; Humans ; Ligands ; NK Cell Lectin-Like Receptor Subfamily C/antagonists & inhibitors ; NK Cell Lectin-Like Receptor Subfamily C/genetics ; Protein Sorting Signals ; Viremia/immunology

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Skocz do pozycji: 8.

Tytuł:: Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities.
Autorzy:: Leitman EM; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.; Harvard Medical School, Boston, Massachusetts, United States of America.
Palmer CD; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Buus S; Laboratory of Experimental Immunology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Chen F; Department of Sexual Health, Royal Berkshire Hospital, Reading, United Kingdom.
Riddell L; Integrated Sexual Health Services, Northamptonshire Healthcare NHS Trust, Northampton, United Kingdom.
Sims S; Institute of Virology, University of Zurich, Zurich, Switzerland.
Klenerman P; NIHR Biomedical Research Centre, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Sáez-Cirión A; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
Walker BD; Harvard Medical School, Boston, Massachusetts, United States of America.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Hess PR; Immunology Program, Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, United States of America.
Altfeld M; Harvard Medical School, Boston, Massachusetts, United States of America.; Virus Immunology Unit, Heinrich-Pette-Institut, Hamburg, Germany.
Matthews PC; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.
Goulder PJR; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Oct 11; Vol. 12 (10), pp. e0184496. Date of Electronic Publication: 2017 Oct 11 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Protein Multimerization*
CD8-Positive T-Lymphocytes/*immunology
HIV Infections/*drug therapy
HIV Infections/*immunology
Ribosome Inactivating Proteins, Type 1/*therapeutic use
Antiviral Agents/pharmacology ; CD8-Positive T-Lymphocytes/drug effects ; Endocytosis/drug effects ; Humans ; Lymphocyte Depletion ; Saporins

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Skocz do pozycji: 9.

Tytuł:: T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.
Autorzy:: Thomas AS; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.
Jones KL; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.
Gandhi RT; Ragon Institute of MIT, MGH, and Harvard, Cambridge MA, United States of America.; Massachusetts General Hospital, Boston, Massachusetts, United States of America.
McMahon DK; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Cyktor JC; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Chan D; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.
Huang SH; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.
Truong R; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.
Bosque A; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.
Macedo AB; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.
Kovacs C; Maple Leaf Medical Clinic, Toronto, Canada.
Benko E; Division of Infectious Diseases, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.
Eron JJ; Division of Infectious Diseases, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America.
Bosch RJ; Harvard TH Chan School of Public Health, Boston, Massachusetts, United States of America.
Lalama CM; Harvard TH Chan School of Public Health, Boston, Massachusetts, United States of America.
Simmens S; Department of Epidemiology and Biostatistics, George Washington University, Milken Institute School of Public Health, Washington, District of Columbia, United States of America.
Walker BD; Ragon Institute of MIT, MGH, and Harvard, Cambridge MA, United States of America.; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Mellors JW; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Jones RB; Department of Microbiology Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2017 Sep 20; Vol. 13 (9), pp. e1006629. Date of Electronic Publication: 2017 Sep 20 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
HIV Infections/*immunology
Virus Latency/*immunology
nef Gene Products, Human Immunodeficiency Virus/*immunology
Anti-Retroviral Agents/therapeutic use ; Enzyme-Linked Immunospot Assay ; HIV Infections/drug therapy ; Humans ; Polymerase Chain Reaction

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Skocz do pozycji: 10.

Tytuł:: Increased frequencies of CD8 T cells are associated with antibody neutralization breadth against HIV in viraemic controllers.
Autorzy:: Palmer CD; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Romero-Tejeda M; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Scully EP; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Division of Infectious Diseases, Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Lockhart A; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Seaman MS; Beth Israel Deaconess Medical Center Boston, MA, USA.
Goldenthal A; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Piechocka-Trocha A; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
Chibnik LB; Program in Translational Neuropsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Jost S; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.
Porichis F; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA; .; Pokaż więcej
Źródło:: Journal of the International AIDS Society [J Int AIDS Soc] 2016 Dec 09; Vol. 19 (1), pp. 21136. Date of Electronic Publication: 2016 Dec 09 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: Antibodies, Neutralizing/*immunology
CD8-Positive T-Lymphocytes/*immunology
HIV Antibodies/*immunology
HIV Infections/*immunology
AIDS Vaccines/immunology ; Adult ; Antibodies, Neutralizing/blood ; CD4 Lymphocyte Count ; CD57 Antigens ; Female ; HIV Antibodies/blood ; HIV Infections/virology ; Humans ; Immunogenicity, Vaccine ; Leukocytes, Mononuclear ; Male ; Middle Aged ; Viral Load ; Viremia/immunology

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na półce

Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.
Autorzy:: Tully DC; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Ogilvie CB; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Batorsky RE; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Bean DJ; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Power KA; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Ghebremichael M; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Bedard HE; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Gladden AD; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Seese AM; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Amero MA; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Lane K; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
McGrath G; Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Bazner SB; Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Tinsley J; The Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America.
Lennon NJ; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Henn MR; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Brumme ZL; Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Norris PJ; Blood Systems Research Institute, San Francisco, California, United States of America.
Rosenberg ES; Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Mayer KH; The Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America.
Jessen H; HIV Clinic Praxis, Jessen, Berlin, Germany.
Kosakovsky Pond SL; Department of Medicine, University of California San Diego, La Jolla, California, United States of America.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Altfeld M; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.; Heinrich-Pette-Institut, Hamburg, Germany.
Carlson JM; Microsoft Research, Redmond, Washington, United States of America.
Allen TM; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2016 May 10; Vol. 12 (5), pp. e1005619. Date of Electronic Publication: 2016 May 10 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: HIV Infections/*transmission
HIV-1/*genetics
Evolution, Molecular ; Genetic Variation ; Genome, Viral ; HIV Envelope Protein gp120/genetics ; Humans ; Male ; Models, Theoretical ; Polymerase Chain Reaction ; Selection, Genetic/genetics

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Skocz do pozycji: 12.

Tytuł:: A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.
Autorzy:: Jones RB; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
Mueller S; Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts, United States of America.
O'Connor R; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Rimpel K; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Sloan DD; Gilead Sciences, Foster City, California, United States of America.
Karel D; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Wong HC; Altor BioScience Corporation, Miramar, Florida, United States of America.
Jeng EK; Altor BioScience Corporation, Miramar, Florida, United States of America.
Thomas AS; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
Whitney JB; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
Lim SY; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
Kovacs C; The Maple Leaf Medical Clinic, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Benko E; The Maple Leaf Medical Clinic, Toronto, Ontario, Canada.
Karandish S; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
Huang SH; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
Buzon MJ; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Lichterfeld M; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Irrinki A; Gilead Sciences, Foster City, California, United States of America.
Murry JP; Gilead Sciences, Foster City, California, United States of America.
Tsai A; Gilead Sciences, Foster City, California, United States of America.
Yu H; Gilead Sciences, Foster City, California, United States of America.
Geleziunas R; Gilead Sciences, Foster City, California, United States of America.
Trocha A; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Ostrowski MA; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Medical Institute, St. Michael's Hospital, Toronto, Ontario, Canad.
Irvine DJ; Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts, United States of America.; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.; Department of Biological Engineering, MIT, Cambridge, Massachusetts, United States of America.
Walker BD; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2016 Apr 15; Vol. 12 (4), pp. e1005545. Date of Electronic Publication: 2016 Apr 15 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antiviral Agents/*pharmacology
CD4-Positive T-Lymphocytes/*virology
HIV Infections/*immunology
Proteins/*pharmacology
T-Lymphocytes, Cytotoxic/*immunology
Virus Latency/*drug effects
Enzyme-Linked Immunosorbent Assay ; Enzyme-Linked Immunospot Assay ; Flow Cytometry ; Humans ; Polymerase Chain Reaction ; Recombinant Fusion Proteins ; Virus Activation/drug effects

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Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Structural Determinants of Antiretroviral Therapy Use, HIV Care Attendance, and Viral Suppression among Adolescents and Young Adults Living with HIV.
Autorzy:: Kahana SY; Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse/National Institutes of Health, Bethesda, MD, United States of America.
Jenkins RA; Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse/National Institutes of Health, Bethesda, MD, United States of America.
Bruce D; Department of Health Sciences, DePaul University, Chicago, IL, United States of America.
Fernandez MI; Department of Preventive Medicine and Department of Public Health Program, College of Osteopathic Medicine, Nova Southeastern University, Ft. Lauderdale, FL, United States of America.
Hightow-Weidman LB; Department of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Bauermeister JA; Department of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America.; Pokaż więcej
Corporate Authors:: Adolescent Medicine Trials Network for HIV/AIDS Interventions
Źródło:: PloS one [PLoS One] 2016 Apr 01; Vol. 11 (4), pp. e0151106. Date of Electronic Publication: 2016 Apr 01 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Health Behavior*
Anti-Retroviral Agents/*therapeutic use
HIV/*drug effects
HIV Infections/*drug therapy
HIV Infections/*epidemiology
Adolescent ; Black People ; Female ; Hispanic or Latino ; Humans ; Male ; Socioeconomic Factors ; United States/epidemiology ; Young Adult

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Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.
Autorzy:: Mahan AE; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Jennewein MF; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Suscovich T; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Dionne K; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Tedesco J; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Chung AW; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Streeck H; Military HIV Research Program, Walter Reed Medical Research Institute, Bethesda, Maryland, United States of America.
Pau M; Crucell, Leiden, Netherlands.
Schuitemaker H; Crucell, Leiden, Netherlands.; Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands.
Francis D; Global Solutions for Infectious Diseases, South San Francisco, California, United States of America.
Fast P; International AIDS Vaccine Initiative, New York, New York, United States of America.
Laufer D; International AIDS Vaccine Initiative, New York, New York, United States of America.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Baden L; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Barouch DH; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
Alter G; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2016 Mar 16; Vol. 12 (3), pp. e1005456. Date of Electronic Publication: 2016 Mar 16 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Vaccination*
Antibody-Dependent Cell Cytotoxicity/*immunology
HIV Antibodies/*immunology
HIV Antigens/*immunology
HIV Infections/*immunology
Cohort Studies ; Female ; Glycosylation ; HIV Antibodies/isolation & purification ; HIV Seropositivity ; Humans ; Immunoglobulin Fc Fragments/immunology ; Immunoglobulin G ; Male ; Phagocytosis

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Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control.
Autorzy:: Ackerman ME; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, United States of America.
Mikhailova A; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America.
Brown EP; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, United States of America.
Dowell KG; Department of Computer Science, Dartmouth College, Hanover, New Hampshire, United States of America.
Walker BD; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America.; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Bailey-Kellogg C; Department of Computer Science, Dartmouth College, Hanover, New Hampshire, United States of America.
Suscovich TJ; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America.
Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2016 Jan 08; Vol. 12 (1), pp. e1005315. Date of Electronic Publication: 2016 Jan 08 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Neutralizing/*immunology
HIV Antibodies/*immunology
HIV Infections/*immunology
Immunoglobulin G/*immunology
Antibody-Dependent Cell Cytotoxicity/immunology ; Humans ; Killer Cells, Natural/immunology ; Lymphocyte Activation/immunology

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Skocz do pozycji: 16.

Tytuł:: Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.
Autorzy:: Heesters BA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Lindqvist M; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America.; Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America.
Vagefi PA; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Scully EP; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
Schildberg FA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Altfeld M; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America.; Department of Viral Immunology, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Walker BD; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America.; Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America.
Kaufmann DE; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America.; Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America.; Centre de Recherché du CHUM; Department of Medicine, Université de Montréal, Montreal, Quebec, Canada.
Carroll MC; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2015 Dec 01; Vol. 11 (12), pp. e1005285. Date of Electronic Publication: 2015 Dec 01 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dendritic Cells, Follicular/*virology
Endosomes/*virology
HIV Infections/*immunology
Animals ; CD4-Positive T-Lymphocytes/immunology ; Humans ; Immunohistochemistry ; Mice ; Mice, Inbred C57BL ; Polymerase Chain Reaction

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Skocz do pozycji: 17.

Tytuł:: Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection.
Autorzy:: Mori M; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Adland E; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Paioni P; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Swordy A; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Mori L; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Laker L; Kimberley Hospital, Kimberley, Durban, South Africa.
Muenchhoff M; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Matthews PC; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Tudor-Williams G; Department of Paediatrics, Imperial College, London, United Kingdom.
Lavandier N; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
van Zyl A; Kimberley Hospital, Kimberley, Durban, South Africa.
Hurst J; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Boston, MA, United States of America; Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Ndung'u T; Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), University of KwaZulu-Natal, Durban, South Africa; Max Planck Institute for Infection Biology, Berlin, Germany.
Prendergast A; Centre for Paediatrics, Blizard Institute, Queen Mary University of London, London, United Kingdom.
Goulder P; Department of Paediatrics, University of Oxford, Oxford, United Kingdom; Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Jooste P; Kimberley Hospital, Kimberley, Durban, South Africa.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Jul 07; Vol. 10 (7), pp. e0131591. Date of Electronic Publication: 2015 Jul 07 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Retroviral Agents/*therapeutic use
HIV Infections/*drug therapy
Adolescent ; CD4 Lymphocyte Count ; Child ; Child, Preschool ; Cohort Studies ; Female ; HIV Infections/epidemiology ; HIV Infections/pathology ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; Severity of Illness Index ; Sex Factors ; South Africa/epidemiology ; Treatment Outcome ; Viral Load/drug effects

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Skocz do pozycji: 18.

Tytuł:: Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.
Autorzy:: Caskey M; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Klein F; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Lorenzi JC; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Seaman MS; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
West AP Jr; Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.
Buckley N; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Kremer G; 1] First Department of Internal Medicine, University Hospital of Cologne, D-50924 Cologne, Germany [2] Clinical Trials Center Cologne, ZKS Köln, BMBF 01KN1106, University of Cologne, Cologne, Germany.
Nogueira L; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Braunschweig M; 1] Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA [2] Albert Ludwigs University of Freiburg, 79085 Freiburg, Germany.
Scheid JF; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Horwitz JA; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Shimeliovich I; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Ben-Avraham S; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Witmer-Pack M; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Platten M; 1] First Department of Internal Medicine, University Hospital of Cologne, D-50924 Cologne, Germany [2] German Center for Infection Research (DZIF), partner site Bonn-Cologne, Cologne, Germany.
Lehmann C; 1] First Department of Internal Medicine, University Hospital of Cologne, D-50924 Cologne, Germany [2] German Center for Infection Research (DZIF), partner site Bonn-Cologne, Cologne, Germany.
Burke LA; 1] Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA [2] Division of Infectious Diseases, Weill Medical College of Cornell University, New York, New York 10065, USA.
Hawthorne T; Celldex Therapeutics, Inc., Hampton, New Jersey 08827, USA.
Gorelick RJ; AIDS and Cancer Virus Program, Leidos Biomedical Research, Frederick, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Howard Hughes Medical Institute, Massachusetts General Hospital and Harvard Medical School, Cambridge, Massachusetts 02139, USA.
Keler T; Celldex Therapeutics, Inc., Hampton, New Jersey 08827, USA.
Gulick RM; Division of Infectious Diseases, Weill Medical College of Cornell University, New York, New York 10065, USA.
Fätkenheuer G; 1] First Department of Internal Medicine, University Hospital of Cologne, D-50924 Cologne, Germany [2] German Center for Infection Research (DZIF), partner site Bonn-Cologne, Cologne, Germany.
Schlesinger SJ; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.
Nussenzweig MC; 1] Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA [2] Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10065, USA.; Pokaż więcej
Źródło:: Nature [Nature] 2015 Jun 25; Vol. 522 (7557), pp. 487-91. Date of Electronic Publication: 2015 Apr 08.
Typ publikacji:: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Neutralizing/*immunology
HIV Antibodies/*immunology
HIV Infections/*therapy
HIV-1/*immunology
Viral Load/*immunology
Viremia/*therapy
Adult ; Amino Acid Sequence ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/pharmacokinetics ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Humanized ; Antibodies, Neutralizing/administration & dosage ; Antibodies, Neutralizing/adverse effects ; Antibodies, Neutralizing/pharmacology ; Antibodies, Neutralizing/therapeutic use ; Binding Sites ; Broadly Neutralizing Antibodies ; CD4 Antigens/metabolism ; Case-Control Studies ; Evolution, Molecular ; Female ; HIV Antibodies/administration & dosage ; HIV Antibodies/adverse effects ; HIV Antibodies/pharmacology ; HIV Antibodies/therapeutic use ; HIV Envelope Protein gp120/chemistry ; HIV Envelope Protein gp120/immunology ; HIV Infections/immunology ; HIV Infections/virology ; HIV-1/chemistry ; HIV-1/drug effects ; Humans ; Immunization, Passive/methods ; Male ; Middle Aged ; Molecular Sequence Data ; Time Factors ; Viral Load/drug effects ; Viremia/immunology ; Viremia/virology ; Young Adult

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Skocz do pozycji: 19.

Tytuł:: Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection.
Autorzy:: Adland E; Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom.
Paioni P; Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom.
Thobakgale C; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Laker L; Paediatric Department, Kimberley Hospital, Northern Cape, South Africa.
Mori L; Paediatric Department, Kimberley Hospital, Northern Cape, South Africa.
Muenchhoff M; Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Csala A; Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom.
Clapson M; Department of Paediatric Infectious Diseases, Great Ormond St Hospital for Children, London, United Kingdom.
Flynn J; Department of Paediatric Infectious Diseases, Great Ormond St Hospital for Children, London, United Kingdom.
Novelli V; Department of Paediatric Infectious Diseases, Great Ormond St Hospital for Children, London, United Kingdom.
Hurst J; The Institute for Emerging Infections, The Oxford Martin School, University of Oxford, Oxford, United Kingdom; Nuffield Department of Medicine, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom; Oxford National Institute of Health Research, Biomedical Research Centre, Oxford, United Kingdom.
Naidoo V; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Shapiro R; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Huang KH; The Institute for Emerging Infections, The Oxford Martin School, University of Oxford, Oxford, United Kingdom; Nuffield Department of Medicine, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom.
Frater J; The Institute for Emerging Infections, The Oxford Martin School, University of Oxford, Oxford, United Kingdom; Nuffield Department of Medicine, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom; Oxford National Institute of Health Research, Biomedical Research Centre, Oxford, United Kingdom.
Prendergast A; Centre for Paediatrics, Blizard Institute, Queen Mary University of London, London, United Kingdom; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
Prado JG; AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona, Spain.
Ndung'u T; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; The Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard University, Boston, Massachusetts, United States of America; KwaZulu-Natal Research Institute for Tuberculosis and HIV, University of KwaZulu-Natal, Durban, South Africa; Max Planck Institute for Infection Biology, Berlin, Germany.
Walker BD; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; The Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard University, Boston, Massachusetts, United States of America.
Carrington M; The Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard University, Boston, Massachusetts, United States of America; Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America.
Jooste P; Paediatric Department, Kimberley Hospital, Northern Cape, South Africa.
Goulder PJ; Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; Department of Paediatric Infectious Diseases, Great Ormond St Hospital for Children, London, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2015 Jun 15; Vol. 11 (6), pp. e1004954. Date of Electronic Publication: 2015 Jun 15 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV Infections/*genetics
HIV-1/*physiology
HLA Antigens/*genetics
Virus Replication/*genetics
Adult ; Child ; Cohort Studies ; Disease Progression ; Humans ; Polymerase Chain Reaction

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Skocz do pozycji: 20.

Tytuł:: Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers.
Autorzy:: Martin-Gayo E; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Buzon MJ; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America; Infectious Disease Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Ouyang Z; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Hickman T; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Cronin J; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Pimenova D; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Lichterfeld M; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America; Infectious Disease Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Infectious Disease Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Yu XG; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2015 Jun 11; Vol. 11 (6), pp. e1004930. Date of Electronic Publication: 2015 Jun 11 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
Dendritic Cells/*immunology
HIV Infections/*immunology
HIV-1/*immunology
Immunity, Cellular/*immunology
Blotting, Western ; Flow Cytometry ; Gene Knockdown Techniques ; Humans ; Lymphocyte Culture Test, Mixed ; Polymerase Chain Reaction ; RNA, Small Interfering

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Skocz do pozycji: 21.

Tytuł:: Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma.
Autorzy:: Chen J; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, INF 324, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg. Germany.
Tibroni N; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, INF 324, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg. Germany.
Sauter D; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
Galaski J; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, INF 324, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg. Germany.
Miura T; Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Alter G; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, United States of America.
Mueller B; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, INF 324, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg. Germany.
Haller C; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, INF 324, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg. Germany.
Walker BD; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, United States of America; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Kirchhoff F; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
Brumme ZL; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Ueno T; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Kumamoto, Japan; International Research Center for Medical Sciences (IRCMS), Kumamoto University, Japan.
Fackler OT; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, INF 324, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg. Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Mar 20; Vol. 10 (3), pp. e0120434. Date of Electronic Publication: 2015 Mar 20 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alleles*
HIV Infections/*blood
HIV Infections/*virology
HIV-1/*genetics
Human Immunodeficiency Virus Proteins/*genetics
Viral Regulatory and Accessory Proteins/*genetics
Amino Acid Sequence ; CD4 Antigens/metabolism ; Cell Membrane/metabolism ; Conserved Sequence ; Disease Progression ; Down-Regulation/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Histocompatibility Antigens Class I/metabolism ; Human Immunodeficiency Virus Proteins/chemistry ; Humans ; Likelihood Functions ; Molecular Sequence Data ; NF-kappa B/metabolism ; Phylogeny ; RNA, Viral/blood ; Sequence Analysis, Protein ; Signal Transduction ; Viral Regulatory and Accessory Proteins/chemistry

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Skocz do pozycji: 22.

Tytuł:: Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.
Autorzy:: Jones RB; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
O'Connor R; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America.
Mueller S; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
Foley M; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
Szeto GL; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
Karel D; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America.
Lichterfeld M; Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Kovacs C; The Maple Leaf Medical Clinic, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Ostrowski MA; The Maple Leaf Medical Clinic, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Li Ka Shing Medical Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Trocha A; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America.
Irvine DJ; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Walker BD; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America; Massachusetts General Hospital, Boston, Massachusetts, United States of America; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2014 Aug 14; Vol. 10 (8), pp. e1004287. Date of Electronic Publication: 2014 Aug 14 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytotoxicity, Immunologic/*drug effects
Depsipeptides/*pharmacology
HIV Infections/*immunology
Histone Deacetylase Inhibitors/*pharmacology
Hydroxamic Acids/*pharmacology
Indoles/*pharmacology
T-Lymphocytes, Cytotoxic/*immunology
Cell Proliferation/drug effects ; Cell Survival/drug effects ; Humans ; Panobinostat ; T-Lymphocytes, Cytotoxic/drug effects ; Virus Replication/drug effects

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Skocz do pozycji: 23.

Tytuł:: Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic.
Autorzy:: Cotton LA; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Kuang XT; Department of Molecular Biology and Biochemistry, Faculty of Science, Simon Fraser University, Burnaby, British Columbia, Canada.
Le AQ; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Carlson JM; Microsoft Research, Los Angeles, California, United States of America.
Chan B; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Chopera DR; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa.
Brumme CJ; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Markle TJ; Department of Molecular Biology and Biochemistry, Faculty of Science, Simon Fraser University, Burnaby, British Columbia, Canada.
Martin E; Department of Molecular Biology and Biochemistry, Faculty of Science, Simon Fraser University, Burnaby, British Columbia, Canada; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Shahid A; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Anmole G; Department of Molecular Biology and Biochemistry, Faculty of Science, Simon Fraser University, Burnaby, British Columbia, Canada.
Mwimanzi P; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Nassab P; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Penney KA; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Rahman MA; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Milloy MJ; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Schechter MT; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Markowitz M; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York, United States of America.
Carrington M; Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America; Ragon Institute of MGH, MIT and Harvard University, Cambridge, Massachusetts, United States of America.
Walker BD; Ragon Institute of MGH, MIT and Harvard University, Cambridge, Massachusetts, United States of America.
Wagner T; San Francisco Department of Public Health, San Francisco, California, United States of America.
Buchbinder S; San Francisco Department of Public Health, San Francisco, California, United States of America.
Fuchs J; San Francisco Department of Public Health, San Francisco, California, United States of America.
Koblin B; New York Blood Center, New York, New York, United States of America.
Mayer KH; Fenway Community Health, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts, United States of America.
Harrigan PR; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Brockman MA; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada; Department of Molecular Biology and Biochemistry, Faculty of Science, Simon Fraser University, Burnaby, British Columbia, Canada; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Poon AF; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Brumme ZL; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2014 Apr 24; Vol. 10 (4), pp. e1004295. Date of Electronic Publication: 2014 Apr 24 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Adaptation, Physiological/*genetics
HIV Infections/*genetics
HIV-1/*genetics
Amino Acid Sequence ; Genotype ; HLA Antigens/genetics ; Humans ; Male ; Molecular Sequence Data ; North America ; Phylogeny ; Polymorphism, Genetic/genetics

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Skocz do pozycji: 24.

Tytuł:: LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.
Autorzy:: Bashirova AA; Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Martin-Gayo E; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Jones DC; Department of Pathology, Cambridge University, Cambridge, United Kingdom.
Qi Y; Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Apps R; Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Gao X; Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Burke PS; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Taylor CJ; Tissue Typing Laboratories, Addenbrookes Hospital, Cambridge, United Kingdom.
Rogich J; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Wolinsky S; Northwestern University Medical School, Chicago, Illinois, United States of America.
Bream JH; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Duggal P; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Hussain S; Fielding School of Public Health, University of California at Los Angeles, Los Angeles, California, United States of America.
Martinson J; University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Weintrob A; USU Infectious Disease Clinical Research Program, Bethesda, Maryland, United States of America.
Kirk GD; Johns Hopkins University School of Public Health, Baltimore, Maryland, United States of America.
Fellay J; School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Buchbinder SP; San Francisco Department of Public Health, San Francisco, California, United States of America.
Goedert JJ; Division of Cancer Epidemiology & Genetics, NCI, Bethesda, Maryland, United States of America.
Deeks SG; University of California at San Francisco Medical School, San Francisco, California, United States of America.
Pereyra F; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America; Infectious Disease Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Trowsdale J; Department of Pathology, Cambridge University, Cambridge, United Kingdom.
Lichterfeld M; Infectious Disease Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Telenti A; Institute of Microbiology, University Hospital and University of Lausanne, Lausanne, Switzerland.
Walker BD; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Allen RL; St George's Medical School, University of London, London, United Kingdom.
Carrington M; Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Yu XG; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2014 Mar 06; Vol. 10 (3), pp. e1004196. Date of Electronic Publication: 2014 Mar 06 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV Infections/*immunology
Histocompatibility Antigens Class I/*immunology
Immunity, Innate/*genetics
Membrane Glycoproteins/*genetics
Receptors, Immunologic/*genetics
Alleles ; CD8-Positive T-Lymphocytes/immunology ; Dendritic Cells/immunology ; Female ; HIV Infections/genetics ; HIV Infections/virology ; HIV-1/genetics ; HIV-1/immunology ; Histocompatibility Antigens Class I/genetics ; Humans ; Membrane Glycoproteins/immunology ; Receptors, Immunologic/immunology ; Viral Load/genetics ; Viral Load/immunology

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Skocz do pozycji: 25.

Tytuł:: High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function.
Autorzy:: Foley MH; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America ; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
Forcier T; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America ; Department of Material Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
McAndrew E; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Gonzalez M; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Chen H; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Juelg B; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
Walker BD; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America ; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
Irvine DJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America ; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America ; Department of Material Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America ; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Feb 13; Vol. 9 (2), pp. e87873. Date of Electronic Publication: 2014 Feb 13 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytotoxicity, Immunologic*
Antigens, Viral/*immunology
CD4 Antigens/*immunology
CD4-Positive T-Lymphocytes/*immunology
HIV Infections/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Antigens, Viral/genetics ; CD4 Antigens/genetics ; CD4-Positive T-Lymphocytes/pathology ; CD4-Positive T-Lymphocytes/virology ; CD58 Antigens/genetics ; CD58 Antigens/immunology ; Calcium/metabolism ; Cell Culture Techniques ; Cell Movement/immunology ; Gene Expression ; HIV/immunology ; HIV Infections/pathology ; HIV Infections/virology ; Humans ; Immunity, Cellular ; Lymphocyte Function-Associated Antigen-1/genetics ; Lymphocyte Function-Associated Antigen-1/immunology ; Signal Transduction/immunology ; T-Lymphocytes, Cytotoxic/pathology ; T-Lymphocytes, Cytotoxic/virology

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Skocz do pozycji: 26.

Tytuł:: HIV-1 persistence in CD4+ T cells with stem cell-like properties.
Autorzy:: Buzon MJ; 1] Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Sun H; 1] Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA. [2] Key Laboratory of AIDS Immunology, Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China.
Li C; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Shaw A; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Seiss K; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Ouyang Z; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Martin-Gayo E; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Leng J; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Henrich TJ; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Li JZ; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Pereyra F; 1] Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA. [2] Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Zurakowski R; Department of Electrical and Computer Engineering, University of Delaware, Newark, Delaware, USA.
Walker BD; 1] Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA. [2] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.
Rosenberg ES; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Yu XG; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Lichterfeld M; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Pokaż więcej
Źródło:: Nature medicine [Nat Med] 2014 Feb; Vol. 20 (2), pp. 139-42. Date of Electronic Publication: 2014 Jan 12.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Phylogeny*
Virus Latency*
CD4-Positive T-Lymphocytes/*virology
Disease Reservoirs/*virology
HIV Infections/*virology
HIV-1/*genetics
Lymphoid Progenitor Cells/*cytology
Antiretroviral Therapy, Highly Active ; Base Sequence ; Boston ; CD4-Positive T-Lymphocytes/cytology ; Cluster Analysis ; Evolution, Molecular ; Flow Cytometry ; HIV Infections/drug therapy ; Humans ; Molecular Sequence Data ; Reverse Transcriptase Polymerase Chain Reaction ; Sequence Analysis, DNA ; Species Specificity ; Statistics, Nonparametric ; env Gene Products, Human Immunodeficiency Virus/genetics

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Tytuł:: Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.
Autorzy:: Wong EB; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa ; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Akilimali NA; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa ; HIV Pathogenesis Programme, University of KwaZulu-Natal, Durban, South Africa.
Govender P; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa ; HIV Pathogenesis Programme, University of KwaZulu-Natal, Durban, South Africa.
Sullivan ZA; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa ; Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Cosgrove C; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Pillay M; HIV Pathogenesis Programme, University of KwaZulu-Natal, Durban, South Africa.
Lewinsohn DM; Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America ; Portland Veterans Administration Medical Center, Portland, Oregon, United States of America.
Bishai WR; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa ; Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Walker BD; HIV Pathogenesis Programme, University of KwaZulu-Natal, Durban, South Africa ; The Ragon Institute of MGH, Massachusetts Institute of Technology, and Harvard, Harvard Medical School, Cambridge, Massachusetts, United States of America.
Ndung'u T; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa ; HIV Pathogenesis Programme, University of KwaZulu-Natal, Durban, South Africa ; The Ragon Institute of MGH, Massachusetts Institute of Technology, and Harvard, Harvard Medical School, Cambridge, Massachusetts, United States of America ; Max Planck Institute for Infection Biology, Berlin, Germany.
Klenerman P; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Kasprowicz VO; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa ; HIV Pathogenesis Programme, University of KwaZulu-Natal, Durban, South Africa ; The Ragon Institute of MGH, Massachusetts Institute of Technology, and Harvard, Harvard Medical School, Cambridge, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Dec 31; Vol. 8 (12), pp. e83474. Date of Electronic Publication: 2013 Dec 31 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Immunity, Mucosal*
CD8-Positive T-Lymphocytes/*immunology
HIV Infections/*complications
HIV Infections/*immunology
NK Cell Lectin-Like Receptor Subfamily B/*metabolism
T-Lymphocyte Subsets/*immunology
Tuberculosis, Pulmonary/*complications
Tuberculosis, Pulmonary/*immunology
Adolescent ; Adult ; Anti-HIV Agents/therapeutic use ; Case-Control Studies ; Cohort Studies ; Cross-Sectional Studies ; Female ; HIV Infections/drug therapy ; Humans ; Latent Tuberculosis/complications ; Latent Tuberculosis/immunology ; Lymphocyte Count ; Male ; Middle Aged ; South Africa ; Young Adult

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Skocz do pozycji: 28.

Tytuł:: Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection.
Autorzy:: Vaidya SA
Streeck H
Beckwith N
Ghebremichael M
Pereyra F
Kwon DS
Addo MM
Rychert J
Routy JP
Jessen H
Kelleher AD
Hecht F
Sekaly RP
Carrington M
Walker BD
Allen TM
Rosenberg ES
Altfeld M; Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Boston, MA, USA. .; Pokaż więcej
Źródło:: Retrovirology [Retrovirology] 2013 Nov 18; Vol. 10, pp. 139. Date of Electronic Publication: 2013 Nov 18.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:: HIV Infections/*immunology
HIV Infections/*virology
HIV-1/*immunology
HLA-B Antigens/*immunology
Adult ; Amino Acid Substitution ; Female ; HLA-B Antigens/genetics ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Point Mutation ; Polymorphism, Genetic ; Time Factors ; Viral Load

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Tytuł:: Non-immunogenicity of overlapping gag peptides pulsed on autologous cells after vaccination of HIV infected individuals.
Autorzy:: Kløverpris HN; Department of Paediatrics, University of Oxford, Oxford, United Kingdom ; KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), Nelson R Mandela School of Medicine, University of Kwazulu-Natal, Durban, KwaZulu-Natal, South Africa ; Department of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Jackson A
Handley A
Hayes P
Gilmour J
Riddell L
Chen F
Atkins M
Boffito M
Walker BD
Ackland J
Sullivan M
Goulder P; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Oct 04; Vol. 8 (10), pp. e74389. Date of Electronic Publication: 2013 Oct 04 (Print Publication: 2013).
Typ publikacji:: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: AIDS Vaccines/*immunology
AIDS Vaccines/*therapeutic use
HIV Infections/*immunology
HIV Infections/*prevention & control
Adolescent ; Adult ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Female ; Humans ; Interferon-gamma/metabolism ; Male ; Middle Aged ; Young Adult

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Skocz do pozycji: 30.

Tytuł:: Unravelling the mechanisms of durable control of HIV-1.
Autorzy:: Walker BD; Ragon Institute of MGH, MIT and Harvard, Massachusetts General Hospital, Cambridge, Massachusetts 02139, USA. />Yu XG; Pokaż więcej
Źródło:: Nature reviews. Immunology [Nat Rev Immunol] 2013 Jul; Vol. 13 (7), pp. 487-98.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: HIV Infections/*genetics
HIV Infections/*immunology
HIV-1/*genetics
HIV-1/*immunology
Animals ; CD4-Positive T-Lymphocytes/immunology ; Disease Progression ; HIV Infections/virology ; Humans

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Skocz do pozycji: 31.

Tytuł:: Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control.
Autorzy:: Ranasinghe S; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Cutler S
Davis I
Lu R
Soghoian DZ
Qi Y
Sidney J
Kranias G
Flanders MD
Lindqvist M
Kuhl B
Alter G
Deeks SG
Walker BD
Gao X
Sette A
Carrington M
Streeck H; Pokaż więcej
Źródło:: Nature medicine [Nat Med] 2013 Jul; Vol. 19 (7), pp. 930-3. Date of Electronic Publication: 2013 Jun 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: CD4-Positive T-Lymphocytes/*immunology
Disease Resistance/*genetics
HIV Infections/*immunology
HIV-1/*immunology
Alleles ; Cells, Cultured ; Cohort Studies ; Disease Resistance/immunology ; Gene Frequency ; Genetic Association Studies ; Genetic Predisposition to Disease ; HIV Infections/blood ; HIV Infections/virology ; HIV-1/physiology ; HLA-DRB1 Chains/genetics ; HLA-DRB1 Chains/immunology ; HLA-DRB1 Chains/metabolism ; Humans ; Viral Load/genetics ; Viral Load/physiology ; Virus Replication/genetics ; Virus Replication/immunology

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Skocz do pozycji: 32.

Tytuł:: Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls.
Autorzy:: McLaren PJ; School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Coulonges C
Ripke S
van den Berg L
Buchbinder S
Carrington M
Cossarizza A
Dalmau J
Deeks SG
Delaneau O
De Luca A
Goedert JJ
Haas D
Herbeck JT
Kathiresan S
Kirk GD
Lambotte O
Luo M
Mallal S
van Manen D
Martinez-Picado J
Meyer L
Miro JM
Mullins JI
Obel N
O'Brien SJ
Pereyra F
Plummer FA
Poli G
Qi Y
Rucart P
Sandhu MS
Shea PR
Schuitemaker H
Theodorou I
Vannberg F
Veldink J
Walker BD
Weintrob A
Winkler CA
Wolinsky S
Telenti A
Goldstein DB
de Bakker PI
Zagury JF
Fellay J; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (7), pp. e1003515. Date of Electronic Publication: 2013 Jul 25.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Host-Pathogen Interactions*
Polymorphism, Single Nucleotide*
HIV Infections/*genetics
HIV-1/*physiology
Case-Control Studies ; Cohort Studies ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; HIV Infections/virology ; Humans ; White People

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Skocz do pozycji: 33.

Tytuł:: Alcohol use predicts sexual risk behavior with HIV-negative or partners of unknown status among young HIV-positive men who have sex with men.
Autorzy:: Bruce D; Master of Public Health Program, DePaul University, Chicago, IL, USA. />Kahana S
Harper GW
Fernández MI; Pokaż więcej
Corporate Authors:: ATN
Źródło:: AIDS care [AIDS Care] 2013; Vol. 25 (5), pp. 559-65. Date of Electronic Publication: 2012 Sep 13.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Homosexuality, Male*
Risk-Taking*
Alcohol Drinking/*adverse effects
HIV Infections/*psychology
HIV Seropositivity/*psychology
Sexual Behavior/*statistics & numerical data
Bisexuality ; Condoms/statistics & numerical data ; Humans ; Male ; Retrospective Studies ; Safe Sex ; Unsafe Sex ; Young Adult

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Skocz do pozycji: 34.

Tytuł:: Secrets of the HIV controllers: A rare group of HIV-positive individuals need no medicine to keep the virus in check. Their good fortune could point the way to more powerful treatments--and perhaps a vaccine.
Autorzy:: Walker BD; Ragon Institute, Boston, USA.; Pokaż więcej
Źródło:: Scientific American [Sci Am] 2012 Jul; Vol. 307 (1), pp. 44-51.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: HIV Seropositivity*/genetics
HIV Seropositivity*/immunology
HIV Infections/*immunology
AIDS Vaccines ; Acquired Immunodeficiency Syndrome/genetics ; Acquired Immunodeficiency Syndrome/immunology ; Acquired Immunodeficiency Syndrome/prevention & control ; Anti-HIV Agents/therapeutic use ; Female ; HIV/immunology ; HIV Infections/drug therapy ; HIV Infections/prevention & control ; Humans ; Male ; Natural Killer T-Cells/immunology ; T-Lymphocytes, Helper-Inducer/immunology

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Skocz do pozycji: 35.

Tytuł:: TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection.
Autorzy:: Chen H; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, USA.
Ndhlovu ZM
Liu D
Porter LC
Fang JW
Darko S
Brockman MA
Miura T
Brumme ZL
Schneidewind A
Piechocka-Trocha A
Cesa KT
Sela J
Cung TD
Toth I
Pereyra F
Yu XG
Douek DC
Kaufmann DE
Allen TM
Walker BD; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2012 Jun 10; Vol. 13 (7), pp. 691-700. Date of Electronic Publication: 2012 Jun 10.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV Infections/*immunology
HIV-1/*immunology
HLA-B Antigens/*immunology
HLA-B27 Antigen/*immunology
Receptors, Antigen, T-Cell/*immunology
CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/virology ; Cells, Cultured ; Epitopes, T-Lymphocyte/immunology ; HIV Infections/blood ; HIV Infections/virology ; HIV Long-Term Survivors ; Humans ; Perforin/immunology ; Virus Replication/immunology ; gag Gene Products, Human Immunodeficiency Virus/immunology

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Skocz do pozycji: 36.

Tytuł:: Understanding appraisal processes underlying the thentest: a mixed methods investigation.
Autorzy:: Schwartz CE; DeltaQuest Foundation, Inc., 31 Mitchell Road, Concord, MA 01742, USA. />Rapkin BD; Pokaż więcej
Źródło:: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation [Qual Life Res] 2012 Apr; Vol. 21 (3), pp. 381-8. Date of Electronic Publication: 2011 Oct 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Quality of Life*
Sickness Impact Profile*
HIV Infections/*psychology
Algorithms ; Factor Analysis, Statistical ; Female ; Health Services Research ; Humans ; Interviews as Topic ; Male ; Mental Recall ; Middle Aged ; Psychometrics ; Reproducibility of Results ; Research Design

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Skocz do pozycji: 37.

Tytuł:: Factors predicting discordant virological and immunological responses to antiretroviral therapy in HIV-1 clade C infected Zulu/Xhosa in South Africa.
Autorzy:: Julg B; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America. />Poole D
Ghebremichael M
Castilla C
Altfeld M
Sunpath H
Murphy RA
Walker BD; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e31161. Date of Electronic Publication: 2012 Feb 14.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-HIV Agents/*therapeutic use
HIV Infections/*drug therapy
Adult ; Age Factors ; Aged ; Antiretroviral Therapy, Highly Active/methods ; CD4 Lymphocyte Count ; Ethnicity ; HIV Infections/epidemiology ; HIV-1/isolation & purification ; Humans ; Middle Aged ; Prognosis ; Risk Factors ; South Africa ; Treatment Outcome ; Young Adult