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Wyświetlanie 61-80 z 4405
Tytuł:
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents.
Autorzy:
Poliseno V; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.; Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.
Chaves S; Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.
Brunetti L; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Loiodice F; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Carrieri A; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Laghezza A; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Tortorella P; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Magalhães JD; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cardoso SM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Institute of Molecular and Cell Biology, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
Santos MA; Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.
Piemontese L; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
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Źródło:
Biomolecules [Biomolecules] 2021 Jan 15; Vol. 11 (1). Date of Electronic Publication: 2021 Jan 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease/*drug therapy
Tenuazonic Acid/*therapeutic use
Alzheimer Disease/pathology ; Amyloid beta-Peptides/toxicity ; Cell Line, Tumor ; Cell Survival/drug effects ; Cholinesterase Inhibitors/pharmacology ; Donepezil/chemistry ; Donepezil/pharmacology ; Donepezil/therapeutic use ; Free Radical Scavengers/pharmacology ; Humans ; Hydrogen-Ion Concentration ; Metals/chemistry ; Molecular Docking Simulation ; Neuroprotection/drug effects ; Neuroprotective Agents/pharmacology ; Protein Aggregates/drug effects ; Spectrophotometry ; Tenuazonic Acid/chemistry ; Tenuazonic Acid/pharmacokinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-Inflammatory and Neuromodulatory Effects Induced by Tanacetum parthenium Water Extract: Results from In Silico, In Vitro and Ex Vivo Studies.
Autorzy:
Recinella L; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Chiavaroli A; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
di Giacomo V; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Antolini MD; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Acquaviva A; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.; Veridia Italia Srl, via Raiale 285, 65100 Pescara, Italy.
Leone S; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Brunetti L; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Menghini L; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Ak G; Department of Biology, Science Faculty, Selcuk University, Campus, 42130 Konya, Turkey.
Zengin G; Department of Biology, Science Faculty, Selcuk University, Campus, 42130 Konya, Turkey.
Di Simone SC; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Ferrante C; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Orlando G; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Dec 23; Vol. 26 (1). Date of Electronic Publication: 2020 Dec 23.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Cytokines/*metabolism
Gene Expression Regulation/*drug effects
Hypothalamus/*drug effects
Plant Extracts/*pharmacology
Tanacetum parthenium/*chemistry
Water/*chemistry
Animals ; Computer Simulation ; Cytokines/genetics ; Gene Expression Profiling ; Hypothalamus/metabolism ; In Vitro Techniques ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of tocilizumab administration on mortality in severe COVID-19.
Autorzy:
Tsai A; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ, 08876, USA.
Diawara O; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ, 08876, USA.
Nahass RG; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ, 08876, USA.; IDCare, 105 Raider Blvd, Hillsborough, NJ, 08844, USA.
Brunetti L; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ, 08876, USA. brunetti@pharmacy.rutgers.edu.; Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ, 08854, USA. brunetti@pharmacy.rutgers.edu.; Center of Excellence in Pharmaceutical Translational Research and Education, 160 Frelinghuysen Road, Piscataway, NJ, 08854, USA. brunetti@pharmacy.rutgers.edu.
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 05; Vol. 10 (1), pp. 19131. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji:
Journal Article
MeSH Terms:
Hospital Mortality*
Antibodies, Monoclonal, Humanized/*administration & dosage
Antibodies, Monoclonal, Humanized/*pharmacology
Coronavirus Infections/*drug therapy
Coronavirus Infections/*mortality
Pneumonia, Viral/*drug therapy
Pneumonia, Viral/*mortality
Antibodies, Monoclonal, Humanized/therapeutic use ; COVID-19 ; Female ; Humans ; Male ; Middle Aged ; Pandemics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors.
Autorzy:
Brunetti L; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Carrieri A; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Piemontese L; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Tortorella P; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Loiodice F; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Laghezza A; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 24; Vol. 21 (19). Date of Electronic Publication: 2020 Sep 24.
Typ publikacji:
Journal Article
MeSH Terms:
Enzyme Inhibitors*/chemical synthesis
Enzyme Inhibitors*/pharmacology
Amidohydrolases/*antagonists & inhibitors
PPAR alpha/*agonists
PPAR delta/*agonists
PPAR gamma/*agonists
Amidohydrolases/metabolism ; Hep G2 Cells ; Humans ; Ligands
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Colchicine to Weather the Cytokine Storm in Hospitalized Patients with COVID-19.
Autorzy:
Brunetti L; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ 08876, USA.; Ernest Mario School of Pharmacy, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA.; Center of Excellence in Pharmaceutical Translational Research and Education, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA.
Diawara O; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ 08876, USA.
Tsai A; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ 08876, USA.
Firestein BL; Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Nahass RG; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ 08876, USA.; IDCare, Hillsborough, NJ 08844, USA.
Poiani G; Robert Wood Johnson University Hospital Somerset, 110 Rehill Avenue, Somerville, NJ 08876, USA.; Division of Pulmonary/Critical Care Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
Schlesinger N; Division of Rheumatology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
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Źródło:
Journal of clinical medicine [J Clin Med] 2020 Sep 14; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 14.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Development and Characterization of Liquisolid Tablets Based on Mesoporous Clays or Silicas for Improving Glyburide Dissolution.
Autorzy:
Cirri M; Department of Chemistry, University of Florence, via Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Mura P; Department of Chemistry, University of Florence, via Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Valleri M; Menarini Manufacturing Logistics and Services, s.r.l. (AMMLS), 50019 Florence, Italy.
Brunetti L; Department of Chemistry, University of Florence, via Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
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Źródło:
Pharmaceutics [Pharmaceutics] 2020 Jun 01; Vol. 12 (6). Date of Electronic Publication: 2020 Jun 01.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy.
Autorzy:
Laghezza A; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Piemontese L; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Brunetti L; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Caradonna A; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Agamennone M; Department of Pharmacy, University 'G. d'Annunzio' of Chieti-Pescara, Via Dei Vestini, 31, 66100 Chieti, Italy.
Di Pizio A; Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Lise-Meitner-Str. 34, 85354 Freising, Germany.
Pochetti G; Istituto di Cristallografia, Consiglio Nazionale delle Ricerche, Montelibretti, Monterotondo Stazione, 00015 Roma, Italy.
Montanari R; Istituto di Cristallografia, Consiglio Nazionale delle Ricerche, Montelibretti, Monterotondo Stazione, 00015 Roma, Italy.
Capelli D; Istituto di Cristallografia, Consiglio Nazionale delle Ricerche, Montelibretti, Monterotondo Stazione, 00015 Roma, Italy.
Tauro M; Tumor Biology Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Loiodice F; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
Tortorella P; Department of Pharmacy and Pharmaceutical Sciences, University of Bari 'A. Moro', via E. Orabona 4, 70125 Bari, Italy.
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Źródło:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2020 Jun 01; Vol. 13 (6). Date of Electronic Publication: 2020 Jun 01.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phytochemical Analysis, Network Pharmacology and in Silico Investigations on Anacamptis pyramidalis Tuber Extracts.
Autorzy:
Mahomoodally MF; Department for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City 758307, Vietnam.; Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City 758307, Vietnam.
Picot-Allain MCN; Department of Health Sciences, Faculty of Science, University of Mauritius, Réduit 230, Mauritius.
Zengin G; Department of Biology, Science Faculty, Selcuk University, Campus, Konya 42130, Turkey.
Llorent-Martínez EJ; Department of Physical and Analytical Chemistry, University of Jaén, Campus Las Lagunillas S/N, E-23071 Jaén, Spain.
Abdullah HH; Chemistry Department, College of Education, Salahaddin University-Erbil, 44001 Erbil, Iraq.
Ak G; Department of Biology, Science Faculty, Selcuk University, Campus, Konya 42130, Turkey.
Senkardes I; Department of Pharmaceutical Botany, Faculty of Pharmacy, Marmara University, 34668 Istanbul, Turkey.
Chiavaroli A; Department of Pharmacy, 'G. d'Annunzio' University Chieti-Pescara, 66100 Chieti, Italy.
Menghini L; Department of Pharmacy, 'G. d'Annunzio' University Chieti-Pescara, 66100 Chieti, Italy.
Recinella L; Department of Pharmacy, 'G. d'Annunzio' University Chieti-Pescara, 66100 Chieti, Italy.
Brunetti L; Department of Pharmacy, 'G. d'Annunzio' University Chieti-Pescara, 66100 Chieti, Italy.
Leone S; Department of Pharmacy, 'G. d'Annunzio' University Chieti-Pescara, 66100 Chieti, Italy.
Orlando G; Department of Pharmacy, 'G. d'Annunzio' University Chieti-Pescara, 66100 Chieti, Italy.
Ferrante C; Department of Pharmacy, 'G. d'Annunzio' University Chieti-Pescara, 66100 Chieti, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 May 22; Vol. 25 (10). Date of Electronic Publication: 2020 May 22.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*pharmacology
Glycoside Hydrolase Inhibitors/*pharmacology
Orchidaceae/*chemistry
Phytochemicals/*chemistry
Alzheimer Disease/drug therapy ; Antioxidants/chemistry ; Computer Simulation ; Diabetes Mellitus, Type 2/drug therapy ; Glycoside Hydrolase Inhibitors/chemistry ; Horticulture/methods ; Humans ; Hyperpigmentation/drug therapy ; Methanol/chemistry ; Molecular Docking Simulation ; Monophenol Monooxygenase/antagonists & inhibitors ; Monophenol Monooxygenase/chemistry ; Phytochemicals/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Skin Diseases/drug therapy ; alpha-Amylases/antagonists & inhibitors ; alpha-Amylases/chemistry ; alpha-Glucosidases/chemistry ; alpha-Glucosidases/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antioxidant and Neuroprotective Effects Induced by Cannabidiol and Cannabigerol in Rat CTX-TNA2 Astrocytes and Isolated Cortexes.
Autorzy:
di Giacomo V; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Chiavaroli A; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Recinella L; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Orlando G; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Cataldi A; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Rapino M; Genetic Molecular Institute of CNR, Unit of Chieti, 'G. d' Annunzio' University, Via dei Vestini 31, 66100 Chieti-Pescara, Italy.
Di Valerio V; Department of Medicine and Ageing Sciences, 'G. d' Annunzio' University, Via dei Vestini 31, 66100 Chieti-Pescara, Italy..
Ronci M; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Leone S; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Brunetti L; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Menghini L; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
Zengin G; Department of Biology, Science Faculty, Selcuk University, Campus, 42130 Konya, Turkey.
Ak G; Department of Biology, Science Faculty, Selcuk University, Campus, 42130 Konya, Turkey.
Abdallah HH; Chemistry department, College of education, Salahaddin University-Erbil, Erbil 44001, Iraq.; School of Pharmaceutical Sciences, University Sains Malaysia, USM, Penang 11800, Malaysia.
Ferrante C; Department of Pharmacy, Università degli Studi 'Gabriele d'Annunzio', via dei Vestini 31, 66100 Chieti, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 May 18; Vol. 21 (10). Date of Electronic Publication: 2020 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*pharmacology
Astrocytes/*drug effects
Cannabidiol/*pharmacology
Cannabinoids/*pharmacology
Cerebral Cortex/*metabolism
Neuroprotective Agents/*pharmacology
Animals ; Apoptosis ; Astrocytes/metabolism ; Astrocytes/physiology ; Cerebral Cortex/physiology ; Oxidative Stress ; Proteomics ; Rats ; Serotonin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 61-80 z 4405

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