CDK9 inhibition induces epigenetic reprogramming revealing strategies to circumvent resistance in lymphoma.
Autorzy:
Thieme E; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. BrussN; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. Sun D; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA.; Present address: School of Mathematics, Shandong University, Jinan, 250100, Shandong, China. Dominguez EC; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. Coleman D; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. Liu T; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. Roleder C; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. Martinez M; Translational Genomics Research Institute, Phoenix, AZ, 85004, USA.; Integrated Mass Spectrometry Shared Resource, City of Hope National Medical Center, Duarte, CA, USA. Garcia-Mansfield K; Translational Genomics Research Institute, Phoenix, AZ, 85004, USA.; Integrated Mass Spectrometry Shared Resource, City of Hope National Medical Center, Duarte, CA, USA. Ball B; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. Pirrotte P; Translational Genomics Research Institute, Phoenix, AZ, 85004, USA.; Integrated Mass Spectrometry Shared Resource, City of Hope National Medical Center, Duarte, CA, USA. Wang L; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. Xia Z; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.; Biomedical Engineering Department, Oregon Health & Science University, Portland, OR, USA. Danilov AV; City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Mar 30; Vol. 22 (1), pp. 64. Date of Electronic Publication: 2023 Mar 30.
Pharmacologic inhibition of the ubiquitin-activating enzyme induces ER stress and apoptosis in chronic lymphocytic leukemia and ibrutinib-resistant mantle cell lymphoma cells.
Autorzy:
Best S; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA. Liu T; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA. BrussN; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA. Kittai A; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA. Berger A; Millennium Pharmaceuticals Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA, USA. Danilov AV; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2019 Dec; Vol. 60 (12), pp. 2946-2950. Date of Electronic Publication: 2019 May 21.
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