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Tytuł :
Deep Sequencing of Small RNAs from Neurosurgical Extracellular Vesicles Substantiates miR-486-3p as a Circulating Biomarker that Distinguishes Glioblastoma from Lower-Grade Astrocytoma Patients.
Autorzy :
Hallal S; Department of Neurosurgical Services, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney 2006, Australia.; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Ebrahim Khani S; Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney 2006, Australia.
Wei H; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Lee MYT; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Sim HW; Department of Medical Oncology and NHMRC Clinical Trials Centre, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; Central Clinical School, The University of Sydney, Sydney 2006, Australia.; The Kinghorn Cancer Centre, St Vincent's Hospital, Darlinghurst 2010, Australia.
Sy J; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Shivalingam B; Department of Neurosurgical Services, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.
Buckland ME; Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney 2006, Australia.; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Alexander-Kaufman KL; Department of Neurosurgical Services, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney 2006, Australia.; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 13; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A Comprehensive Proteomic SWATH-MS Workflow for Profiling Blood Extracellular Vesicles: A New Avenue for Glioma Tumour Surveillance.
Autorzy :
Hallal S; Neurosurgery Department, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney 2006, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Azimi A; Dermatology Department, School of Medical Sciences, The University of Sydney, Westmead 2145, Australia.
Wei H; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Ho N; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.
Lee MYT; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Sim HW; Department of Medical Oncology, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; NHMRC Clinical Trials Centre, University of Sydney, Camperdown 2050, Australia.; The Kinghorn Cancer Centre, St Vincent's Hospital, Darlinghurst 2010, Australia.
Sy J; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Shivalingam B; Neurosurgery Department, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.
Buckland ME; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney 2006, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
Alexander-Kaufman KL; Neurosurgery Department, Chris O'Brien Lifehouse, Camperdown 2050, Australia.; Brainstorm Brain Cancer Research, Brain and Mind Centre, The University of Sydney, Camperdown 2050, Australia.; Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney 2006, Australia.; Neuropathology Department, Royal Prince Alfred Hospital, Camperdown 2050, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 03; Vol. 21 (13). Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Concentrations of toxic metals and essential trace elements vary among individual neurons in the human locus ceruleus.
Autorzy :
Pamphlett R; Discipline of Pathology, Sydney Medical School, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Sydney, New South Wales, Australia.
Mak R; School of Chemistry and Sydney Analytical, The University of Sydney, Sydney, New South Wales, Australia.
Lee J; School of Chemistry and Sydney Analytical, The University of Sydney, Sydney, New South Wales, Australia.
Buckland ME; Discipline of Pathology, Sydney Medical School, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Sydney, New South Wales, Australia.
Harding AJ; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Sydney, New South Wales, Australia.
Kum Jew S; Discipline of Pathology, Sydney Medical School, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
Paterson DJ; Australian Synchrotron, Clayton, Victoria, Australia.
Jones MWM; Australian Synchrotron, Clayton, Victoria, Australia.
Lay PA; School of Chemistry and Sydney Analytical, The University of Sydney, Sydney, New South Wales, Australia.
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Źródło :
PloS one [PLoS One] 2020 May 19; Vol. 15 (5), pp. e0233300. Date of Electronic Publication: 2020 May 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Locus Coeruleus/*metabolism
Metals, Heavy/*analysis
Neurons/*metabolism
Trace Elements/*analysis
Aged ; Autopsy ; Female ; Heavy Metal Poisoning ; Humans ; Locus Coeruleus/physiology ; Middle Aged ; Motor Neurons/metabolism ; Multiple Sclerosis/metabolism ; Spectrometry, X-Ray Emission/methods ; Spinal Cord
Czasopismo naukowe
Tytuł :
MK2 Inhibition Induces p53-Dependent Senescence in Glioblastoma Cells.
Autorzy :
Phoa AF; School of Medical Sciences, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
Recasens A; School of Medical Sciences, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
Gurgis FMS; School of Medical Sciences, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
Betts TA; School of Medical Sciences, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
Menezes SV; School of Medical Sciences, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
Chau D; Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3050, Australia.
Nordfors K; Department of Pediatrics, Tampere University Hospital, 33521 Tampere, Finland.; Tampere Center for Child Health Research, University of Tampere, 33014 Tampere, Finland.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Haapasalo J; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.; Department of Pathology, Fimlab Laboratories, Tampere University Hospital, FI-33521 Tampere, Finland.
Haapasalo H; Department of Pathology, Fimlab Laboratories, Tampere University Hospital, FI-33521 Tampere, Finland.
Johns TG; Oncogenic Signalling Laboratory, Telethon Kids Institute, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA 6009, Australia.
Stringer BW; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD 4006, Australia.
Day BW; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD 4006, Australia.
Buckland ME; School of Medical Sciences, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.; Brain and Mind Research Institute, The University of Sydney, NSW 2006, Australia.
Lalaoui N; Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3050, Australia.
Munoz L; School of Medical Sciences, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
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Źródło :
Cancers [Cancers (Basel)] 2020 Mar 11; Vol. 12 (3). Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Corticomotor correlates of somatosensory reaction time and variability in individuals with post concussion symptoms.
Autorzy :
Pearce AJ; College of Health Science and Engineering, La Trobe University, Melbourne, Australia.
Kidgell DJ; Faculty of Medicine Nursing and Health Science, Monash University, Melbourne, Australia.
Frazer AK; Faculty of Medicine Nursing and Health Science, Monash University, Melbourne, Australia.
King DA; Faculty of Health and Environmental Science, Auckland University of Technology, Auckland, New Zealand.
Buckland ME; Department of Neuropathology, Royal Prince Alfred Hospital, Sydney, Australia.; Brain and Mind Centre, University Sydney, Camperdown, Australia.
Tommerdahl M; Cortical Metrics, USA.; Department of Biomedical Engineering, University of North Carolina, NC, USA.
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Źródło :
Somatosensory & motor research [Somatosens Mot Res] 2020 Mar; Vol. 37 (1), pp. 14-21. Date of Electronic Publication: 2019 Dec 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Chronic traumatic encephalopathy in a former Australian rules football player diagnosed with Alzheimer's disease.
Autorzy :
Pearce AJ; College of Science, Health and Engineering, La Trobe University, Bundoora, VIC, 3086, Australia.
Sy J; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia.
Lee M; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia.; Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia.
Harding A; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia.; Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia.
Mobbs R; Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia.; Macquarie University, Macquarie Park, NSW, 2109, Australia.
Batchelor J; Macquarie University, Macquarie Park, NSW, 2109, Australia.
Suter CM; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia.
Buckland ME; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia. michael.buckland@sydney.edu.au.; Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia. michael.buckland@sydney.edu.au.
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Źródło :
Acta neuropathologica communications [Acta Neuropathol Commun] 2020 Feb 26; Vol. 8 (1), pp. 23. Date of Electronic Publication: 2020 Feb 26.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
Raport
Tytuł :
Serum Exosome MicroRNAs Predict Multiple Sclerosis Disease Activity after Fingolimod Treatment.
Autorzy :
Ebrahimkhani S; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.
Beadnall HN; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.; Department of Neurology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Wang C; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.
Suter CM; Division of Molecular Structural and Computational Biology, Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.; Faculty of Medicine, University of New South Wales (UNSW Sydney), Kensington, NSW, Australia.
Barnett MH; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.; Department of Neurology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Buckland ME; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.
Vafaee F; School of Biotechnology and Biomolecular Sciences, University of New South Wales (UNSW Sydney), 2106, L2 West, Bioscience South E26, UNSW, Sydney, NSW, 2052, Australia. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2020 Feb; Vol. 57 (2), pp. 1245-1258. Date of Electronic Publication: 2019 Nov 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Driving innovation through collaboration: development of clinical annotation datasets for brain cancer biobanking.
Autorzy :
Gedye C; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; Clinical Research Director, NSW Health Statewide Biobank, Camperdown NSW.; School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.; Calvary Mater Newcastle, Waratah, NSW, Australia.
Sachchithananthan M; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.
Leonard R; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.
Jeffree RL; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; Royal Brisbane and Women's Hospital, University of Queensland, Australia.
Buckland ME; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.; Discipline of Pathology, Brain & Mind Centre, University of Sydney, NSW, Australia.
Ziegler DS; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia.; School of Women's and Children's Health, University of New South Wales, Sydney, Australia.; Children's Cancer Institute, University of New South Wales, Sydney, Australia.
Graeber MB; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; Brain Tumor Research Laboratories, Brain and Mind Centre, The University of Sydney, NSW, Australia.
Day BW; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
McDonald KL; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; Cure Brain Cancer Neuro-oncology Laboratory, Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.; Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.
Lasocki A; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; Department of Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
Nowak AK; Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.; School of Medicine and Pharmacology, University of Western Australia, Crawley.; Department of Medical Oncology, Sir Charles Gairdner Hospital, Nedlands, Australia.
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Corporate Authors :
BCBA Consortium
Źródło :
Neuro-oncology practice [Neurooncol Pract] 2020 Jan; Vol. 7 (1), pp. 31-37. Date of Electronic Publication: 2019 Aug 27.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
CD8 T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
Autorzy :
Gross CC; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany. .
Meyer C; Centre de Physiopathologie Toulouse-Purpan (CPTP), Université de Toulouse, CNRS, Inserm, UPS, CHU Purpan - BP 3028 - 31024, Toulouse Cedex 3, Toulouse, France.
Bhatia U; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Yshii L; Centre de Physiopathologie Toulouse-Purpan (CPTP), Université de Toulouse, CNRS, Inserm, UPS, CHU Purpan - BP 3028 - 31024, Toulouse Cedex 3, Toulouse, France.
Kleffner I; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.; Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum, In der Schornau 23-25, 44892, Bochum, Germany.
Bauer J; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria.
Tröscher AR; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria.
Schulte-Mecklenbeck A; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Herich S; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Schneider-Hohendorf T; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Plate H; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Kuhlmann T; Institute of Neuropathology, University Hospital Münster, University of Münster, Pottkamp 2, 48149, Münster, Germany.
Schwaninger M; Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Brück W; Institute of Neuropathology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37099, Göttingen, Germany.
Pawlitzki M; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Laplaud DA; UMR 1064, INSERM, Centre de Recherche en Transplantation et Immunologie, Université de Nantes, CHU Nantes - Hôtel Dieu Bd Jean Monnet, 44093, Nantes Cedex 01, France.; Service Neurologie, CHU Nantes, Nantes, France.
Loussouarn D; Service d'Anatomo-Pathologie, CHU Nantes, Hôtel-Dieu, rez-de-jardin, 44093, Nantes Cedex 1, France.
Parratt J; Department of Neurology, Royal North Shore Hospital, Sydney, Australia.; Australia Northern Clinical School, University of Sydney, Reserve Road, St Leonards, Sydney, NSW, 2065, Australia.
Barnett M; Brain and Mind Centre, Medical Faculty, University of Sydney, Mallett Street, Camperdown, Sydney, NSW, 2050, Australia.
Buckland ME; Brain and Mind Centre, Medical Faculty, University of Sydney, Mallett Street, Camperdown, Sydney, NSW, 2050, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, 94, Mallett Street, Camperdown, Sydney, NSW, 2050, Australia.
Hardy TA; Brain and Mind Centre, Medical Faculty, University of Sydney, Mallett Street, Camperdown, Sydney, NSW, 2050, Australia.; Department of Neurology, Concord Hospital, University of Sydney, Sydney, NSW, 2139, Australia.
Reddel SW; Brain and Mind Centre, Medical Faculty, University of Sydney, Mallett Street, Camperdown, Sydney, NSW, 2050, Australia.; Department of Neurology, Concord Hospital, University of Sydney, Sydney, NSW, 2139, Australia.
Ringelstein M; Department of Neurology, Medical Faculty, Heinrich Heine University, Moorenstraße 5, 40225, Düsseldorf, Germany.; Department of Neurology, Center of Neurology und Neuropsychiatry, LVR-Klinikum, Heinrich Heine University Düsseldorf, Bergische Landstraße 2, 40629, Düsseldorf, Germany.
Dörr J; Max Delbrueck Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, NeuroCure, Experimental and Clinical Research Center, Charitéplatz 1, 10117, Berlin, Germany.
Wildemann B; Molecular Neuroimmunology Group, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Kraemer M; Department of Neurology, Medical Faculty, Heinrich Heine University, Moorenstraße 5, 40225, Düsseldorf, Germany.; Department of Neurology, Alfried Krupp Hospital, Alfried-Krupp-Strasse 21, 45130, Essen, Germany.
Lassmann H; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria.
Höftberger R; Institute of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Beltrán E; Institute of Clinical Neuroimmunology, Biomedical Center and Hospital of the Ludwig-Maximilians-University Munich, Großhaderner Straße 9, Martinsried, 82152, Munich, Germany.
Dornmair K; Institute of Clinical Neuroimmunology, Biomedical Center and Hospital of the Ludwig-Maximilians-University Munich, Großhaderner Straße 9, Martinsried, 82152, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Schwab N; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Klotz L; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Meuth SG; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.; Cells in Motion (CiM), Münster, Germany.
Martin-Blondel G; Centre de Physiopathologie Toulouse-Purpan (CPTP), Université de Toulouse, CNRS, Inserm, UPS, CHU Purpan - BP 3028 - 31024, Toulouse Cedex 3, Toulouse, France.; Department of Infectious and Tropical Diseases, Toulouse University Hospital, Toulouse, France.
Wiendl H; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany. .; Australia Northern Clinical School, University of Sydney, Reserve Road, St Leonards, Sydney, NSW, 2065, Australia. .; Cells in Motion (CiM), Münster, Germany. .
Liblau R; Centre de Physiopathologie Toulouse-Purpan (CPTP), Université de Toulouse, CNRS, Inserm, UPS, CHU Purpan - BP 3028 - 31024, Toulouse Cedex 3, Toulouse, France. .
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Źródło :
Nature communications [Nat Commun] 2019 Dec 18; Vol. 10 (1), pp. 5779. Date of Electronic Publication: 2019 Dec 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Central Nervous System/*blood supply
Endothelium, Vascular/*pathology
Microvessels/*pathology
Susac Syndrome/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Adult ; Animals ; Cell Adhesion/drug effects ; Cell Adhesion/immunology ; Central Nervous System/immunology ; Central Nervous System/pathology ; Disease Models, Animal ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/immunology ; Female ; Humans ; Integrin alpha4/antagonists & inhibitors ; Integrin alpha4/metabolism ; Male ; Mice, Transgenic ; Microvessels/drug effects ; Microvessels/immunology ; Middle Aged ; Natalizumab/pharmacology ; Natalizumab/therapeutic use ; Susac Syndrome/blood ; Susac Syndrome/drug therapy ; Young Adult
Czasopismo naukowe
Tytuł :
Persistence of a T Cell Infiltrate in Human Ganglia Years After Herpes Zoster and During Post-herpetic Neuralgia.
Autorzy :
Sutherland JP; Emergency Department, Westmead Hospital, The University of Sydney, Sydney, NSW, Australia.
Steain M; Discipline of Infectious Diseases and Immunology, The University of Sydney, Sydney, NSW, Australia.
Buckland ME; Department of Neuropathology, Royal Prince Alfred Hospital, The University of Sydney, Sydney, NSW, Australia.
Rodriguez M; Department of Pathology, The University of Sydney, Sydney, NSW, Australia.
Cunningham AL; Centre for Virus Research, Westmead Institute for Medical Research, Westmead, NSW, Australia.
Slobedman B; Discipline of Infectious Diseases and Immunology, The University of Sydney, Sydney, NSW, Australia.
Abendroth A; Discipline of Infectious Diseases and Immunology, The University of Sydney, Sydney, NSW, Australia.
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Źródło :
Frontiers in microbiology [Front Microbiol] 2019 Sep 11; Vol. 10, pp. 2117. Date of Electronic Publication: 2019 Sep 11 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Correction to: Chronic traumatic encephalopathy in two former Australian National Rugby League players.
Autorzy :
Buckland ME; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia. michael.buckland@sydney.edu.au.; Discipline of Pathology, School of Medical Sciences, Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia. michael.buckland@sydney.edu.au.
Sy J; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.
Szentmariay I; Forensic and Analytical Science Service, Lidcombe, NSW, 2141, Australia.
Kullen A; Forensic and Analytical Science Service, Lidcombe, NSW, 2141, Australia.
Lee M; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.
Harding A; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.
Halliday G; Central Clinical School, Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia.
Suter CM; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.; Faculty of Medicine, University of New South Wales, Kensington, NSW, 2052, Australia.
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Źródło :
Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Jul 29; Vol. 7 (1), pp. 122. Date of Electronic Publication: 2019 Jul 29.
Typ publikacji :
Published Erratum
Tytuł :
Chronic traumatic encephalopathy in two former Australian National Rugby League players.
Autorzy :
Buckland ME; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia. michael.buckland@sydney.edu.au.; Discipline of Pathology, School of Medical Sciences, Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia. michael.buckland@sydney.edu.au.
Sy J; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.
Szentmariay I; Forensic and Analytical Science Service, Lidcombe, NSW, 2141, Australia.
Kullen A; Forensic and Analytical Science Service, Lidcombe, NSW, 2141, Australia.
Lee M; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.
Harding A; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.
Halliday G; Central Clinical School, Brain & Mind Centre, University of Sydney, Camperdown, NSW, 2006, Australia.
Suter CM; Department of Neuropathology, Royal Prince Alfred Hospital, 94 Mallet St, Camperdown, NSW, 2050, Australia.; Faculty of Medicine, University of New South Wales, Kensington, NSW, 2052, Australia.
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Źródło :
Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Jun 27; Vol. 7 (1), pp. 97. Date of Electronic Publication: 2019 Jun 27.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Chronic Traumatic Encephalopathy/*pathology
Football/*injuries
Australia ; Chronic Traumatic Encephalopathy/diagnosis ; Chronic Traumatic Encephalopathy/psychology ; Football/psychology ; Football/trends ; Humans ; Male ; Middle Aged
Raport
Tytuł :
Extracellular Vesicles Released by Glioblastoma Cells Stimulate Normal Astrocytes to Acquire a Tumor-Supportive Phenotype Via p53 and MYC Signaling Pathways.
Autorzy :
Hallal S; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, Level 7, 94 Mallett St, Camperdown, NSW, 2050, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Mallawaaratchy DM; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, Level 7, 94 Mallett St, Camperdown, NSW, 2050, Australia.
Wei H; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, Level 7, 94 Mallett St, Camperdown, NSW, 2050, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Ebrahimkhani S; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, Level 7, 94 Mallett St, Camperdown, NSW, 2050, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Stringer BW; Brain Cancer Research Unit, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Day BW; Brain Cancer Research Unit, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Boyd AW; Brain Cancer Research Unit, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Guillemin GJ; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Buckland ME; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, Level 7, 94 Mallett St, Camperdown, NSW, 2050, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Kaufman KL; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, Level 7, 94 Mallett St, Camperdown, NSW, 2050, Australia. .; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia. .; School of Life and Environmental Science, The University of Sydney, Sydney, NSW, Australia. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2019 Jun; Vol. 56 (6), pp. 4566-4581. Date of Electronic Publication: 2018 Oct 23.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Astrocytes/*metabolism
Brain Neoplasms/*metabolism
Extracellular Vesicles/*metabolism
Glioblastoma/*metabolism
Proto-Oncogene Proteins c-myc/*metabolism
Tumor Suppressor Protein p53/*metabolism
Aged ; Cell Differentiation ; Cell Line, Tumor ; Cellular Senescence ; Extracellular Vesicles/ultrastructure ; Gelatin/metabolism ; Humans ; Male ; Middle Aged ; Nanoparticles/ultrastructure ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Particle Size ; Phenotype ; Podosomes/metabolism ; Protein Isoforms/metabolism ; Proteolysis ; Proteome/metabolism
Czasopismo naukowe
Tytuł :
The emerging clinical potential of circulating extracellular vesicles for non-invasive glioma diagnosis and disease monitoring.
Autorzy :
Hallal S; Brainstorm Brain Cancer Research, Brain Tumour Research Laboratories, Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.; Discipline of Pathology, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.
Ebrahimkhani S; Discipline of Pathology, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Camperdown, NSW, Australia.
Shivalingam B; Department of Neurosurgery, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.
Graeber MB; Brain Tumour Research Laboratories, Brain and Mind Centre, Charles Perkins Centre, Bosch Institute and School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.
Kaufman KL; Brainstorm Brain Cancer Research, Brain Tumour Research Laboratories, Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.; Discipline of Pathology, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.; Department of Neurosurgery, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.
Buckland ME; Brainstorm Brain Cancer Research, Brain Tumour Research Laboratories, Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia. michael.buckland@sydney.edu.au.; Discipline of Pathology, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia. michael.buckland@sydney.edu.au.; Department of Neuropathology, Royal Prince Alfred Hospital, Brain and Mind Centre, Camperdown, NSW, Australia. michael.buckland@sydney.edu.au.
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Źródło :
Brain tumor pathology [Brain Tumor Pathol] 2019 Apr; Vol. 36 (2), pp. 29-39. Date of Electronic Publication: 2019 Mar 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biomarkers, Tumor/*blood
Extracellular Vesicles/*metabolism
Glioma/*pathology
Adult ; Biomarkers, Tumor/metabolism ; Biopsy ; Blood-Brain Barrier/metabolism ; Brain Neoplasms/pathology ; Disease Progression ; Extracellular Vesicles/physiology ; Glioblastoma/blood ; Glioblastoma/diagnosis ; Glioblastoma/pathology ; Glioma/blood ; Glioma/diagnosis ; Humans ; Liquid Biopsy/methods ; Liquid Biopsy/trends ; Neoplasm Recurrence, Local/pathology
Czasopismo naukowe
Tytuł :
Extracellular Vesicles from Neurosurgical Aspirates Identifies Chaperonin Containing TCP1 Subunit 6A as a Potential Glioblastoma Biomarker with Prognostic Significance.
Autorzy :
Hallal S; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia.; Sydney Medical School, University of Sydney, NSW, Australia.
Russell BP; Sydney Medical School, University of Sydney, NSW, Australia.
Wei H; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Lee MYT; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Toon CW; Sydney Medical School, University of Sydney, NSW, Australia.
Sy J; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Shivalingam B; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia.; Department of Neurosurgery, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.
Buckland ME; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia.; Sydney Medical School, University of Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Kaufman KL; Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia.; Department of Neuropathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.; School of Life and Environmental Science, University of Sydney, NSW, Australia.
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Źródło :
Proteomics [Proteomics] 2019 Jan; Vol. 19 (1-2), pp. e1800157.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Brain Neoplasms/*metabolism
Brain Neoplasms/*pathology
Chaperonin Containing TCP-1/*metabolism
Extracellular Vesicles/*metabolism
Glioblastoma/*metabolism
Glioblastoma/*pathology
Chaperonin Containing TCP-1/chemistry ; Chromatography, Liquid ; Glioma/metabolism ; Glioma/pathology ; Humans ; Prognosis ; Proteomics ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia mimicking systemic lupus erythematosus cerebral vasculitis.
Autorzy :
Lubomski M; Department of Neurology, Concord Repatriation General Hospital, Hospital Road, Concord, Sydney, NSW 2139, Australia; The University of Notre Dame Australia, School of Medicine, 160 Oxford St, Darlinghurst, NSW 2010, Sydney, Australia. Electronic address: .
Buckland ME; Department of Neuropathology, Royal Prince Alfred Hospital, Discipline of Pathology, University of Sydney, Level 7, BMC M02F, 94 Mallett Street, Camperdown, Sydney, NSW, 2050, Australia. Electronic address: michael.buckland@sydney.edu.au.
Sy J; Department of Neuropathology, Royal Prince Alfred Hospital, Level 7, BMC M02F, 94 Mallett Street, Camperdown, NSW 2050, Australia. Electronic address: .
Wei H; Department of Neuropathology, Royal Prince Alfred Hospital, Discipline of Pathology, University of Sydney, Level 7, BMC M02F, 94 Mallett Street, Camperdown, Sydney, NSW, 2050, Australia. Electronic address: .
Tan IYL; Radiology Department, Concord Repatriation General Hospital, Hospital Road, Concord, NSW 2139, Australia.
Kane B; Department of Rheumatology, Concord Repatriation General Hospital, Hospital Road, Concord, NSW 2139, Australia. Electronic address: .
Spring PJ; Department of Neurology, Concord Repatriation General Hospital, Hospital Road, Concord, NSW 2139, Australia. Electronic address: .
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Źródło :
Journal of the neurological sciences [J Neurol Sci] 2018 Dec 15; Vol. 395, pp. 25-28. Date of Electronic Publication: 2018 Sep 22.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Brain/*diagnostic imaging
Brain/*pathology
Leukoencephalopathies/*diagnosis
Leukoencephalopathies/*pathology
Diagnosis, Differential ; Fatal Outcome ; Humans ; Leukoencephalopathies/therapy ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/pathology ; Male ; Middle Aged ; Neuroglia/pathology ; Neurons/pathology ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/genetics ; Vasculitis, Central Nervous System/diagnosis ; Vasculitis, Central Nervous System/pathology
Raport
Tytuł :
Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis.
Autorzy :
Ebrahimkhani S; 1Department of Neuropathology, Brainstorm Brain Cancer Research, Royal Prince Alfred Hospital, Camperdown, NSW Australia.; 2Sydney Medical School, University of Sydney, Sydney, NSW Australia.
Vafaee F; 3School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW Australia.
Hallal S; 2Sydney Medical School, University of Sydney, Sydney, NSW Australia.
Wei H; 1Department of Neuropathology, Brainstorm Brain Cancer Research, Royal Prince Alfred Hospital, Camperdown, NSW Australia.
Lee MYT; 1Department of Neuropathology, Brainstorm Brain Cancer Research, Royal Prince Alfred Hospital, Camperdown, NSW Australia.
Young PE; 4Division of Molecular Structural and Computational Biology, Victor Chang Cardiac Research Institute, Sydney, NSW Australia.
Satgunaseelan L; 1Department of Neuropathology, Brainstorm Brain Cancer Research, Royal Prince Alfred Hospital, Camperdown, NSW Australia.; 5Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW Australia.
Beadnall H; 6Department of Neurology, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW Australia.
Barnett MH; 6Department of Neurology, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW Australia.
Shivalingam B; 7Department of Neurosurgery, Chris O'Brien Lifehouse, Sydney, NSW Australia.; 8Department of Neurosurgery, Royal Prince Alfred Hospital, Sydney, NSW Australia.
Suter CM; 4Division of Molecular Structural and Computational Biology, Victor Chang Cardiac Research Institute, Sydney, NSW Australia.; 9Faculty of Medicine, University of New South Wales, Sydney, NSW Australia.
Buckland ME; 1Department of Neuropathology, Brainstorm Brain Cancer Research, Royal Prince Alfred Hospital, Camperdown, NSW Australia.; 2Sydney Medical School, University of Sydney, Sydney, NSW Australia.
Kaufman KL; 1Department of Neuropathology, Brainstorm Brain Cancer Research, Royal Prince Alfred Hospital, Camperdown, NSW Australia.; 10School of Life and Environmental Sciences, University of Sydney, Sydney, NSW Australia.
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Źródło :
NPJ precision oncology [NPJ Precis Oncol] 2018 Dec 12; Vol. 2, pp. 28. Date of Electronic Publication: 2018 Dec 12 (Print Publication: 2018).
Typ publikacji :
Journal Article
Czasopismo naukowe

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