A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration.
Autorzy:
Na D; Department of Biomedical Engineering, Chung-Ang University, Seoul, Republic of Korea. Lim DH; College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.; School of Systems Biomedical Science, Soongsil University, Seoul, Republic of Korea. Hong JS; College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.; Center for Systems Biology, Massachusetts General Hospital, Boston, MA, USA. Lee HM; Department of Biomedical Engineering, Chung-Ang University, Seoul, Republic of Korea. Cho D; Department of Biomedical Engineering, Chung-Ang University, Seoul, Republic of Korea. Yu MS; Department of Biomedical Engineering, Chung-Ang University, Seoul, Republic of Korea. Shaker B; Department of Biomedical Engineering, Chung-Ang University, Seoul, Republic of Korea. Ren J; Department of Biomedical Engineering, Chung-Ang University, Seoul, Republic of Korea. Lee B; College of Life Sciences, Sejong University, Seoul, Republic of Korea. Song JG; College of Life Sciences, Sejong University, Seoul, Republic of Korea. Oh Y; Korea Institute of Science and Technology, Seoul, Republic of Korea. Lee K; Korea Institute of Science and Technology, Seoul, Republic of Korea. Oh KS; Information-based Drug Research Center, Korea Research Institute of Chemical Technology, Deajeon, Republic of Korea. Lee MY; Information-based Drug Research Center, Korea Research Institute of Chemical Technology, Deajeon, Republic of Korea. Choi MS; College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea. Choi HS; College of Life Sciences, Sejong University, Seoul, Republic of Korea. Kim YH; College of Life Sciences, Sejong University, Seoul, Republic of Korea. BuiJM; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada. Lee K; Department of Life Science, Chung-Ang University, Seoul, Republic of Korea. Kim HW; College of Life Sciences, Sejong University, Seoul, Republic of Korea. Lee YS; College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea. Gsponer J; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
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Źródło:
Molecular systems biology [Mol Syst Biol] 2023 Dec 06; Vol. 19 (12), pp. e11801. Date of Electronic Publication: 2023 Nov 20.
Comparison of Biomolecular Condensate Localization and Protein Phase Separation Predictors.
Autorzy:
Kuechler ER; Michael Smith Laboratories, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Huang A; Michael Smith Laboratories, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. BuiJM; Michael Smith Laboratories, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Mayor T; Michael Smith Laboratories, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Gsponer J; Michael Smith Laboratories, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
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Źródło:
Biomolecules [Biomolecules] 2023 Mar 13; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 13.
Protein-Protein Interactions Mediated by Intrinsically Disordered Protein Regions Are Enriched in Missense Mutations.
Autorzy:
Wong ETC; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. So V; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Guron M; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Kuechler ER; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Malhis N; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. BuiJM; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Gsponer J; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
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Źródło:
Biomolecules [Biomolecules] 2020 Jul 24; Vol. 10 (8). Date of Electronic Publication: 2020 Jul 24.
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