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Wyszukujesz frazę ""C. Gu"" wg kryterium: Autor


Tytuł:
T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα.
Autorzy:
Shen Y; Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai, China.; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Li G; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Gu C; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Chen B; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Chen A; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Li H; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Gao B; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Liang C; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Wu J; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Yang T; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
Jin L; Ministry of Education Key Laboratory of Contemporary Anthropology, Fudan University, Shanghai, China.
Su Y; R&D Department of Genetic Engineering, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd., Shanghai, China.
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Źródło:
PloS one [PLoS One] 2017 May 19; Vol. 12 (5), pp. e0177891. Date of Electronic Publication: 2017 May 19 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal/*pharmacology
Apoptosis/*drug effects
Cell Membrane/*metabolism
Receptors, IgG/*metabolism
Receptors, Tumor Necrosis Factor, Type II/*metabolism
Recombinant Fusion Proteins/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Antibody-Dependent Cell Cytotoxicity ; Cells, Cultured ; China ; Immunosuppressive Agents/pharmacology ; Mice ; Protein Binding ; Receptors, IgG/genetics ; Receptors, Tumor Necrosis Factor, Type II/genetics ; Recombinant Fusion Proteins/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł:
Sirtuin 1 Activator SRT1720 Protects Against Lung Injury via Reduction of Type II Alveolar Epithelial Cells Apoptosis in Emphysema.
Autorzy:
Gu C; a Department of Respiratory Medicine , Zhejiang Provincial People's Hospital , Hangzhou , Zhejiang , P.R. China.
Li Y
Xu WL
Yan JP
Xia YJ
Ma YY
Chen C
Wang HJ
Tao HQ
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Źródło:
COPD [COPD] 2015 Aug; Vol. 12 (4), pp. 444-52.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alveolar Epithelial Cells/*drug effects
Apoptosis/*drug effects
Enzyme Activators/*therapeutic use
Heterocyclic Compounds, 4 or More Rings/*therapeutic use
Lung Injury/*prevention & control
Pulmonary Emphysema/*drug therapy
Alveolar Epithelial Cells/physiology ; Animals ; Biomarkers/metabolism ; Blotting, Western ; Enzyme Activators/pharmacology ; Heterocyclic Compounds, 4 or More Rings/pharmacology ; Immunohistochemistry ; In Situ Nick-End Labeling ; Lung Injury/etiology ; Lung Injury/metabolism ; Male ; Pulmonary Emphysema/complications ; Pulmonary Emphysema/metabolism ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Real-Time Polymerase Chain Reaction ; Treatment Outcome
Czasopismo naukowe
Tytuł:
N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain.
Autorzy:
Chen S; Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Ren Q
Zhang J
Ye Y
Zhang Z
Xu Y
Guo M
Ji H
Xu C
Gu C
Gao W
Huang S
Chen L
Pokaż więcej
Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2014 Oct; Vol. 40 (6), pp. 759-77.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcysteine/*pharmacology
Apoptosis/*drug effects
Brain/*drug effects
Cadmium/*toxicity
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Animals ; Brain/metabolism ; Brain/ultrastructure ; Cadmium/blood ; Male ; Mice ; Mice, Inbred ICR ; Neurons/metabolism ; Neurons/ultrastructure ; Oxidative Stress/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage.
Autorzy:
Chen J; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Wang L
Wu C
Hu Q
Gu C
Yan F
Li J
Yan W
Chen G
Pokaż więcej
Źródło:
Journal of pineal research [J Pineal Res] 2014 Jan; Vol. 56 (1), pp. 12-9. Date of Electronic Publication: 2013 Aug 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Autophagy/*drug effects
Melatonin/*pharmacology
Melatonin/*therapeutic use
Mitochondria/*drug effects
Subarachnoid Hemorrhage/*drug therapy
Analysis of Variance ; Animals ; Brain Injuries/drug therapy ; Cytochromes c/metabolism ; In Situ Nick-End Labeling ; Male ; Rats ; Rats, Sprague-Dawley ; Subarachnoid Hemorrhage/pathology ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
A trigger model of apoptosis induced by tumor necrosis factor signaling.
Autorzy:
Gu C; Zhou Pei-Yuan Center for Applied Mathematics, Tsinghua University, Beijing, China.
Zhang J
Chen Y
Lei J
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Źródło:
BMC systems biology [BMC Syst Biol] 2011 Jun 20; Vol. 5 Suppl 1, pp. S13. Date of Electronic Publication: 2011 Jun 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/drug effects
Models, Biological*
Signal Transduction*/drug effects
Tumor Necrosis Factor-alpha/*metabolism
Caspase 3/metabolism ; Caspase 8/metabolism ; Enzyme Activation/drug effects ; Extracellular Space/drug effects ; Extracellular Space/metabolism ; Kinetics ; TNF-Related Apoptosis-Inducing Ligand/pharmacology
Czasopismo naukowe
Tytuł:
Expression of BIRC7 protein and mRNA in non-Hodgkin's lymphoma.
Autorzy:
Wu H; Department of Pathology, First Affiliated Hospital and Preclinical Medical School of Sun Yat-sen University, Guangzhou, 510080, China.
Ma Y
Zhu Y
Shen Y
Gu C
Ye Z
Lin H
Pokaż więcej
Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2006 Jun; Vol. 47 (6), pp. 1110-6.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Gene Expression Regulation, Neoplastic*
Adaptor Proteins, Signal Transducing/*biosynthesis
Inhibitor of Apoptosis Proteins/*biosynthesis
Lymphoma, Non-Hodgkin/*metabolism
Neoplasm Proteins/*biosynthesis
RNA, Neoplasm/*metabolism
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Child ; Female ; Humans ; Jurkat Cells ; K562 Cells ; Male ; Middle Aged ; Proto-Oncogene Proteins c-bcl-2/metabolism
Czasopismo naukowe

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