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Wyświetlanie 1-20 z 49
Tytuł:
Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation.
Autorzy:
Mandl M; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Drechsler M; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany; Academic Medical Center, Department of Pathology, Amsterdam University, Amsterdam, the Netherlands; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Jansen Y; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Neideck C; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Noels H; Institute for Molecular Cardiovascular Research, RWTH Aachen University Aachen, Aachen, Germany.
Faussner A; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Soehnlein O; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany; Academic Medical Center, Department of Pathology, Amsterdam University, Amsterdam, the Netherlands; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Weber C; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Döring Y; Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
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Źródło:
PloS one [PLoS One] 2015 Aug 07; Vol. 10 (8), pp. e0134176. Date of Electronic Publication: 2015 Aug 07 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammation/*pathology
Acute Disease ; Acute Lung Injury/pathology ; Animals ; Apolipoproteins E/deficiency ; Apolipoproteins E/metabolism ; Atherosclerosis/blood ; Atherosclerosis/pathology ; Bone Marrow/pathology ; Cell Count ; Chronic Disease ; Dendritic Cells/drug effects ; Dendritic Cells/immunology ; Diet, High-Fat ; Diphtheria Toxin/immunology ; Disease Models, Animal ; Leukocyte Common Antigens/metabolism ; Lipids/blood ; Lipopolysaccharides/administration & dosage ; Lipopolysaccharides/pharmacology ; Lung/drug effects ; Lung/pathology ; Mice, Inbred C57BL ; Mice, Transgenic ; Myeloid Cells/drug effects ; Myeloid Cells/pathology ; Spleen/pathology ; Transgenes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice.
Autorzy:
van den Berg SM; Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Seijkens TT; Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Kusters PJ; Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Zarzycka B; Department of Biochemistry, University of Maastricht, Maastricht, The Netherlands.
Beckers L; Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
den Toom M; Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Gijbels MJ; 1] Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands [2] Department of Pathology, Maastricht University, Maastricht, The Netherlands [3] Department of Molecular Genetics, Maastricht University, Maastricht,The Netherlands.
Chatzigeorgiou A; Department of Clinical Pathobiochemistry and Institute for Clinical Chemistry and Laboratory Medicine, Medical Faculty, Technische Universität Dresden, Dresden, Germany.
Weber C; 1] Department of Biochemistry, University of Maastricht, Maastricht, The Netherlands [2] Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian's University, Munich, Germany.
de Winther MP; Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Chavakis T; Department of Clinical Pathobiochemistry and Institute for Clinical Chemistry and Laboratory Medicine, Medical Faculty, Technische Universität Dresden, Dresden, Germany.
Nicolaes GA; Department of Biochemistry, University of Maastricht, Maastricht, The Netherlands.
Lutgens E; 1] Department of Medical Biochemistry, Subdivision of Experimental Vascular Biology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands [2] Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian's University, Munich, Germany.
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2015 May; Vol. 39 (5), pp. 782-90. Date of Electronic Publication: 2014 Nov 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adipose Tissue/*metabolism
Aniline Compounds/*pharmacology
CD40 Antigens/*antagonists & inhibitors
CD8-Positive T-Lymphocytes/*metabolism
Inflammation/*metabolism
Obesity/*complications
Propiophenones/*pharmacology
Signal Transduction/*drug effects
TNF Receptor-Associated Factor 6/*antagonists & inhibitors
Animals ; Cells, Cultured ; Diabetes Mellitus, Type 2/metabolism ; Diet, High-Fat ; Flow Cytometry ; Insulin Resistance ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/etiology ; Obesity/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models.
Autorzy:
Weber C; Institute for Molecular Cardiovascular Research, RWTH Aachen University, 52074 Aachen, Germany. />Zernecke A
Libby P
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Źródło:
Nature reviews. Immunology [Nat Rev Immunol] 2008 Oct; Vol. 8 (10), pp. 802-15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Atherosclerosis/*immunology
Atherosclerosis/*physiopathology
Inflammation/*immunology
Animals ; Atherosclerosis/metabolism ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Granulocytes/immunology ; Granulocytes/metabolism ; Humans ; Inflammation/metabolism ; Leukocytes/immunology ; Leukocytes/metabolism ; Macrophages/immunology ; Macrophages/metabolism ; Mast Cells/immunology ; Mast Cells/metabolism ; Mice ; Monocytes/immunology ; Monocytes/metabolism ; Stem Cells/immunology ; Stem Cells/physiology ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment.
Autorzy:
Bernhagen J; Department of Biochemistry and Molecular Cell Biology, Institute of Biochemistry, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, D-52074 Aachen, Germany.
Krohn R
Lue H
Gregory JL
Zernecke A
Koenen RR
Dewor M
Georgiev I
Schober A
Leng L
Kooistra T
Fingerle-Rowson G
Ghezzi P
Kleemann R
McColl SR
Bucala R
Hickey MJ
Weber C
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Źródło:
Nature medicine [Nat Med] 2007 May; Vol. 13 (5), pp. 587-96. Date of Electronic Publication: 2007 Apr 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis/*physiopathology
Endothelium, Vascular/*physiology
Inflammation/*physiopathology
Macrophage Migration-Inhibitory Factors/*physiology
Receptors, CXCR4/*physiology
Receptors, Interleukin-8B/*physiology
Aorta ; Chemotaxis ; Humans ; Leukocytes/physiology ; Ligands ; Macrophage Migration-Inhibitory Factors/pharmacology ; Monocytes/physiology ; T-Lymphocytes/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Chemokines: inflammatory mediators of atherosclerosis.
Autorzy:
Liehn EA; Institute of Molecular Cardiovascular Research (IMCAR), University Hospital, RWTH Aachen, Germany. />Zernecke A
Postea O
Weber C
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2006 Oct-Dec; Vol. 112 (4-5), pp. 229-38.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Signal Transduction*
Atherosclerosis/*physiopathology
Chemokines/*immunology
Endothelium, Vascular/*physiopathology
Inflammation/*physiopathology
Receptors, Chemokine/*immunology
Atherosclerosis/immunology ; Atherosclerosis/pathology ; Chemokines/metabolism ; Chemotaxis, Leukocyte/immunology ; Endothelium, Vascular/injuries ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Humans ; Inflammation/immunology ; Inflammation/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 49

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