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Wyszukujesz frazę ""CA1 Region, Hippocampal"" wg kryterium: Temat


Tytuł :
Distinct place cell dynamics in CA1 and CA3 encode experience in new environments.
Autorzy :
Dong C; Department of Neurobiology and Institute for Neuroscience, University of Chicago, Chicago, IL, USA.
Madar AD; Department of Neurobiology and Institute for Neuroscience, University of Chicago, Chicago, IL, USA.
Sheffield MEJ; Department of Neurobiology and Institute for Neuroscience, University of Chicago, Chicago, IL, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 May 20; Vol. 12 (1), pp. 2977. Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CA1 Region, Hippocampal/*physiology
CA3 Region, Hippocampal/*physiology
Place Cells/*physiology
Space Perception/*physiology
Spatial Memory/*physiology
Animals ; Behavior Observation Techniques ; Behavior, Animal/physiology ; CA1 Region, Hippocampal/cytology ; CA1 Region, Hippocampal/diagnostic imaging ; CA3 Region, Hippocampal/cytology ; CA3 Region, Hippocampal/diagnostic imaging ; Craniotomy ; Intravital Microscopy/instrumentation ; Intravital Microscopy/methods ; Male ; Mice ; Microscopy, Confocal/instrumentation ; Microscopy, Confocal/methods ; Models, Animal ; Optical Imaging/instrumentation ; Optical Imaging/methods
Czasopismo naukowe
Tytuł :
Serine/Threonine Phosphatases in LTP: Two B or Not to Be the Protein Synthesis Blocker-Induced Impairment of Early Phase.
Autorzy :
Maltsev AV; Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, 117485 Moscow, Russia.
Bal NV; Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, 117485 Moscow, Russia.
Balaban PM; Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, 117485 Moscow, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 04; Vol. 22 (9). Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
CA1 Region, Hippocampal/*metabolism
CA3 Region, Hippocampal/*metabolism
Calcineurin/*genetics
Long-Term Potentiation/*genetics
Synaptic Potentials/*genetics
Animals ; Anisomycin/pharmacology ; CA1 Region, Hippocampal/cytology ; CA1 Region, Hippocampal/drug effects ; CA3 Region, Hippocampal/cytology ; CA3 Region, Hippocampal/drug effects ; Calcineurin/metabolism ; Calcineurin Inhibitors/pharmacology ; Cycloheximide/pharmacology ; Cyclosporine/pharmacology ; Dentate Gyrus/cytology ; Dentate Gyrus/drug effects ; Dentate Gyrus/metabolism ; Gene Expression Regulation ; Long-Term Potentiation/drug effects ; Male ; Microtomy ; Neuronal Plasticity/drug effects ; Neuronal Plasticity/genetics ; Nitric Oxide/chemistry ; Nitric Oxide/pharmacology ; Nitric Oxide Synthase Type I/genetics ; Nitric Oxide Synthase Type I/metabolism ; Protein Biosynthesis/drug effects ; Protein Biosynthesis/genetics ; Protein Synthesis Inhibitors/pharmacology ; Rats ; Rats, Wistar ; S-Nitroso-N-Acetylpenicillamine/chemistry ; S-Nitroso-N-Acetylpenicillamine/pharmacology ; Synaptic Potentials/drug effects ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
An in vivo explorative study to observe the protective effects of Puerariae flos extract on chronic ethanol exposure and withdrawal male mice.
Autorzy :
Jiang B; School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116024, China. Electronic address: .
Yang W; School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116024, China.
Xiu Z; School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116024, China.
Zhang L; School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116024, China.
Ren X; School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 116024, China.
Wang L; Radiology Department, the First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Chen L; Radiology Department, the Affiliated Third Hospital of Xiamen, Fujian University of Traditional Chinese Medicine, Xiamen, 361100, China.
Asakawa T; Research Base of Traditional Chinese Medicine Syndrome, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China; Department of Neurosurgery, Hamamatsu University School of Medicine, Handayama, Hamamatsu-city, Shizuoka, Japan. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 May; Vol. 137, pp. 111306. Date of Electronic Publication: 2021 Jan 30.
Typ publikacji :
Journal Article
MeSH Terms :
Pueraria*/chemistry
Alcoholism/*drug therapy
Anxiety/*prevention & control
CA1 Region, Hippocampal/*drug effects
Depression/*prevention & control
Drugs, Chinese Herbal/*pharmacology
Hypothalamo-Hypophyseal System/*drug effects
Substance Withdrawal Syndrome/*drug therapy
Adrenocorticotropic Hormone/blood ; Alcoholism/metabolism ; Alcoholism/pathology ; Alcoholism/psychology ; Animals ; Anxiety/metabolism ; Anxiety/pathology ; Anxiety/psychology ; Behavior, Animal/drug effects ; Brain-Derived Neurotrophic Factor/metabolism ; CA1 Region, Hippocampal/metabolism ; CA1 Region, Hippocampal/pathology ; Corticotropin-Releasing Hormone/blood ; Depression/metabolism ; Depression/pathology ; Depression/psychology ; Disease Models, Animal ; Drugs, Chinese Herbal/isolation & purification ; Hydrocortisone/blood ; Hypothalamo-Hypophyseal System/metabolism ; Hypothalamo-Hypophyseal System/pathology ; Male ; Mice ; Substance Withdrawal Syndrome/metabolism ; Substance Withdrawal Syndrome/pathology ; Substance Withdrawal Syndrome/psychology
Czasopismo naukowe
Tytuł :
Loss of HCN2 in Dorsal Hippocampus of Young Adult Mice Induces Specific Apoptosis of the CA1 Pyramidal Neuron Layer.
Autorzy :
Deutsch M; Research Center Jülich, Institute of Biological Information Processing, IBI-1, 52428 Jülich, Germany.; Department of Biology, University of California, San Diego, La Jolla, CA 92083, USA.
Stegmayr C; Research Center Jülich, Institute of Neuroscience and Medicine, INM-4, 52428 Jülich, Germany.
Balfanz S; Research Center Jülich, Institute of Biological Information Processing, IBI-1, 52428 Jülich, Germany.
Baumann A; Research Center Jülich, Institute of Biological Information Processing, IBI-1, 52428 Jülich, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 22; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*genetics
CA1 Region, Hippocampal/*metabolism
Hippocampus/*metabolism
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/*deficiency
Potassium Channels/*deficiency
Pyramidal Cells/*metabolism
Age Factors ; Animals ; CA1 Region, Hippocampal/pathology ; Gene Knockdown Techniques ; Hippocampus/pathology ; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/chemistry ; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/metabolism ; Immunohistochemistry ; Mice ; Potassium Channels/chemistry ; Potassium Channels/metabolism ; Protein Binding ; Protein Interaction Domains and Motifs ; Pyramidal Cells/pathology ; RNA Interference
Czasopismo naukowe
Tytuł :
Reciprocal repulsions instruct the precise assembly of parallel hippocampal networks.
Autorzy :
Pederick DT; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Lui JH; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Gingrich EC; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.; Neurosciences Graduate Program, Stanford University, Stanford, CA, USA.
Xu C; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Wagner MJ; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Liu Y; F.M. Kirby Neurobiology Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
He Z; F.M. Kirby Neurobiology Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Quake SR; Departments of Bioengineering and Applied Physics, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, Stanford, CA, USA.
Luo L; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA. .
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Źródło :
Science (New York, N.Y.) [Science] 2021 Jun 04; Vol. 372 (6546), pp. 1068-1073.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Axon Guidance*
Axons/*physiology
CA1 Region, Hippocampal/*physiology
Hippocampus/*physiology
Membrane Proteins/*metabolism
Nerve Tissue Proteins/*metabolism
Receptors, Peptide/*metabolism
Animals ; CA1 Region, Hippocampal/cytology ; Entorhinal Cortex/physiology ; Female ; Hippocampus/cytology ; Ligands ; Male ; Membrane Glycoproteins/metabolism ; Membrane Proteins/genetics ; Mice ; Nerve Tissue Proteins/genetics ; Neural Pathways ; Receptors, Peptide/genetics ; Transcriptome
Czasopismo naukowe
Tytuł :
Telencephalon-specific Alkbh1 conditional knockout mice display hippocampal atrophy and impaired learning.
Autorzy :
Kawarada L; Laboratory of Animal Resources, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Japan.; Department of Biological Sciences, School of Science, The University of Tokyo, Japan.
Fukaya M; Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Japan.
Saito R; Laboratory of Animal Resources, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Japan.
Kassai H; Laboratory of Animal Resources, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Japan.
Sakagami H; Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Japan.
Aiba A; Laboratory of Animal Resources, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Japan.; Department of Biological Sciences, School of Science, The University of Tokyo, Japan.
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Źródło :
FEBS letters [FEBS Lett] 2021 Jun; Vol. 595 (12), pp. 1671-1680. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Learning*
AlkB Homolog 1, Histone H2a Dioxygenase/*deficiency
CA1 Region, Hippocampal/*metabolism
Pyramidal Cells/*metabolism
AlkB Homolog 1, Histone H2a Dioxygenase/metabolism ; Animals ; Atrophy ; CA1 Region, Hippocampal/pathology ; Gene Knockout Techniques ; Mice ; Mice, Knockout ; Pyramidal Cells/pathology
Czasopismo naukowe
Tytuł :
Distinct functions of ventral CA1 and dorsal CA2 in social memory.
Autorzy :
Watarai A; Laboratory of Behavioral Neuroscience, Institute for Quantitative Biosciences (IQB), The University of Tokyo, Tokyo, Japan.
Tao K; Laboratory of Behavioral Neuroscience, Institute for Quantitative Biosciences (IQB), The University of Tokyo, Tokyo, Japan.
Wang MY; Laboratory of Behavioral Neuroscience, Institute for Quantitative Biosciences (IQB), The University of Tokyo, Tokyo, Japan.
Okuyama T; Laboratory of Behavioral Neuroscience, Institute for Quantitative Biosciences (IQB), The University of Tokyo, Tokyo, Japan; JST, PRESTO, Tokyo, Japan. Electronic address: .
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Źródło :
Current opinion in neurobiology [Curr Opin Neurobiol] 2021 Jun; Vol. 68, pp. 29-35. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
CA1 Region, Hippocampal*
Memory*
Animals ; Hippocampus ; Humans ; Neurons ; Optogenetics
Czasopismo naukowe
Tytuł :
Downregulation of lncRNA GAS5 Alleviates Hippocampal Neuronal Damage in Mice with Depression-Like Behaviors Via Modulation of MicroRNA-26a/EGR1 Axis.
Autorzy :
Wu Y; Department of Medical Psychology, The First Affiliated Hospital of Wannan Medical College, No. 2, Zheshan West Road, Wuhu 241001, Anhui, PR China. Electronic address: .
Rong W; Department of Clinical Medical Psychology, The Second People's Hospital of Wuhu, Wuhu 241001, Anhui, PR China. Electronic address: .
Jiang Q; Department of Medical Psychology, The First Affiliated Hospital of Wannan Medical College, No. 2, Zheshan West Road, Wuhu 241001, Anhui, PR China. Electronic address: .
Wang R; Department of Medical Psychology, The First Affiliated Hospital of Wannan Medical College, No. 2, Zheshan West Road, Wuhu 241001, Anhui, PR China. Electronic address: .
Huang H; Department of Medical Psychology, The First Affiliated Hospital of Wannan Medical College, No. 2, Zheshan West Road, Wuhu 241001, Anhui, PR China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Mar; Vol. 30 (3), pp. 105550. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Behavior, Animal*
CA1 Region, Hippocampal/*metabolism
Depression/*metabolism
Early Growth Response Protein 1/*metabolism
MicroRNAs/*metabolism
Neurons/*metabolism
RNA, Long Noncoding/*metabolism
Animals ; CA1 Region, Hippocampal/pathology ; CA1 Region, Hippocampal/physiopathology ; Depression/genetics ; Depression/pathology ; Depression/psychology ; Disease Models, Animal ; Down-Regulation ; Early Growth Response Protein 1/genetics ; HEK293 Cells ; Humans ; Male ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Morris Water Maze Test ; Neurons/pathology ; Phosphatidylinositol 3-Kinase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Long Noncoding/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Complex effects of eslicarbazepine on inhibitory micro networks in chronic experimental epilepsy.
Autorzy :
Schmidt S; Medical Faculty, Institute for Experimental Epileptology and Cognition Research, University of Bonn, Bonn, Germany.
Pothmann L; Medical Faculty, Institute for Experimental Epileptology and Cognition Research, University of Bonn, Bonn, Germany.
Müller-Komorowska D; Medical Faculty, Institute for Experimental Epileptology and Cognition Research, University of Bonn, Bonn, Germany.
Opitz T; Medical Faculty, Institute for Experimental Epileptology and Cognition Research, University of Bonn, Bonn, Germany.
Soares da Silva P; BIAL -Portela & Ca. SA, S. Mamede do Coronado, Portugal.; Unit of Pharmacology & Therapeutics, Department of Biomedicine, Faculty of Medicine, University of Porto, Porto, Portugal.; MedInUP - Center for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal.
Beck H; Medical Faculty, Institute for Experimental Epileptology and Cognition Research, University of Bonn, Bonn, Germany.
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Źródło :
Epilepsia [Epilepsia] 2021 Feb; Vol. 62 (2), pp. 542-556. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticonvulsants/*pharmacology
CA1 Region, Hippocampal/*drug effects
Dibenzazepines/*pharmacology
Epilepsy/*physiopathology
Interneurons/*drug effects
Neural Inhibition/*drug effects
Pyramidal Cells/*drug effects
Adamantane/analogs & derivatives ; Adamantane/pharmacology ; Animals ; CA1 Region, Hippocampal/metabolism ; CA1 Region, Hippocampal/physiopathology ; Calcium/metabolism ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Epilepsy/chemically induced ; Feedback, Physiological/drug effects ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/physiopathology ; Inhibitory Postsynaptic Potentials/drug effects ; Interneurons/metabolism ; Long-Term Potentiation ; Muscarinic Agonists/toxicity ; Neuronal Plasticity ; Neurons/drug effects ; Neurons/metabolism ; Pilocarpine/toxicity ; Rats ; Receptors, AMPA/antagonists & inhibitors ; Receptors, AMPA/metabolism
Czasopismo naukowe
Tytuł :
The metaplastic effects of cordycepin in hippocampal CA1 area of rats.
Autorzy :
Mai ZF; School of Life Science, South China Normal University, Guangzhou, 510631, China.
Cao ZP; School of Life Science, South China Normal University, Guangzhou, 510631, China.
Huang SY; School of Life Science, South China Normal University, Guangzhou, 510631, China.
Yan WW; School of Life Science, South China Normal University, Guangzhou, 510631, China.
Huang JN; School of Life Science, South China Normal University, Guangzhou, 510631, China.
Wu BY; MOE Key Laboratory of Laser Life Science, Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, 510631, China. Electronic address: .
Li CH; School of Life Science, South China Normal University, Guangzhou, 510631, China. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Apr 15; Vol. 897, pp. 173946. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine A1 Receptor Agonists/*pharmacology
CA1 Region, Hippocampal/*drug effects
Deoxyadenosines/*pharmacology
Neuronal Plasticity/*drug effects
Receptor, Adenosine A1/*drug effects
Action Potentials/drug effects ; Animals ; CA1 Region, Hippocampal/metabolism ; Long-Term Potentiation/drug effects ; Long-Term Synaptic Depression/drug effects ; Male ; Rats, Sprague-Dawley ; Receptor, Adenosine A1/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Human Somatostatin SST 4 Receptor Transgenic Mice: Construction and Brain Expression Pattern Characterization.
Autorzy :
Nemes B; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.; János Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.
Bölcskei K; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.; János Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.
Kecskés A; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.; János Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.
Kormos V; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.; János Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.
Gaszner B; Research Group for Mood Disorders, Department of Anatomy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.
Aczél T; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.; János Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.
Hegedüs D; Research Group for Mood Disorders, Department of Anatomy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.
Pintér E; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.; János Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.; PharmInVivo Ltd., H-7629 Pécs, Hungary.; Algonist Biotechnologies Gmbh, 1030 Wien, Austria.
Helyes Z; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.; János Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.; PharmInVivo Ltd., H-7629 Pécs, Hungary.; Algonist Biotechnologies Gmbh, 1030 Wien, Austria.
Sándor Z; Department of Pharmacology and Pharmacotherapy, University of Pécs Medical School & Centre for Neuroscience, H-7624 Pécs, Hungary.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 04; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
CA1 Region, Hippocampal/*metabolism
CA2 Region, Hippocampal/*metabolism
Neurons/*metabolism
Receptors, Somatostatin/*biosynthesis
Animals ; CA1 Region, Hippocampal/cytology ; CA2 Region, Hippocampal/cytology ; Humans ; Mice ; Mice, Transgenic ; Receptors, Somatostatin/genetics
Czasopismo naukowe
Tytuł :
Chronic Low Dose Neutron Exposure Results in Altered Neurotransmission Properties of the Hippocampus-Prefrontal Cortex Axis in Both Mice and Rats.
Autorzy :
Krishnan B; Mitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Natarajan C; Mitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Bourne KZ; Mitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Alikhani L; Department of Radiation Oncology, University of California, Irvine, CA 92697, USA.
Wang J; Department of Pathology, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD 20814, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), 6720A Rockledge Drive, Bethesda, MD 20817, USA.
Sowa A; Microscopy CoRE and Advances Bioimaging Center, Icahn School of Medicine at Mount Sinai, 1468 Madison Ave., New York, NY 10029, USA.
Groen K; Department of Pathology, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD 20814, USA.
Perry B; Department of Pathology, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD 20814, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), 6720A Rockledge Drive, Bethesda, MD 20817, USA.
Dickstein DL; Department of Pathology, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD 20814, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), 6720A Rockledge Drive, Bethesda, MD 20817, USA.
Baulch JE; Department of Radiation Oncology, University of California, Irvine, CA 92697, USA.
Limoli CL; Department of Radiation Oncology, University of California, Irvine, CA 92697, USA.
Britten RA; Department of Radiation Oncology, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 01; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article
MeSH Terms :
CA1 Region, Hippocampal/*radiation effects
Cosmic Radiation/*adverse effects
Neuronal Plasticity/*radiation effects
Neutrons/*adverse effects
Prefrontal Cortex/*radiation effects
Animals ; Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; CA1 Region, Hippocampal/metabolism ; Dendrites/radiation effects ; Disks Large Homolog 4 Protein/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Scaling of Network Excitability and Inhibition may Contribute to the Septotemporal Differentiation of Sharp Waves-Ripples in Rat Hippocampus In Vitro.
Autorzy :
Trompoukis G; Laboratory of Physiology, Department of Medicine, University of Patras, Rion, Greece.
Leontiadis LJ; Laboratory of Physiology, Department of Medicine, University of Patras, Rion, Greece.
Rigas P; Laboratory of Physiology, Department of Medicine, University of Patras, Rion, Greece.
Papatheodoropoulos C; Laboratory of Physiology, Department of Medicine, University of Patras, Rion, Greece. Electronic address: .
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Źródło :
Neuroscience [Neuroscience] 2021 Mar 15; Vol. 458, pp. 11-30. Date of Electronic Publication: 2021 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA1 Region, Hippocampal*/metabolism
Hippocampus*/metabolism
Action Potentials ; Animals ; Neurons/metabolism ; Rats ; Receptors, GABA-A/metabolism
Czasopismo naukowe
Tytuł :
Functional Dysregulations in CA1 Hippocampal Networks of a 3-Hit Mouse Model of Schizophrenia.
Autorzy :
Percelay S; UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Normandie Université, 14000 Caen, France.
Billard JM; UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Normandie Université, 14000 Caen, France.
Freret T; UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Normandie Université, 14000 Caen, France.
Andrieux A; Inserm U1216, CEA, Grenoble Institut Neurosciences, Université Grenoble Alpes, 38000 Grenoble, France.
Boulouard M; UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Normandie Université, 14000 Caen, France.
Bouet V; UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Normandie Université, 14000 Caen, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 05; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Long-Term Potentiation*
Synaptic Transmission*
Theta Rhythm*
CA1 Region, Hippocampal/*physiopathology
Schizophrenia/*physiopathology
Animals ; CA1 Region, Hippocampal/pathology ; Disease Models, Animal ; Humans ; Mice ; Mice, Mutant Strains ; Schizophrenia/genetics ; Schizophrenia/pathology
Czasopismo naukowe
Tytuł :
Muscarinic Receptors, from Synaptic Plasticity to its Role in Network Activity.
Autorzy :
Fernández de Sevilla D; Departamento de Anatomía, Histología y Neurociencia, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain. Electronic address: .
Núñez A; Departamento de Anatomía, Histología y Neurociencia, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain.
Buño W; Instituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid 28029, Spain.
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Źródło :
Neuroscience [Neuroscience] 2021 Feb 21; Vol. 456, pp. 60-70. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
CA1 Region, Hippocampal*/metabolism
Neuronal Plasticity*
Hippocampus/metabolism ; Long-Term Potentiation ; Pyramidal Cells/metabolism ; Receptors, Muscarinic ; Receptors, N-Methyl-D-Aspartate/metabolism ; Synapses/metabolism
Czasopismo naukowe
Tytuł :
HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data.
Autorzy :
Sáray S; Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.; Institute of Experimental Medicine, Budapest, Hungary.
Rössert CA; Blue Brain Project, École Polytechnique Fédérale de Lausanne, Geneva, Switzerland.
Appukuttan S; Paris-Saclay Institute of Neuroscience, Centre National de la Recherche Scientifique/Université Paris-Saclay, Gif-sur-Yvette, France.
Migliore R; Institute of Biophysics, National Research Council, Palermo, Italy.
Vitale P; Institute of Biophysics, National Research Council, Palermo, Italy.
Lupascu CA; Institute of Biophysics, National Research Council, Palermo, Italy.
Bologna LL; Institute of Biophysics, National Research Council, Palermo, Italy.
Van Geit W; Blue Brain Project, École Polytechnique Fédérale de Lausanne, Geneva, Switzerland.
Romani A; Blue Brain Project, École Polytechnique Fédérale de Lausanne, Geneva, Switzerland.
Davison AP; Paris-Saclay Institute of Neuroscience, Centre National de la Recherche Scientifique/Université Paris-Saclay, Gif-sur-Yvette, France.
Muller E; Blue Brain Project, École Polytechnique Fédérale de Lausanne, Geneva, Switzerland.; Department of Neurosciences, Faculty of Medicine, University of Montreal, Montreal, Canada.; CHU Sainte-Justine Research Center, Montreal, Canada.; Quebec Artificial Intelligence Institute (Mila), Montreal, Canada.
Freund TF; Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.; Institute of Experimental Medicine, Budapest, Hungary.
Káli S; Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.; Institute of Experimental Medicine, Budapest, Hungary.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 Jan 29; Vol. 17 (1), pp. e1008114. Date of Electronic Publication: 2021 Jan 29 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA1 Region, Hippocampal*/cytology
CA1 Region, Hippocampal*/physiology
Models, Neurological*
Software*
Electrophysiological Phenomena/*physiology
Electrophysiology/*methods
Animals ; Computational Biology ; Dendrites/physiology ; Pyramidal Cells/cytology ; Pyramidal Cells/physiology ; Rats
Czasopismo naukowe
Tytuł :
Cellular correlates of cortical thinning throughout the lifespan.
Autorzy :
Vidal-Pineiro D; Centre for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Pb. 1094 Blindern, 0317, Oslo, Norway.
Parker N; Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, M4G 1R8, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Shin J; The Hospital for Sick Children, University of Toronto, Toronto, ON, M5G 1X8, Canada.
French L; Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, M5T 1L8, Canada.
Grydeland H; Centre for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Pb. 1094 Blindern, 0317, Oslo, Norway.
Jackowski AP; Interdisciplinary Lab for Clinical Neurosciences (LiNC), University Federal of São Paulo, São Paulo, 04038-020, Brazil.; National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, 90035-003, Brazil.
Mowinckel AM; Centre for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Pb. 1094 Blindern, 0317, Oslo, Norway.
Patel Y; Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, M4G 1R8, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Pausova Z; The Hospital for Sick Children, University of Toronto, Toronto, ON, M5G 1X8, Canada.
Salum G; National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, 90035-003, Brazil.; Department of Psychiatry, Federal University of Rio Grande do Sul, Porto Alegre, 90035-003, Brazil.
Sørensen Ø; Centre for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Pb. 1094 Blindern, 0317, Oslo, Norway.
Walhovd KB; Centre for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Pb. 1094 Blindern, 0317, Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, 0450, Oslo, Norway.
Paus T; Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, M4G 1R8, Canada. .; Institute of Medical Science, University of Toronto, Toronto, ON, M5S 1A8, Canada. .; Departments of Psychology and Psychiatry, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada. .
Fjell AM; Centre for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Pb. 1094 Blindern, 0317, Oslo, Norway. .; Department of Radiology and Nuclear Medicine, Oslo University Hospital, 0450, Oslo, Norway. .
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Corporate Authors :
Alzheimer’s Disease Neuroimaging Initiative and the Australian Imaging Biomarkers and Lifestyle flagship study of ageing
Źródło :
Scientific reports [Sci Rep] 2020 Dec 11; Vol. 10 (1), pp. 21803. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease*/diagnostic imaging
Alzheimer Disease*/metabolism
CA1 Region, Hippocampal*/diagnostic imaging
CA1 Region, Hippocampal*/metabolism
Cerebral Cortex*/diagnostic imaging
Cerebral Cortex*/metabolism
Cerebral Cortical Thinning*/diagnostic imaging
Cerebral Cortical Thinning*/metabolism
Cognitive Dysfunction*/diagnostic imaging
Cognitive Dysfunction*/metabolism
Longevity*
Magnetic Resonance Imaging*
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Differential Emergence and Stability of Sensory and Temporal Representations in Context-Specific Hippocampal Sequences.
Autorzy :
Taxidis J; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Integrative Center for Learning and Memory, Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: .
Pnevmatikakis EA; Center for Computational Mathematics, Flatiron Institute, New York, NY, USA.
Dorian CC; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Mylavarapu AL; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Arora JS; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Samadian KD; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Hoffberg EA; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Golshani P; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Integrative Center for Learning and Memory, Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA; West Los Angeles Veteran Affairs Medical Center, Los Angeles, CA, USA; Intellectual and Developmental Disabilities Research Center, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Dec 09; Vol. 108 (5), pp. 984-998.e9. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cues*
Odorants*
CA1 Region, Hippocampal/*physiology
Memory, Short-Term/*physiology
Smell/*physiology
Action Potentials ; Animals ; CA1 Region, Hippocampal/chemistry ; CA1 Region, Hippocampal/cytology ; Male ; Memory, Short-Term/drug effects ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Transgenic ; Microscopy, Fluorescence, Multiphoton/methods ; Smell/drug effects ; Time Factors
Czasopismo naukowe
Tytuł :
Large-Scale 3D Two-Photon Imaging of Molecularly Identified CA1 Interneuron Dynamics in Behaving Mice.
Autorzy :
Geiller T; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Vancura B; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Terada S; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Troullinou E; Institute of Computer Science, Foundation for Research and Technology Hellas, Heraklion, Crete 70013, Greece; Department of Computer Science, University of Crete, Heraklion, Crete 70013, Greece.
Chavlis S; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Crete 70013, Greece.
Tsagkatakis G; Department of Computer Science, University of Crete, Heraklion, Crete 70013, Greece.
Tsakalides P; Institute of Computer Science, Foundation for Research and Technology Hellas, Heraklion, Crete 70013, Greece; Department of Computer Science, University of Crete, Heraklion, Crete 70013, Greece.
Ócsai K; Faculty of Information Technology, Pázmány Péter University, Budapest, Hungary.
Poirazi P; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Crete 70013, Greece.
Rózsa BJ; Faculty of Information Technology, Pázmány Péter University, Budapest, Hungary; Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Losonczy A; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA; The Kavli Institute for Brain Science, Columbia University, New York, NY, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Dec 09; Vol. 108 (5), pp. 968-983.e9. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CA1 Region, Hippocampal/*cytology
CA1 Region, Hippocampal/*diagnostic imaging
Imaging, Three-Dimensional/*methods
Interneurons/*ultrastructure
Microscopy, Fluorescence, Multiphoton/*methods
Animals ; CA1 Region, Hippocampal/chemistry ; Calcium/analysis ; Calcium/metabolism ; Female ; Interneurons/chemistry ; Male ; Mice ; Mice, Transgenic ; Microscopy, Confocal/methods
Czasopismo naukowe
Tytuł :
Subcircuits of Deep and Superficial CA1 Place Cells Support Efficient Spatial Coding across Heterogeneous Environments.
Autorzy :
Sharif F; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Tayebi B; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA.
Buzsáki G; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA; Center for Neural Science, New York University, New York, NY 10003, USA; Department of Neurology, Langone Medical Center, New York University, New York, NY 10016, USA.
Royer S; Center for Functional Connectomics, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea; Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea. Electronic address: .
Fernandez-Ruiz A; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2021 Jan 20; Vol. 109 (2), pp. 363-376.e6. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Environment Design*
CA1 Region, Hippocampal/*physiology
Nerve Net/*physiology
Place Cells/*physiology
Space Perception/*physiology
Animals ; CA1 Region, Hippocampal/cytology ; Electrodes, Implanted ; Male ; Maze Learning/physiology ; Mice ; Mice, Inbred C57BL ; Nerve Net/cytology ; Rats ; Rats, Long-Evans
Czasopismo naukowe

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