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Tytuł:
Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium.
Autorzy:
Nagaoka T; Division for Therapies Against Intractable Diseases, Center for Medical Science, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan. .
Katsuno T; Center for Anatomical, Pathological and Forensic Medical Researches, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Fujimura K; Division for Therapies Against Intractable Diseases, Center for Medical Science, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan.
Tsuchida K; Division for Therapies Against Intractable Diseases, Center for Medical Science, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan. .
Kishi M; Neuroscience Laboratory, Research Institute, Nozaki Tokushukai Hospital, 2-10-50 Tanigawa, Daito, Osaka, 574-0074, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Mar 08; Vol. 13 (1), pp. 3905. Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Neural Tube*/metabolism
Cadherins*/genetics
Cadherins*/metabolism
Mice ; Animals ; Cell Polarity/genetics ; Wnt Signaling Pathway/physiology ; Epithelium
Czasopismo naukowe
Tytuł:
Neonatal lethality of mouse A/J-7 consomic strain is caused by an insertion mutation in the Dchs1 gene.
Autorzy:
Miyasaka Y; Division of Experimental Animals, Graduate School of Medicine, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, 466-8550, Japan. .
Kobayashi T; Division of Experimental Animals, Graduate School of Medicine, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, 466-8550, Japan.
Gotoh N; Division of Experimental Animals, Graduate School of Medicine, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, 466-8550, Japan.
Kuga M; Division of Experimental Animals, Graduate School of Medicine, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, 466-8550, Japan.
Kobayashi M; Department of Nutritional Sciences, Nagoya University of Arts and Sciences, 57 Takenoyama, Iwasaki-Cho, Nisshin, Aichi, 470-0196, Japan.
Horio F; Department of Life Studies and Environmental Science, Nagoya Women's University, 3-40 Shioji-Cho, Mizuho-Ku, Nagoya, Aichi, 467-8610, Japan.
Hashimoto K; Faculty of Medical Sciences, Shubun University, 6 Nikko-Cho, Ichinomiya, Aichi, 491-0938, Japan.
Kawabe T; Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, 1-1-20 Dikou-Minami, Higashi-Ku, Nagoya, Aichi, 461-8673, Japan.
Ohno T; Division of Experimental Animals, Graduate School of Medicine, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, 466-8550, Japan. .
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2023 Mar; Vol. 34 (1), pp. 32-43. Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosomes*
Cadherins*/genetics
Cadherins*/metabolism
Mice ; Animals ; Mutagenesis, Insertional ; Alleles ; Mutation
Czasopismo naukowe
Tytuł:
Suppression of P-cadherin expression as a key regulatory element for embryonic stem cell stemness.
Autorzy:
Takeda Y; Department of Biomedical Sciences, Graduate School of Science and Technology, Kwansei Gakuin University.
Matsuguchi S; Department of Biomedical Sciences, Graduate School of Science and Technology, Kwansei Gakuin University.
Nozaki S; Department of Biomedical Sciences, Graduate School of Science and Technology, Kwansei Gakuin University.
Mihara T; Department of Biomedical Sciences, Graduate School of Science and Technology, Kwansei Gakuin University.
Abe J; Department of Biomedical Sciences, Graduate School of Science and Technology, Kwansei Gakuin University.
Hirai Y; Department of Biomedical Sciences, Graduate School of Science and Technology, Kwansei Gakuin University.
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Źródło:
Cell structure and function [Cell Struct Funct] 2023 Feb 08; Vol. 48 (1), pp. 49-57. Date of Electronic Publication: 2022 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Cadherins*/genetics
Cadherins*/metabolism
Embryonic Stem Cells*/metabolism
Cell Differentiation ; Cell Communication ; SNARE Proteins/metabolism ; SNARE Proteins/pharmacology
Czasopismo naukowe
Tytuł:
Transient interactions drive the lateral clustering of cadherin-23 on membrane.
Autorzy:
Srinivas CS; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Singaraju GS; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Kaur V; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Das S; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Ghosh SK; Department of Physical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Sagar A; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Kumar A; Department of Physical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.; Centre for Protein Science Design and Engineering, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Bhatia T; Department of Physical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India.
Rakshit S; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India. .; Centre for Protein Science Design and Engineering, Indian Institute of Science Education and Research Mohali, Mohali, Punjab, India. .
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Źródło:
Communications biology [Commun Biol] 2023 Mar 18; Vol. 6 (1), pp. 293. Date of Electronic Publication: 2023 Mar 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins*/metabolism
Protein Binding ; Cell Adhesion
Czasopismo naukowe
Tytuł:
Amphiphilic peptide-tagged N-cadherin forms radial glial-like fibers that enhance neuronal migration in injured brain and promote sensorimotor recovery.
Autorzy:
Ohno Y; Department of Developmental and Regenerative Neurobiology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan; Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan.
Nakajima C; Department of Developmental and Regenerative Neurobiology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan.
Ajioka I; Center for Brain Integration Research (CBIR), Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, 113-8510, Japan; Kanagawa Institute of Industrial Science and Technology (KISTEC), Kanagawa, 243-0435, Japan.
Muraoka T; Kanagawa Institute of Industrial Science and Technology (KISTEC), Kanagawa, 243-0435, Japan; Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan.
Yaguchi A; Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan.
Fujioka T; Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan.
Akimoto S; Center for Brain Integration Research (CBIR), Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, 113-8510, Japan; Kanagawa Institute of Industrial Science and Technology (KISTEC), Kanagawa, 243-0435, Japan.
Matsuo M; Department of Developmental and Regenerative Neurobiology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan.
Lotfy A; Biotechnology and Life Sciences Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, 62511, Egypt.
Nakamura S; Department of Developmental and Regenerative Neurobiology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan.
Herranz-Pérez V; Laboratory of Comparative Neurobiology, Cavanilles Institute, University of Valencia, CIBERNED, Valencia, 46980, Spain.
García-Verdugo JM; Laboratory of Comparative Neurobiology, Cavanilles Institute, University of Valencia, CIBERNED, Valencia, 46980, Spain.
Matsukawa N; Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan.
Kaneko N; Department of Developmental and Regenerative Neurobiology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan; Laboratory of Neuronal Regeneration, Graduate School of Brain Science, Doshisha University, Kyotanabe, Kyoto, 610-0394, Japan. Electronic address: .
Sawamoto K; Department of Developmental and Regenerative Neurobiology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan; Division of Neural Development and Regeneration, National Institute of Physiological Sciences, Okazaki, Aichi, 444-8585, Japan. Electronic address: .
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Źródło:
Biomaterials [Biomaterials] 2023 Mar; Vol. 294, pp. 122003. Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins*
Neural Stem Cells*
Animals ; Brain ; Neurons ; Peptides ; Mammals
Czasopismo naukowe
Tytuł:
E-cadherin-dependent coordinated epithelial rotation on a two-dimensional discoidal pattern.
Autorzy:
Luo S; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Furuya K; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Radiation Biology Center, Kyoto University, Kyoto, Japan.
Matsuda K; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Research Center for Dynamic Living Systems, Kyoto University, Kyoto, Japan.
Tsukasa Y; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Usui T; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Uemura T; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Research Center for Dynamic Living Systems, Kyoto University, Kyoto, Japan.
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Źródło:
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2023 Mar; Vol. 28 (3), pp. 175-187. Date of Electronic Publication: 2022 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Cadherins*/metabolism
Epithelial Cells*/metabolism
Animals ; Dogs ; Cell Adhesion ; Madin Darby Canine Kidney Cells ; Cell Movement
Czasopismo naukowe
Tytuł:
Soluble E-cadherin: A marker of genital epithelial disruption.
Autorzy:
Liu R; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Armstrong E; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Constable S; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Buchanan LB; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Mohammadi A; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Galiwango RM; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Huibner S; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Perry MC; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Prodger JL; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Coburn B; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.; Department of Medicine, University Health Network, Toronto, Ontario, Canada.
Kaul R; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.; Department of Medicine, University Health Network, Toronto, Ontario, Canada.
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Źródło:
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2023 Mar; Vol. 89 (3), pp. e13674. Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins*
HIV Infections*
Male ; Humans ; Female ; Interleukin-6 ; Canada ; Cervix Uteri
Czasopismo naukowe
Tytuł:
Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression.
Autorzy:
Chen J; Department of Physiology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Lin Y; Department of Physiology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Sun Z; Department of Physiology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA. .; Department of Physiology, College of Medicine, UT Cardiovascular Institute, University of Tennessee Health Science Center, 956 Court Avenue, Memphis, TN, 38163, USA. .
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Źródło:
Molecular medicine (Cambridge, Mass.) [Mol Med] 2023 Feb 21; Vol. 29 (1), pp. 24. Date of Electronic Publication: 2023 Feb 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Aortic Valve Disease*/genetics
MicroRNAs*/genetics
SOX9 Transcription Factor*/genetics
Cadherins*/genetics
Adult ; Humans ; Aortic Valve ; Cells, Cultured ; Osteogenesis/genetics ; Signal Transduction
SCR Disease Name:
Aortic Valve, Calcification of
Czasopismo naukowe
Tytuł:
Structure of the planar cell polarity cadherins Fat4 and Dachsous1.
Autorzy:
Medina E; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33602, USA.; Cancer Biology Ph.D Program, University of South Florida, Tampa, FL, 33602, USA.
Easa Y; School of Neurobiology, Biochemistry, and Biophysics, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Lester DK; Cancer Biology Ph.D Program, University of South Florida, Tampa, FL, 33602, USA.; Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33602, USA.; Molecular Medicine Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33602, USA.
Lau EK; Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33602, USA.; Molecular Medicine Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33602, USA.
Sprinzak D; School of Neurobiology, Biochemistry, and Biophysics, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.
Luca VC; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33602, USA. .; Molecular Medicine Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, 33602, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Feb 16; Vol. 14 (1), pp. 891. Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins*/chemistry
Cell Polarity*
Tumor Suppressor Proteins*/chemistry
Humans ; Cadherin Related Proteins/chemistry
Czasopismo naukowe
Tytuł:
CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.
Autorzy:
Jia Z; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China.; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.
Yang M; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China.; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.
Zhao Y; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China.; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.
Li X; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China.; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.
Yang C; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China.; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.
Qiao L; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China.; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.
Li H; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China.; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.
Du J; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China.; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China.; School of Medical Engineering, Xinxiang Medical University, Xinxiang, China.
Lin J; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China. .; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China. .; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China. .; School of Medical Engineering, Xinxiang Medical University, Xinxiang, China. .
Guan L; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, China. .; Henan Key Laboratory of Medical Tissue Regeneration, Xinxiang, China. .; Henan Joint International Research Laboratory of Stem Cell Medicine, Stem Cell and Biotherapy Engineering Research Center of Henan, Xinxiang, China. .
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Źródło:
Molecular biotechnology [Mol Biotechnol] 2023 Feb; Vol. 65 (2), pp. 252-262. Date of Electronic Publication: 2022 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
CRISPR-Cas Systems*
Cadherins*
Humans ; Cell Adhesion/genetics ; Gene Deletion ; HEK293 Cells ; Niemann-Pick C1 Protein
Czasopismo naukowe
Tytuł:
PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer.
Autorzy:
Elsharkawi SM; Department of Clinical and Chemical Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt. .
Elkaffash D; Department of Clinical and Chemical Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Moez P; Department of Clinical and Chemical Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
El-Etreby N; Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Sheta E; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Taleb RSZ; Department of Clinical and Chemical Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
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Źródło:
BMC cancer [BMC Cancer] 2023 Jan 25; Vol. 23 (1), pp. 89. Date of Electronic Publication: 2023 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Ovarian Epithelial*/genetics
DNA Methylation*
Ovarian Neoplasms*/genetics
Promoter Regions, Genetic*
Cadherins*/genetics
Female ; Humans ; Egypt ; Ovarian Cysts
Czasopismo naukowe
Tytuł:
E-cadherin in developing murine T cells controls spindle alignment and progression through β-selection.
Autorzy:
Charnley M; Optical Sciences Centre, School of Science, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia.; Immune Signalling Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Allam AH; Optical Sciences Centre, School of Science, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia.; Immune Signalling Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Newton LM; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.; Research Centre for Molecular Cancer Prevention, La Trobe University, Melbourne, Victoria 3086, Australia.
Humbert PO; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.; Research Centre for Molecular Cancer Prevention, La Trobe University, Melbourne, Victoria 3086, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Victoria 3010, Australia.; Department of Clinical Pathology, University of Melbourne, Melbourne, Victoria 3010, Australia.
Russell SM; Optical Sciences Centre, School of Science, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia.; Immune Signalling Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria 3010, Australia.
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Źródło:
Science advances [Sci Adv] 2023 Jan 18; Vol. 9 (3), pp. eade5348. Date of Electronic Publication: 2023 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Cadherins*/metabolism
T-Lymphocytes*/cytology
T-Lymphocytes*/metabolism
Animals ; Mice ; Cell Communication ; Receptors, Antigen, T-Cell, alpha-beta ; Thymus Gland ; Spindle Apparatus/metabolism
Czasopismo naukowe
Tytuł:
E-cadherin mediates apical membrane initiation site localisation during de novo polarisation of epithelial cavities.
Autorzy:
Liang X; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Weberling A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Hii CY; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Zernicka-Goetz M; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Buckley CE; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
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Źródło:
The EMBO journal [EMBO J] 2022 Dec 15; Vol. 41 (24), pp. e111021. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Polarity*
Cadherins*/genetics
Cadherins*/metabolism
Animals ; Mice ; Cell Membrane/metabolism ; Cell Adhesion ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
A pan-cancer analysis of the FAT1 in human tumors.
Autorzy:
Wang Z; The First Clinical Medical College of Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Lin K; Tongji University School of Medicine, Shanghai, 200090, China.
Xiao H; The First Clinical Medical College of Gannan Medical University, Ganzhou, 341000, Jiangxi, China. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 14; Vol. 12 (1), pp. 21598. Date of Electronic Publication: 2022 Dec 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins*/genetics
Cadherins*/metabolism
Neoplasms*/genetics
Neoplasms*/metabolism
Humans ; Mutation ; Prognosis ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
Loss of E-cadherin is causal to pathologic changes in chronic lung disease.
Autorzy:
Ghosh B; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Loube J; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Thapa S; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Ryan H; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Capodanno E; Johns Hopkins University, Baltimore, MD, USA.
Chen D; Johns Hopkins University, Baltimore, MD, USA.
Swaby C; Johns Hopkins University, Baltimore, MD, USA.
Chen S; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Pulmonary and Critical Care Medicine, Shanghai East Hospital, Tongji University, Shanghai, 200120, China.
Mahmud S; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Girgis M; Johns Hopkins University, Baltimore, MD, USA.
Nishida K; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Ying L; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Respiration, Children's Hospital of Chongqing Medical University, Chongqing, China.
Chengala PP; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Tieng E; Johns Hopkins University, Baltimore, MD, USA.
Burnim M; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Wally A; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Bhowmik D; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Zaykaner M; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Yeung-Luk B; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Mitzner W; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Biswal S; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Sidhaye VK; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. .; Department of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA. .
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Źródło:
Communications biology [Commun Biol] 2022 Oct 29; Vol. 5 (1), pp. 1149. Date of Electronic Publication: 2022 Oct 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cadherins*/genetics
Cadherins*/metabolism
Pulmonary Disease, Chronic Obstructive*/genetics
Pulmonary Disease, Chronic Obstructive*/metabolism
Animals ; Mice ; Epithelial Cells/metabolism ; Epithelium/metabolism ; Lung/pathology
Czasopismo naukowe
Tytuł:
Cadherin-mediated adhesion takes control.
Autorzy:
Herranz G; Program of Tissue and Organ Homeostasis, Centro de Biología Molecular 'Severo Ochoa', CSIC-UAM, Madrid, Spain.
Martín-Belmonte F; Program of Tissue and Organ Homeostasis, Centro de Biología Molecular 'Severo Ochoa', CSIC-UAM, Madrid, Spain.
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Źródło:
The EMBO journal [EMBO J] 2022 Dec 15; Vol. 41 (24), pp. e112662. Date of Electronic Publication: 2022 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins*/metabolism
Cell Polarity*
Cell Adhesion ; Cell Membrane/metabolism ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing.
Autorzy:
Kerschbamer E; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
Arnoldi M; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
Tripathi T; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
Pellegrini M; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
Maturi S; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
Erdin S; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
Salviato E; IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy.
Di Leva F; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
Sebestyén E; IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy.
Dassi E; Laboratory of RNA Regulatory Networks, Department of Cellular, Computational and Integrative Biology, (CIBIO), University of Trento, Trento, Italy.
Zarantonello G; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
Benelli M; Bioinformatics Unit, Hospital of Prato, Istituto Toscano Tumori, Prato, Italy.
Campos E; Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Canada.
Basson MA; Centre for Craniofacial and Regenerative Biology and MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.
Gusella JF; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA.
Gustincich S; Central RNA Laboratory, Istituto Italiano di Tecnologia (IIT), Genova, Italy.
Piazza S; Bioinformatic facility, Department of Cellular, Computational and Integrative Biology (CIBIO) University of Trento, Italy.
Demichelis F; Laboratory of Computational and Functional Oncology, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.
Talkowski ME; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA.
Ferrari F; IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy.; CNR Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', Pavia, Italy.
Biagioli M; NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, (CIBIO) University of Trento, Trento, Italy.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Dec 09; Vol. 50 (22), pp. 12809-12828.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Alternative Splicing*
Histones*/metabolism
Cadherins*/genetics
Chromatin ; Lysine/metabolism ; RNA/metabolism ; Humans ; Induced Pluripotent Stem Cells ; Neural Stem Cells ; Autism Spectrum Disorder/genetics
Czasopismo naukowe
Tytuł:
INT6/eIF3e represses E-cadherin expression through HIF2α in lung carcinoma A549 cells.
Autorzy:
Gotoh-Saito S; Department of Molecular Medical Research, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Sadato D; Department of Molecular Medical Research, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Shibasaki F; Department of Molecular Medical Research, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
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Źródło:
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2022 Dec; Vol. 27 (12), pp. 689-705. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Cadherins*/genetics
Carcinoma*
Eukaryotic Initiation Factor-3*
Basic Helix-Loop-Helix Transcription Factors*
Lung Neoplasms*
Humans ; A549 Cells ; Lung
Czasopismo naukowe
Tytuł:
FAT1 downregulation enhances stemness and cisplatin resistance in esophageal squamous cell carcinoma.
Autorzy:
Zhai Y; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China.; Department of Pathology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.
Shan C; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China.; Department of Pharmacology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.
Zhang H; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China.; Department of Pathology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.
Kong P; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China.; Department of Pathology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.
Zhang L; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China.; Department of Pathology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.
Wang Y; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China.; Department of Pathology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.
Hu X; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China. .; Department of Pharmacology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China. .
Cheng X; Key Laboratory of Cellular Physiology of the Ministry of Education, Shanxi Medical University, 56 Xin Jian Nan Road, Taiyuan, 030001, Shanxi, People's Republic of China. .; Department of Pathology, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China. .
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Źródło:
Molecular and cellular biochemistry [Mol Cell Biochem] 2022 Dec; Vol. 477 (12), pp. 2689-2702. Date of Electronic Publication: 2022 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Cadherins*/metabolism
Esophageal Neoplasms*/drug therapy
Esophageal Neoplasms*/genetics
Esophageal Neoplasms*/metabolism
Esophageal Squamous Cell Carcinoma*/drug therapy
Esophageal Squamous Cell Carcinoma*/genetics
Drug Resistance, Neoplasm*
Neoplastic Stem Cells*
Humans ; beta Catenin/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Cisplatin/pharmacology ; Down-Regulation ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Tytuł:
A computational modeling approach for predicting multicell spheroid patterns based on signaling-induced differential adhesion.
Autorzy:
Sivakumar N; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.
Warner HV; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.
Peirce SM; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.
Lazzara MJ; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2022 Nov 28; Vol. 18 (11), pp. e1010701. Date of Electronic Publication: 2022 Nov 28 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins*/metabolism
Signal Transduction*
Cell Adhesion/physiology ; Computer Simulation ; Cell Communication ; Embryonic Development
Czasopismo naukowe

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