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Tytuł :
Mechanism of REST/NRSF regulation of clustered protocadherin α genes.
Autorzy :
Tang Y; Center for Comparative Biomedicine, MOE Key Laboratory of Systems Biomedicine, State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Institute of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Jia Z; Center for Comparative Biomedicine, MOE Key Laboratory of Systems Biomedicine, State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Institute of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Xu H; Center for Comparative Biomedicine, MOE Key Laboratory of Systems Biomedicine, State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Institute of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Da LT; Center for Comparative Biomedicine, MOE Key Laboratory of Systems Biomedicine, State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Institute of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Wu Q; Center for Comparative Biomedicine, MOE Key Laboratory of Systems Biomedicine, State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Institute of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 May 07; Vol. 49 (8), pp. 4506-4521.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enhancer Elements, Genetic*
Promoter Regions, Genetic*
Zinc Fingers*
Cadherins/*metabolism
Gene Expression Regulation/*genetics
Repressor Proteins/*metabolism
Animals ; Cadherins/chemistry ; Cadherins/genetics ; Cell Line, Tumor ; Chromatin Immunoprecipitation Sequencing ; DNA Methylation ; Humans ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Molecular Dynamics Simulation ; Multigene Family ; Protein Binding ; Protein Domains ; RNA-Seq ; Repressor Proteins/chemistry ; Repressor Proteins/genetics
Czasopismo naukowe
Tytuł :
Cadherins in early neural development.
Autorzy :
Punovuori K; Helsinki Institute of Life Science, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland.; Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290, Helsinki, Finland.
Malaguti M; Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Little France Drive, Edinburgh, EH16 4UU, UK.
Lowell S; Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Little France Drive, Edinburgh, EH16 4UU, UK. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 May; Vol. 78 (9), pp. 4435-4450. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cadherins/*metabolism
Neural Crest/*metabolism
Animals ; Cadherins/chemistry ; Cadherins/classification ; Cell Adhesion ; Cell Differentiation ; Evolution, Molecular ; Humans ; Neural Crest/cytology ; Neural Crest/growth & development ; Neurogenesis ; Signal Transduction ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Salivary Duct Carcinoma With Rhabdoid Features-No or Aberrant Expression of E-cadherin and Genetic Changes in CDH1: Immunohistochemical and Genetic Analyses of 17 Cases.
Autorzy :
Kusafuka K; Department of Pathology, Shizuoka General Hospital, Shizuoka City.
Yamada H; Department of Tumor Pathology, Hamamatsu University School of Medicine.
Ishino K; Department of Tumor Pathology, Hamamatsu University School of Medicine.
Maeda M; Department of Diagnostic Pathology, Toyohashi Municipal Hospital, Toyohashi, Aichi Prefecture.
Yamanegi K; Department of Pathology, Hyogo Medical College, Nishinomiya, Hyogo Prefecture.
Baba S; Department of Diagnostic Pathology, Hamamatsu University School of Medicine Hospital, Hamamatsu, Shizuoka Prefecture.
Ohuchi T; Department of Diagnostic Pathology, Keiyukai Sapporo Hospital, Sapporo, Hokkaido Prefecture.
Inagaki H; Department of Pathology and Molecular Diagnostics, Nagoya City University, Nagoya, Aichi Prefecture.
Yamamoto H; Department of Surgical Pathology, Kyushu University, Fukuoka, Fukuoka Prefecture, Japan.
Iwasaki T; Department of Pathology, Shizuoka General Hospital, Shizuoka City.
Tsuchiya C; Department of Pathology, Shizuoka General Hospital, Shizuoka City.
Sugimura H; Department of Tumor Pathology, Hamamatsu University School of Medicine.
Suzuki M; Department of Pathology, Shizuoka General Hospital, Shizuoka City.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 Apr 01; Vol. 45 (4), pp. 439-449.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenoma, Pleomorphic*/chemistry
Adenoma, Pleomorphic*/genetics
Adenoma, Pleomorphic*/pathology
Antigens, CD*/analysis
Antigens, CD*/genetics
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/genetics
Cadherins*/analysis
Cadherins*/genetics
Carcinoma*/chemistry
Carcinoma*/genetics
Carcinoma*/pathology
Mutation*
Salivary Gland Neoplasms*/chemistry
Salivary Gland Neoplasms*/genetics
Salivary Gland Neoplasms*/pathology
Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/chemistry ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Carcinoma, Lobular/chemistry ; Carcinoma, Lobular/genetics ; Carcinoma, Lobular/pathology ; DNA Mutational Analysis ; Female ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Exploration of zebrafish larvae as an alternative whole-animal model for nephrotoxicity testing.
Autorzy :
Bauer B; Department of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
Liedtke D; Institute of Human Genetics, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
Jarzina S; Department of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
Stammler E; Department of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
Kreisel K; Department of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
Lalomia V; Department of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
Diefenbacher M; Chair of Biochemistry and Molecular Biology, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
Klopocki E; Institute of Human Genetics, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
Mally A; Department of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Jun 15; Vol. 344, pp. 69-81. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Zebrafish*
Cadherins/*metabolism
Toxicity Tests/*methods
Zebrafish Proteins/*metabolism
Animals ; Biomarkers/metabolism ; Cadherins/genetics ; Central Nervous System ; Gene Expression Regulation, Developmental/drug effects ; Kidney/drug effects ; Larva ; Zebrafish Proteins/genetics
Czasopismo naukowe
Tytuł :
Direct conversion of adult human fibroblasts into functional endothelial cells using defined factors.
Autorzy :
Han JK; Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Shin Y; Strategic Center of Cell and Bio Therapy for Heart, Diabetes and Cancer, Seoul National University Hospital, Seoul, South Korea; Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.
Sohn MH; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea; Gong-Wu Genomic Medicine Institute, Seoul National University Bundang Hospital, Seongnam, South Korea; Precision Medicine Center, Seoul National University Bundang Hospital, Seongnam, South Korea; Macrogen Inc., Seoul, South Korea.
Choi SB; Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.
Shin D; Strategic Center of Cell and Bio Therapy for Heart, Diabetes and Cancer, Seoul National University Hospital, Seoul, South Korea; Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.
You Y; Strategic Center of Cell and Bio Therapy for Heart, Diabetes and Cancer, Seoul National University Hospital, Seoul, South Korea; Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.
Shin JY; Gong-Wu Genomic Medicine Institute, Seoul National University Bundang Hospital, Seongnam, South Korea; Precision Medicine Center, Seoul National University Bundang Hospital, Seongnam, South Korea; Macrogen Inc., Seoul, South Korea.
Seo JS; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea; Gong-Wu Genomic Medicine Institute, Seoul National University Bundang Hospital, Seongnam, South Korea; Precision Medicine Center, Seoul National University Bundang Hospital, Seongnam, South Korea; Macrogen Inc., Seoul, South Korea; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.
Kim HS; Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2021 May; Vol. 272, pp. 120781. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadherins*/genetics
Endothelial Cells*
Adult ; Animals ; Epithelial-Mesenchymal Transition ; Fibroblasts ; Humans ; Mice ; Platelet Endothelial Cell Adhesion Molecule-1 ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Gastric cancer-secreted exosomal X26nt increases angiogenesis and vascular permeability by targeting VE-cadherin.
Autorzy :
Chen X; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang S; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Du K; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng N; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen H; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xie G; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ma Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhou Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zeng L; School of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Yang J; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shen L; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Faculty of Medical Laboratory Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Xin Hua Children's Hospital, Shanghai, China.
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Źródło :
Cancer science [Cancer Sci] 2021 May; Vol. 112 (5), pp. 1839-1852. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Capillary Permeability*
Antigens, CD/*metabolism
Cadherins/*metabolism
Exosomes/*metabolism
Neovascularization, Pathologic/*etiology
RNA, Long Noncoding/*metabolism
Stomach Neoplasms/*blood supply
3' Untranslated Regions ; Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Cell Communication ; Cell Movement ; Cell Proliferation ; Endoribonucleases/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Protein Splicing ; Protein-Serine-Threonine Kinases/metabolism ; RNA, Messenger/metabolism ; Stomach Neoplasms/metabolism ; X-Box Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł :
Female-specific synaptic dysfunction and cognitive impairment in a mouse model of PCDH19 disorder.
Autorzy :
Hoshina N; Department of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Johnson-Venkatesh EM; Department of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Hoshina M; Department of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Umemori H; Department of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. .
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Źródło :
Science (New York, N.Y.) [Science] 2021 Apr 16; Vol. 372 (6539).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadherins/*metabolism
Cognitive Dysfunction/*physiopathology
Genetic Diseases, X-Linked/*physiopathology
Mossy Fibers, Hippocampal/*physiopathology
Synapses/*physiology
Animals ; CA3 Region, Hippocampal/physiopathology ; CA3 Region, Hippocampal/ultrastructure ; Cadherins/genetics ; Cognitive Dysfunction/genetics ; Disease Models, Animal ; Epilepsy/genetics ; Epilepsy/physiopathology ; Female ; Genes, X-Linked ; Genetic Diseases, X-Linked/genetics ; Long-Term Potentiation ; Male ; Mice ; Mossy Fibers, Hippocampal/ultrastructure ; Mutation ; Sex Characteristics ; Synapses/ultrastructure ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Side-specific valvular endothelial-interstitial cell mechano-communication via cadherin-11.
Autorzy :
Johnson CL; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States.
Merryman WD; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States. Electronic address: .
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Źródło :
Journal of biomechanics [J Biomech] 2021 Apr 15; Vol. 119, pp. 110253. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Aortic Valve Stenosis*
Cadherins*
Calcinosis*
Mechanotransduction, Cellular*
Animals ; Aortic Valve ; Cells, Cultured ; Endothelial Cells ; Mice
Czasopismo naukowe
Tytuł :
You Talking to Me? Cadherin and Integrin Crosstalk in Biomaterial Design.
Autorzy :
Barcelona-Estaje E; Centre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8QQ, UK.
Dalby MJ; Centre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8QQ, UK.
Cantini M; Centre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8QQ, UK.
Salmeron-Sanchez M; Centre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8QQ, UK.
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Źródło :
Advanced healthcare materials [Adv Healthc Mater] 2021 Mar; Vol. 10 (6), pp. e2002048. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cadherins*
Integrins*
Biocompatible Materials ; Cell Adhesion ; Epithelial-Mesenchymal Transition
Czasopismo naukowe
Tytuł :
The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours.
Autorzy :
Zhao Y; Centre for the Endothelium, Vascular Biology Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Li J; Centre for the Endothelium, Vascular Biology Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Ting KK; Centre for the Endothelium, Vascular Biology Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Chen J; Liver Injury and Cancer Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Coleman P; Centre for the Endothelium, Vascular Biology Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Liu K; Liver Injury and Cancer Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Wan L; Centre for the Endothelium, Vascular Biology Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Moller T; Ranger Biotherapeutics A/S, Vejle, 7100, Denmark.
Vadas MA; Centre for the Endothelium, Vascular Biology Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia.
Gamble JR; Centre for the Endothelium, Vascular Biology Program, Centenary Institute, The University of Sydney, Sydney, 2050, Australia. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2021 Jan 01; Vol. 496, pp. 1-15. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*metabolism
CD8-Positive T-Lymphocytes/*immunology
Cadherins/*metabolism
Endothelium, Vascular/*pathology
Lymphocytes, Tumor-Infiltrating/*immunology
Melanoma, Experimental/*pathology
Oligonucleotides/*pharmacology
beta Catenin/*metabolism
Animals ; Antigens, CD/genetics ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cadherins/antagonists & inhibitors ; Cadherins/genetics ; Cell Proliferation ; Endothelium, Vascular/immunology ; Endothelium, Vascular/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Melanoma, Experimental/immunology ; Melanoma, Experimental/metabolism ; Mice ; Middle Aged ; Neutrophils/immunology ; beta Catenin/genetics
Czasopismo naukowe
Tytuł :
Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR-STAT3 signalling.
Autorzy :
Gao X; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.
Xia X; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.
Li F; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.
Zhang M; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.
Zhou H; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.; Gene Denovo Biotechnology (Guangzhou), Guangzhou, China.
Wu X; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.
Zhong J; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.
Zhao Z; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zhao K; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China.
Liu D; Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xiao F; Department of Scientific Research Section, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xu Q; GenomiCare Biotechnology (Shanghai), Shanghai, China.
Jiang T; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Li B; Department of Biochemistry and Molecular Biology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Cheng SY; The Ken and Ruth Davee Department of Neurology, Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .
Zhang N; Department of Neurosurgery, The First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Brain Function and Disease, Guangdong Translational Medicine Innovation Platform, Guangzhou, China. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2021 Mar; Vol. 23 (3), pp. 278-291. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*metabolism
Brain Neoplasms/*enzymology
Cadherins/*metabolism
Glioblastoma/*enzymology
RNA, Circular/*metabolism
STAT3 Transcription Factor/*metabolism
Animals ; Antigens, CD/genetics ; Antineoplastic Agents/pharmacology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cadherins/genetics ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Glioblastoma/drug therapy ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; Mice, Nude ; Neoplasm Invasiveness ; RNA, Circular/genetics ; STAT3 Transcription Factor/genetics ; Signal Transduction ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Dissecting the Cellular Mechanism of Prostacyclin Analog Iloprost in Reversing Vascular Dysfunction in Scleroderma.
Autorzy :
Tsou PS; University of Michigan, Ann Arbor.
Palisoc PJ; University of Michigan, Ann Arbor.
Flavahan NA; Johns Hopkins University School of Medicine, Baltimore, Maryland.
Khanna D; University of Michigan, Ann Arbor.
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Źródło :
Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2021 Mar; Vol. 73 (3), pp. 520-529. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adherens Junctions/*drug effects
Antigens, CD/*drug effects
Cadherins/*drug effects
Endothelial Cells/*drug effects
Iloprost/*pharmacology
Raynaud Disease/*drug therapy
Scleroderma, Diffuse/*drug therapy
Vasodilator Agents/*pharmacology
Adherens Junctions/metabolism ; Antigens, CD/metabolism ; Cadherins/metabolism ; Capillary Permeability/drug effects ; Case-Control Studies ; Cells, Cultured ; Endothelial Cells/metabolism ; Epithelial-Mesenchymal Transition/drug effects ; Female ; Humans ; Iloprost/therapeutic use ; Male ; Middle Aged ; Neovascularization, Physiologic/drug effects ; Raynaud Disease/etiology ; Raynaud Disease/physiopathology ; Scleroderma, Diffuse/complications ; Scleroderma, Diffuse/physiopathology ; Vasodilator Agents/therapeutic use
Czasopismo naukowe
Tytuł :
uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells.
Autorzy :
Biagioni A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Laurenzana A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Menicacci B; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Peppicelli S; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Andreucci E; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Bianchini F; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Guasti D; Department of Experimental and Clinical Medicine, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy.
Paoli P; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Serratì S; Nanotecnology Laboratory, National Cancer Research Centre, IRCCS 'Giovanni Paolo II', Viale Orazio Flacco, 65, 70124, Bari, Italy.
Mocali A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Calorini L; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Del Rosso M; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Fibbi G; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Chillà A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy. .
Margheri F; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Mar; Vol. 78 (6), pp. 3057-3072. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Antigens, CD/*metabolism
Cadherins/*metabolism
Exosomes/*metabolism
Receptors, Urokinase Plasminogen Activator/*metabolism
Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Cell Line ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Gefitinib/pharmacology ; Gene Editing ; Humans ; Melanoma/metabolism ; Melanoma/pathology ; Mice ; Mice, SCID ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Neovascularization, Physiologic ; Phosphorylation/drug effects ; RNA Interference ; RNA, Small Interfering ; Receptors, Urokinase Plasminogen Activator/antagonists & inhibitors ; Receptors, Urokinase Plasminogen Activator/genetics
Czasopismo naukowe
Tytuł :
PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer.
Autorzy :
Jao TM; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung City, 813, Taiwan.
Fang WH; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan.
Ciou SC; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan.
Yu SL; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan.
Hung YL; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan.
Weng WT; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan.
Lin TY; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan.
Tsai MH; Department of Surgery, Cardinal Tien Hospital, New Taipei City, 231, Taiwan; School of Medicine, Fu-Jen Catholic University, New Taipei City, 242, Taiwan. Electronic address: .
Yang YC; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, 100, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2021 Feb 28; Vol. 499, pp. 290-300. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadherins/*metabolism
Colorectal Neoplasms/*pathology
Tumor Suppressor Proteins/*metabolism
Apoptosis ; Cadherins/genetics ; Cell Line, Tumor ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Epithelial-Mesenchymal Transition ; ErbB Receptors/metabolism ; G1 Phase Cell Cycle Checkpoints ; Gene Knockdown Techniques ; Glycogen Synthase Kinase 3 beta/metabolism ; Humans ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Spheroids, Cellular ; Tumor Suppressor Proteins/genetics ; Wnt Signaling Pathway
Czasopismo naukowe
Tytuł :
HOTAIR Induces Methylation of PCDH10, a Tumor Suppressor Gene, by Regulating DNMT1 and Sponging with miR-148b in Gastric Adenocarcinoma.
Autorzy :
Seo SI; Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.; Department of Medicine, The Graduate School, Yonsei University, Seoul, Korea.
Yoon JH; Division of Gastroenterology, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea.
Byun HJ; Division of Gastroenterology, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul, Korea.
Lee SK; Division of Gastroenterology, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul, Korea. .
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Źródło :
Yonsei medical journal [Yonsei Med J] 2021 Feb; Vol. 62 (2), pp. 118-128.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, Tumor Suppressor*
Adenocarcinoma/*genetics
Cadherins/*genetics
DNA (Cytosine-5-)-Methyltransferase 1/*metabolism
DNA Methylation/*genetics
MicroRNAs/*metabolism
RNA, Long Noncoding/*genetics
Stomach Neoplasms/*genetics
Apoptosis/genetics ; Cadherins/metabolism ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; MicroRNAs/genetics ; Middle Aged ; Neoplasm Invasiveness ; Stomach Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Weakening of interaction networks with aging in tip-link protein induces hearing loss.
Autorzy :
Garg S; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Punjab, India.
Sagar A; Centre de Biochimie Structurale INSERM, CNRS, Université de Montpellier, Montpellier, France.
Singaraju GS; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Punjab, India.
Dani R; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.
Bari NK; Institute of Nano Science and Technology (INST), Phase-10, Sector-64, Mohali, Punjab 160062, India.
Naganathan AN; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.
Rakshit S; Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Punjab, India.; Centre for Protein Science Design and Engineering, Indian Institute of Science Education and Research Mohali, Punjab, India.
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Źródło :
The Biochemical journal [Biochem J] 2021 Jan 15; Vol. 478 (1), pp. 121-134.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadherins/*chemistry
Extracellular Matrix Proteins/*metabolism
Hearing Loss/*metabolism
Proteoglycans/*metabolism
Aging/metabolism ; Aging/pathology ; Cadherins/genetics ; Calorimetry, Differential Scanning ; Circular Dichroism ; Extracellular Matrix Proteins/genetics ; Gene Expression ; Hearing Loss/genetics ; Humans ; Hydrogen Bonding ; Kinetics ; Molecular Dynamics Simulation ; Mutation ; Protein Conformation, beta-Strand ; Protein Interaction Maps ; Proteoglycans/genetics ; Thermodynamics
Czasopismo naukowe
Tytuł :
Distinct roles for prominin-1 and photoreceptor cadherin in outer segment disc morphogenesis in CRISPR-altered X. laevis .
Autorzy :
Carr BJ; Department of Ophthalmology and Visual Sciences, Faculty of Medicine, University of British Columbia, 330-2550 Willow St., Vancouver, British Columbia V5Z 3N9, Canada .
Stanar P; Department of Ophthalmology and Visual Sciences, Faculty of Medicine, University of British Columbia, 330-2550 Willow St., Vancouver, British Columbia V5Z 3N9, Canada.
Moritz OL; Department of Ophthalmology and Visual Sciences, Faculty of Medicine, University of British Columbia, 330-2550 Willow St., Vancouver, British Columbia V5Z 3N9, Canada.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Jan 11; Vol. 134 (1). Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadherins*/genetics
Clustered Regularly Interspaced Short Palindromic Repeats*
AC133 Antigen/genetics ; Animals ; Humans ; Morphogenesis/genetics ; Nerve Tissue Proteins ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Comparative E-Cadherin Digital Expression Analysis in HPV and non-HPV Related Squamous Cell Carcinoma of the Oral Cavity.
Autorzy :
Chrysovergis A; 1 ENT Department, Hippokration Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Papanikolaou V; 1 ENT Department, Hippokration Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Mastronikolis N; ENT Department, Medical School, University of Patras, Patras, Greece.
Spyropoulou D; Department of Radiation Oncology, Medical School, University of Patras, Patras, Greece.
Adamopoulou M; Department of Biomedical Sciences, University of West Attica, Athens, Greece.
Tsiambas E; Department of Cytology, 417 VA Hospital (NIMTS), Athens, Greece; .
Peschos D; Department of Physiology, Medical School, University of Ioannina, Ioannina, Greece.
Ragos V; Dept of Maxillofacial, Medical School, University of Ioannina, Ioannina, Greece.
Kyrodimos E; 1 ENT Department, Hippokration Hospital, National and Kapodistrian University of Athens, Athens, Greece.
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Źródło :
Anticancer research [Anticancer Res] 2021 Jan; Vol. 41 (1), pp. 163-167.
Typ publikacji :
Journal Article
MeSH Terms :
Alphapapillomavirus*
Gene Expression*
Cadherins/*genetics
Carcinoma, Squamous Cell/*etiology
Mouth Neoplasms/*etiology
Papillomavirus Infections/*complications
Biomarkers, Tumor ; Cadherins/metabolism ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Disease Susceptibility ; Female ; Humans ; Immunohistochemistry ; Male ; Mouth Neoplasms/metabolism ; Mouth Neoplasms/pathology ; Neoplasm Grading ; Neoplasm Staging ; Papillomavirus Infections/virology
Czasopismo naukowe
Tytuł :
Prostate-Specific Deletion of Cdh1 Induces Murine Prostatic Inflammation and Bladder Overactivity.
Autorzy :
Pascal LE; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Mizoguchi S; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Chen W; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Rigatti LH; Division of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Igarashi T; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Dhir R; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Tyagi P; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Wu Z; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Yang Z; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
de Groat WC; Department of Pharmacology and Chemical Biology, and University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
DeFranco DB; Department of Pharmacology and Chemical Biology, and University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Yoshimura N; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Wang Z; Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pharmacology and Chemical Biology, and University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
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Źródło :
Endocrinology [Endocrinology] 2021 Jan 01; Vol. 162 (1).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadherins/*metabolism
Lower Urinary Tract Symptoms/*etiology
Prostate/*metabolism
Prostate-Specific Antigen/*metabolism
Prostatitis/*complications
Prostatitis/*genetics
Animals ; Cadherins/genetics ; Gene Deletion ; Inflammation ; Lower Urinary Tract Symptoms/physiopathology ; Male ; Mice ; Prostate/pathology ; Prostatitis/pathology ; Tissue Distribution ; Urinary Bladder/physiopathology
Czasopismo naukowe
Tytuł :
Erythropoietin maintains VE-cadherin expression and barrier function in experimental diabetic retinopathy via inhibiting VEGF/VEGFR2/Src signaling pathway.
Autorzy :
Liu D; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xu H; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China; Department of Ophthalmology, Children's Hospital of Soochow University, Suzhou, China.
Zhang C; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xie H; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Yang Q; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Li W; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China; Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, United States.
Tian H; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Lu L; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xu JY; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xu G; Department of Ophthalmology, the Second Affiliated Hospital of Soochow University, Suzhou, China.
Liu K; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.
Sun X; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.
Xu GT; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. Electronic address: .
Zhang J; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118273. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD/*biosynthesis
Blood-Retinal Barrier/*metabolism
Cadherins/*biosynthesis
Diabetic Retinopathy/*metabolism
Erythropoietin/*pharmacology
Vascular Endothelial Growth Factor A/*metabolism
Vascular Endothelial Growth Factor Receptor-2/*metabolism
src-Family Kinases/*metabolism
Animals ; Antigens, CD/genetics ; Antigens, CD/metabolism ; Blood-Retinal Barrier/drug effects ; Blood-Retinal Barrier/pathology ; Cadherins/genetics ; Cadherins/metabolism ; Capillary Permeability/drug effects ; Diabetes Mellitus, Experimental/metabolism ; Diabetic Retinopathy/pathology ; Down-Regulation ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Male ; Rats ; Rats, Sprague-Dawley ; Recombinant Proteins/pharmacology ; Retinal Vessels/drug effects ; Retinal Vessels/metabolism ; Retinal Vessels/pathology
Czasopismo naukowe

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