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Tytuł:
Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice.
Autorzy:
Fang JL; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA. .
Vanlandingham MM; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Olson GR; Toxicologic Pathology Associates, Inc., National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Maisha MP; Office of Scientific Coordination, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Felton R; Office of Scientific Coordination, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Beland FA; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
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Źródło:
Archives of toxicology [Arch Toxicol] 2024 Jan; Vol. 98 (1), pp. 335-345. Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Triclosan*/toxicity
Adenoma, Liver Cell*
Carcinoma, Hepatocellular*
Liver Neoplasms*
Rats ; Humans ; Mice ; Male ; Female ; Animals ; Rats, Inbred F344 ; Carcinogenicity Tests ; Mice, Inbred Strains ; Ethanol ; Body Weight
Czasopismo naukowe
Tytuł:
ACADL-YAP axis activity in non-small cell lung cancer carcinogenicity.
Autorzy:
Chen, Kegong (AUTHOR)
Hong, Chunqiao (AUTHOR)
Kong, Weibo (AUTHOR)
Li, Guanghua (AUTHOR)
Liu, Zhuang (AUTHOR)
Zhu, Kechao (AUTHOR)
Lu, Chen (AUTHOR)
Si, Panpan (AUTHOR)
Gao, Pan (AUTHOR)
Ning, Guangyao (AUTHOR)
Zhang, Renquan (AUTHOR)
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Źródło:
Cancer Cell International. 2/24/2024, Vol. 24 Issue 1, p1-14. 14p.
Czasopismo naukowe
Tytuł:
Quality Control Optimization for Minimizing Security Risks Associated with Mesenchymal Stromal Cell-Based Product Development.
Autorzy:
Rebelatto CLK; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.; National Institute of Science and Technology for Regenerative Medicine-INCT-REGENERA, Rio de Janeiro 21941-599, Brazil.
Boldrini-Leite LM; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.; National Institute of Science and Technology for Regenerative Medicine-INCT-REGENERA, Rio de Janeiro 21941-599, Brazil.
Daga DR; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.; National Institute of Science and Technology for Regenerative Medicine-INCT-REGENERA, Rio de Janeiro 21941-599, Brazil.
Marsaro DB; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.; National Institute of Science and Technology for Regenerative Medicine-INCT-REGENERA, Rio de Janeiro 21941-599, Brazil.
Vaz IM; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.; National Institute of Science and Technology for Regenerative Medicine-INCT-REGENERA, Rio de Janeiro 21941-599, Brazil.
Jamur VR; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.; National Institute of Science and Technology for Regenerative Medicine-INCT-REGENERA, Rio de Janeiro 21941-599, Brazil.
de Aguiar AM; Laboratory of Basic Biology of Stem Cells, Carlos Chagas Institute-Fiocruz-Paraná, Curitiba 81350-010, Brazil.
Vieira TB; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.
Furman BP; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.
Aguiar CO; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.
Brofman PRS; Core for Cell Technology, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba 80215-901, Brazil.; National Institute of Science and Technology for Regenerative Medicine-INCT-REGENERA, Rio de Janeiro 21941-599, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 19; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 19.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Assay*
Mesenchymal Stem Cells*
Humans ; Reproducibility of Results ; Carcinogenicity Tests ; Endotoxins ; Quality Control
Czasopismo naukowe
Tytuł:
Carcinogenicity of aspartame, methyleugenol, and isoeugenol.
Autorzy:
Riboli E; International Agency for Research on Cancer, Lyon, France.
Beland FA; International Agency for Research on Cancer, Lyon, France.
Lachenmeier DW; International Agency for Research on Cancer, Lyon, France.
Marques MM; International Agency for Research on Cancer, Lyon, France.
Phillips DH; International Agency for Research on Cancer, Lyon, France.
Schernhammer E; International Agency for Research on Cancer, Lyon, France.
Afghan A; International Agency for Research on Cancer, Lyon, France.
Assunção R; International Agency for Research on Cancer, Lyon, France.
Caderni G; International Agency for Research on Cancer, Lyon, France.
Corton JC; International Agency for Research on Cancer, Lyon, France.
de Aragão Umbuzeiro G; International Agency for Research on Cancer, Lyon, France.
de Jong D; International Agency for Research on Cancer, Lyon, France.
Deschasaux-Tanguy M; International Agency for Research on Cancer, Lyon, France.
Hodge A; International Agency for Research on Cancer, Lyon, France.
Ishihara J; International Agency for Research on Cancer, Lyon, France.
Levy DD; International Agency for Research on Cancer, Lyon, France.
Mandrioli D; International Agency for Research on Cancer, Lyon, France.
McCullough ML; International Agency for Research on Cancer, Lyon, France.
McNaughton SA; International Agency for Research on Cancer, Lyon, France.
Morita T; International Agency for Research on Cancer, Lyon, France.
Nugent AP; International Agency for Research on Cancer, Lyon, France.
Ogawa K; International Agency for Research on Cancer, Lyon, France.
Pandiri AR; International Agency for Research on Cancer, Lyon, France.
Sergi CM; International Agency for Research on Cancer, Lyon, France.
Touvier M; International Agency for Research on Cancer, Lyon, France.
Zhang L; International Agency for Research on Cancer, Lyon, France.
Benbrahim-Tallaa L; International Agency for Research on Cancer, Lyon, France.
Chittiboyina S; International Agency for Research on Cancer, Lyon, France.
Cuomo D; International Agency for Research on Cancer, Lyon, France.
DeBono NL; International Agency for Research on Cancer, Lyon, France.
Debras C; International Agency for Research on Cancer, Lyon, France.
de Conti A; International Agency for Research on Cancer, Lyon, France.
El Ghissassi F; International Agency for Research on Cancer, Lyon, France.
Fontvieille E; International Agency for Research on Cancer, Lyon, France.
Harewood R; International Agency for Research on Cancer, Lyon, France.
Kaldor J; International Agency for Research on Cancer, Lyon, France.
Mattock H; International Agency for Research on Cancer, Lyon, France.
Pasqual E; International Agency for Research on Cancer, Lyon, France.
Rigutto G; International Agency for Research on Cancer, Lyon, France.
Simba H; International Agency for Research on Cancer, Lyon, France.
Suonio E; International Agency for Research on Cancer, Lyon, France.
Viegas S; International Agency for Research on Cancer, Lyon, France.
Wedekind R; International Agency for Research on Cancer, Lyon, France.
Schubauer-Berigan MK; International Agency for Research on Cancer, Lyon, France.
Madia F; International Agency for Research on Cancer, Lyon, France.
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Źródło:
The Lancet. Oncology [Lancet Oncol] 2023 Aug; Vol. 24 (8), pp. 848-850. Date of Electronic Publication: 2023 Jul 13.
Typ publikacji:
Wiadomości
MeSH Terms:
Aspartame*/adverse effects
Eugenol*
Humans ; Carcinogenicity Tests
Periodyk
Tytuł:
Evaluation of functional candidate biomarkers of non-genotoxic hepatocarcinogenicity in human liver spheroid co-cultures.
Autorzy:
Dos Santos Rodrigues B; Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Leroy K; Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Mihajlovic M; Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
De Boever S; Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Vanbellingen S; Entity of Neuro-Aging and Viro-Immunotherapy, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussels, Belgium.
Cogliati B; School of Veterinary Medicine and Animal Science, Department of Pathology, University of São Paulo, São Paulo, Brazil.
Aerts JL; Entity of Neuro-Aging and Viro-Immunotherapy, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussels, Belgium.
Vinken M; Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium. .
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Źródło:
Archives of toxicology [Arch Toxicol] 2023 Jun; Vol. 97 (6), pp. 1739-1751. Date of Electronic Publication: 2023 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Proteomics*
Carcinogens*/toxicity
Humans ; Coculture Techniques ; Liver ; Hepatocytes ; Carcinogenicity Tests/methods
Czasopismo naukowe
Tytuł:
Research progress on the carcinogenicity of metal nanomaterials.
Autorzy:
Liu L; Key Laboratory of Environment Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China.
Kong L; Key Laboratory of Environment Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China.
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Źródło:
Journal of applied toxicology : JAT [J Appl Toxicol] 2021 Sep; Vol. 41 (9), pp. 1334-1344. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Carcinogenicity Tests*
Carcinogens/*toxicity
Metal Nanoparticles/*toxicity
Nanostructures/*toxicity
Animals ; Humans
Czasopismo naukowe
Tytuł:
Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice.
Autorzy:
Kim, Na-Won (AUTHOR)
Seo, Sun-Min (AUTHOR)
Yoo, Eun-Seon (AUTHOR)
Kang, Ah-Reum (AUTHOR)
Lee, Ji-Hun (AUTHOR)
Lee, Jae-Hoon (AUTHOR)
Kang, Byeong-Cheol (AUTHOR)
Lee, Han-Woong (AUTHOR)
Choi, Yang-Kyu (AUTHOR)
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Źródło:
PLoS ONE. 1/6/2023, Vol. 17 Issue 1, p1-15. 15p.
Czasopismo naukowe
Tytuł:
An Adverse Outcome Pathway Network for Chemically Induced Oxidative Stress Leading to (Non)genotoxic Carcinogenesis.
Autorzy:
Veltman CHJ; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, The Netherlands.; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research (LACDR), Leiden University, 2333 CC Leiden, The Netherlands.
Pennings JLA; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, The Netherlands.
van de Water B; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research (LACDR), Leiden University, 2333 CC Leiden, The Netherlands.
Luijten M; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, The Netherlands.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2023 Jun 19; Vol. 36 (6), pp. 805-817. Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Adverse Outcome Pathways*
Neoplasms*/chemically induced
Animals ; Humans ; Carcinogens/toxicity ; Carcinogens/metabolism ; Carcinogenesis/chemically induced ; Oxidative Stress ; DNA Damage ; Carcinogenicity Tests
Czasopismo naukowe
Tytuł:
Letter to "Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose-response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose-response data".
Autorzy:
Thompson CM; ToxStrategies, Inc, Katy, Texas, USA.
Proctor DM; ToxStrategies, Inc, Mission Viejo, California, USA.
Harris MA; ToxStrategies, Inc, Katy, Texas, USA.
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Źródło:
Environmental and molecular mutagenesis [Environ Mol Mutagen] 2023 Apr; Vol. 64 (4), pp. 259-260. Date of Electronic Publication: 2023 Apr 08.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Mutagens*/toxicity
Carcinogens*/toxicity
Mutagenesis ; Mutagenicity Tests ; Carcinogenicity Tests
Raport
Tytuł:
Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action.
Autorzy:
Chapman KE; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK. .
Wilde EC; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Chapman FM; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Verma JR; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Shah UK; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Stannard LM; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Seager AL; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Tonkin JA; College of Engineering, Swansea University, Bay Campus, Swansea, SA1 8EN, UK.
Brown MR; College of Engineering, Swansea University, Bay Campus, Swansea, SA1 8EN, UK.
Doherty AT; Discovery Safety, AstraZeneca, DSM, Darwin Building, Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, UK.
Johnson GE; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Doak SH; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
Jenkins GJS; In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea University, Singleton Campus, Swansea, SA2 8PP, UK.
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Źródło:
Archives of toxicology [Arch Toxicol] 2021 Jan; Vol. 95 (1), pp. 321-336. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenicity Tests*
Endpoint Determination*
Research Design*
Carcinogens/*toxicity
Cell Cycle Checkpoints/drug effects ; Cell Line ; Cell Shape/drug effects ; Energy Metabolism/drug effects ; Gene Expression Regulation/drug effects ; Humans ; Micronuclei, Chromosome-Defective/chemically induced ; Micronucleus Tests ; Phosphorylation ; Risk Assessment ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł:
Clear evidence of the carcinogenic potential of anthracene: A 2-year feeding study in rats and mice.
Autorzy:
Takeda T; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Kanagawa, Japan.
Suzuki M; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Kanagawa, Japan.
Kano H; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Kanagawa, Japan.
Matsumoto M; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Kanagawa, Japan.
Umeda Y; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Kanagawa, Japan.
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Źródło:
Environmental toxicology [Environ Toxicol] 2023 Mar; Vol. 38 (4), pp. 709-726. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Kidney Neoplasms*/pathology
Liver Neoplasms*/pathology
Humans ; Rats ; Mice ; Animals ; Male ; Female ; Carcinogens/toxicity ; Rats, Inbred F344 ; Mice, Inbred Strains ; Carcinogenicity Tests ; Carcinogenesis
Czasopismo naukowe
Tytuł:
Multi-organ carcinogenicity by inhalation exposure to 2-Bromopropane in rats.
Autorzy:
Senoh H; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Kasai T; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Hirai S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Furukawa Y; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Misumi K; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Goto Y; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Takanobu K; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Matsumoto M; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Fukushima S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
Aiso S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Japan.
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Źródło:
Journal of occupational health [J Occup Health] 2023 Jan; Vol. 65 (1), pp. e12388.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*/chemically induced
Adenoma*/chemically induced
Humans ; Mice ; Rats ; Animals ; Male ; Female ; Rats, Inbred F344 ; Mice, Inbred Strains ; Carcinogenicity Tests ; Inhalation Exposure/adverse effects
Czasopismo naukowe
Tytuł:
Carcinogenicity and chronic toxicity of butyl methacrylate in rats and mice by a two-year inhalation study.
Autorzy:
Furukawa Y; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Hirai S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Kasai T; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Senoh H; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Takanobu K; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Sasaki T; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Kano H; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Matsumoto M; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
Aiso S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
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Źródło:
The Journal of toxicological sciences [J Toxicol Sci] 2023; Vol. 48 (5), pp. 227-241.
Typ publikacji:
Journal Article
MeSH Terms:
Adenoma, Liver Cell*
Liver Neoplasms*/pathology
Rats ; Mice ; Male ; Female ; Animals ; Rats, Inbred F344 ; Mice, Inbred Strains ; Carcinogenicity Tests
Czasopismo naukowe
Tytuł:
Rat Tumour Histopathology Associated with Experimental Chronic Dietary Exposure to Ochratoxin A in Prediction of the Mycotoxin's Risk for Human Cancers.
Autorzy:
Herman D; Pathology Department, County Hospital Timisoara, 300736 Timisoara, Romania.
Mantle P; Centre for Environmental Policy, Imperial College London, London SW7 2AZ, UK.
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Źródło:
Toxins [Toxins (Basel)] 2021 Mar 12; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenicity Tests*
Kidney Neoplasms/*chemically induced
Ochratoxins/*toxicity
Testicular Neoplasms/*chemically induced
Animals ; Dietary Exposure ; Humans ; Keratins/metabolism ; Kidney Neoplasms/metabolism ; Kidney Neoplasms/pathology ; Male ; Neprilysin/metabolism ; Rats, Inbred F344 ; Risk Assessment ; Risk Factors ; Testicular Neoplasms/metabolism ; Testicular Neoplasms/pathology ; Time Factors ; Vimentin/metabolism ; Rats
Czasopismo naukowe
Tytuł:
The Cell Transformation Assay: A Historical Assessment of Current Knowledge of Applications in an Integrated Approach to Testing and Assessment for Non-Genotoxic Carcinogens.
Autorzy:
Colacci A; Agency for Prevention, Environment and Energy, Emilia-Romagna (Arpae), Via Po 5, I-40139 Bologna, Italy.
Corvi R; European Commission, Joint Research Centre (JRC), I-21027 Ispra, Italy.
Ohmori K; Chemical Division, Kanagawa Prefectural Institute of Public Health, Chigasaki 253-0087, Japan.; Research Initiatives and Promotion Organization, Yokohama National University, Yokohama 240-8501, Japan.
Paparella M; Division of Medical Biochemistry, Biocenter, Medical University of Innsbruck, A-6020 Innbruck, Austria.
Serra S; Agency for Prevention, Environment and Energy, Emilia-Romagna (Arpae), Via Po 5, I-40139 Bologna, Italy.
Da Rocha Carrico I; European Commission, Joint Research Centre (JRC), I-21027 Ispra, Italy.
Vasseur P; Universite de Lorraine, CNRS UMR 7360 LIEC, Laboratoire Interdisciplinaire des Environnements Continentaux, 57070 Metz, France.
Jacobs MN; Radiation, Chemical and Environmental Hazards, UK Health Security Agency, Harwell Science and Innovation Campus, Chilton OX11 0RQ, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 16; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinogens*/toxicity
Neoplasms*
Humans ; Carcinogenicity Tests/methods ; Cell Transformation, Neoplastic/genetics ; Carcinogenesis/genetics
Czasopismo naukowe
Tytuł:
The 2-year rodent bioassay in drug and chemical carcinogenesis testing: Sensitivity, according to the framework of carcinogenic action.
Autorzy:
Suarez-Torres JD; Department of Pharmacy, Universidad Nacional de Colombia, Bogotá, Colombia.; Department of Toxicology, Universidad Nacional de Colombia, Bogotá, Colombia.; Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.
Jimenez-Orozco FA; Department of Pharmacology, Faculty of Medicine, Universidad Nacional Autónoma de México, Ciudad de Mexico, Mexico.
Ciangherotti CE; Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.; Laboratory of Neuropeptides, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Jul; Vol. 30 (6), pp. 462-475. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Assay*
Carcinogenicity Tests*
Carcinogens/*toxicity
Cell Transformation, Neoplastic/*chemically induced
Neoplasms/*chemically induced
Animals ; Databases, Factual ; Female ; Humans ; Male ; Mice ; Rats ; Risk Assessment ; Time Factors
Czasopismo naukowe
Tytuł:
Analyses of Transcriptomics Cell Signalling for Pre-Screening Applications in the Integrated Approach for Testing and Assessment of Non-Genotoxic Carcinogens.
Autorzy:
Oku Y; The Organisation for Economic Cooperation and Development (OECD), 2 Rue Andre Pascal, 75016 Paris, France.
Madia F; European Commission, Joint Research Centre (JRC), Via Enrico Fermi, 2749, 21027 Ispra, Italy.
Lau P; Istituto Italiano di Tecnologia, 16163 Genova, Italy.
Paparella M; Institute of Medical Biochemistry, Biocenter, Medical University of Innsbruck, Innrain 80, 6020 Innbruck, Austria.
McGovern T; US Food and Drug Administration (FDA), 10903 New Hampshire Avenue, Silver Spring, MD 20901, USA.
Luijten M; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, Bilthoven, 3721 MA Utrecht, The Netherlands.
Jacobs MN; Centre for Radiation, Chemical and Environmental Hazard (CRCE), Public Health England (PHE), Chilton OX11 0RQ, Oxfordshire, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 22; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinogens*/toxicity
Transcriptome*
Humans ; Biological Assay ; Carcinogenesis ; Carcinogenicity Tests/methods
Czasopismo naukowe
Tytuł:
Virtual Extensive Read-Across: A New Open-Access Software for Chemical Read-Across and Its Application to the Carcinogenicity Assessment of Botanicals.
Autorzy:
Viganò, Edoardo Luca (AUTHOR)
Colombo, Erika (AUTHOR)
Raitano, Giuseppa (AUTHOR)
Manganaro, Alberto (AUTHOR)
Sommovigo, Alessio (AUTHOR)
Dorne, Jean Lou CM (AUTHOR)
Benfenati, Emilio (AUTHOR)
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Źródło:
Molecules. Oct2022, Vol. 27 Issue 19, p6605. 13p.
Czasopismo naukowe

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