Temat: "CCAAT-Enhancer-Binding Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer.
Autorzy:: Zhang X; Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai JiaoTong University School of Medicine, 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092, China.
Zheng X; Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai JiaoTong University School of Medicine, 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092, China.
Ying X; Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai JiaoTong University School of Medicine, 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092, China.
Xie W; Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai JiaoTong University School of Medicine, 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092, China.
Yin Y; Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai JiaoTong University School of Medicine, 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092, China.
Wang X; Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai JiaoTong University School of Medicine, 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2023 May 20; Vol. 21 (1), pp. 334. Date of Electronic Publication: 2023 May 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amino Acid Transport System y+*/genetics
Ferroptosis*/genetics
Ovarian Neoplasms*/genetics
CCAAT-Enhancer-Binding Proteins*/genetics
Animals ; Female ; Humans ; Mice ; Biological Assay ; Cell Line, Tumor ; Gene Expression Regulation

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Skocz do pozycji: 2.

Tytuł:: C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC.
Autorzy:: Hartl L; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.
Roelofs JJTH; Department of Pathology, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Dijk F; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Department of Pathology, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Bijlsma MF; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.
Duitman J; Department of Pulmonary Medicine, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Department of Experimental Immunology, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Amsterdam Infection & Immunity, Inflammatory Diseases, 1105 AZ Amsterdam, The Netherlands.
Spek CA; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology and Immunology, 1081 HV Amsterdam, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 12; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:: Journal Article
MeSH Terms:: CCAAT-Enhancer-Binding Proteins*/genetics
CCAAT-Enhancer-Binding Proteins*/metabolism
Gene Expression Regulation*/genetics
Gene Expression Regulation*/physiology
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/genetics
Carcinoma, Pancreatic Ductal*/metabolism
Carcinoma, Pancreatic Ductal*/pathology
Humans ; CCAAT-Enhancer-Binding Protein-beta/genetics ; CCAAT-Enhancer-Binding Protein-beta/metabolism ; CCAAT-Enhancer-Binding Protein-delta/genetics ; CCAAT-Enhancer-Binding Protein-delta/metabolism ; Lymph Nodes/metabolism ; Lymph Nodes/pathology ; Lymphatic Metastasis/genetics ; Lymphatic Metastasis/pathology ; Lymphatic Metastasis/physiopathology ; Prognosis

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Skocz do pozycji: 3.

Tytuł:: The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
Autorzy:: Xue Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Zhang Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Zhao R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Liu X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Grützmann K; Core Unit for Molecular Tumour Diagnostics (CMTD), National Center for Tumour Diseases (NCT) Dresden, Dresden, Germany.; Institute for Medical Informatics and Biometry, Medical Faculty, TU Dresden, Dresden, Germany.
Klink B; Department of Genetics, Laboratoire National de Santé, Dudelange, Luxembourg.
Zhang X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Wang S; Department of Neurosurgery, NYU Grossman School of Medicine, New York, NY, 10016, USA.
Zhao W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Sun Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Han M; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Wang X; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hu Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Liu X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Yang N; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Qiu C; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.; Department of Radiation Oncology, Qilu Hospital of Shandong University, Jinan, China.
Li W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Huang B; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Li X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Bjerkvig R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, 5009, Norway.
Wang J; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China. .; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China. .; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, 5009, Norway. .
Zhou W; Department of Blood Transfusion, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jan 22; Vol. 43 (1), pp. 25. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glioma*
Dopamine Antagonists*/metabolism
Dopamine Antagonists*/pharmacology
Proto-Oncogene Proteins c-myc*/drug effects
Proto-Oncogene Proteins c-myc*/metabolism
Animals ; Humans ; Mice ; Brain ; CCAAT-Enhancer-Binding Proteins/drug effects ; CCAAT-Enhancer-Binding Proteins/metabolism ; Dopamine ; Mice, Nude ; Multigene Family ; Receptors, Dopamine D1/antagonists & inhibitors ; Ubiquitin-Protein Ligases/drug effects ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 4.

Tytuł:: RUNX1/CEBPA Mutation in Acute Myeloid Leukemia Promotes Hypermethylation and Indicates for Demethylation Therapy.
Autorzy:: Romanova EI; Institute of Bioengineering, Research Center of Biotechnology, Russian Academy of Science, 117312 Moscow, Russia.
Zubritskiy AV; Institute of Bioengineering, Research Center of Biotechnology, Russian Academy of Science, 117312 Moscow, Russia.
Lioznova AV; Institute of Bioengineering, Research Center of Biotechnology, Russian Academy of Science, 117312 Moscow, Russia.
Ogunleye AJ; Department of Biomedical Physics. Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Golotin VA; Institute of Cytology, RAS, Laboratory of Molecular Medicine, 194064 St. Petersburg, Russia.; State Research Institute of Lake and River Fisheries, 199053 St. Petersburg, Russia.
Guts AA; INSERM UMR1231, University of Burgundy Franche-Comté, 21078 Dijon, France.; Institute of Pharmacy, Sechenov University, 119435 Moscow, Russia.
Lennartsson A; Department of Biosciences and Nutrition, Karolinska Instituten, 141 83 Huddinge, Sweden.
Demidov ON; Institute of Cytology, RAS, Laboratory of Molecular Medicine, 194064 St. Petersburg, Russia.; INSERM UMR1231, University of Burgundy Franche-Comté, 21078 Dijon, France.; Sirius University of Science and Technology, 354340 Sochi, Russia.
Medvedeva YA; Institute of Bioengineering, Research Center of Biotechnology, Russian Academy of Science, 117312 Moscow, Russia.; Department of Biomedical Physics. Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 27; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 27.
Typ publikacji:: Journal Article
MeSH Terms:: CCAAT-Enhancer-Binding Proteins*/genetics
CCAAT-Enhancer-Binding Proteins*/metabolism
Core Binding Factor Alpha 2 Subunit*/genetics
Core Binding Factor Alpha 2 Subunit*/metabolism
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
DNA/genetics ; DNA/metabolism ; DNA Methylation/genetics ; Demethylation/drug effects ; Humans ; Mutation

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Skocz do pozycji: 5.

Tytuł:: Downregulation of DNA methylation enhances differentiation of THP-1 cells and induces M1 polarization of differentiated macrophages.
Autorzy:: Park J; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea.
Luo Y; College of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.
Park JW; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea.
Kim SH; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea.
Hong YJ; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea.
Lim Y; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea.
Seo YJ; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea.
Bae J; College of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.
Seo SB; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 12; Vol. 13 (1), pp. 13132. Date of Electronic Publication: 2023 Aug 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Methylation*
DNA (Cytosine-5-)-Methyltransferases*/genetics
DNA (Cytosine-5-)-Methyltransferases*/metabolism
Humans ; Animals ; Mice ; Down-Regulation ; THP-1 Cells ; CCAAT-Enhancer-Binding Proteins/genetics ; CCAAT-Enhancer-Binding Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; DNA (Cytosine-5-)-Methyltransferase 1/genetics ; DNA (Cytosine-5-)-Methyltransferase 1/metabolism ; Cell Differentiation/genetics ; Hematopoiesis ; Macrophages/metabolism

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Skocz do pozycji: 6.

Tytuł:: Enhanced Transcriptional Signature and Expression of Histone-Modifying Enzymes in Salivary Gland Tumors.
Autorzy:: Manou M; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Loupis T; Haematology Research Laboratory, Clinical, Experimental Surgery and Translational Research Center, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
Vrachnos DM; Haematology Research Laboratory, Clinical, Experimental Surgery and Translational Research Center, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
Katsoulas N; First Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Theocharis S; First Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Kanakoglou DS; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Basdra EK; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Piperi C; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Papavassiliou AG; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Oct 11; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:: Journal Article
MeSH Terms:: Histones*/metabolism
Salivary Gland Neoplasms*/genetics
Humans ; Chromatin ; Methyltransferases/metabolism ; Epigenesis, Genetic ; Protein-Arginine N-Methyltransferases/metabolism ; Repressor Proteins/metabolism ; CCAAT-Enhancer-Binding Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Histone Deacetylases/metabolism

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Skocz do pozycji: 7.

Tytuł:: Inhibition of abnormal C/EBPβ/α-Syn signaling pathway through activation of Nrf2 ameliorates Parkinson's disease-like pathology.
Autorzy:: Lin Z; Department of Physiology, School of Medicine, Jinan University, Guangzhou, China.
Huang L; Department of Physiology, School of Medicine, Jinan University, Guangzhou, China.
Cao Q; Department of Physiology, School of Medicine, Jinan University, Guangzhou, China.
Luo H; Department of Physiology, School of Medicine, Jinan University, Guangzhou, China.
Yao W; Guangzhou Key Laboratory of Formula-pattern Research Center, School of Traditional Chinese Medicine, Jinan University, Guangzhou, China.
Zhang JC; Department of Physiology, School of Medicine, Jinan University, Guangzhou, China.; Institute of Brain Science and Brain-inspired Research, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Oct; Vol. 22 (10), pp. e13958. Date of Electronic Publication: 2023 Aug 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neuroblastoma*/pathology
Parkinson Disease*/metabolism
Animals ; Humans ; Mice ; Dopaminergic Neurons/metabolism ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Signal Transduction ; alpha-Synuclein/metabolism ; CCAAT-Enhancer-Binding Proteins/metabolism

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Skocz do pozycji: 8.

Tytuł:: Natural and Synthetic Anticancer Epidrugs Targeting the Epigenetic Integrator UHRF1.
Autorzy:: Ashraf W; Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan 60800, Pakistan.
Ahmad T; Institut Pour L'avancée des Biosciences, Centre de Recherche UGA, INSERM U1209, CNRS 5309, Université Grenoble Alpes, 38058 Grenoble, France.
Reynoird N; Institut Pour L'avancée des Biosciences, Centre de Recherche UGA, INSERM U1209, CNRS 5309, Université Grenoble Alpes, 38058 Grenoble, France.
Hamiche A; Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Equipe Labellisée Ligue Contre le Cancer, 67401 Illkirch, France.
Mély Y; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Faculté de Pharmacie, Université de Strasbourg, 67401 Illkirch, France.
Bronner C; Department of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Equipe Labellisée Ligue Contre le Cancer, 67401 Illkirch, France.
Mousli M; Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Faculté de Pharmacie, Université de Strasbourg, 67401 Illkirch, France.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 10; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Carcinogenesis*
Cell Transformation, Neoplastic*
Humans ; Apoptosis ; Cell Cycle ; Epigenesis, Genetic ; CCAAT-Enhancer-Binding Proteins/genetics ; Ubiquitin-Protein Ligases/genetics

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Skocz do pozycji: 9.

Tytuł:: The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis.
Autorzy:: Yang R; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Zhou Y; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Zhang T; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Wang S; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Wang J; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Cheng Y; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Li H; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Jiang W; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.
Yang Z; Department of pathology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.
Zhang X; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2023 Jul 05; Vol. 21 (7), pp. e3001862. Date of Electronic Publication: 2023 Jul 05 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ferroptosis*
Liver Neoplasms*
Humans ; Transcription Factors/metabolism ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Gene Expression Regulation ; High Mobility Group Proteins/metabolism ; CCAAT-Enhancer-Binding Proteins/genetics ; CCAAT-Enhancer-Binding Proteins/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 10.

Tytuł:: CCAAT/Enhancer-Binding Protein ε Antagonism of GATA-1 Transcriptional Activity in the Eosinophil Is Mediated by a Unique N-Terminal Repression Domain, Is Independent of Sumoylation and Does Not Require DNA Binding.
Autorzy:: Stankiewicz MJ; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.; UW Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Du J; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
Martinico D; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.; College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
Ackerman SJ; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 24; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 24.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Sumoylation*
CCAAT-Enhancer-Binding Proteins/*metabolism
Eosinophils/*pathology
GATA1 Transcription Factor/*antagonists & inhibitors
Leukemia, Myeloid, Acute/*pathology
Myelin Basic Protein/*metabolism
CCAAT-Enhancer-Binding Proteins/genetics ; Cell Differentiation ; Cell Nucleus ; Eosinophils/immunology ; Eosinophils/metabolism ; GATA1 Transcription Factor/genetics ; GATA1 Transcription Factor/metabolism ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/immunology ; Leukemia, Myeloid, Acute/metabolism ; Myelin Basic Protein/genetics ; Promoter Regions, Genetic ; Protein Interaction Domains and Motifs ; Tumor Cells, Cultured

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Skocz do pozycji: 11.

Tytuł:: MTL-CEBPA Combined with Immunotherapy or RFA Enhances Immunological Anti-Tumor Response in Preclinical Models.
Autorzy:: Huang KW; Hepatitis Research Center, Department of Surgery, National Taiwan University Hospital, College of Medicine, Taipei 100, Taiwan.; Centre of Mini-Invasive Interventional Oncology, National Taiwan University Hospital, Taipei 100, Taiwan.
Tan CP; MiNA Therapeutics Ltd., London W12 0BZ, UK.
Reebye V; MiNA Therapeutics Ltd., London W12 0BZ, UK.; Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK.
Chee CE; Department of Haemato-Oncology, National University Cancer Institute, Singapore 119077, Singapore.
Zacharoulis D; Department of General Surgery, University Hospital of Larissa, 41110 Larissa, Greece.
Habib R; MiNA Therapeutics Ltd., London W12 0BZ, UK.
Blakey DC; MiNA Therapeutics Ltd., London W12 0BZ, UK.
Rossi JJ; Department of Molecular and Cellular Biology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Habib N; MiNA Therapeutics Ltd., London W12 0BZ, UK.; Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK.
Sodergren MH; Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 25; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 25.
Typ publikacji:: Journal Article
MeSH Terms:: CCAAT-Enhancer-Binding Proteins/*genetics
Carcinoma, Hepatocellular/*drug therapy
Colonic Neoplasms/*drug therapy
Immune Checkpoint Inhibitors/*therapeutic use
Liver Neoplasms/*drug therapy
Lymphocytes, Tumor-Infiltrating/*drug effects
RNA, Double-Stranded/*therapeutic use
Animals ; CCAAT-Enhancer-Binding Proteins/metabolism ; Carcinoma, Hepatocellular/surgery ; Cell Line, Tumor ; Cells, Cultured ; Colonic Neoplasms/surgery ; Liver Neoplasms/immunology ; Liver Neoplasms/radiotherapy ; Lymphocytes, Tumor-Infiltrating/immunology ; Mice ; Mice, Inbred BALB C ; Radiofrequency Ablation ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/immunology

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Skocz do pozycji: 12.

Tytuł:: The Novel Role of Zfp296 in Mammalian Embryonic Genome Activation as an H3K9me3 Modulator.
Autorzy:: Gao L; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Zhang Z; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Zheng X; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Wang F; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Deng Y; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Zhang Q; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Wang G; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Zhang Y; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.
Liu X; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.; State Key Laboratory for Biology of Livestock, Northwest A&F University, Xianyang 712100, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 12; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 12.
Typ publikacji:: Journal Article
MeSH Terms:: Embryonic Development*/genetics
Histones*/genetics
Histones*/metabolism
Embryo, Mammalian*
Animals ; Cattle ; Humans ; Mice ; CCAAT-Enhancer-Binding Proteins/metabolism ; DNA Helicases/metabolism ; Mouse Embryonic Stem Cells/metabolism ; Nuclear Proteins/metabolism ; Sheep ; Swine ; Transcription Factors/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Zygote/metabolism

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Skocz do pozycji: 13.

Tytuł:: Clinical Significance of bZIP In-Frame CEBPA-Mutated Normal Karyotype Acute Myeloid Leukemia.
Autorzy:: Ahn SY; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Kim T; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada.; Department of Computer Science, University of Toronto, Toronto, Canada.
Kim M; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Song GY; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Jung SH; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Yang DH; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Lee JJ; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Kim MY; Genomic Research Center for Hematopoietic Diseases, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Jung CW; Division of Hematology-Oncology, Samsung Medical Center, Seoul, Korea.
Jang JH; Division of Hematology-Oncology, Samsung Medical Center, Seoul, Korea.
Kim HJ; Department of Hematology, Cancer Research Institute, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Moon JH; Department of Hematology-Oncology, Kyungpook National University Hospital, Daegu, Korea.
Sohn SK; Department of Hematology-Oncology, Kyungpook National University Hospital, Daegu, Korea.
Won JH; Department of Hematology-Oncology, Soon Chun Hyang University Hospital, Seoul, Korea.
Kim SH; Department of Hematology-Oncology, Dong-A University College of Medicine, Busan, Korea.
Kim HJ; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.; Genomic Research Center for Hematopoietic Diseases, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Ahn JS; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.; Genomic Research Center for Hematopoietic Diseases, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Kim DDH; Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada.; Pokaż więcej
Źródło:: Cancer research and treatment [Cancer Res Treat] 2023 Jul; Vol. 55 (3), pp. 1011-1022. Date of Electronic Publication: 2023 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: CCAAT-Enhancer-Binding Protein-alpha*/genetics
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/therapy
Humans ; Clinical Relevance ; Disease-Free Survival ; Nucleophosmin ; Mutation ; Prognosis ; Karyotype ; CCAAT-Enhancer-Binding Proteins/genetics

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Tytuł:: C/EBP homologous protein deficiency enhances hematopoietic stem cell function via reducing ATF3/ROS-induced cell apoptosis.
Autorzy:: Shi Z; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Diao D; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Zhao Y; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Luo Y; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Li Y; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Liu D; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Zhang K; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Qiu Y; School of Rehabilitation Medicine, Weifang Medical University, Weifang, China.
Yu L; School of Rehabilitation Medicine, Weifang Medical University, Weifang, China.
Song Z; Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.
Ju Z; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2021 Jul; Vol. 20 (7), pp. e13382. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Activating Transcription Factor 3/*metabolism
CCAAT-Enhancer-Binding Proteins/*deficiency
Hematopoietic Stem Cells/*metabolism
Reactive Oxygen Species/*metabolism
Animals ; Apoptosis/physiology ; CCAAT-Enhancer-Binding Proteins/metabolism ; Cell Differentiation ; Hematopoietic Stem Cells/cytology ; Mice ; Protein Deficiency/metabolism

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Skocz do pozycji: 15.

Tytuł:: Laboratory evaluation and prognostication among adults and children with CEBPA-mutant acute myeloid leukemia.
Autorzy:: Mendoza H; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Podoltsev NA; Hematology Section, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Siddon AJ; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Pokaż więcej
Źródło:: International journal of laboratory hematology [Int J Lab Hematol] 2021 Jul; Vol. 43 Suppl 1, pp. 86-95.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Biomarkers, Tumor*
Mutation*
CCAAT-Enhancer-Binding Proteins/*genetics
Leukemia, Myeloid, Acute/*diagnosis
Leukemia, Myeloid, Acute/*genetics
Adult ; Age Factors ; Alleles ; Biomarkers ; CCAAT-Enhancer-Binding Proteins/chemistry ; Child ; Germ-Line Mutation ; Humans ; Nucleophosmin ; Protein Binding ; Protein Interaction Domains and Motifs

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Skocz do pozycji: 16.

Tytuł:: Identification and lineage restriction analyses of preleukemia cells in a sporadic biallelic CEBPA mutated acute myeloid leukemia patient.
Autorzy:: Chen Y; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
Liu Q; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
Shi Z; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
Zhang G; Leukaemia Center, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
Wang M; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
Mi Y; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Disease, Leukaemia Center, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
Wei H; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Disease, Leukaemia Center, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
Wang J; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Disease, Leukaemia Center, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China.; Pokaż więcej
Źródło:: International journal of laboratory hematology [Int J Lab Hematol] 2021 Jun; Vol. 43 (3), pp. e145-e147. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji:: Letter
MeSH Terms:: Alleles*
Mutation*
CCAAT-Enhancer-Binding Proteins/*genetics
Leukemia, Myeloid, Acute/*diagnosis
Leukemia, Myeloid, Acute/*genetics
Preleukemia/*diagnosis
Preleukemia/*genetics
CCAAT-Enhancer-Binding Proteins/metabolism ; Cell Lineage ; Humans ; Prognosis

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Tytuł:: In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.
Autorzy:: Franks JL; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Martinez-Chacin RC; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Wang X; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Tiedemann RL; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.
Bonacci T; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Choudhury R; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Bolhuis DL; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Enrico TP; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Mouery RD; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Damrauer JS; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Yan F; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Harrison JS; Department of Chemistry, University of the Pacific, Stockton, California, United States of America.
Major MB; Department of Cell Biology and Physiology, Department of Otolaryngology, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Hoadley KA; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Suzuki A; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin, Madison, Wisconsin, United States of America.
Rothbart SB; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.
Brown NG; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Emanuele MJ; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2020 Dec 11; Vol. 18 (12), pp. e3000975. Date of Electronic Publication: 2020 Dec 11 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Anaphase-Promoting Complex-Cyclosome/*metabolism
CCAAT-Enhancer-Binding Proteins/*metabolism
Chromatin/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Anaphase-Promoting Complex-Cyclosome/physiology ; CCAAT-Enhancer-Binding Proteins/genetics ; CCAAT-Enhancer-Binding Proteins/physiology ; Cell Cycle/physiology ; Cell Cycle Proteins/metabolism ; Cell Line ; Chromatin/genetics ; Computer Simulation ; HEK293 Cells ; HeLa Cells ; Humans ; Protein Processing, Post-Translational ; Transcription Factors/metabolism ; Ubiquitin-Protein Ligases/physiology ; Ubiquitination

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Skocz do pozycji: 18.

Tytuł:: C/EBPα induces Ebf1 gene expression in common lymphoid progenitors.
Autorzy:: Barberi T; Division of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Cui C; Division of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Department of Physiology, China Medical University, Shenyang, China.
Friedman AD; Division of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Dec 17; Vol. 15 (12), pp. e0244161. Date of Electronic Publication: 2020 Dec 17 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CCAAT-Enhancer-Binding Proteins/*genetics
Lymphoid Progenitor Cells/*metabolism
Trans-Activators/*genetics
Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/metabolism ; CCAAT-Enhancer-Binding Proteins/metabolism ; Cell Lineage ; Cells, Cultured ; Enhancer Elements, Genetic ; Female ; HEK293 Cells ; Humans ; Lymphoid Progenitor Cells/cytology ; Lymphopoiesis ; Male ; Mice ; Mice, Inbred C57BL ; Trans-Activators/metabolism

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Skocz do pozycji: 19.

Tytuł:: The "Janus" Role of C/EBPs Family Members in Cancer Progression.
Autorzy:: Tolomeo M; Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, via del Vespro 129, 90127 Palermo, Italy.
Grimaudo S; Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, via del Vespro 129, 90127 Palermo, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Jun 17; Vol. 21 (12). Date of Electronic Publication: 2020 Jun 17.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Multigene Family*
CCAAT-Enhancer-Binding Proteins/*metabolism
Neoplasms/*etiology
Neoplasms/*metabolism
Animals ; CCAAT-Enhancer-Binding Proteins/chemistry ; CCAAT-Enhancer-Binding Proteins/genetics ; Disease Progression ; Disease Susceptibility ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasms/pathology ; Neoplasms/therapy ; Protein Binding ; Protein Isoforms ; Signal Transduction ; Structure-Activity Relationship

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Skocz do pozycji: 20.

Tytuł:: The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.
Autorzy:: Vaughan RM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Kupai A; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Foley CA; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.
Sagum CA; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX, 78957, USA.
Tibben BM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Eden HE; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Tiedemann RL; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Berryhill CA; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Patel V; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Shaw KM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Krajewski K; Department of Biochemistry and Biophysics, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.
Strahl BD; Department of Biochemistry and Biophysics, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.
Bedford MT; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX, 78957, USA.
Frye SV; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA.
Dickson BM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA.
Rothbart SB; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA. .; Pokaż więcej
Źródło:: Epigenetics & chromatin [Epigenetics Chromatin] 2020 Oct 23; Vol. 13 (1), pp. 44. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Methylation*
Gene Expression Regulation, Neoplastic*
Histone Code*
CCAAT-Enhancer-Binding Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
CCAAT-Enhancer-Binding Proteins/chemistry ; Epigenesis, Genetic ; HCT116 Cells ; HeLa Cells ; Histones/chemistry ; Histones/metabolism ; Humans ; Lysine/metabolism ; Methylation ; Protein Processing, Post-Translational ; Tudor Domain ; Ubiquitin-Protein Ligases/chemistry

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