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Wyszukujesz frazę ""CD4-Positive T-Lymphocytes"" wg kryterium: Temat


Tytuł:
Immune tolerance of food is mediated by layers of CD4 T cell dysfunction.
Autorzy:
Hong SW; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
Krueger PD; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
Osum KC; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
Dileepan T; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
Herman A; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA.
Mueller DL; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.; Division of Rheumatic and Autoimmune Diseases, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Jenkins MK; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA. .; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, USA. .
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Źródło:
Nature [Nature] 2022 Jul; Vol. 607 (7920), pp. 762-768. Date of Electronic Publication: 2022 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/cytology
CD4-Positive T-Lymphocytes*/immunology
Food*
Immune Tolerance*/immunology
Allergens/immunology ; Antibody Formation ; Dietary Proteins/immunology ; Gastrointestinal Tract/cytology ; Gastrointestinal Tract/immunology ; Gliadin/immunology ; Inflammation ; Interleukin-2/immunology ; Liver/cytology ; Liver/immunology ; Lymphoid Tissue/cytology ; Lymphoid Tissue/immunology ; Peptide Fragments/immunology ; T Follicular Helper Cells/cytology ; T Follicular Helper Cells/immunology ; T-Lymphocytes, Regulatory/cytology ; T-Lymphocytes, Regulatory/immunology ; Th1 Cells/cytology ; Th1 Cells/immunology
Czasopismo naukowe
Tytuł:
A CD4+ TNF+ monofunctional memory T-cell response to BCG vaccination is associated with Mycobacterium tuberculosis infection in infants exposed to HIV.
Autorzy:
Warr AJ; Department of Medicine, University of Washington, 750 Republican St, Seattle, WA 98109, USA. Electronic address: .
Anterasian C; Department of Pediatrics, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98105, USA.
Shah JA; Department of Medicine, University of Washington, 750 Republican St, Seattle, WA 98109, USA; Veteran Affairs Puget Sound Healthcare System, 1660 South Columbian Way, Seattle, WA 98108, USA.
De Rosa SC; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave North, E4-200, Seattle, WA 98109, USA; Department of Laboratory Medicine and Pathology, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA.
Nguyen FK; Department of Medicine, University of Washington, 750 Republican St, Seattle, WA 98109, USA.
Maleche-Obimbo E; Department of Paediatrics and Child Health, University of Nairobi, Kenyatta National Hospital, PO Box 20723-00202, Nairobi, Kenya.
Cranmer LM; Department of Pediatrics, Emory University and Children's Healthcare of Atlanta, 100 Woodruff Circle, Atlanta, GA 30322, USA.
Matemo D; Kenyatta National Hospital, PO Box 20723-00202, Nairobi, Kenya.
Mecha J; Kenyatta National Hospital, PO Box 20723-00202, Nairobi, Kenya.
Kinuthia J; Kenyatta National Hospital, PO Box 20723-00202, Nairobi, Kenya.
LaCourse SM; Department of Medicine, University of Washington, 750 Republican St, Seattle, WA 98109, USA; Department of Global Health, University of Washington, 325 9th Ave, Seattle, WA, 98104, USA.
John-Stewart GC; Department of Medicine, University of Washington, 750 Republican St, Seattle, WA 98109, USA; Department of Pediatrics, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98105, USA; Department of Global Health, University of Washington, 325 9th Ave, Seattle, WA, 98104, USA.
Hawn TR; Department of Medicine, University of Washington, 750 Republican St, Seattle, WA 98109, USA.
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Źródło:
EBioMedicine [EBioMedicine] 2022 Jun; Vol. 80, pp. 104023. Date of Electronic Publication: 2022 May 06.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
BCG Vaccine*/administration & dosage
BCG Vaccine*/immunology
CD4-Positive T-Lymphocytes*/drug effects
CD4-Positive T-Lymphocytes*/immunology
HIV Infections*/immunology
HIV Infections*/microbiology
Memory T Cells*/drug effects
Memory T Cells*/immunology
Mycobacterium tuberculosis*
Tuberculosis*/diagnosis
Tuberculosis*/immunology
Tuberculosis*/prevention & control
Tuberculosis*/virology
Antitubercular Agents/administration & dosage ; Cytokines/immunology ; Humans ; Infant ; Infant, Newborn ; Isoniazid/administration & dosage ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł:
CD4+ T-Cell Epitope Prediction by Combined Analysis of Antigen Conformational Flexibility and Peptide-MHCII Binding Affinity.
Autorzy:
Charles T; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.
Moss DL; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.
Bhat P; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.
Moore PW; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.
Kummer NA; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.
Bhattacharya A; Department of Computer Science, Tulane University, New Orleans, Louisiana 70118, United States.
Landry SJ; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.
Mettu RR; Department of Computer Science, Tulane University, New Orleans, Louisiana 70118, United States.
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Źródło:
Biochemistry [Biochemistry] 2022 Aug 02; Vol. 61 (15), pp. 1585-1599. Date of Electronic Publication: 2022 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/metabolism
Epitopes, T-Lymphocyte*/chemistry
Epitopes, T-Lymphocyte*/metabolism
Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Inbred CBA ; Peptide Hydrolases/metabolism ; Peptides/chemistry ; Protein Conformation
Czasopismo naukowe
Tytuł:
Differences in H3K4me3 and chromatin accessibility contribute to altered T-cell receptor signaling in neonatal naïve CD4 T cells.
Autorzy:
Bermick JR; Division of Neonatology, Department of Pediatrics, University of Iowa, Iowa City, IA, USA.; Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Michigan Medicine, Ann Arbor, MI, USA.
Issuree P; Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
denDekker A; Department of Vascular Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Gallagher KA; Department of Vascular Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Santillan D; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA.
Kunkel S; Department of Pathology, Michigan Medicine, Ann Arbor, MI, USA.
Lukacs N; Department of Pathology, Michigan Medicine, Ann Arbor, MI, USA.; Mary H. Weiser Food Allergy Center, Michigan Medicine, Ann Arbor, MI, USA.
Schaller M; Department of Pathology, Michigan Medicine, Ann Arbor, MI, USA.; Pulmonary, Critical Care & Sleep Medicine, University of Florida, Gainesville, FL, USA.
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Źródło:
Immunology and cell biology [Immunol Cell Biol] 2022 Aug; Vol. 100 (7), pp. 562-579. Date of Electronic Publication: 2022 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Chromatin*/metabolism
Adult ; Histones ; Humans ; Infant, Newborn ; Lymphocyte Activation/genetics ; Receptors, Antigen, T-Cell/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
CD9 expression in porcine blood CD4 T cells delineates two subsets with phenotypic characteristics of central and effector memory cells.
Autorzy:
Álvarez B; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain.
Revilla C; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain.
Moreno S; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain.
Jiménez-Marín Á; Grupo de Inmunogenómica y Patogénesis Molecular (IMIBIC), Departamento de Genética, Universidad de Córdoba, Campus Universitario de Rabanales, 14014, Córdoba, Spain.
Ramos E; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain.
Martínez de la Riva P; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain.
Poderoso T; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain.
Garrido JJ; Grupo de Inmunogenómica y Patogénesis Molecular (IMIBIC), Departamento de Genética, Universidad de Córdoba, Campus Universitario de Rabanales, 14014, Córdoba, Spain.
Ezquerra Á; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain. Electronic address: .
Domínguez J; Departamento de Biotecnología, Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, 28040, Spain.
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Źródło:
Developmental and comparative immunology [Dev Comp Immunol] 2022 Aug; Vol. 133, pp. 104431. Date of Electronic Publication: 2022 May 05.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
T-Lymphocyte Subsets*
Animals ; Cell Differentiation ; Immunologic Memory ; Leukocyte Common Antigens ; Phenotype ; Swine
Czasopismo naukowe
Tytuł:
STING modulates necrotic cell death in CD4 T cells via activation of PARP-1/PAR following acute systemic inflammation.
Autorzy:
Luan YY; Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, 100026, China.
Zhang L; Department of emergency, The PLA Rocket Force Characteristic Medical Center, Beijing, 100085, China.
Peng YQ; Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, 100026, China.
Li YY; Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, 100026, China.
Yin CH; Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, 100026, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2022 Aug; Vol. 109, pp. 108809. Date of Electronic Publication: 2022 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/metabolism
Poly(ADP-ribose) Polymerase Inhibitors*
Animals ; Apoptosis Inducing Factor ; Cell Death ; Inflammation ; Mice ; NAD ; Necrosis ; Poly (ADP-Ribose) Polymerase-1/metabolism
Czasopismo naukowe
Tytuł:
RIP2 Contributes to Expanded CD4 T Cell IFN-γ Production during Efferocytosis of Streptococcus pneumoniae -Infected Apoptotic Cells.
Autorzy:
Niño-Castaño VE; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, Sao Paulo, Brazil.; Department of Pathology, Faculty of Health Science, Universidad del Cauca, Popayán, Cauca, Colombia.
Penteado LA; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, Sao Paulo, Brazil.; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil.
Silva-Pereira L; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, Sao Paulo, Brazil.
Bazzano JMR; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, Sao Paulo, Brazil.
Orlando AB; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, Sao Paulo, Brazil.
Salina ACG; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, Sao Paulo, Brazil.; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil.
Dejani NN; Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil.; Department of Physiology and Pathology, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.
Bonato VLD; Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil; and.
Serezani CH; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN.
Medeiros AI; Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, Sao Paulo, Brazil; .
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Źródło:
ImmunoHorizons [Immunohorizons] 2022 Jul 26; Vol. 6 (7), pp. 559-568. Date of Electronic Publication: 2022 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Streptococcus pneumoniae*
Toll-Like Receptor 2*/metabolism
Interferon-gamma/*biosynthesis
Ubiquitin-Protein Ligases/*metabolism
Animals ; Apoptosis ; Interferon-gamma/metabolism ; Mice ; Mice, Inbred C57BL ; Signal Transduction ; Th1 Cells
Czasopismo naukowe
Tytuł:
A Novel Technique for the Generation of Substantial Numbers of Functional Resident T Cells from Kidney Tissue.
Autorzy:
Betjes MGH; Erasmus MC Transplant Institute, Division of Nephrology and Transplantation, Department of Internal Medicine, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
Prevoo F; Erasmus MC Transplant Institute, Division of Nephrology and Transplantation, Department of Internal Medicine, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
van den Bosch TPP; Department of Pathology, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
Klepper M; Erasmus MC Transplant Institute, Division of Nephrology and Transplantation, Department of Internal Medicine, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
Litjens NHR; Erasmus MC Transplant Institute, Division of Nephrology and Transplantation, Department of Internal Medicine, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
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Źródło:
Cells [Cells] 2022 Jul 18; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 18.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
CD8-Positive T-Lymphocytes*
Interleukin-15 ; Interleukin-2 ; Kidney ; Receptors, Antigen, T-Cell
Czasopismo naukowe
Tytuł:
The Role of T Helper 22 Cells in Dermatological Disorders.
Autorzy:
Pan Y; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.; Department of Dermatology, the First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Du D; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.
Wang L; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.
Wang X; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Dermatology, China Institute of Inflammation and Immunology (CIII), Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
He G; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Dermatology, China Institute of Inflammation and Immunology (CIII), Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Jiang X; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.; Laboratory of Dermatology, China Institute of Inflammation and Immunology (CIII), Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Jul 14; Vol. 13, pp. 911546. Date of Electronic Publication: 2022 Jul 14 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review
MeSH Terms:
CD4-Positive T-Lymphocytes*
T-Lymphocytes, Helper-Inducer*
Keratinocytes
Czasopismo naukowe
Tytuł:
Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure.
Autorzy:
Berendam SJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, United States.
Nelson AN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, United States.
Yagnik B; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Goswami R; Department of Pediatrics, Weill Cornell Medicine, New York, NY, United States.
Styles TM; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Neja MA; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.
Phan CT; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.
Dankwa S; Department of Pediatrics, Weill Cornell Medicine, New York, NY, United States.
Byrd AU; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.
Garrido C; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.
Amara RR; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Chahroudi A; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.; Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta and Emory University, Atlanta, GA, United States.
Permar SR; Department of Pediatrics, Weill Cornell Medicine, New York, NY, United States.
Fouda GG; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, United States.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Jul 13; Vol. 13, pp. 885272. Date of Electronic Publication: 2022 Jul 13 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
CD4-Positive T-Lymphocytes*
HIV Infections*
Adult ; Child ; Humans ; Infant ; Secondary Prevention
Czasopismo naukowe
Tytuł:
The CD226/TIGIT axis is involved in T cell hypo-responsiveness appearance in long-term kidney transplant recipients.
Autorzy:
Del Bello A; Nephrology and Organ Transplant Department, CHU Toulouse, 1 av Jean Poulhès, 31059, Toulouse Cedex 9, France. .; Université Paul Sabatier Toulouse III, Toulouse, France. .; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), INSERM UMR1043-CNRS 5282, Toulouse, France. .
Gouin A; Nephrology and Organ Transplant Department, CHU Toulouse, 1 av Jean Poulhès, 31059, Toulouse Cedex 9, France.; Université Paul Sabatier Toulouse III, Toulouse, France.; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), INSERM UMR1043-CNRS 5282, Toulouse, France.
Chaubet C; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), INSERM UMR1043-CNRS 5282, Toulouse, France.
Kamar N; Nephrology and Organ Transplant Department, CHU Toulouse, 1 av Jean Poulhès, 31059, Toulouse Cedex 9, France.; Université Paul Sabatier Toulouse III, Toulouse, France.; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), INSERM UMR1043-CNRS 5282, Toulouse, France.
Treiner E; Université Paul Sabatier Toulouse III, Toulouse, France. .; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), INSERM UMR1043-CNRS 5282, Toulouse, France. .; Laboratory of Immunology, Biology Department, CHU Toulouse, Toulouse, France. .; Infinity-Inserm UMR 1291-CNRS UMR5051, CHU Purpan, BP3028, 31024, Toulouse Cedex 3, France. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 12; Vol. 12 (1), pp. 11821. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Differentiation, T-Lymphocyte*/immunology
CD4-Positive T-Lymphocytes*
Kidney Transplantation*
Receptors, Immunologic*/immunology
Cytokines/immunology ; Humans ; Transplantation Immunology
Czasopismo naukowe
Tytuł:
Th1-Dominant CD4 T Cells Orchestrate Endogenous Systematic Antitumor Immune Memory After Cryo-Thermal Therapy.
Autorzy:
Peng P; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Lou Y; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Wang J; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Wang S; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Liu P; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Xu LX; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Jul 08; Vol. 13, pp. 944115. Date of Electronic Publication: 2022 Jul 08 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
CD8-Positive T-Lymphocytes*
Immunologic Memory ; Immunotherapy ; Immunotherapy, Adoptive
Czasopismo naukowe
Tytuł:
The pro-inflammatory effect of triglyceride on human CD4 T cells and experimental autoimmune uveitis.
Autorzy:
Tan S; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Feng X; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Liu Z; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Wang Q; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Jiang Q; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Ye X; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Li H; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Su G; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Zhou C; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Wang Y; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Yang P; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, PR China. Electronic address: .
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Źródło:
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2022 Jul; Vol. 240, pp. 109056. Date of Electronic Publication: 2022 May 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autoimmune Diseases*
Behcet Syndrome*
CD4-Positive T-Lymphocytes*
Uveitis*/etiology
Animals ; Disease Models, Animal ; Humans ; Interleukin-17/metabolism ; Mice ; Th1 Cells ; Th17 Cells ; Triglycerides/metabolism ; Triglycerides/pharmacology
Czasopismo naukowe
Tytuł:
CD4 Cytotoxic T cells - Phenotype, Function and Transcriptional Networks Controlling Their Differentiation Pathways.
Autorzy:
Preglej T; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Austria.
Ellmeier W; Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Austria. Electronic address: .
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Źródło:
Immunology letters [Immunol Lett] 2022 Jul; Vol. 247, pp. 27-42. Date of Electronic Publication: 2022 May 11.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes*
T-Lymphocytes, Cytotoxic*
Gene Regulatory Networks ; Phenotype ; T-Lymphocytes, Helper-Inducer
Czasopismo naukowe
Tytuł:
Role of Glutaminase 2 in Promoting CD4+ T Cell Production of Interleukin-2 by Supporting Antioxidant Defense in Systemic Lupus Erythematosus.
Autorzy:
Hisada R; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Yoshida N; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Orite SYK; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Umeda M; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Burbano C; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Scherlinger M; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Kono M; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Krishfield S; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Tsokos GC; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
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Źródło:
Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2022 Jul; Vol. 74 (7), pp. 1204-1210. Date of Electronic Publication: 2022 May 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/metabolism
CD4-Positive T-Lymphocytes*/metabolism
Glutaminase*/metabolism
Interleukin-2*/metabolism
Lupus Erythematosus, Systemic*/immunology
Animals ; Mice ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Single-Cell Profiling of Latently SIV-Infected CD4 T Cells Directly Ex Vivo to Reveal Host Factors Supporting Reservoir Persistence.
Autorzy:
Tokarev A; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
Machmach K; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
Creegan M; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
Kim D; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
Eller MA; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
Bolton DL; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
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Źródło:
Microbiology spectrum [Microbiol Spectr] 2022 Jun 29; Vol. 10 (3), pp. e0060422. Date of Electronic Publication: 2022 May 05.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/virology
Simian Acquired Immunodeficiency Syndrome*/virology
Simian Immunodeficiency Virus*/genetics
Virus Latency*
Animals ; Macaca mulatta/genetics ; Membrane Proteins ; RNA, Messenger ; Viral Load ; Virus Replication
Czasopismo naukowe
Tytuł:
Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4 T cells in ulcerative colitis.
Autorzy:
Xu HM; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Yuexiu District, No. 1, Panfu Road, Guangzhou, 510180, Guangdong, China.
Xu J; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Yuexiu District, No. 1, Panfu Road, Guangzhou, 510180, Guangdong, China.
Yang MF; Department of Hematology, Yantian District People's Hospital, Shenzhen, 518020, Guangdong, China.
Liang YJ; Shenzhen Kangning Hospital, Shenzhen, 518020, Guangdong, China.
Peng QZ; Department of Pathology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China.
Zhang Y; Department of Medical Administration, Huizhou Institute of Occupational Diseases Control and Prevention, Huizhou, 516000, Guangdong, China.
Tian CM; Department of Emergency, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China.
Nie YQ; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Yuexiu District, No. 1, Panfu Road, Guangzhou, 510180, Guangdong, China. .
Wang LS; Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Luohu District, No. 1017, Dongmen North Road, Shenzhen, 518020, Guangdong, China. .
Yao J; Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Luohu District, No. 1017, Dongmen North Road, Shenzhen, 518020, Guangdong, China. .
Li DF; Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Luohu District, No. 1017, Dongmen North Road, Shenzhen, 518020, Guangdong, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2022 Jun 27; Vol. 20 (1), pp. 289. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes*/metabolism
CD8-Positive T-Lymphocytes*/metabolism
Colitis, Ulcerative*/genetics
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Epigenesis, Genetic*
Transcription Factors*/genetics
Transcription Factors*/metabolism
Animals ; Colitis/chemically induced ; Colitis/genetics ; Colon/pathology ; Cytokines/metabolism ; DNA Methylation ; Dextran Sulfate/adverse effects ; Dextran Sulfate/metabolism ; Humans ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
CD96 Downregulation Promotes the Immune Response of CD4 T Cells and Associates with Ankylosing Spondylitis.
Autorzy:
Wu F; Zhejiang Chinese Medical University, Hangzhou, China.
Yang H; Zhejiang Chinese Medical University, Hangzhou, China.
Xu X; Zhejiang Chinese Medical University, Hangzhou, China.
Ren C; Zhejiang Chinese Medical University, Hangzhou, China.
Zheng Y; Zhejiang Chinese Medical University, Hangzhou, China.
Zhang H; Zhejiang Chinese Medical University, Hangzhou, China.
Cai B; The Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Qiu R; The Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Ren W; The Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Quan R; The Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Jun 19; Vol. 2022, pp. 3946754. Date of Electronic Publication: 2022 Jun 19 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Spondylitis, Ankylosing*/metabolism
Antigens, CD/metabolism ; Down-Regulation ; Humans ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Increased Level of Tim-3 T Cells With Altered Function Might Be Associated With Lower Extremity Arteriosclerosis Obliterans.
Autorzy:
Cui L; Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, China.
Chen L; Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, China.
Dai Y; Department of General Surgery, Xinhua Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China.
Ou J; Department of General Surgery, Xinhua Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China.
Qiu M; Department of General Surgery, Xinhua Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China.; Department of General Surgery, Shigatse People's Hospital, Shigatse, China.
Wang S; Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Jun 10; Vol. 13, pp. 871362. Date of Electronic Publication: 2022 Jun 10 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arteriosclerosis Obliterans*/immunology
CD4-Positive T-Lymphocytes*/immunology
Hepatitis A Virus Cellular Receptor 2*/immunology
Hepatitis A Virus Cellular Receptor 2*/metabolism
Programmed Cell Death 1 Receptor*/immunology
Adult ; Humans ; Lower Extremity
Czasopismo naukowe
Tytuł:
Towards a unified model of naive T cell dynamics across the lifespan.
Autorzy:
Rane S; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, United States.; Irving Institute for Cancer Dynamics, Columbia University, New York, United States.
Hogan T; Institute of Immunity and Transplantation, Division of Infection and Immunity, UCL, Royal Free Hospital, London, United Kingdom.
Lee E; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, United States.
Seddon B; Institute of Immunity and Transplantation, Division of Infection and Immunity, UCL, Royal Free Hospital, London, United Kingdom.
Yates AJ; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, United States.
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Źródło:
ELife [Elife] 2022 Jun 09; Vol. 11. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Longevity*
Animals ; CD8-Positive T-Lymphocytes ; Homeostasis ; Immunologic Memory ; Mice
Czasopismo naukowe

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